gabapentin and baclofen

gabapentin has been researched along with baclofen in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.27)18.7374
1990's6 (7.59)18.2507
2000's30 (37.97)29.6817
2010's32 (40.51)24.3611
2020's10 (12.66)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Reimann, W1
Hill, DR; Suman-Chauhan, N; Webdale, L; Woodruff, GN1
Lönnecker, S; Paulus, W; Steinhoff, BJ; Ziemann, U1
Averbuch-Heller, L; Büttner, U; Fuhry, L; Ganser, GL; Heide, W; Leigh, RJ; Rottach, KG; Tusa, RJ1
Bergler, W; Hein, G; Petroianu, A; Petroianu, G; Rüfer, R1
Lorenzo, N; Stringer, JL1
Leigh, RJ; Ramat, S1
Bergler, W; Hein, G; Petroianu, G; Rüfer, R; Stegmeier-Petroianu, A1
Capogna, M; Fox, A; Froestl, W; Kesingland, A; Naeem, S; Patel, S; Urban, L1
Krach, LE1
Bertrand, S; Chronwall, BM; Lacaille, JC; Low, MJ; Metters, K; Morris, SJ; Ng, GY; Nouel, D; O'Neill, GP; Purisai, MG; Robitaille, R; Severidt, MW; Wolfe, SE1
Francisco, GE; Huls, C; Kothari, S1
Schapiro, RT1
Rösche, J1
Fabre, K; Smet-Dieleman, H; Zeyen, T1
Bertrand, S; Lacaille, JC; Morin, F1
Bertrand, S; Lacaille, JC; Morin, F; Nagy, F; Nouel, D1
Enna, SJ1
Kerr, DI; Marino, V; Ong, J; Parker, DA1
García-Regata, O; González-Macías, J; Hernández, JL; Jiménez, V; Pajarón, M; Ramos-Estébanez, C1
Elovic, E; Lombard, L; Zafonte, R1
Anagnostouli, M; Karandreas, N; Sarrigiannis, P; Tsakanicas, C1
De Vry, J; Jentzsch, KR1
Watson, CP1
Choudhuri, I; Gottlob, I; Sarvananthan, N1
Heinzerling, KG; Ling, W; Liu, J; Peck, JA; Roll, J; Shoptaw, S; Yang, X1
Cutrignelli, A; Denora, N; Laquintana, V; Latrofa, A; Liso, G; Lopedota, A; Trapani, A; Trapani, G1
Aymon, D; Jichlinski, P; Praz, V; Wisard, M1
Hutson, PH; McDonald, LM; Sheppard, WF; Sohal, B; Staveley, SM; Tattersall, FD1
Taira, T1
Jahn, K; Kalla, R; Rettinger, N; Spiegel, R; Strupp, M; Wagner, J1
D'Innocenzo, D; Di Benedetto, G; Grenga, R; Nebbioso, M; Rapone, S1
Gottlob, I; McLean, RJ1
Kuks, JB; Lapeyre, E; Meijler, WJ1
Lagrèze, WA; Pieh-Beisse, C1
Blaskiewicz, R; Goldkamp, J; Myles, T1
Leigh, RJ; Optican, LM; Shaikh, AG; Thurtell, MJ1
Kennard, C; Mehta, AR1
Heinzlef, O; Monteil-Roch, I1
Cohen, SM; Misono, S1
Chen, RX; Hou, XL; Lv, Y; Wu, YL; Xu, XQ; Zhu, Y1
Benoliel, R; Haviv, Y; Sharav, Y; Zadik, Y1
Bak, K; Bleeker, J; Cavaletti, G; Chauhan, C; Dworkin, RH; Gavin, P; Hershman, DL; Lacchetti, C; Lavino, A; Lavoie Smith, EM; Loprinzi, CL; Lustberg, MB; Paice, J; Schneider, B; Smith, ML; Smith, T; Terstriep, S; Wagner-Johnston, N1
Dargan, PI; Green, JL; Kapil, V; Le Lait, MC; Wood, DM1
Fox, M; Schneemann, M; Steger, M1
Banov, D; Bassani, AS1
Trojano, M1
Comi, G; Gold, R; Hartung, HP; Montalban, X; Otero-Romero, S; Sastre-Garriga, J; Soelberg Sørensen, P; Thompson, AJ; Vermersch, P1
Andrews, R; Nahar, L; Patel, R; Paterson, S; Smith, A1
Lyon, J1
Bardenheuer, HJ; Hollmann, MW; Kessler, J; Kohse, EK1
Harvey, A; Reddihough, D; Scheinberg, A; Williams, K1
Dodridge, CS; Evans, JR; Garcia-Finana, M; Hanna, K; Howard, C; Jarvis, KA; Maan, T; MacDiarmid, SL; Noonan, CP; North, L; Rodgers, H; Rowe, FJ1
Ahmad, SU; Kumar, J; Mohamed, IN; Pakri Mohamed, RM1
Amato, L; Amin-Esmaeili, M; Gholami, J; Hoseinie, L; Rahimi-Movaghar, A; Yousefi-Nooraie, R1
Cruccu, G; Di Stefano, G; Truini, A1
Dorsey, SG; Griffioen, MA; O'Toole, RV; Renn, CL; Ziegler, ML1
Hiremath, S; Sriperumbuduri, S1
Chen, Q; Ding, H; Dong, R; Lv, H; Pan, J; Qiu, Z; Shi, C; Xu, X; Yu, L; Yu, Y; Zhang, M1
Alho, H; Castrén, S; Mäkelä, N1
Dong, R; Qiu, Z; Xu, X; Yu, L1
Naik, RD; Vaezi, MF1
Yuan, SM1
Aletraris, L; Paino, M; Roman, PM1
Centonze, D; Comi, G; Leocani, L; Otero-Romero, S; Solari, A1
Hughes, P; Ostrach, B1
Murphy, KG; Nahar, LK; Paterson, S1
Barnett, ML; Bykov, K; Gagne, JJ; Glynn, RJ; Khan, NF1
Alizadeh-Sani, M; Foroumadi, A; Hasanvand, Z; Jouyban, A; Mohammadian, E; Rahimpour, E1
Davis, JF; Mata, DC1
Fomin, V; Goodman, RP; Luther, J; Patel, SJ; Schaefer, E; Shay, JES; Vannier, AGL1
Dahal, S; Khati, N; Maharjan, G; Yadav, P; Yadav, SK1
Chen, J; Guo, X; Jiang, B; Liang, B; Wang, W1

Reviews

29 review(s) available for gabapentin and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Neuropharmacologic aspects of the ocular motor system and the treatment of abnormal eye movements.
    Current opinion in neurology, 1999, Volume: 12, Issue:1

    Topics: Abducens Nerve; Acetates; Amines; Baclofen; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Eye Movements; Fixation, Ocular; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglossal Nerve; Ocular Motility Disorders; Vestibular Nerve; Visual Pathways

1999
Pharmacotherapy of spasticity: oral medications and intrathecal baclofen.
    Journal of child neurology, 2001, Volume: 16, Issue:1

    Topics: Acetates; Administration, Oral; Amines; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Cerebral Palsy; Child, Preschool; Cyclohexanecarboxylic Acids; Dantrolene; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Muscle Relaxants, Central

2001
GABA agonists and gabapentin for spastic hypertonia.
    Physical medicine and rehabilitation clinics of North America, 2001, Volume: 12, Issue:4

    Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Diazepam; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Spasticity

2001
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis.
    Current neurology and neuroscience reports, 2001, Volume: 1, Issue:3

    Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabinoids; Causalgia; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Dystonia; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Mechanoreceptors; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Pain; Physical Therapy Modalities; Receptors, GABA-A; Receptors, GABA-B; Relaxation Therapy; Trigeminal Neuralgia

2001
A GABA(B) mystery: the search for pharmacologically distinct GABA(B) receptors.
    Molecular interventions, 2001, Volume: 1, Issue:4

    Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzylamines; Cyclohexanecarboxylic Acids; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Molecular Structure; Morpholines; Phosphinic Acids; Protein Isoforms; Receptors, GABA-B; RNA, Messenger

2001
Gabapentin for intractable hiccup.
    The American journal of medicine, 2004, Aug-15, Volume: 117, Issue:4

    Topics: Acetates; Aged; Amines; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Hiccup; Humans; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed

2004
Antispasticity medications: uses and limitations of enteral therapy.
    American journal of physical medicine & rehabilitation, 2004, Volume: 83, Issue:10 Suppl

    Topics: 4-Aminopyridine; Acetates; Adrenergic alpha-Agonists; Amines; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Cyproheptadine; Dantrolene; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Glycine; Humans; Muscle Relaxants, Central; Muscle Spasticity; Neuroprotective Agents; Piracetam; Serotonin Antagonists

2004
Management issues of neuropathic trigeminal pain from a medical perspective.
    Journal of orofacial pain, 2004,Fall, Volume: 18, Issue:4

    Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Facial Neuralgia; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lamotrigine; Narcotics; Phenytoin; Triazines; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2004
[Chronic intrathecal drug administration for the control of intractable pain].
    Brain and nerve = Shinkei kenkyu no shinpo, 2008, Volume: 60, Issue:5

    Topics: Amines; Analgesics, Opioid; Anesthetics, Local; Baclofen; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Morphine; Neoplasms; Neuralgia; omega-Conotoxins; Pain, Intractable

2008
[Pharmacotherapy of central oculomotor disorders].
    Der Nervenarzt, 2008, Volume: 79, Issue:12

    Topics: 4-Aminopyridine; Amifampridine; Amines; Baclofen; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Memantine; Nystagmus, Pathologic; Vestibular Nuclei

2008
[Nystagmus in ophthalmology].
    La Clinica terapeutica, 2009, Volume: 160, Issue:2

    Topics: Amines; Baclofen; Cyclohexanecarboxylic Acids; Diagnostic Techniques, Ophthalmological; Eye Diseases; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Nystagmus, Pathologic; Nystagmus, Physiologic; Ophthalmologic Surgical Procedures

2009
The pharmacological treatment of nystagmus: a review.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:11

    Topics: Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Nystagmus, Congenital; Nystagmus, Pathologic; Randomized Controlled Trials as Topic

2009
Spasticity: revisiting the role and the individual value of several pharmacological treatments.
    NeuroRehabilitation, 2010, Volume: 27, Issue:2

    Topics: Amines; Baclofen; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Relaxants, Central; Muscle Spasticity; Recovery of Function; Treatment Outcome

2010
The pharmacological treatment of acquired nystagmus.
    Practical neurology, 2012, Volume: 12, Issue:3

    Topics: Amines; Aminopyridines; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Nystagmus, Congenital; Nystagmus, Pathologic; Randomized Controlled Trials as Topic; Treatment Outcome

2012
[Pharmacological treatment of spasticity in multiple sclerosis].
    Revue neurologique, 2012, Volume: 168 Suppl 3

    Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Nerve Block; Neuromuscular Agents; Randomized Controlled Trials as Topic; Spasm; Vigabatrin

2012
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2013, Volume: 148, Issue:3

    Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Pregabalin; Quality of Life

2013
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jun-20, Volume: 32, Issue:18

    Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States

2014
Systemic review: the pathogenesis and pharmacological treatment of hiccups.
    Alimentary pharmacology & therapeutics, 2015, Volume: 42, Issue:9

    Topics: Amines; Anticonvulsants; Antipsychotic Agents; Baclofen; Benzamides; Chlorpromazine; Cyclohexanecarboxylic Acids; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Metoclopramide; Randomized Controlled Trials as Topic; Treatment Outcome

2015
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2016, Volume: 22, Issue:11

    Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Phenol

2016
Chronic Hiccups: An Underestimated Problem.
    Anesthesia and analgesia, 2017, Volume: 125, Issue:4

    Topics: Amines; Anesthesiology; Baclofen; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Muscle Relaxants, Central

2017
Interventions for eye movement disorders due to acquired brain injury.
    The Cochrane database of systematic reviews, 2018, 03-05, Volume: 3

    Topics: 4-Aminopyridine; Abducens Nerve Diseases; Amifampridine; Amines; Baclofen; Botulinum Toxins; Brain Injuries; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Nystagmus, Pathologic; Ocular Motility Disorders; Randomized Controlled Trials as Topic; Vision, Binocular; Watchful Waiting

2018
Novel Pharmacotherapeutic Approaches in Treatment of Alcohol Addiction.
    Current drug targets, 2018, Volume: 19, Issue:12

    Topics: Alcohol Deterrents; Alcoholism; Animals; Aripiprazole; Baclofen; Cyclopentanes; Gabapentin; Humans; Naltrexone; Quetiapine Fumarate

2018
Pharmacological therapies for management of opium withdrawal.
    The Cochrane database of systematic reviews, 2018, 06-21, Volume: 6

    Topics: Amantadine; Amines; Baclofen; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Opium; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Tramadol

2018
Current and Innovative Pharmacological Options to Treat Typical and Atypical Trigeminal Neuralgia.
    Drugs, 2018, Volume: 78, Issue:14

    Topics: Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Drug Therapy, Combination; Gabapentin; Humans; Lamotrigine; Oxcarbazepine; Phenyl Ethers; Proline; Sodium Channel Blockers; Trigeminal Neuralgia

2018
The case for cautious consumption: NSAIDs in chronic kidney disease.
    Current opinion in nephrology and hypertension, 2019, Volume: 28, Issue:2

    Topics: Acute Kidney Injury; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Cost-Benefit Analysis; Gabapentin; Humans; Pain; Pregabalin; Renal Insufficiency, Chronic; Tramadol

2019
Selecting an appropriate alcohol pharmacotherapy: review of recent findings.
    Current opinion in psychiatry, 2019, Volume: 32, Issue:4

    Topics: Acamprosate; Alcoholism; Antidepressive Agents; Baclofen; Cholinergic Agonists; Disulfiram; Gabapentin; Humans; Naltrexone; Ondansetron; Randomized Controlled Trials as Topic; Treatment Outcome

2019
Myocardial Ischemia Presenting with Hiccups.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:5

    Topics: Baclofen; Electrocardiography; GABA-B Receptor Agonists; Gabapentin; Hiccup; Humans; Myocardial Infarction; Myocardial Ischemia; Treatment Outcome

2019
Derivatization of γ-Amino Butyric Acid Analogues for Their Determination in the Biological Samples and Pharmaceutical Preparations: A Comprehensive Review.
    Critical reviews in analytical chemistry, 2022, Volume: 52, Issue:8

    Topics: Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Pregabalin; Vigabatrin

2022

Trials

3 trial(s) available for gabapentin and baclofen

ArticleYear
A double-blind controlled study of gabapentin and baclofen as treatment for acquired nystagmus.
    Annals of neurology, 1997, Volume: 41, Issue:6

    Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Double-Blind Method; Eye Movements; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nystagmus, Pathologic; Treatment Outcome; Visual Acuity

1997
Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence.
    Drug and alcohol dependence, 2006, Dec-01, Volume: 85, Issue:3

    Topics: Adult; Amines; Anti-Anxiety Agents; Baclofen; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Demography; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methamphetamine; Psychology; Substance-Related Disorders; Surveys and Questionnaires

2006
Randomised clinical trial: gabapentin vs baclofen in the treatment of suspected refractory gastro-oesophageal reflux-induced chronic cough.
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:6

    Topics: Adult; Analgesics; Baclofen; Chronic Disease; Cough; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gabapentin; Gastroesophageal Reflux; Humans; Male; Middle Aged; Muscle Relaxants, Central; Treatment Outcome

2019

Other Studies

47 other study(ies) available for gabapentin and baclofen

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action?
    European journal of pharmacology, 1983, Oct-28, Volume: 94, Issue:3-4

    Topics: Acetates; Amines; Animals; Baclofen; Bicuculline; Binding Sites; Caudate Nucleus; Cyclohexanecarboxylic Acids; Dopamine; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Rabbits

1983
Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies.
    European journal of pharmacology, 1993, Feb-15, Volume: 244, Issue:3

    Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Baclofen; Binding Sites; Cell Membrane; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine

1993
Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.
    Annals of neurology, 1996, Volume: 40, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Acetates; Adult; Amines; Anticonvulsants; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Differential Threshold; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Motor Cortex; Physical Stimulation; Transcranial Magnetic Stimulation; Vigabatrin

1996
[ETICS Study: Empirical therapy of idiopathic chronic singultus].
    Zeitschrift fur Gastroenterologie, 1998, Volume: 36, Issue:7

    Topics: Acetates; Aged; Aged, 80 and over; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Omeprazole; Treatment Outcome

1998
The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation.
    Epilepsy research, 1999, Volume: 33, Issue:2-3

    Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dentate Gyrus; Electric Stimulation; GABA Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B

1999
Gabapentin "add-on therapy" for idiopathic chronic hiccup (ICH).
    Journal of clinical gastroenterology, 2000, Volume: 30, Issue:3

    Topics: Acetates; Aged; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Muscle Relaxants, Central; Omeprazole; Treatment Outcome

2000
The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat.
    Pain, 2001, Feb-15, Volume: 90, Issue:3

    Topics: Acetates; Amines; Analgesics; Animals; Baclofen; Cyclohexanecarboxylic Acids; Electric Stimulation; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; In Vitro Techniques; Inflammation; Neuralgia; Rats; Rats, Wistar; Spinal Nerve Roots

2001
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Baclofen; Calcium Channels; Calcium Signaling; Cyclohexanecarboxylic Acids; GABA Agonists; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Transgenic; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B

2001
Treatment of spasticity.
    Spinal cord, 2002, Volume: 40, Issue:6

    Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Spasticity; Paralysis; Rhizotomy

2002
Improvement of acquired pendular nystagmus by gabapentin: case report.
    Bulletin de la Societe belge d'ophtalmologie, 2001, Issue:282

    Topics: Acetates; Administration, Oral; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Multiple Sclerosis; Nystagmus, Pathologic; Treatment Outcome

2001
Different actions of gabapentin and baclofen in hippocampus from weaver mice.
    Hippocampus, 2003, Volume: 13, Issue:4

    Topics: Acetates; Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Down-Regulation; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neural Inhibition; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Receptors, GABA-B; Species Specificity; Synaptic Transmission

2003
Gabapentin actions on Kir3 currents and N-type Ca2+ channels via GABAB receptors in hippocampal pyramidal cells.
    Synapse (New York, N.Y.), 2003, Volume: 50, Issue:2

    Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Baclofen; Barium; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Membrane; Cesium; Cyclohexanecarboxylic Acids; Epilepsy; Ethylmaleimide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gabapentin; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hippocampus; Male; omega-Conotoxin GVIA; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B

2003
Gabapentin activates presynaptic GABAB heteroreceptors in rat cortical slices.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Morpholines; Neocortex; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Presynaptic; Tritium

2004
Spastic paretic hemifacial contracture (SPHC) in a patient with multiple sclerosis. A clinical, EMG and neuroimaging study.
    Neurophysiologie clinique = Clinical neurophysiology, 2004, Volume: 34, Issue:3-4

    Topics: Adult; Amines; Baclofen; Blinking; Brain; Clonazepam; Cyclohexanecarboxylic Acids; Electromyography; Evoked Potentials; Excitatory Amino Acid Antagonists; Facial Muscles; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Magnetic Resonance Imaging; Multiple Sclerosis; Neurons; Pons

2004
Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: Alkanesulfonates; Amines; Amitriptyline; Animals; Baclofen; Behavior, Animal; Benzoxazines; Carbamazepine; Cyclohexanecarboxylic Acids; Cyclohexanols; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Indans; Male; Molecular Structure; Morphine; Morpholines; Naphthalenes; Nitriles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonic Acids

2004
Survey of management of acquired nystagmus in the United Kingdom.
    Eye (London, England), 2007, Volume: 21, Issue:9

    Topics: Amines; Baclofen; Cyclohexanecarboxylic Acids; Drug Utilization; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Health Care Surveys; Humans; Multiple Sclerosis; Neoplasms; Neurology; Nystagmus, Pathologic; Ophthalmology; Professional Practice; Referral and Consultation; Stroke; Treatment Outcome; United Kingdom; Vestibular Diseases

2007
Comparative effects of some hydrophilic excipients on the rate of gabapentin and baclofen lactamization in lyophilized formulations.
    International journal of pharmaceutics, 2007, Mar-06, Volume: 332, Issue:1-2

    Topics: Amines; Anticonvulsants; Baclofen; beta-Cyclodextrins; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Stability; Excipients; Freeze Drying; Gabapentin; gamma-Aminobutyric Acid; Humidity; Kinetics; Lactams; Lactose; Mannitol; Models, Chemical; Molecular Structure; Parasympatholytics; Povidone; Raffinose; Technology, Pharmaceutical; Temperature; Thermogravimetry; Trehalose; Water

2007
A case report on idiopathic recurrent priapism.
    Andrologia, 2007, Volume: 39, Issue:6

    Topics: Adult; Amines; Androgen Antagonists; Baclofen; Cyclohexanecarboxylic Acids; Cyproterone Acetate; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Relaxants, Central; Priapism; Secondary Prevention

2007
Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats.
    Psychopharmacology, 2008, Volume: 197, Issue:4

    Topics: Administration, Oral; Amines; Animals; Anticonvulsants; Azabicyclo Compounds; Baclofen; Benzodiazepines; Bicuculline; Brain; Cyclohexanecarboxylic Acids; Discrimination Learning; Dose-Response Relationship, Drug; GABA Agents; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Generalization, Stimulus; Hypnotics and Sedatives; Injections, Intraperitoneal; Isoxazoles; Male; Nipecotic Acids; Piperazines; Pyridines; Rats; Thiophenes; Tiagabine; Zolpidem

2008
[Pharmacological treatment of nystagmus].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2011, Volume: 108, Issue:2

    Topics: 4-Aminopyridine; Amines; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dopamine Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Relaxants, Central; Nystagmus, Pathologic; Potassium Channel Blockers

2011
Stiff person syndrome and pregnancy.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:2 Pt 2

    Topics: Adult; Amines; Baclofen; Cesarean Section; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Muscle Relaxants, Central; Prednisone; Pregnancy; Spasm; Stiff-Person Syndrome; Treatment Outcome

2011
Pharmacological tests of hypotheses for acquired pendular nystagmus.
    Annals of the New York Academy of Sciences, 2011, Volume: 1233

    Topics: Amines; Baclofen; Cerebellar Cortex; Cyclohexanecarboxylic Acids; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Models, Neurological; Multiple Sclerosis; Myoclonus; Nystagmus, Pathologic; Olivary Nucleus

2011
Evaluation of two modified quick, easy, cheap, effective, rugged and safe (QuEChERS) sample preparation methods for the analysis of baclofen and gabapentin in feeds by liquid chromatography tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 88

    Topics: Acetonitriles; Amines; Animal Feed; Baclofen; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Formates; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Mass Spectrometry; Methanol; Reproducibility of Results; Time Factors; Water

2014
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2014
Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK.
    British journal of clinical pharmacology, 2014, Volume: 78, Issue:1

    Topics: Adolescent; Adult; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Illicit Drugs; Male; Middle Aged; Pregabalin; Prescription Drug Misuse; United Kingdom; Young Adult

2014
Evaluation of the Percutaneous Absorption of Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen, in Compounded Transdermal Pain Formulations, Using the Franz Finite Dose Model.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:2

    Topics: Administration, Cutaneous; Aged; Amines; Baclofen; Clonidine; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Middle Aged; Organ Culture Techniques; Pain; Skin Absorption

2016
THC:CBD Observational Study Data: Evolution of Resistant MS Spasticity and Associated Symptoms.
    European neurology, 2016, Volume: 75 Suppl 1

    Topics: Adult; Amines; Baclofen; Calcium Channel Blockers; Cannabidiol; Cohort Studies; Cyclohexanecarboxylic Acids; Dronabinol; Drug Combinations; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Italy; Male; Medical Marijuana; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Observational Studies as Topic; Oral Sprays; Plant Extracts; Pregabalin; Prospective Studies; Treatment Outcome

2016
Validated Method for the Screening and Quantification of Baclofen, Gabapentin and Pregabalin in Human Post-Mortem Whole Blood Using Protein Precipitation and Liquid Chromatography-Tandem Mass Spectrometry.
    Journal of analytical toxicology, 2017, Jun-01, Volume: 41, Issue:5

    Topics: Amines; Autopsy; Baclofen; Chemical Precipitation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Reproducibility of Results; Tandem Mass Spectrometry

2017
More Treatments on Deck for Alcohol Use Disorder.
    JAMA, 2017, Jun-13, Volume: 317, Issue:22

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Amines; Baclofen; Cyclohexanecarboxylic Acids; Cytidine Diphosphate Choline; Disulfiram; Drug Repositioning; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Mifepristone; Naltrexone; National Institute on Alcohol Abuse and Alcoholism (U.S.); Off-Label Use; Patient Acceptance of Health Care; Taurine; Topiramate; United States; Varenicline

2017
Oral medication prescription practices of tertiary-based specialists for dystonia in children with cerebral palsy.
    Journal of paediatrics and child health, 2018, Volume: 54, Issue:4

    Topics: Administration, Oral; Adolescent; Australia; Baclofen; Central Nervous System Agents; Cerebral Palsy; Child; Child, Preschool; Cross-Sectional Studies; Dystonia; Gabapentin; Health Care Surveys; Humans; Infant; Muscle Relaxants, Central; Practice Patterns, Physicians'; Tertiary Care Centers

2018
Change in Pain Score after Administration of Analgesics for Lower Extremity Fracture Pain during Hospitalization.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2019, Volume: 20, Issue:2

    Topics: Adult; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents; Baclofen; Bones of Lower Extremity; Cohort Studies; Duloxetine Hydrochloride; Female; Fractures, Bone; Gabapentin; Hospitalization; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pain Management; Pain Measurement; Pregabalin; Retrospective Studies

2019
Editorial: breaking the cycle of cough in GERD-neuromodulators to the rescue? Authors' reply.
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:9

    Topics: Baclofen; Cough; Gabapentin; Gastroesophageal Reflux; Humans; Neurotransmitter Agents

2019
Editorial: breaking the cycle of cough in GERD-neuromodulators to the rescue?
    Alimentary pharmacology & therapeutics, 2019, Volume: 49, Issue:9

    Topics: Baclofen; Cough; Gabapentin; Gastroesophageal Reflux; Humans; Neurotransmitter Agents

2019
The use of off-label medications in substance abuse treatment programs.
    Substance abuse, 2020, Volume: 41, Issue:3

    Topics: Accreditation; Adrenergic alpha-2 Receptor Agonists; Anticonvulsants; Antiemetics; Baclofen; Clonidine; Excitatory Amino Acid Antagonists; GABA Agents; Gabapentin; Health Facility Size; Humans; Logistic Models; Off-Label Use; Ondansetron; Practice Patterns, Physicians'; Substance Abuse Treatment Centers; Substance-Related Disorders; Time Factors; Topiramate; United States; Valproic Acid

2020
Italian consensus on treatment of spasticity in multiple sclerosis.
    European journal of neurology, 2020, Volume: 27, Issue:3

    Topics: Baclofen; Botulinum Toxins; Clonidine; Consensus; Disease Management; Gabapentin; Humans; Injections, Intramuscular; Italy; Multiple Sclerosis; Muscle Spasticity; Quality of Life; Transcutaneous Electric Nerve Stimulation

2020
Trends in exposure to over-reach: a comment on the methodology of Reynolds et al. 2019.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:1

    Topics: Baclofen; Gabapentin; Humans; Poisons

2021
Baclofen: To Screen or Not to Screen in Postmortem Blood?
    Journal of analytical toxicology, 2021, Jul-10, Volume: 45, Issue:6

    Topics: Autopsy; Baclofen; Gabapentin; Humans; Pregabalin; Substance-Related Disorders

2021
Coprescription of Opioids With Other Medications and Risk of Opioid Overdose.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:4

    Topics: Adult; Aged; Analgesics, Opioid; Baclofen; Benzodiazepines; Drug Interactions; Emergency Service, Hospital; Excitatory Amino Acid Antagonists; Female; Gabapentin; Hospitalization; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Muscle Relaxants, Central; Opiate Overdose; Risk Factors

2021
Simultaneous quantitative analysis of 39 common toxicological drugs for increased efficiency in an ante- and postmortem laboratory.
    Forensic science international, 2022, Volume: 334

    Topics: Baclofen; Chromatography, High Pressure Liquid; Forensic Toxicology; Gabapentin; Pregabalin; Reproducibility of Results

2022
Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder.
    JAMA network open, 2022, 05-02, Volume: 5, Issue:5

    Topics: Alcoholism; Baclofen; Female; Gabapentin; Humans; Incidence; Liver Cirrhosis; Male; Middle Aged; Naltrexone; Retrospective Studies; Topiramate

2022
Status Dystonicus with Atypical Presentation in Developmentally Delay Child: A Case Report.
    JNMA; journal of the Nepal Medical Association, 2022, Aug-01, Volume: 60, Issue:252

    Topics: Baclofen; Child; Child, Preschool; Dystonia; Dystonic Disorders; Female; Gabapentin; Humans; Seizures

2022
Treatment of severe tardive dyskinesia with concurrent administration of olanzapine, clonazepam, baclofen, and gabapentin: a case report.
    The Journal of international medical research, 2023, Volume: 51, Issue:10

    Topics: Adolescent; Antipsychotic Agents; Baclofen; Clonazepam; Female; Gabapentin; Humans; Olanzapine; Tardive Dyskinesia

2023