Page last updated: 2024-09-04

fusidic acid and reserpine

fusidic acid has been researched along with reserpine in 8 studies

Compound Research Comparison

Studies
(fusidic acid)
Trials
(fusidic acid)
Recent Studies (post-2010)
(fusidic acid)
Studies
(reserpine)
Trials
(reserpine)
Recent Studies (post-2010) (reserpine)
1,74211734415,546223436

Protein Interaction Comparison

ProteinTaxonomyfusidic acid (IC50)reserpine (IC50)
Bile salt export pumpHomo sapiens (human)8.7875
ATP-dependent translocase ABCB1Homo sapiens (human)3.2092
Quinolone resistance protein NorAStaphylococcus aureus8.5429
Mu-type opioid receptorHomo sapiens (human)4.152
Chromaffin granule amine transporterHomo sapiens (human)0.05
Synaptic vesicular amine transporterRattus norvegicus (Norway rat)0.0034
Synaptic vesicular amine transporterHomo sapiens (human)0.0147

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Elkins, CA; Mullis, LB1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Floyd, JL; Floyd, JT; Kumar, SH; Smith, KP; Varela, MF1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Gustafson, JE; Kaatz, GW; Price, CT1

Reviews

1 review(s) available for fusidic acid and reserpine

ArticleYear
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Other Studies

7 other study(ies) available for fusidic acid and reserpine

ArticleYear
Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Binding, Competitive; Carrier Proteins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Indicators and Reagents; Microbial Sensitivity Tests; Progesterone; Steroids

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Amino Acid Sequence; Bacterial Proteins; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Ethidium; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Onium Compounds; Organophosphorus Compounds; Phylogeny; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Staphylococcus aureus; Trimethoprim; Vancomycin

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The multidrug efflux pump NorA is not required for salicylate-induced reduction in drug accumulation by Staphylococcus aureus.
    International journal of antimicrobial agents, 2002, Volume: 20, Issue:3

    Topics: Bacterial Proteins; Ciprofloxacin; Drug Interactions; Drug Resistance, Bacterial; Ethidium; Fusidic Acid; Multidrug Resistance-Associated Proteins; Mutation; Proton-Motive Force; Reserpine; Sodium Salicylate; Staphylococcus aureus; Time Factors

2002