Page last updated: 2024-09-04

fusidic acid and guanosine diphosphate

fusidic acid has been researched along with guanosine diphosphate in 18 studies

Compound Research Comparison

Studies
(fusidic acid)
Trials
(fusidic acid)
Recent Studies (post-2010)
(fusidic acid)
Studies
(guanosine diphosphate)
Trials
(guanosine diphosphate)
Recent Studies (post-2010) (guanosine diphosphate)
1,7421173444,4852672

Protein Interaction Comparison

ProteinTaxonomyfusidic acid (IC50)guanosine diphosphate (IC50)
72 kDa type IV collagenaseHomo sapiens (human)2.3
MatrilysinHomo sapiens (human)2.3
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6Homo sapiens (human)2.3
Alpha-(1,3)-fucosyltransferase 7Homo sapiens (human)2.3
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1Homo sapiens (human)2.3

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19906 (33.33)18.7374
1990's2 (11.11)18.2507
2000's8 (44.44)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Girbes, T; Modolell, J; Vázquez, D1
Campuzano, S; Girbes, T; Modolell, J; Vźquez, D1
Arai, K; Arai, N; Kaziro, Y; Nakamura, S; Oshima, T1
Campuzano, S; Modolell, J; Vázquez, D1
Legocki, AB1
Chung, HK; Spremulli, LL1
Gongadze, GM; Gudkov, AT1
Fujii, Y; Nakamura, K; Shibata, T; Yamane, K1
Ahuja, D; Joullié, MM; Morimoto, H; SirDeshpande, BV; Toogood, PL; Vera, MD; Williams, PG1
Gudkov, AT; Martemyanov, KA1
Gudkov, AT; Hughes, D; Kristensen, O; Laurberg, M; Liljas, A; Martemyanov, K; Nagaev, I1
Gudkov, AT; Liljas, A; Martemyanov, KA; Yarunin, AS1
Ehrenberg, M; Zavialov, AV1
Gudkov, AT; Hansson, S; Liljas, A; Logan, DT; Singh, R1
Arcari, P; Masullo, M; Palma, M; Raimo, G; Ruggiero, I1
Cooperman, BS; Dempsey, GT; Goldman, YE; Kirillov, SV; Kudaravalli, RD; Pan, D; Qin, H; Wang, Y1
Akita, M; Kuroda, H; Nomura, Y; Nozawa, A; Sattasuk, K; Takabayashi, T; Tozawa, Y; Yukawa, Y1
Gao, YG; Ramakrishnan, V; Selmer, M; Weixlbaumer, A1

Other Studies

18 other study(ies) available for fusidic acid and guanosine diphosphate

ArticleYear
Detection of guanosine-nucleotide.elongation-factor-G complexes produced during the decay of guanosine-nucleotide.elongation-factor-G.Ribosome complexes.
    European journal of biochemistry, 1977, Volume: 81, Issue:3

    Topics: Escherichia coli; Fusidic Acid; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Neomycin; Peptide Elongation Factors; Protein Conformation; Ribosomes; Thiostrepton

1977
Effects of cations, antibiotics and other agents on the turnover of guanosine-nucleotide.elongation-factor-G.ribosome complexes.
    European journal of biochemistry, 1977, Volume: 81, Issue:3

    Topics: Ammonia; Anti-Bacterial Agents; Escherichia coli; Fusidic Acid; Guanine Nucleotides; Guanosine Diphosphate; Kinetics; Magnesium; Peptide Elongation Factors; Ribosomes

1977
Studies on polypeptide-chain-elongation factors from an extreme thermophile, Thermus thermophilus HB8. 2. Catalytic properties.
    European journal of biochemistry, 1978, Volume: 92, Issue:2

    Topics: Escherichia coli; Fusidic Acid; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Peptide Elongation Factors; Protein Binding; Ribosomes; Thermus

1978
Functional interaction of neomycin B and related antibiotics with 30S and 50S ribosomal subunits.
    Biochemical and biophysical research communications, 1979, Apr-13, Volume: 87, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Escherichia coli; Framycetin; Fusidic Acid; Guanosine Diphosphate; Kinetics; Peptide Elongation Factors; Ribosomes; Structure-Activity Relationship

1979
Elongation factor EF-2 from wheat germ: purification and properties.
    Methods in enzymology, 1979, Volume: 60

    Topics: Fusidic Acid; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Methods; Peptide Chain Elongation, Translational; Peptide Elongation Factors; Phenylalanine; Plants; Protein Binding; Ribosomes; Triticum

1979
Purification and characterization of elongation factor G from bovine liver mitochondria.
    The Journal of biological chemistry, 1990, Dec-05, Volume: 265, Issue:34

    Topics: Animals; Cattle; Cell Fractionation; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Fusidic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Male; Mitochondria, Liver; Molecular Weight; Peptide Elongation Factor G; Peptide Elongation Factors; Ribosomes

1990
The L7/L12 proteins change their conformation upon interaction of EF-G with ribosomes.
    FEBS letters, 1984, Oct-15, Volume: 176, Issue:1

    Topics: Bacterial Proteins; Diphosphonates; Escherichia coli; Fusidic Acid; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Peptide Elongation Factor G; Peptide Elongation Factors; Protein Conformation; Ribosomal Proteins; Ribosomes; Trypsin

1984
Depletion of Escherichia coli 4.5S RNA leads to an increase in the amount of protein elongation factor EF-G associated with ribosomes.
    European journal of biochemistry, 1999, Volume: 259, Issue:1-2

    Topics: Bacterial Proteins; Base Sequence; Binding Sites; Binding, Competitive; Centrifugation, Density Gradient; Conserved Sequence; Escherichia coli; Fusidic Acid; Guanosine Diphosphate; Mutation; Nucleic Acid Conformation; Peptide Elongation Factor G; Peptide Elongation Factors; Protein Biosynthesis; Puromycin; Ribosomes; RNA, Bacterial; RNA, Ribosomal, 23S; Signal Recognition Particle; Tetracycline; Viomycin

1999
Inhibition of protein synthesis by didemnin B: how EF-1alpha mediates inhibition of translocation.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Animals; Antineoplastic Agents; Depsipeptides; Diphtheria Toxin; Fusidic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Inhibitory Concentration 50; Models, Biological; Peptide Elongation Factor 1; Peptide Elongation Factor 2; Peptides, Cyclic; Potassium Chloride; Protein Binding; Protein Biosynthesis; Protein Synthesis Inhibitors; Rabbits; Ribosomes; Solutions; Thermodynamics

2000
Domain III of elongation factor G from Thermus thermophilus is essential for induction of GTP hydrolysis on the ribosome.
    The Journal of biological chemistry, 2000, Nov-17, Volume: 275, Issue:46

    Topics: Bacterial Proteins; Fusidic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Models, Molecular; Peptide Elongation Factor G; Protein Biosynthesis; Protein Structure, Tertiary; Puromycin; Ribosomes; Sequence Deletion; Thermus thermophilus

2000
Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site.
    Journal of molecular biology, 2000, Nov-03, Volume: 303, Issue:4

    Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Drug Resistance, Microbial; Fusidic Acid; Guanosine Diphosphate; Models, Molecular; Molecular Sequence Data; Peptide Elongation Factor G; Point Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Thermus thermophilus

2000
Mutations in the G-domain of elongation factor G from Thermus thermophilus affect both its interaction with GTP and fusidic acid.
    The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31

    Topics: Alanine; Aspartic Acid; Binding Sites; Cell-Free System; Fusidic Acid; Genetic Variation; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Peptide Elongation Factor G; Poly U; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Proteins; Thermus thermophilus; Threonine

2001
Peptidyl-tRNA regulates the GTPase activity of translation factors.
    Cell, 2003, Jul-11, Volume: 114, Issue:1

    Topics: Acetylation; Bacteria; Binding Sites; Fusidic Acid; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Models, Biological; Peptide Elongation Factor G; Peptide Elongation Factor Tu; Peptide Termination Factors; Prokaryotic Cells; Prokaryotic Initiation Factor-2; Protein Biosynthesis; Ribosomes; RNA, Transfer; RNA, Transfer, Amino Acyl

2003
Structural insights into fusidic acid resistance and sensitivity in EF-G.
    Journal of molecular biology, 2005, May-13, Volume: 348, Issue:4

    Topics: Crystallography, X-Ray; Drug Resistance, Bacterial; Fusidic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Lysine; Models, Molecular; Mutation; Peptide Elongation Factor G; Protein Structure, Tertiary; Structure-Activity Relationship; Thermus thermophilus

2005
Molecular and functional properties of the psychrophilic elongation factor G from the Antarctic Eubacterium Pseudoalteromonas haloplanktis TAC 125.
    Extremophiles : life under extreme conditions, 2007, Volume: 11, Issue:5

    Topics: Antarctic Regions; Anti-Bacterial Agents; Bacterial Proteins; Cloning, Molecular; Enzyme Stability; Fusidic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Models, Molecular; Molecular Weight; Peptide Elongation Factor G; Protein Biosynthesis; Protein Conformation; Protein Synthesis Inhibitors; Pseudoalteromonas; Recombinant Proteins; Ribosomes; Temperature

2007
Single-molecule structural dynamics of EF-G--ribosome interaction during translocation.
    Biochemistry, 2007, Sep-25, Volume: 46, Issue:38

    Topics: Escherichia coli; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Fusidic Acid; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Models, Molecular; Peptide Elongation Factor G; Peptide Elongation Factor Tu; Protein Biosynthesis; Protein Conformation; Ribosomal Proteins; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer, Phe; Thermodynamics

2007
ppGpp inhibits peptide elongation cycle of chloroplast translation system in vitro.
    Plant molecular biology, 2012, Volume: 78, Issue:1-2

    Topics: Anti-Bacterial Agents; Carbon Radioisotopes; Chloroplasts; Dose-Response Relationship, Drug; Fusidic Acid; Guanosine Diphosphate; Guanosine Tetraphosphate; Guanosine Triphosphate; Leucine; Peptide Chain Elongation, Translational; Peptides; Pisum sativum; Plant Proteins; Poly U; RNA, Messenger; Thiostrepton

2012
Ribosome engineering to promote new crystal forms.
    Acta crystallographica. Section D, Biological crystallography, 2012, Volume: 68, Issue:Pt 5

    Topics: Bacterial Proteins; Crystallography, X-Ray; Fusidic Acid; Guanosine Diphosphate; Homologous Recombination; Models, Molecular; Mutation; Peptide Elongation Factor G; Ribosomal Proteins; Ribosome Subunits, Large, Bacterial; Thermus thermophilus

2012