Compounds > fusidic acid
Page last updated: 2024-09-04

fusidic acid and chlorpromazine

fusidic acid has been researched along with chlorpromazine in 7 studies

Compound Research Comparison

Studies
(fusidic acid)		Trials
(fusidic acid)		Recent Studies (post-2010)
(fusidic acid)		Studies
(chlorpromazine)		Trials
(chlorpromazine)		Recent Studies (post-2010) (chlorpromazine)
1,74211734417,497777739

Protein Interaction Comparison

ProteinTaxonomyfusidic acid (IC50)chlorpromazine (IC50)
Adenylate cyclase type 1 Rattus norvegicus (Norway rat)1.3
Spike glycoproteinBetacoronavirus England 19.51
Replicase polyprotein 1abBetacoronavirus England 19.51
Solute carrier family 22 member 1 Homo sapiens (human)4.3
Transmembrane protease serine 2Homo sapiens (human)9.51
Glutamate receptor ionotropic, NMDA 2DHomo sapiens (human)0.85
Glutamate receptor ionotropic, NMDA 3BHomo sapiens (human)0.85
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)3.4
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.0052
Potassium channel subfamily K member 2Homo sapiens (human)2.7
Tyrosine-protein kinase FynHomo sapiens (human)8.68
Procathepsin LHomo sapiens (human)9.51
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.019
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.652
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.149
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.025
Alpha-2A adrenergic receptorHomo sapiens (human)0.352
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus9.51
Replicase polyprotein 1abHuman coronavirus 229E9.51
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus9.51
Calmodulin-1Homo sapiens (human)7.63
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 29.51
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.083
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)5.8275
D(2) dopamine receptorHomo sapiens (human)0.0142
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.031
Alpha-2B adrenergic receptorHomo sapiens (human)0.026
Alpha-2C adrenergic receptorHomo sapiens (human)0.374
DRattus norvegicus (Norway rat)0.1414
D(3) dopamine receptorRattus norvegicus (Norway rat)0.0416
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4.685
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)1.4791
D(2) dopamine receptorBos taurus (cattle)0.5328
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.206
D(1A) dopamine receptorHomo sapiens (human)0.225
D(4) dopamine receptorHomo sapiens (human)1.365
Adenylate cyclase type 3Rattus norvegicus (Norway rat)1.3
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)1.4791
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)1.4791
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.031
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.019
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)1.4791
Histamine H2 receptorHomo sapiens (human)2.626
Alpha-1D adrenergic receptorHomo sapiens (human)0.004
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.0416
Adenylate cyclase type 2Rattus norvegicus (Norway rat)1.3
Adenylate cyclase type 4Rattus norvegicus (Norway rat)1.3
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0036
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0052
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)4.685
Trypanothione reductaseTrypanosoma cruzi5.8
D(4) dopamine receptorRattus norvegicus (Norway rat)0.0416
Sodium-dependent serotonin transporterHomo sapiens (human)0.0795
Melanocortin receptor 5Homo sapiens (human)7.617
Pleiotropic ABC efflux transporter of multiple drugsSaccharomyces cerevisiae S288C4.5
Histamine H1 receptorHomo sapiens (human)0.0145
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.3
D(3) dopamine receptorHomo sapiens (human)0.012
Sodium channel protein type 1 subunit alphaHomo sapiens (human)4.3
Sodium channel protein type 4 subunit alphaHomo sapiens (human)4.3
Adenylate cyclase type 8Rattus norvegicus (Norway rat)1.3
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.126
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.031
5-hydroxytryptamine receptor 6Homo sapiens (human)0.057
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus9.51
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0365
Calmodulin Bos taurus (cattle)2.5
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)1.3
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)1.3
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)1.3
Sodium channel protein type 7 subunit alphaHomo sapiens (human)4.3
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)3.4
Sodium-dependent dopamine transporter Homo sapiens (human)2.643
Adenylate cyclase type 6Rattus norvegicus (Norway rat)1.3
Adenylate cyclase type 5Rattus norvegicus (Norway rat)1.3
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.85
Aldehyde oxidaseHomo sapiens (human)0.57
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.9602
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.85
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)0.85
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)3.4
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)3.4
Sodium channel protein type 5 subunit alphaHomo sapiens (human)4.3
Glutamate receptor ionotropic, NMDA 2CHomo sapiens (human)0.85
Sodium channel protein type 9 subunit alphaHomo sapiens (human)4.3
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)1.3
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)5.8275
Adenylyl cyclase 7 Rattus norvegicus (Norway rat)1.3
Glutamate receptor ionotropic, NMDA 3AHomo sapiens (human)0.85
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)1.3
DBos taurus (cattle)0.646
Sodium channel protein type 2 subunit alphaHomo sapiens (human)4.3
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.451
Angiotensin-converting enzyme 2 Homo sapiens (human)9.51
Sodium channel protein type 3 subunit alphaHomo sapiens (human)4.3
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)1.3
Sodium channel protein type 11 subunit alphaHomo sapiens (human)4.3
Sodium channel protein type 8 subunit alphaHomo sapiens (human)4.3
Sodium channel protein type 10 subunit alphaHomo sapiens (human)4.3

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Kiriushchenkov, AP; Persianinov, LS; Skosyreva, AM1

Other Studies

7 other study(ies) available for fusidic acid and chlorpromazine

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Cultivation of rat embryos in vitro by New's method in pharmacoembryology].
    Arkhiv anatomii, gistologii i embriologii, 1974, Volume: 66, Issue:4

    Topics: Animals; Chlorpromazine; Culture Techniques; Drug-Related Side Effects and Adverse Reactions; Embryo, Mammalian; Ethanol; Fusidic Acid; Oxacillin; Phenothiazines; Rats; Tetracycline; Vasodilator Agents

1974