fusarin-c and aurofusarin

fusarin-c has been researched along with aurofusarin* in 2 studies

Other Studies

2 other study(ies) available for fusarin-c and aurofusarin

ArticleYear
Influence of carbohydrates on secondary metabolism in Fusarium avenaceum.
    Toxins, 2013, Sep-24, Volume: 5, Issue:9

    Fusarium avenaceum is a widespread pathogen of important crops in the temperate climate zones that can produce many bioactive secondary metabolites, including moniliformin, fusarin C, antibiotic Y, 2-amino-14,16-dimethyloctadecan-3-ol (2-AOD-3-ol), chlamydosporol, aurofusarin and enniatins. Here, we examine the production of these secondary metabolites in response to cultivation on different carbon sources in order to gain insight into the regulation and production of secondary metabolites in F. avenaceum. Seven monosaccharides (arabinose, xylose, fructose, sorbose, galactose, mannose, glucose), five disaccharides (cellobiose, lactose, maltose, sucrose and trehalose) and three polysaccharides (dextrin, inulin and xylan) were used as substrates. Three F. avenaceum strains were used in the experiments. These were all able to grow and produce aurofusarin on the tested carbon sources. Moniliformin and enniatins were produced on all carbon types, except on lactose, which suggest a common conserved regulation mechanism. Differences in the strains was observed for production of fusarin C, 2-AOD-3-ol, chlamydosporol and antibiotic Y, which suggests that carbon source plays a role in the regulation of their biosynthesis.

    Topics: Carbohydrates; Cyclobutanes; Depsipeptides; Ergosterol; Fusarium; Mycotoxins; Naphthoquinones; Polyenes; Pyrones; Secondary Metabolism; Sphingolipids

2013
Functional analysis of the polyketide synthase genes in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum).
    Eukaryotic cell, 2005, Volume: 4, Issue:11

    Polyketides are a class of secondary metabolites that exhibit a vast diversity of form and function. In fungi, these compounds are produced by large, multidomain enzymes classified as type I polyketide synthases (PKSs). In this study we identified and functionally disrupted 15 PKS genes from the genome of the filamentous fungus Gibberella zeae. Five of these genes are responsible for producing the mycotoxins zearalenone, aurofusarin, and fusarin C and the black perithecial pigment. A comprehensive expression analysis of the 15 genes revealed diverse expression patterns during grain colonization, plant colonization, sexual development, and mycelial growth. Expression of one of the PKS genes was not detected under any of 18 conditions tested. This is the first study to genetically characterize a complete set of PKS genes from a single organism.

    Topics: Amino Acid Sequence; Fungal Proteins; Gene Expression Profiling; Gene Expression Regulation, Fungal; Gibberella; Molecular Sequence Data; Naphthoquinones; Pigments, Biological; Polyenes; Polyketide Synthases; Sequence Analysis, DNA; Zearalenone

2005