fusafungin has been researched along with pyranine* in 1 studies
1 other study(ies) available for fusafungin and pyranine
| Article | Year |
|---|---|
Alkali cation transport through liposomes by the antimicrobial fusafungine and its constitutive enniatins.
Fusafungine is a peptide antibiotic mixture composed of several enniatins and active against Gram-positive bacteria. Ionophoric properties of fusafungine have been studied in liposomes by measuring protoncation exchange by both fluorescence and 31P-nuclear magnetic resonance (NMR) and have been compared to those of its constituent enniatin peptides. Fusafungine, as well as enniatins, transport cations through a mobile carrier mechanism selective for K+ vs. Na+ and involving two antibiotic molecules. The transport efficiencies of the various enniatins appear to be related to their hydrophobicity, in agreement with a previously proposed "sandwich" transport model. The ionophoric properties of crude fusafungine may be involved in its antibiotic action and its local therapeutic properties. Topics: Aerosols; Anti-Bacterial Agents; Arylsulfonates; Biological Transport; Cations; Depsipeptides; Fluorescent Dyes; Fusarium; Hydrogen-Ion Concentration; Liposomes; Magnetic Resonance Spectroscopy; Peptides; Phosphates | 1995 |