furosemide has been researched along with verapamil in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (22.97) | 18.7374 |
| 1990's | 10 (13.51) | 18.2507 |
| 2000's | 20 (27.03) | 29.6817 |
| 2010's | 26 (35.14) | 24.3611 |
| 2020's | 1 (1.35) | 2.80 |
| Authors | Studies |
|---|---|
| Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Brockhoff, PB; Christensen, MS; Guldbrandt, M; Jensen, BF; Padkjaer, SB; Refsgaard, HH | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Avdeef, A; Tam, KY | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Akamatsu, M | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| De Matteis, D; Di Michele, M; Fanelli, R; Piemontese, M | 1 |
| Angermann, CE; Dominiak, P; Gerzer, R; Kemkes, BM; Spes, CH; Stempfle, HU; Theisen, K; Weil, J | 1 |
| Deyrup-Olsen, I; Louie, H; Luchtel, DL; Martin, AW | 1 |
| Angermann, CE; Dominiak, P; Kemkes, BM; Spes, CH; Theisen, K; Willems, S | 2 |
| Alon, Y; Elath, U; Eran, M; Freier, S | 1 |
| Hardcastle, J; Hardcastle, PT; Kelleher, DK | 1 |
| Mehmel, HC | 1 |
| Orynchak, MA | 3 |
| Angermann, CE; Anthuber, M; Kemkes, BM; Spes, CH; Theisen, K | 1 |
| Bourgain, RH; Braquet, P; Deby, C; Deby-Dupont, G; Garay, RP; Pincemail, J | 1 |
| Riley, CM | 1 |
| Laszt, A; Modan, M; Oren, S; Viskoper, R | 1 |
| Mzail, AH; Noble, AR | 1 |
| Haas, H | 1 |
| Filias, N; Jornod, J | 1 |
| Angelini, A; Dario, C; Mazzucato, A; Pauletto, P; Pessina, AC; Scannapieco, G; Semplicini, A; Vescovo, G | 1 |
| Bussmann, WD; Grüngras, M; Seher, W | 1 |
| Glänzer, K; Klingmüller, D; Kramer, HJ; Neumark, A; Schmidt, S | 1 |
| Briggs, JP; Greenberg, SG; He, XR; Schnermann, J | 1 |
| Elliott, WJ | 1 |
| Mozhayeva, MG | 1 |
| Lawrenson, JB; Millar, RN; Okreglicki, AM | 1 |
| de Rouffignac, C; Desfleurs, E; Di Stefano, A; Greger, R; Wittner, M | 1 |
| Chiou, WL; Chung, SM; Park, EJ; Swanson, SM; Wu, TC | 1 |
| Panchagnula, R; Varma, MV | 1 |
| Balimane, P; Kadiyala, P; Olah, T; Smalley, J; Xin, B | 1 |
| Carfi', M; Corsini, E; Gennari, A; Gribaldo, L; Hartung, T; Malerba, I; Pallardy, M; Pieters, R; Van Loveren, H; Vohr, HW | 1 |
| Kaukonen, AM; Laitinen, L; Marvola, M; Takala, E; Vuorela, H; Vuorela, P | 1 |
| Hopper, BJ; Irwin, PJ; Nicholls, PK; Olivry, T; Russell, NJ | 1 |
| Jouyban, A; Soltani, S | 1 |
| Anuszewska, E; Krzysztoń-Russjan, J; Lubelska, K; Milczarek, M; Misiewicz-Krzemińska, I; Modzelewska, K; Wiktorska, K | 1 |
| Fronczyk, K; Krzysztoń-Russjan, J; Lubelska, K; Milczarek, M; Modzelewska, K; Wiktorska, K | 1 |
| Gobec, M; Gurwitz, D; Markovič, T; Mlinarič-Raščan, I | 1 |
| Badriddinova, LY; Kondratenko, SN; Kovachevich, IV; Polyakov, AV; Repenkova, LG; Savelyeva, MI; Shikh, EV; Svistunov, AA | 1 |
2 review(s) available for furosemide and verapamil
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for furosemide and verapamil
| Article | Year |
|---|---|
[Reduction in CK- and CKMB-measured infarct size by verapamil].
Topics: Blood Pressure; Creatine Kinase; Dose-Response Relationship, Drug; Furosemide; Heart Block; Heart Rate; Humans; Isoenzymes; Lidocaine; Myocardial Infarction; Nitroglycerin; Verapamil | 1983 |
71 other study(ies) available for furosemide and verapamil
| Article | Year |
|---|---|
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism | 1999 |
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
In silico prediction of membrane permeability from calculated molecular parameters.
Topics: Animals; Cell Line; Cell Membrane Permeability; Diffusion; Dogs; Humans; Intestinal Absorption; Models, Biological; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Verapamil and torsade de pointe (author's transl)].
Topics: Aged; Arrhythmias, Cardiac; Digitalis Glycosides; Electrocardiography; Female; Furosemide; Humans; Hypokalemia; Prenylamine; Tachycardia; Verapamil; Vincamine | 1979 |
Effects of graded exercise on blood pressure, heart rate, and plasma hormones in cardiac transplant recipients before and during antihypertensive therapy.
Topics: Adult; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Drug Therapy, Combination; Enalapril; Epinephrine; Exercise Test; Female; Follow-Up Studies; Furosemide; Heart Rate; Heart Transplantation; Hormones; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Postoperative Complications; Renin; Verapamil | 1992 |
Triggering by ATP of product release by mucous granules of the land slug Ariolimax columbianus.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cytoplasmic Granules; Dinoprostone; Electric Stimulation; Ethylmaleimide; Furosemide; Ibuprofen; Indomethacin; Kinetics; Microscopy, Electron; Mollusca; Mucous Membrane; Nigericin; Pertussis Toxin; Tetradecanoylphorbol Acetate; Verapamil; Virulence Factors, Bordetella | 1992 |
Regression of left ventricular hypertrophy in hypertensive heart transplant recipients treated with enalapril, furosemide, and verapamil.
Topics: Adult; Cardiomegaly; Echocardiography; Electrocardiography; Enalapril; Female; Furosemide; Heart Transplantation; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Verapamil | 1991 |
Verapamil and furosemide prevent cholecystokinin-induced translocation of immunoglobulins in rat intestine.
Topics: Albumins; Animals; Autoantibodies; Biological Transport; Cholecystokinin; Electrolytes; Furosemide; Immunoglobulin A; Immunoglobulin G; In Vitro Techniques; Intestine, Small; Rats; Verapamil | 1991 |
[Circadian behavior of blood pressure and heart rate following orthotopic heart transplantation. Studies before and during antihypertensive therapy].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Enalapril; Female; Furosemide; Heart Rate; Heart Transplantation; Humans; Male; Postoperative Complications; Verapamil | 1989 |
Effect of auranofin on ion transport by rat small intestine.
Topics: Animals; Auranofin; Biological Transport, Active; Body Fluids; Calcium; Electrophysiology; Furosemide; In Vitro Techniques; Intestine, Small; Male; Rats; Sodium-Potassium-Exchanging ATPase; Verapamil | 1989 |
[Therapy of acute myocardial infarct].
Topics: Acidosis; Analgesics; Atropine; Bicarbonates; Bradycardia; Cardiac Complexes, Premature; Critical Care; Diazepam; Digitalis Glycosides; Early Ambulation; First Aid; Furosemide; Heparin; Humans; Hypertension; Lidocaine; Myocardial Infarction; Nitroglycerin; Pacemaker, Artificial; Positive-Pressure Respiration; Sodium; Sodium Bicarbonate; Verapamil | 1985 |
[The efficacy of calcium antagonists in circulatory failure in elderly patients with hypertension].
Topics: Aged; Calcium Channel Blockers; Digoxin; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors; Verapamil | 1989 |
[The use of digoxin, lasix and finoptin in treating circulatory failure in hypertension].
Topics: Aged; Aldosterone; Digoxin; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; Middle Aged; Nucleotides, Cyclic; Potassium; Renin; Sodium; Verapamil | 1989 |
[Effect of digoxin, furosemide and finoptin on the central hemodynamics in hypertension].
Topics: Aged; Chronic Disease; Digoxin; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Verapamil | 1989 |
[Effect of enalapril, furosemide and verapamil on cyclosporin concentration in whole blood].
Topics: Adult; Cyclosporins; Enalapril; Female; Furosemide; Heart Transplantation; Humans; Hypertension; Lung Transplantation; Male; Middle Aged; Prospective Studies; Verapamil | 1988 |
Modulation of in vivo generation of prostanoids by drugs affecting membrane ion transport.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bumetanide; Diuretics; Ethylmaleimide; Furosemide; Insulin; Male; Models, Biological; Potassium; Prostaglandin-Endoperoxide Synthases; Pyridines; Rabbits; Thromboxane B2; Time Factors; Verapamil | 1988 |
Stability of milrinone and digoxin, furosemide, procainamide hydrochloride, propranolol hydrochloride, quinidine gluconate, or verapamil hydrochloride in 5% dextrose injection.
Topics: Digoxin; Drug Combinations; Drug Stability; Drug Storage; Furosemide; Glucose; Indicators and Reagents; Milrinone; Procainamide; Propranolol; Pyridones; Quinidine; Solutions; Temperature; Verapamil | 1988 |
[Hypotensive effect of furosemide and verapamil in the elderly].
Topics: Aged; Blood Pressure; Furosemide; Humans; Hypertension; Middle Aged; Verapamil | 1988 |
Verapamil-induced secretion of active and inactive renin in conscious sheep.
Topics: Animals; Enzyme Precursors; Furosemide; Hemodynamics; Kidney; Kinetics; Renal Circulation; Renin; Sheep; Verapamil | 1986 |
[Effect of verapamil on urinary K-excretion].
Topics: Animals; Diuresis; Dogs; Female; Furosemide; Glomerular Filtration Rate; Kidney; Methyl Ethers; Natriuresis; Plants, Medicinal; Potassium; Potassium Chloride; Rats; Triamterene; Verapamil | 1972 |
[Cardiovascular complications of tricyclic anti-depressants. Apropos of a case of acute poisoning].
Topics: Adult; Arrhythmias, Cardiac; Bundle-Branch Block; Diazepam; Digitalis Glycosides; Electrocardiography; Female; Furosemide; Humans; Imipramine; Poisoning; Respiration; Seizures; Tachycardia; Verapamil | 1973 |
[Evaluation of the efficacy of various hypotensive drugs in broad-breasted white turkeys as an experimental model of arterial hypertension with high catecholamine levels].
Topics: Animals; Antihypertensive Agents; Captopril; Catecholamines; Disease Models, Animal; Furosemide; Hypertension; Labetalol; Male; Oxprenolol; Rats; Turkeys; Verapamil | 1983 |
Renal functional and metabolic studies on the role of preventive measures in experimental acute ischemic renal failure.
Topics: Acute Kidney Injury; Animals; Female; Furosemide; Ischemia; Kidney; Mannitol; Rats; Rats, Inbred Strains; Saralasin; Urodynamics; Verapamil | 1983 |
Effects of furosemide and verapamil on the NaCl dependency of macula densa-mediated renin secretion.
Topics: Animals; Calcium Channels; Female; Furosemide; In Vitro Techniques; Juxtaglomerular Apparatus; Kidney; Kidney Tubules, Distal; Perfusion; Rabbits; Renin; Sodium Chloride; Verapamil | 1995 |
An individualized approach to the hypertensive patient with renal disease: six illustrative case studies.
Topics: Adrenergic alpha-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Arterial Occlusive Diseases; Auscultation; Benzothiadiazines; Cough; Diabetes Mellitus, Type 1; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Minoxidil; Prazosin; Proteinuria; Sodium Chloride Symporter Inhibitors; Verapamil | 1995 |
The inhibitory effects of frusemide on Ca2+ influx pathways associated with oxytocin-induced contractions of rat myometrium.
Topics: Animals; Bucladesine; Calcium; Calcium Channel Blockers; Cyclic AMP; Female; Furosemide; In Vitro Techniques; Intracellular Fluid; Ion Transport; Myometrium; Oxytocin; Rats; Rats, Wistar; Uterine Contraction; Verapamil | 1995 |
Cardiovascular collapse due to intravenous verapamil in two patients with persistent atrial tachycardia.
Topics: Adult; Atenolol; Cardiac Output, Low; Female; Furosemide; Humans; Infusions, Intravenous; Male; Middle Aged; Pregnancy; Tachycardia, Ectopic Atrial; Verapamil | 1995 |
A Ba(2+)-insensitive K+ conductance in the basolateral membrane of rabbit cortical thick ascending limb cells.
Topics: Animals; Apamin; Barium; Cell Membrane; Charybdotoxin; Chloride Channels; Chlorides; Electric Conductivity; Female; Furosemide; In Vitro Techniques; Ion Transport; Loop of Henle; Membrane Potentials; Models, Biological; Nitrobenzoates; Potassium; Potassium Channels; Rabbits; Sodium Chloride; Verapamil | 1998 |
Profound effect of plasma protein binding on the polarized transport of furosemide and verapamil in the Caco-2 model.
Topics: Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Diuretics; Furosemide; Humans; Protein Binding; Verapamil | 2001 |
pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs: kinetic analysis of quinidine efflux in situ.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Chromatography, High Pressure Liquid; Furosemide; Hydrochlorothiazide; Hydrogen-Ion Concentration; Ileum; Intestinal Absorption; Jejunum; Membranes, Artificial; Perfusion; Permeability; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Verapamil | 2005 |
Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples.
Topics: Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Dexamethasone; Etoposide; Furosemide; Humans; Metoprolol; Nadolol; Pharmaceutical Preparations; Propranolol; Quinidine; Rhodamine 123; Spectrometry, Mass, Electrospray Ionization; Sulfasalazine; Verapamil | 2006 |
In vitro tests to evaluate immunotoxicity: a preliminary study.
Topics: Animals; Benzo(a)pyrene; CD3 Complex; Cell Proliferation; Cell Survival; Cyclosporine; Cytokines; Dose-Response Relationship, Drug; Furosemide; Humans; Immunotoxins; Inhibitory Concentration 50; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Phytohemagglutinins; Rats; Reproducibility of Results; Spleen; T-Lymphocytes; Toxicity Tests; Trialkyltin Compounds; Urethane; Verapamil | 2007 |
Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2).
Topics: Absorption; Acetaminophen; Anthraquinones; Beverages; Caco-2 Cells; Carbon Radioisotopes; Cathartics; Cell Membrane Permeability; Digoxin; Furosemide; Humans; Ketoprofen; Mannitol; Plant Leaves; Propranolol; Senna Extract; Sennosides; Verapamil | 2007 |
Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Dog Diseases; Dogs; Fatal Outcome; Female; Furosemide; Hypertension, Pulmonary; Necrosis; Vasculitis; Verapamil | 2008 |
A validated micellar LC method for simultaneous determination of furosemide, metoprolol and verapamil in human plasma.
Topics: Blood Chemical Analysis; Chromatography, Liquid; Furosemide; Humans; Metoprolol; Micelles; Verapamil | 2012 |
Isothiocyanate-drug interactions in the human adenocarcinoma cell line Caco-2.
Topics: Active Transport, Cell Nucleus; Adenocarcinoma; Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Cyclooxygenase Inhibitors; Diuretics; Drug Interactions; Furosemide; Gene Expression; Glutathione Transferase; Humans; Inhibitory Concentration 50; Isothiocyanates; Ketoprofen; Multidrug Resistance-Associated Proteins; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Thiocyanates; Verapamil | 2012 |
Interactions between drugs and sulforaphane modulate the drug metabolism enzymatic system.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Drug Interactions; Furosemide; Glutathione Transferase; Humans; Isothiocyanates; Ketoprofen; Multidrug Resistance-Associated Proteins; NAD(P)H Dehydrogenase (Quinone); Sulfoxides; Thiocyanates; Verapamil | 2012 |
Characterization of human lymphoblastoid cell lines as a novel in vitro test system to predict the immunotoxicity of xenobiotics.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cyclosporine; Furosemide; Humans; Inhibitory Concentration 50; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Interleukin-6; Leukocytes, Mononuclear; Lymphocytes; Mannitol; Toxicity Tests; Trialkyltin Compounds; Tumor Necrosis Factor-alpha; Urethane; Verapamil; Xenobiotics | 2015 |
Study of the pharmacokinetics of various drugs under conditions of antiorthostatic hypokinesia and the pharmacokinetics of acetaminophen under long-term spaceflight conditions.
Topics: Acetaminophen; Furosemide; Humans; Hypokinesia; Pharmaceutical Preparations; Propranolol; Space Flight; Verapamil | 2021 |