furosemide and probenecid

furosemide has been researched along with probenecid in 116 studies

Research

Studies (116)

Timeframe	Studies, this research(%)	All Research%
pre-1990	54 (46.55)	18.7374
1990's	23 (19.83)	18.2507
2000's	20 (17.24)	29.6817
2010's	15 (12.93)	24.3611
2020's	4 (3.45)	2.80

Authors

Authors	Studies
Cragoe, EJ; deSolms, SJ; Fanelli, GM; Watson, LS; Woltersdorf, OW	1
Cragoe, EJ; deSolms, SJ; Woltersdorf, OW	1
Chan, BS; Lu, R; Schuster, VL	1
Cha, SH; Endou, H; Kanai, Y; Kojima, R; Kusuhara, H; Sekine, T; Sugiyama, Y; Tsuda, M; Utsunomiya-Tate, N	1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H	1
Bakos, E; Borst, P; Evers, R; Sarkadi, B; Sinkó, E; Váradi, A	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T	1
Chang, TK; Ensom, MH; Kiang, TK	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Beyer, KH; Bohn, DL; Fanelli, GM; Scriabine, A	1
Buda, E; Pollard, HB; Shulman, NR; Tack-Goldman, K	1
Djawari, D; Ummenhofer, B	1
Bayne, AJ; Hirsch, GH; Pakuts, AP	1
Benet, LZ	1
Brater, DC; Chennavasin, P; Liang, WM; Seiwell, R	1
Brater, DC	1
Bailie, MD; Crosslan, K; Hook, JB	1
Kaplowitz, N; Ryals, P; Wallin, JD	1
Blair, AD; Cutler, RE; Honari, J	1
Branch, RA; Homeida, M; Roberts, C	1
Clifton, G; Kaplowitz, N; Kuhlenkamp, J; Wallin, JD	1
Arslan, Y; Diezi, J; Peters, G; Roch-Ramel, F	1
Bowman, RH	1
Bonet Domingo, E; García Alvarez-Coque, MC; Medina Hernández, MJ; Ramis Ramos, G	1
McCauley, FA; Walshaw, PE; Wilson, TW	1
Rybak, LP; Scott, V; Weberg, A; Whitworth, C	2
Meyer, EC; Moncrieff, J; Sommers, DK	1
Barry, JA; Harig, JM; Ramaswamy, K; Soergel, KH	1
Hirata, Y; Itoh, H; Iwamoto, H; Marumo, F; Shichiri, M	1
Giacomini, KM; Hai, AC; Ott, RJ	1
Böhm, M; Kirch, W; Mönig, H; Ohnhaus, EE	1
Hsieh, BS; Hsieh, YY; Lien, WP; Wu, TL	1
MacDougall, ML; Wiegmann, TB	1
Harnish, PP; Samuel, K	1
Blaine, EH; Heinel, LA; Marsh, EA; Schorn, TW; Whinnery, MA	1
Rybak, LP; Whitworth, C	1
Giacomini, KM; Gisclon, LG; Hsyu, PH; Hui, AC	1
Benet, LZ; Gloff, CA; Mamelok, RD	1
Brasch, H; Iven, H	1
Christensen, S; Petersen, JS	1
Anderson, SA; Brater, DC; Leinfelder, J	1
Hugentobler, G; Meier, PJ; Rahm, I; Valantinas, J	1
Bidiville, J; Roch-Ramel, F	1
Sandström, PE	1
Brater, DC; Krejs, GJ; Valentine, JF	1
Bekersky, I; Popick, AC	1
Denef, J; Ghys, A; Kramp, RA; Lenoir, RH	1
Damm, KH; Woermann, C	1
Bárány, EH	1
Foulkes, EC; Nolan, RP	1
Kürten, M; Vogel, G	1
Cummings, JR; Gussin, RZ; Ronsberg, MA; Stokey, EH	1
Hook, JB; Williamson, HE	1
Forder, JR; Gillis, CN; Pitt, BR	1
Branham, S; Kahn, AM; Weinman, EJ	1
Iwaki, K; Yonetani, Y	1
Brion, N; Carbon, C; Contrepois, A; Cremieux, AC; Dromer, F	1
Green, TP; Juhn, SK; Morizono, T; Rybak, LP	1
Daley-Yates, PT; McBrien, DC	1
Offerhaus, L	1
Brater, DC; Day, B; Kaojarern, S	1
Miwa, T	1
Knight, TF; Sansom, SC; Senekjian, HO; Weinman, EJ	1
Em, SV; Iakovlev, VP; Klimova, VS; Rudzit, EA	1
Bartholomew, TC; Billing, BH; Corbett, CL; Summerfield, JA	1
Beermann, B; Odlind, B	1
Benet, LZ; Brater, DC; Gee, WL; Lin, ET; Smith, DE	1
Horiuchi, K; Itoi, K; Saito, Y; Watanabe, T	1
Andreasen, F; Sigurd, B; Steiness, E	1
van den Biggelaar-Martea, M; Verwey-van Wissen, CP; Vree, TB	2
Gerard, C; Penel, C; Rigot, V	1
Ebisuno, S; Koul, H; Menon, M; Renzulli, L; Scheid, C; Yanagawa, M	1
Hara, A; Komeno, M; Kusakari, J; Machiki, K; Senarita, M	1
Anderson, CC; Bizal, GL; Soleimani, M	1
McCloud, E; Mohammadkhani, R; Said, HM	1
du Souich, P; Pichette, V	1
Battaglia, E; Berg, CL; Drake, RR; Fournel-Gigleux, S; Gollan, JL; Lester, R; Magdalou, J; Mizeracka, M; Nowell, S; Radominska, A	1
Benedetti, A; Di Sario, A; Hofmann, AF; Marucci, L; Schteingart, CD; Svegliati-Baroni, G; Ton-Nu, HT	1
Benet, LZ; Lin, ET; Mizuma, T	1
Burckhardt, BC; Burckhardt, G; Wolff, NA	1
Fujimura, A; Harada, K; Kawaguchi, A; Kitoh, Y; Kobayashi, E; Ohmori, M; Sugimoto , K; Tsuruoka, S	1
Ortiz, A; Said, HM; Vaziri, ND	1
Benet, LZ; Flanagan, SD; Liu, X; Takahashi, LH	1
Hill, MA; Rillema, JA	1
Berryman, E; Chen, C; Franco, J; Hanson, E; Liu, X; Scott, D; Volberg, M	1
Endou, H; Ishikawa, N; Kanai, Y; Kawai, K; Shikano, N	1
Hyde, JE; Sims, PF; Wang, P; Wang, Q	1
Bernardinelli, E; Costa, R; Dossena, S; Nofziger, C; Paulmichl, M	1
Holenarsipur, VK; Kandoussi, H; Mariappan, TT; Shen, H; Sinz, M; Zeng, J; Zhang, Y	1
Britz, H; Fernandez, É; Hanke, N; Lehr, T; Nock, V; Prasad, B; Stopfer, P; Taub, ME; Wang, T	1
Holenarsipur, VK; Humphreys, WG; Lai, Y; Mariappan, TT; Panfen, E; Shen, H; Tang, J; Zhang, Y; Zhao, X; Zheng, J	1
Prasad, B; Saradhi Mettu, V; Singh, DK; Thakur, A	1

Reviews

5 review(s) available for furosemide and probenecid

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug interactions at excretory mechanisms. Pharmacology & therapeutics, 1981, Volume: 15, Issue:1 Topics: Cardiac Glycosides; Drug Interactions; Furosemide; Humans; Hydrogen-Ion Concentration; Kidney Tubules; Lithium; Probenecid; Quinidine; Spironolactone	1981

Trials

3 trial(s) available for furosemide and probenecid

Article	Year
Diuretic and non-diuretic actions of furosemide: effects of probenecid. Clinical and investigative medicine. Medecine clinique et experimentale, 1992, Volume: 15, Issue:1 Topics: Adult; Cyclooxygenase Inhibitors; Drug Interactions; Eicosanoids; Furosemide; Humans; Male; Natriuresis; Probenecid; Renin; Thromboxane B2; Uric Acid	1992
Clinical pharmacology of torasemide, a new loop diuretic. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:2 Topics: Adult; Diuretics; Dose-Response Relationship, Drug; Furosemide; Humans; Kinetics; Male; Nephrons; Probenecid; Random Allocation; Sulfonamides; Torsemide	1987
Probenecid inhibits the renal clearance of frusemide and its acyl glucuronide. British journal of clinical pharmacology, 1995, Volume: 39, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Binding Sites; Cross-Over Studies; Drug Interactions; Female; Furosemide; Glucuronates; Humans; Kidney; Male; Probenecid	1995

Other Studies

108 other study(ies) available for furosemide and probenecid

Article	Year
(Acylaryloxy)acetic acid diuretics. 2. (2-Alkyl-2-aryl-1-oxo-5-indanyloxy)acetic acids. Journal of medicinal chemistry, 1978, Volume: 21, Issue:5 Topics: Acetates; Animals; Chlorides; Diuretics; Dogs; Natriuresis; Pan troglodytes; Potassium; Rats; Stereoisomerism; Structure-Activity Relationship; Uricosuric Agents	1978
(Acylaryloxy)acetic acid diuretics. 4. Indeno[5,4-b]furan-2-carboxylic acids. Journal of medicinal chemistry, 1981, Volume: 24, Issue:7 Topics: Animals; Chemical Phenomena; Chemistry; Diuretics; Indans; Indenes; Pan troglodytes; Rats; Species Specificity; Structure-Activity Relationship; Uricosuric Agents	1981
Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. The American journal of physiology, 1999, Volume: 276, Issue:2 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; DNA, Complementary; HeLa Cells; Humans; Kidney; Molecular Sequence Data; p-Aminohippuric Acid; Protein Kinase C; Rats; Substrate Specificity; Tissue Distribution	1999
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain. The Journal of biological chemistry, 1999, May-07, Volume: 274, Issue:19 Topics: Amino Acid Sequence; Animals; Brain; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Estrone; Molecular Sequence Data; Ochratoxins; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis	1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2 Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism	1999
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions. Molecular pharmacology, 2000, Volume: 57, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anions; Biological Transport; Cell Membrane; Cells, Cultured; DNA-Binding Proteins; Drug Resistance, Multiple; Glutathione; Humans; Insecta; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Molecular pharmacology, 2001, Volume: 59, Issue:5 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Saluretic and uricosuric effects of (6, 7-dichloro-2-methyl=1-oxo-2-phenyl-5-indanyloxy) acetic acid (MK-196) in the chimpanzee. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:2 Topics: Animals; Diuresis; Drug Interactions; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Indans; Indenes; Male; Mersalyl; p-Aminohippuric Acid; Pan troglodytes; Potassium; Probenecid; Rats; Sodium Chloride; Stimulation, Chemical; Time Factors; Uric Acid; Uricosuric Agents	1977
A new class of drugs that inhibit platelet release and aggregation. Transactions of the Association of American Physicians, 1978, Volume: 91 Topics: Anions; Biological Transport; Blood Platelets; Exocytosis; Furosemide; Hydrogen-Ion Concentration; Osmolar Concentration; Platelet Aggregation; Probenecid; Pyridoxal Phosphate; Serotonin; Sulfinpyrazone; Suramin; Thrombin	1978
[Cross allergy between sulphonamide diuretics, probenecid, sulphamethoxazole and sulphonyl-urea compounds (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1979, Apr-06, Volume: 104, Issue:14 Topics: Cross Reactions; Drug Hypersensitivity; Furosemide; Glyburide; Humans; Male; Middle Aged; Probenecid; Skin Tests; Sulfonylurea Compounds	1979
Furosemide accumulation by renal tissue. Biochemical pharmacology, 1975, Nov-01, Volume: 24, Issue:21 Topics: Aminohippuric Acids; Animals; Depression, Chemical; Dinitrophenols; Dogs; Furosemide; In Vitro Techniques; Kidney; Kidney Cortex; Liver; Male; Mice; Niacinamide; Ouabain; Potassium; Probenecid; Rabbits; Rats; Sodium; Time Factors	1975
Pharmacokinetics/pharmacodynamics of furosemide in man: a review. Journal of pharmacokinetics and biopharmaceutics, 1979, Volume: 7, Issue:1 Topics: Biological Availability; Dose-Response Relationship, Drug; Drug Interactions; Furosemide; Heart Failure; Humans; Indomethacin; Kidney Diseases; Kinetics; Probenecid	1979
Pharmacodynamic analysis of the furosemide-probenecid interaction in man. Kidney international, 1979, Volume: 16, Issue:2 Topics: Adult; Dose-Response Relationship, Drug; Drug Interactions; Female; Furosemide; Humans; Kidney; Male; Natriuresis; Premedication; Probenecid	1979
Effects of probenecid on furosemide response. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5 Topics: Adult; Diuresis; Dose-Response Relationship, Drug; Drug Interactions; Female; Furosemide; Humans; Male; Natriuresis; Potassium; Probenecid; Time Factors	1978
Natriuretic effect of furosemide after inhibition of prostaglandin synthetase. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:2 Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Furosemide; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Meclofenamic Acid; Mixed Function Oxygenases; Natriuresis; Probenecid; Prostaglandins E; Regional Blood Flow; Renin; Urination; Vascular Resistance	1976
Metabolic clearance of furosemide in the rat. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1 Topics: Animals; Bile; Chromatography, Thin Layer; Furosemide; Metabolic Clearance Rate; Nephrectomy; Phenobarbital; Probenecid; Rats; Time Factors	1977
Effects of probenecid on furosemide kinetics and natriuresis in man. Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:4 Topics: Drug Interactions; Furosemide; Humans; Infusions, Parenteral; Injections, Intravenous; Kinetics; Male; Natriuresis; Probenecid; Time Factors	1977
Influence of probenecid and spironolactone on furosemide kinetics and dynamics in man. Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:4 Topics: Adult; Drug Interactions; Furosemide; Humans; Kinetics; Male; Natriuresis; Probenecid; Spironolactone; Time Factors	1977
Comparison of renal and hepatic glutathione S-transferases in the rat. The Biochemical journal, 1976, Aug-15, Volume: 158, Issue:2 Topics: Animals; Chromatography, Gel; Furosemide; Glutathione Transferase; Hypophysectomy; Kidney; Kinetics; Liver; Male; p-Aminohippuric Acid; Probenecid; Rats; Thyroxine	1976
[Pharmacologic modifications of renal tubular transport]. Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1976, Volume: 32, Issue:4-6 Topics: Acetazolamide; Biological Transport; Cell Membrane Permeability; Diuretics; Furosemide; Humans; Kidney Tubules; Probenecid; Uric Acid	1976
Renal secretion of [35-S]furosemide and depression by albumin binding. The American journal of physiology, 1975, Volume: 229, Issue:1 Topics: Aminohippuric Acids; Animals; Dose-Response Relationship, Drug; Furosemide; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Kidney Tubules; Kinetics; Male; Probenecid; Rats; Serum Albumin; Sulfur Radioisotopes	1975
High-performance liquid chromatographic determination of diuretics in urine by micellar liquid chromatography. Journal of chromatography, 1992, Nov-06, Volume: 582, Issue:1-2 Topics: Acetazolamide; Bendroflumethiazide; Chlorothiazide; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hydrochlorothiazide; Micelles; Probenecid; Sodium Dodecyl Sulfate	1992
Effects of organic acids on the edema of the stria vascularis induced by furosemide. Hearing research, 1992, Volume: 59, Issue:1 Topics: Acids; Animals; Cochlear Diseases; Edema; Evoked Potentials, Auditory; Furosemide; Microscopy, Electron; Penicillin G; Probenecid; Sodium Salicylate; Stria Vascularis	1992
Effects of organic acids on stria vascularis ultrastructure and function in the chinchilla. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1992, Volume: 249, Issue:3 Topics: Animals; Chinchilla; Cochlear Microphonic Potentials; Edema; Furosemide; Injections, Intravenous; Microscopy, Electron; Penicillin G; Probenecid; Sodium Salicylate; Stria Vascularis	1992
The influence of co-administered organic acids on the kinetics and dynamics of frusemide. British journal of clinical pharmacology, 1991, Volume: 32, Issue:4 Topics: Adult; Drug Interactions; Furosemide; Humans; Male; Probenecid; Pyrazinamide	1991
Transport of propionate by human ileal brush-border membrane vesicles. The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 1 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Adult; Biological Transport; Carboxylic Acids; Chlorides; Female; Furosemide; Harmaline; Humans; Ileum; Intestinal Mucosa; Ions; Kinetics; Male; Microvilli; Probenecid; Propionates; Valinomycin	1991
Renal tubular hypouricemia: evidence for defect of both secretion and reabsorption. Nephron, 1990, Volume: 56, Issue:4 Topics: Aged; Aspirin; Creatinine; Furosemide; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Male; Middle Aged; Probenecid; Pyrazinamide; Uric Acid	1990
Mechanisms of interactions between organic anions and the organic cation transporter in renal brush border membrane vesicles. Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3 Topics: Animals; Anions; Binding, Competitive; Biological Transport; Cations; Furosemide; Kidney; Kinetics; Microvilli; Molecular Structure; Niacinamide; Probenecid; Rabbits	1990
The effects of frusemide and probenecid on the pharmacokinetics of phenprocoumon. European journal of clinical pharmacology, 1990, Volume: 39, Issue:3 Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Drug Interactions; Female; Furosemide; Half-Life; Humans; Male; Phenprocoumon; Probenecid; Prothrombin Time	1990
Probenecid interferes with the natriuretic action of furosemide. Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:5 Topics: Adult; Aged; Diet, Sodium-Restricted; Drug Therapy, Combination; Female; Furosemide; Humans; Kinetics; Male; Middle Aged; Natriuresis; Probenecid; Uric Acid	1987
Urate excretion by the isolated perfused rat kidney and modification by drugs. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 192, Issue:3 Topics: Animals; Furosemide; Glomerular Filtration Rate; Kidney; Natriuresis; Oxonic Acid; Perfusion; Probenecid; Pyrazinamide; Rats; Salicylates; Salicylic Acid; Uric Acid	1989
Pharmacologic manipulation of the flushing action of cerebrospinal fluid. Effect on CSF diatrizoate levels. Investigative radiology, 1988, Volume: 23, Issue:12 Topics: Acetazolamide; Aminophylline; Animals; Bucladesine; Carbachol; Cerebrospinal Fluid; Dexamethasone; Diatrizoate; Digoxin; Furosemide; Male; Premedication; Probenecid; Rats; Rats, Inbred Strains; Ritodrine; Salicylates; Salicylic Acid	1988
The character of the atrial natriuretic response: pressure and volume effects. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1986, Volume: 4, Issue:2 Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Dose-Response Relationship, Drug; Extracellular Space; Female; Furosemide; Hydrochlorothiazide; Macaca mulatta; Male; Natriuresis; Probenecid; Rats; Rats, Inbred Strains; Time Factors	1986
Some organic acids attenuate the effects of furosemide on the endocochlear potential. Hearing research, 1987, Volume: 26, Issue:1 Topics: Animals; Biological Transport; Carboxylic Acids; Chinchilla; Choline; Cochlear Microphonic Potentials; Evoked Potentials, Auditory; Furosemide; Niacinamide; Penicillin G; Probenecid; Salicylates	1987
Interactions of organic anions with the organic cation transporter in renal BBMV. The American journal of physiology, 1988, Volume: 254, Issue:1 Pt 2 Topics: Animals; Biological Transport, Active; Furosemide; Hydrogen-Ion Concentration; Kidney; Kidney Tubules, Proximal; Kinetics; Microvilli; Niacinamide; Probenecid; Rabbits	1988
Organic anion transport by basal-lateral membranes: effect of PAH and furosemide on each other's transport. Pharmacology, 1988, Volume: 37, Issue:4 Topics: Aminohippuric Acids; Animals; Binding, Competitive; Biological Transport, Active; Furosemide; In Vitro Techniques; Kidney; Membranes; p-Aminohippuric Acid; Probenecid; Rabbits; Sulfisoxazole	1988
The effects of antibiotics and uricosuric drugs on the renal elimination of methotrexate and 7-hydroxymethotrexate in rabbits. Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:4 Topics: Animals; Anti-Bacterial Agents; Benzbromarone; Ceftriaxone; Furosemide; Kidney; Metabolic Clearance Rate; Methotrexate; Piperacillin; Probenecid; Rabbits; Sulfamethoxazole; Sulfinpyrazone; Uricosuric Agents	1988
Superiority of tetraethylammonium to p-aminohippurate as a marker for renal plasma flow during furosemide diuresis. Renal physiology, 1987, Volume: 10, Issue:2 Topics: Aminohippuric Acids; Animals; Anions; Diuresis; Female; Furosemide; Kidney; p-Aminohippuric Acid; Probenecid; Rats; Rats, Inbred Strains; Renal Circulation; Tetraethylammonium Compounds	1987
Bicarbonate sulfate exchange in canalicular rat liver plasma membrane vesicles. The American journal of physiology, 1987, Volume: 253, Issue:4 Pt 1 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Animals; Bicarbonates; Biological Transport, Active; Cell Membrane; Furosemide; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Membrane Potentials; Probenecid; Rats; Rats, Inbred Strains; Substrate Specificity; Sulfates; Taurine	1987
Competition of organic anions for furosemide and p-aminohippurate secretion in the rabbit. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2 Topics: Aminohippuric Acids; Animals; Biological Transport; Female; Furosemide; Glomerular Filtration Rate; In Vitro Techniques; Indomethacin; Kidney; Male; Natriuresis; p-Aminohippuric Acid; Probenecid; Pyrazinamide; Rabbits; Time Factors; Tritium	1986
Probenecid potentiates the hyperglycaemic effect but reduces the diuretic effect of frusemide in mice. British journal of pharmacology, 1986, Volume: 89, Issue:2 Topics: Animals; Blood Glucose; Body Weight; Diuretics; Drug Synergism; Female; Furosemide; Glycosuria; Hyperglycemia; Mice; Probenecid	1986
Clearance of furosemide by the gastrointestinal tract. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1 Topics: Adolescent; Adult; Biological Transport; Chlorides; Female; Furosemide; Humans; Intestinal Mucosa; Male; Metabolic Clearance Rate; Probenecid	1986
Disposition of bumetanide in the isolated perfused rat kidney: effects of probenecid and dose response. The American journal of cardiology, 1986, Jan-24, Volume: 57, Issue:2 Topics: Animals; Biological Transport; Bumetanide; Diuresis; Diuretics; Dose-Response Relationship, Drug; Furosemide; Kidney; Kinetics; Male; Perfusion; Probenecid; Rats	1986
Effects of the diuretic torasemide on p-aminohippuric acid transport in the rat. Arzneimittel-Forschung, 1985, Volume: 35, Issue:10 Topics: Aminohippuric Acids; Animals; Biological Transport, Active; Diuretics; Furosemide; Glomerular Filtration Rate; Inulin; Kidney Tubules; Male; Microinjections; p-Aminohippuric Acid; Probenecid; Rats; Rats, Inbred Strains; Sulfonamides; Torsemide	1985
The effect of probenecid on the in vitro absorption of cardiac glycosides. European journal of pharmacology, 1974, Volume: 28, Issue:1 Topics: Animals; Biological Transport; Body Water; Calcium; Cardiac Glycosides; Chromatography, Thin Layer; Digitoxin; Digoxin; Ethacrynic Acid; Furosemide; Glucose; Hydrochlorothiazide; In Vitro Techniques; Intestinal Absorption; Jejunum; Mersalyl; Mice; Mice, Inbred Strains; Osmolar Concentration; Ouabain; Oxygen Consumption; Potassium; Probenecid; Sodium; Tritium	1974
The liver-like anion transport system in rabbit kidney, uvea and choroid plexus. I. Selectivity of some inhibitors, direction of transport, possible physiological substrates. Acta physiologica Scandinavica, 1973, Volume: 88, Issue:3 Topics: Animals; Bile; Biological Transport; Cephaloridine; Choroid Plexus; Depression, Chemical; Ethacrynic Acid; Female; Furosemide; Hippurates; Humans; In Vitro Techniques; Iodipamide; Iodohippuric Acid; Iopanoic Acid; Kidney Cortex; Male; Phenolphthaleins; Probenecid; Rabbits; Uvea	1973
Studies on renal urate secretion in the dog. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:2 Topics: Aminohippuric Acids; Animals; Carbon Isotopes; Chlormerodrin; Chlorothiazide; Dogs; Ethacrynic Acid; Female; Furosemide; Inulin; Kidney; Lactates; Male; Probenecid; Pyrazines; Renal Artery; Time Factors; Tritium; Uric Acid	1971
[Studies on the Na+ -dependency of renal tubular urea secretion in Rana ridibunda]. Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1967, Volume: 295, Issue:1 Topics: Alkaloids; Aminohippuric Acids; Animals; Anura; Biological Transport, Active; Depression, Chemical; Ethacrynic Acid; Furosemide; Glucose; In Vitro Techniques; Kidney Tubules; Organomercury Compounds; Perfusion; Plants, Medicinal; Probenecid; Sodium; Urea	1967
CL 65,562 (4-(a,a,a-trifluoro-m-toluidino)-nicotinic acid), a novel "high ceiling" diuretic. The Journal of pharmacology and experimental therapeutics, 1969, Volume: 167, Issue:1 Topics: Acidosis; Aminohippuric Acids; Animals; Chemical Phenomena; Chemistry; Chlorides; Diuresis; Diuretics; Dogs; Female; Furosemide; Glomerular Filtration Rate; Hydrochlorothiazide; Mannitol; Nicotinic Acids; Potassium; Probenecid; Rats; Sodium; Species Specificity; Water-Electrolyte Balance	1969
Influence of probenecid and alterations in acid-base balance of the saluretic activity of furosemide. The Journal of pharmacology and experimental therapeutics, 1965, Volume: 149, Issue:3 Topics: Acid-Base Equilibrium; Animals; Diuretics; Dogs; Furosemide; Kidney Function Tests; Natriuresis; Probenecid	1965
Drug-induced impairment of pulmonary [3H]prostaglandin E1 removal in vivo. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2 Topics: Alprostadil; Animals; Carbon Radioisotopes; Dextrans; Drug Interactions; Furosemide; Indicator Dilution Techniques; Indocyanine Green; Lung; Male; Probenecid; Prostaglandins E; Rabbits; Tritium	1983
Mechanism of urate and p-aminohippurate transport in rat renal microvillus membrane vesicles. The American journal of physiology, 1983, Volume: 245, Issue:2 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aminohippuric Acids; Animals; Biological Transport; Carbon Radioisotopes; Cell Membrane; Furosemide; Hydrogen-Ion Concentration; Kidney Cortex; Kinetics; Microvilli; p-Aminohippuric Acid; Probenecid; Pyrazinamide; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Tritium; Uric Acid	1983
Decreased renal excretion of uric acid following diuretic administration in rats. Japanese journal of pharmacology, 1984, Volume: 34, Issue:4 Topics: Animals; Diuretics; Furosemide; Insulin; Male; Probenecid; Pyrazinamide; Rats; Rats, Inbred Strains; Trichlormethiazide; Uric Acid	1984
Renal disposition of ceftazidime illustrated by interferences by probenecid, furosemide, and indomethacin in rabbits. Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:3 Topics: Animals; Blood Proteins; Ceftazidime; Diffusion; Drug Interactions; Furosemide; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Probenecid; Protein Binding; Rabbits	1984
Probenecid reduces cochlear effects and perilymph penetration of furosemide in chinchilla. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:3 Topics: Animals; Chinchilla; Chromatography, High Pressure Liquid; Cochlea; Diuresis; Furosemide; Labyrinthine Fluids; Perilymph; Probenecid; Time Factors; Tissue Distribution	1984
The mechanism of renal clearance of cisplatin (cis-dichlorodiammine platinum ii) and its modification by furosemide and probenecid. Biochemical pharmacology, 1982, Jul-01, Volume: 31, Issue:13 Topics: Animals; Cisplatin; Furosemide; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Metabolic Clearance Rate; Probenecid; Rats; Rats, Inbred Strains	1982
The time course of delivery of furosemide into urine: an independent determinant of overall response. Kidney international, 1982, Volume: 22, Issue:1 Topics: Administration, Oral; Binding Sites; Dose-Response Relationship, Drug; Furosemide; Humans; Injections, Intravenous; Kinetics; Natriuresis; Premedication; Probenecid; Time Factors	1982
[Alteration in furosemide metabolism in renal failure rat (author's transl)]. Nihon Jinzo Gakkai shi, 1980, Volume: 22, Issue:8 Topics: Acute Kidney Injury; Animals; Depression, Chemical; Furosemide; Kinetics; Male; Probenecid; Rats	1980
Oxalate secretion in the rat proximal tubule. The American journal of physiology, 1981, Volume: 240, Issue:4 Topics: Animals; Biological Transport, Active; Chloromercuribenzoates; Dose-Response Relationship, Drug; Furosemide; Kidney Tubules, Proximal; Male; Oxalates; p-Aminohippuric Acid; Probenecid; Rats; Sodium Cyanide	1981
[Pharmacokinetic interference between furosemide and cephalosporins]. Antibiotiki, 1981, Volume: 26, Issue:4 Topics: Animals; Cephalosporins; Drug Interactions; Furosemide; Kidney; Kinetics; Probenecid; Rats; Time Factors	1981
Urinary excretion of bile acids in cholestasis: evidence for renal tubular secretion in man. Clinical science (London, England : 1979), 1981, Volume: 61, Issue:6 Topics: Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Ethacrynic Acid; Female; Furosemide; Glycocholic Acid; Humans; Kidney Tubules; Male; Metabolic Clearance Rate; Middle Aged; Probenecid	1981
Renal tubular secretion and effects of furosemide. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:6 Topics: Adult; Blood Proteins; Chlorides; Diuresis; Furosemide; Glomerular Filtration Rate; Humans; Kidney Tubules; Kinetics; Male; Metabolic Clearance Rate; Nephrons; Potassium; Probenecid; Protein Binding; Sodium	1980
Preliminary evaluation of furosemide-probenecid interaction in humans. Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:5 Topics: Adult; Drug Interactions; Furosemide; Humans; Kinetics; Male; Metabolic Clearance Rate; Natriuresis; Probenecid; Prostaglandin Antagonists; Prostaglandins; Time Factors	1980
Mode of action of furosemide on the chloride-dependent short-circuit current across the ciliary body epithelium of toad eyes. The Journal of membrane biology, 1980, Apr-15, Volume: 53, Issue:2 Topics: Animals; Biological Transport; Bufonidae; Chlorides; Ciliary Body; Electrophysiology; Epithelium; Furosemide; Probenecid	1980
Effect of probenecid on excretion and natriuretic action of furosemide. European journal of clinical pharmacology, 1980, Volume: 18, Issue:6 Topics: Blood Proteins; Furosemide; Glomerular Filtration Rate; Humans; Infusions, Parenteral; Inulin; Kidney; Male; Mathematics; Natriuresis; Probenecid	1980
Chloride channel blockers inhibit the Na+/I- symporter in thyroid follicles in culture. Biochemical and biophysical research communications, 1994, Nov-15, Volume: 204, Issue:3 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carrier Proteins; Cells, Cultured; Chloride Channels; Diphenylamine; Furosemide; Hypochlorous Acid; Iodides; Iodine Radioisotopes; Kinetics; Membrane Proteins; Nitrobenzoates; Probenecid; Sodium; Sulfobromophthalein; Swine; Symporters; Thyroid Gland	1994
Determination of furosemide with its acyl glucuronide in human plasma and urine by means of direct gradient high-performance liquid chromatographic analysis with fluorescence detection. Preliminary pharmacokinetics and effect of probenecid. Journal of chromatography. B, Biomedical applications, 1994, Apr-22, Volume: 655, Issue:1 Topics: Chromatography, High Pressure Liquid; Drug Interactions; Furosemide; Humans; Male; Middle Aged; Probenecid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet	1994
Polarized distribution of oxalate transport systems in LLC-PK1 cells, a line of renal epithelial cells. The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anions; Biological Transport; Carboxylic Acids; Cell Line; Cell Membrane; Chlorides; Epithelium; Furosemide; Hydrogen-Ion Concentration; Kidney; Kinetics; Oxalates; Probenecid; Time Factors	1994
Pharmacokinetics of furosemide in endolymph. Auris, nasus, larynx, 1993, Volume: 20, Issue:4 Topics: Animals; Cochlea; Drug Synergism; Endolymph; Furosemide; Guinea Pigs; Probenecid; Tympanic Membrane	1993
A protein with anion exchange properties found in the kidney proximal tubule. Kidney international, 1993, Volume: 44, Issue:3 Topics: Animals; Anion Transport Proteins; Carrier Proteins; Chlorides; Furosemide; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Microvilli; Molecular Weight; Probenecid; Proteolipids; Rabbits; Stilbenes	1993
Mechanism of transport of riboflavin in rabbit intestinal brush border membrane vesicles. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 202, Issue:4 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Folic Acid; Furosemide; Ileum; Intestinal Mucosa; Jejunum; Kinetics; Membrane Potentials; Methotrexate; Microvilli; Organ Specificity; Osmolar Concentration; Potassium; Probenecid; Rabbits; Riboflavin; Valinomycin	1993
Role of the kidneys in the metabolism of furosemide: its inhibition by probenecid. Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:2 Topics: Animals; Furosemide; Hemodynamics; Kidney; Male; Nephrectomy; Probenecid; Rabbits; Reference Values	1996
Two kinetically-distinct components of UDP-glucuronic acid transport in rat liver endoplasmic reticulum. Biochimica et biophysica acta, 1996, Sep-04, Volume: 1283, Issue:2 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Biological Transport; Carrier Proteins; Endoplasmic Reticulum; Furosemide; Kinetics; Liver; Male; Osmolar Concentration; Probenecid; Rats; Rats, Sprague-Dawley; Uridine Diphosphate Glucuronic Acid	1996
Carrier-mediated transport of conjugated bile acids across the basolateral membrane of biliary epithelial cells. The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bile Acids and Salts; Bile Ducts, Intrahepatic; Carrier Proteins; Cell Membrane; Cell Polarity; Chenodeoxycholic Acid; Cholic Acids; Epithelium; Fluorescent Dyes; Furosemide; Glycine; Hydroxysteroid Dehydrogenases; Kinetics; Liver; Male; Membrane Glycoproteins; Probenecid; Rats; Rats, Sprague-Dawley; Sulfobromophthalein	1997
Preparative chromatography of furosemide 1-O-acyl-glucuronide from urine using micronized amberiite XAD-2 and its application to other 1-O-acyl-glucuronides. Preparative biochemistry & biotechnology, 1998, Volume: 28, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Clofibrate; Flufenamic Acid; Furosemide; Glucuronates; Glucuronidase; Indomethacin; Mass Spectrometry; Molecular Structure; Probenecid; Tolmetin	1998
Electrophysiologic characterization of an organic anion transporter cloned from winter flounder kidney (fROAT). Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:1 Topics: Animals; Anion Transport Proteins; Biological Transport, Active; Bumetanide; Carrier Proteins; Cells, Cultured; Clone Cells; Dicarboxylic Acid Transporters; Diuretics; Dose-Response Relationship, Drug; Escherichia coli Proteins; Flounder; Furosemide; Kidney Tubules, Proximal; Membrane Potentials; Membrane Transport Proteins; Oocytes; p-Aminohippuric Acid; Patch-Clamp Techniques; Probenecid; Substrate Specificity; Xenopus laevis	2000
Furosemide-probenecid interaction as a laboratory exercise for undergraduate education in clinical pharmacology. Clinical pharmacology and therapeutics, 2001, Volume: 69, Issue:4 Topics: Diuresis; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Antagonism; Education, Medical, Undergraduate; Furosemide; Humans; Kinetics; Pharmacology, Clinical; Probenecid; Reproducibility of Results; Sodium	2001
Mechanism and regulation of vitamin B(6) uptake by renal tubular epithelia: studies with cultured OK cells. American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:3 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Biological Transport; Calcium; Calmodulin; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dinitrophenols; Diuretics; Enzyme Inhibitors; Epithelial Cells; Extracellular Matrix; Furosemide; Imidazoles; Iodoacetates; Kidney Tubules; Opossums; Probenecid; Pyridoxine; Sodium Azide; Tritium; Uncoupling Agents; Uricosuric Agents	2002
Contributions of saturable active secretion, passive transcellular, and paracellular diffusion to the overall transport of furosemide across adenocarcinoma (Caco-2) cells. Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:4 Topics: Biological Transport, Active; Caco-2 Cells; Diffusion; Diuretics; Dose-Response Relationship, Drug; Furosemide; Humans; Indomethacin; Probenecid	2002
Prolactin regulation of the pendrin-iodide transporter in the mammary gland. American journal of physiology. Endocrinology and metabolism, 2003, Volume: 284, Issue:1 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Blotting, Western; Carrier Proteins; Culture Techniques; Female; Furosemide; Gene Expression Regulation; Iodides; Mammary Glands, Animal; Membrane Transport Proteins; Mice; Pregnancy; Probenecid; Prolactin; Sulfate Transporters	2003
Impact of Mrp2 on the biliary excretion and intestinal absorption of furosemide, probenecid, and methotrexate using Eisai hyperbilirubinemic rats. Pharmaceutical research, 2003, Volume: 20, Issue:1 Topics: Animals; ATP-Binding Cassette Transporters; Biliary Tract; Carrier Proteins; Furosemide; Hyperbilirubinemia; Intestinal Absorption; Male; Methotrexate; Probenecid; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley	2003
Transport of 99mTc-MAG3 via rat renal organic anion transporter 1. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:1 Topics: Animals; Biological Transport, Active; Cells, Cultured; Furosemide; Iodopyracet; Metabolic Clearance Rate; Oocytes; Potassium Channels; Probenecid; Radioisotope Dilution Technique; Radionuclide Imaging; Rats; Recombinant Proteins; Sodium; Technetium Tc 99m Mertiatide; Xenopus laevis	2004
Characterisation of exogenous folate transport in Plasmodium falciparum. Molecular and biochemical parasitology, 2007, Volume: 154, Issue:1 Topics: Animals; Carbohydrate Metabolism; Cell Cycle; Coenzymes; Dinitrophenols; Energy Metabolism; Enzyme Inhibitors; Erythrocytes; Folic Acid; Furosemide; Glycolysis; Humans; Hydrogen-Ion Concentration; Macrolides; Metals; Nigericin; Plasmodium falciparum; Probenecid; Temperature; Uncoupling Agents	2007
Effect of Known Inhibitors of Ion Transport on Pendrin (SLC26A4) Activity in a Human Kidney Cell Line. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 38, Issue:5 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Blotting, Western; Cell Line; Furosemide; HEK293 Cells; Humans; Indoles; Kidney; Membrane Transport Proteins; Niflumic Acid; Nitrobenzoates; Oxindoles; Plasmids; Probenecid; Protein Binding; Spectrometry, Fluorescence; Sulfate Transporters	2016
Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans. Drug metabolism and disposition: the biological fate of chemicals, 2020, Volume: 48, Issue:10 Topics: Administration, Oral; Area Under Curve; Coproporphyrins; Drug Interactions; Female; Furosemide; Healthy Volunteers; HEK293 Cells; Hepatocytes; Humans; Inhibitory Concentration 50; Liver-Specific Organic Anion Transporter 1; Male; Probenecid; Solute Carrier Organic Anion Transporter Family Member 1B3	2020
Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions. Pharmaceutical research, 2020, Nov-25, Volume: 37, Issue:12 Topics: Administration, Intravenous; Administration, Oral; Adult; Biotransformation; Computer Simulation; Drug Elimination Routes; Drug Interactions; Female; Furosemide; Humans; Male; Models, Biological; Organic Anion Transporters; Probenecid; Rifampin	2020
Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition. Drug metabolism and disposition: the biological fate of chemicals, 2021, Volume: 49, Issue:12 Topics: Adjuvants, Pharmaceutic; Biomarkers, Pharmacological; Chromatography, Liquid; Drug Interactions; Furosemide; Healthy Volunteers; Humans; Kynurenic Acid; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Probenecid; Tandem Mass Spectrometry	2021
Effect of probenecid on blood levels and renal elimination of furosemide and endogenous compounds in rats: Discovery of putative organic anion transporter biomarkers. Biochemical pharmacology, 2023, Volume: 218 Topics: Animals; Biomarkers; Drug Interactions; Furosemide; Kidney; Kynurenic Acid; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid; Rats; Renal Elimination	2023