furosemide and pindolol

furosemide has been researched along with pindolol in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.79)18.7374
1990's3 (7.89)18.2507
2000's12 (31.58)29.6817
2010's15 (39.47)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Akamatsu, M1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Goetz, GH; Philippe, L; Shapiro, MJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carney, SL; Doyle, AE; Louis, WJ; Morgan, TO; Roberts, R1
Vetter, H; Werning, C1
Anderson, LA; Barrett, RJ; Proakis, AG; Taylor, DR; Wright, KF1
Achermann, R; Groth, H; Kuhlmann, U; Siegenthaler, W; Vetter, H; Vetter, W1
Seedat, YK1
Werning, C1
Hirsch, DJ; Morgunov, NS; You, YD1
Neuvonen, PJ; Roivas, L1
Kelly, MT; Smyth, MR; Walshe, M1
Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V1
Benzi, JRL; Cavalli, RC; Duarte, G; Gonçalves, PVB; Lanchote, VL; Moreira, FL1

Reviews

3 review(s) available for furosemide and pindolol

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:4

    Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease; Female; Fetal Growth Retardation; Furosemide; Gestational Age; Humans; Hypertension; Incidence; Infant, Small for Gestational Age; Ketanserin; Methyldopa; Network Meta-Analysis; Nifedipine; Perinatal Death; Pindolol; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Severity of Illness Index

2020

Trials

3 trial(s) available for furosemide and pindolol

ArticleYear
Beta-adrenergic receptor blocking drugs, hypertension and plasma renin.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:2

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Furosemide; Humans; Hypertension; Male; Middle Aged; Pindolol; Placebos; Propranolol; Renin

1975
[Diuretics and antihypertensive agents in chronic kidney insufficiency: comparison of the effects of metolazone and furosemide].
    Schweizerische medizinische Wochenschrift, 1985, Jan-12, Volume: 115, Issue:2

    Topics: Adult; Aged; Diuretics; Drug Therapy, Combination; Female; Furosemide; Humans; Hydralazine; Hypertension, Renal; Kidney Failure, Chronic; Male; Metolazone; Middle Aged; Pindolol

1985
Methyldopa combined with prindolol in the treatment of severe hypertension.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Aug-10, Volume: 48, Issue:38

    Topics: Blood Pressure; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension; Male; Methyldopa; Pindolol; Pulse; Urea

1974

Other Studies

32 other study(ies) available for furosemide and pindolol

ArticleYear
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
EPSA: A Novel Supercritical Fluid Chromatography Technique Enabling the Design of Permeable Cyclic Peptides.
    ACS medicinal chemistry letters, 2014, Oct-09, Volume: 5, Issue:10

    Topics:

2014
[Effect of pindolol (Visken) on blood pressure and plasma renin activity in various forms of hypertension].
    Advances in clinical pharmacology, 1976, Volume: 11

    Topics: Adult; Aged; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Pindolol; Renin; Rest; Time Factors

1976
Effect of bopindolol on renin secretion and renal excretory function in rats.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Electrolytes; Furosemide; Male; Pindolol; Rats; Rats, Inbred Strains; Renin; Urination

1989
[Lowering of the blood pressure and renin suppression by beta receptor blockade with Visken in patients with borderline hypertension (author's transl)].
    Medizinische Klinik, 1973, Nov-23, Volume: 68, Issue:47

    Topics: Adult; Blood Pressure; Female; Furosemide; Humans; Hypertension; Male; Natriuresis; Pindolol; Renin

1973
Response of mouse proximal straight tubule and medullary thick ascending limb to beta-agonist.
    Journal of the American Society of Nephrology : JASN, 1993, Volume: 4, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Electrophysiology; Furosemide; In Vitro Techniques; Isoproterenol; Kidney Medulla; Kidney Tubules; Kidney Tubules, Proximal; Kinetics; Membrane Potentials; Mice; Perfusion; Pindolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta

1993
Drug adsorption onto activated charcoal as a means of formulation.
    Methods and findings in experimental and clinical pharmacology, 1994, Volume: 16, Issue:5

    Topics: Adsorption; Albuterol; Charcoal; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Clonidine; Furosemide; Kinetics; Metoprolol; Pindolol; Sympatholytics

1994
Comparison of two extraction methods for determination of propranolol and furosemide in human plasma by mixed-mode chromatography.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:4

    Topics: Adrenergic beta-Antagonists; Chromatography; Diuretics; Furosemide; Humans; Pindolol; Propranolol

1996
Nonrelevant Pharmacokinetic Drug-Drug Interaction Between Furosemide and Pindolol Enantiomers in Hypertensive Parturient Women.
    Journal of clinical pharmacology, 2020, Volume: 60, Issue:11

    Topics: Administration, Oral; Antihypertensive Agents; Diuretics; Drug Interactions; Female; Furosemide; Humans; Hypertension; Parturition; Pindolol; Pregnancy; Pregnancy Complications; Stereoisomerism

2020