furosemide and kanamycin a

furosemide has been researched along with kanamycin a in 78 studies

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (32.05)	18.7374
1990's	4 (5.13)	18.2507
2000's	9 (11.54)	29.6817
2010's	34 (43.59)	24.3611
2020's	6 (7.69)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Iaroshevich, VI	1
Hybels, RL	1
Laitakari, K	1
Ohtani, I; Ohtsuki, K; Omata, T; Ouchi, J; Saito, T	2
Asakuma, S; Lowry, LD; Snow, JB	1
Nakai, Y	1
Aranda, JV; Cohen, S; Neims, AH	1
Dunn, E; Kirsh, MM; Lee, R; Nishiyama, R; Prager, R; Sloan, H; Straker, J	1
Pedersen, CB; Sorensen, H	1
Ono, T; Tachibana, M	1
Konishi, K; Nakai, Y; Yamane, H	1
Allen, LV; Desai, SR; Rao, PS; Thompson, DF	1
Rybak, LP	1
Bigos, T; Crossley, K; Joffe, CD	1
Bewick, M; Brown, CB; Cameron, JS; Ogg, CS	1
Falk, SA	1
Gavras, H; Hartz, S; Lawson, DH; Linton, AL; Macadam, RF; Singh, MH; Turnbull, D	1
D'Arcy, PF; Harpur, ES	1
Humes, LE	1
Minowa, Y	1
Bleeker, JD; Wit, HP	1
Hata, T; Sakamoto, K; Suzuki, H; Takeda, U; Yokota, M	1
Lietman, PS; Smith, CR	1
Komune, S; Snow, JB	1
Mirahmadi, MK; Vaziri, ND	1
Garraghty, PE; Kaas, JH; Schwaber, MK	1
Butterfield, DA; Clerici, WJ; DiMartino, DL; Hensley, K	1
Alam, SA; Ikeda, K; Katori, Y; Kawase, T; Kikuchi, T; Takasaka, T; Watanabe, K	1
Clark, G; Hardman, J; O'leary, S; Richardson, R; Wise, AK	1
Agterberg, MJ; de Groot, JC; Klis, SF; Smoorenburg, GF; Versnel, H	1
Campbell, S; Forge, A; Hume, CR; Oesterle, EC; Taylor, RR	1
Agterberg, MJ; Albers, FW; de Groot, JC; Klis, SF; Smoorenburg, GF; Versnel, H	1
Agterberg, MJ; de Groot, JC; Klis, SF; van Dijk, LM; Versnel, H	1
Basak, O; Bermingham-McDonogh, O; Hartman, BH; Nelson, BR; Reh, TA; Taylor, V	1
Campbell, S; Oesterle, EC	1
Camarero, G; García-Alcántara, F; Murillo-Cuesta, S; Rivera, T; Sistiaga, JA; Vacas, E; Varela-Nieto, I	1
Chen, J; Chen, QG; Chu, HQ; Cui, YH; Huang, XW; Li, JL; Li, ZY; Wang, Y; Xiong, H; Zhou, LQ	1
Agterberg, MJ; de Groot, JC; Grolman, W; Havenith, S; Klis, SF; Sedee, RJ; Versnel, H	1
Grolman, W; Klis, SF; Prijs, VF; Stronks, HC; Versnel, H	1
Hirose, K; Sato, E	1
Chen, J; Chen, Q; Chu, H; Cui, Y; Huang, X; Li, J; Li, Z; Wang, Y; Xiong, H; Zhou, L; Zhou, X	1
Chen, X; Huang, G; Jiang, H	1
Bremer, HG; de Groot, JC; Klis, SF; Versnel, H	1
Chimona, TS; Grolman, W; Klis, SF; Prijs, VF; Stronks, HC	1
Agterberg, MJ; de Groot, JC; Grolman, W; Klis, SF; Ramekers, D; van Loon, MC; Versnel, H	1
Grolman, W; Hendriksen, FG; Klis, SF; Ramekers, D; Van Deurzen, MH; Waaijer, L	1
Brough, DE; Hsu, C; Kraft, S; Staecker, H	1
Bremer, HG; Grolman, W; Hendriksen, FG; Jansen, TT; Klis, SF; Topsakal, V	1
Grolman, W; Havenith, S; Klis, SF; Versnel, H	2
Gao, J; Guo, WW; Han, DY; Li, Z; Sun, AL; Sun, DX; Sun, JH; Wei, XN; Yang, SM; Zhang, XF	1
Johnson, SB; Santi, PA; Schmitz, HM	1
Fernandes, VT; Lin, VY	1
Hirose, K; Li, SZ; Ohlemiller, KK; Ransohoff, RM	1
Grolman, W; Klis, SF; Ramekers, D; Strahl, SB; Versnel, H	1
Hu, H; Nie, C; Shen, C; Wu, H; Xiang, M; Ye, B	1
Chen, Y; Qiao, L; Qiu, J; Wang, Y; Wen, L; Wu, S; Yue, B	1
Bezdjian, A; Grolman, W; Hendriksen, FG; Klis, SF; van der Linden, CA; Żak, M	1
Kaur, T; Ohlemiller, KK; Warchol, ME	1
Bermúdez-Muñoz, JM; García-Alcántara, F; Martínez-Vega, R; Milo, M; Murillo-Cuesta, S; Pulido, S; Rivera, T; Varela-Nieto, I	1
Qiu, J; Qiu, Y; Song, Y; Sun, F; Tian, K; Wang, R; Yue, B; Zha, D; Zhou, K	1
Deng, X; Hu, Z; Li, X; Liu, Z; Zhou, Y	1
Chen, F; Chen, J; Li, W; Liu, Z; Mi, W; Qiu, J; Wang, R; Xing, W; Yan, H; Zha, D	1
Klis, SFL; Ramekers, D; Versnel, H	1
Deng, X; Hu, Z	1
Fan, C; Hu, H; Shen, Y; Wang, Q; Xiang, M; Ye, B; Zou, T	1
Bako, P; Gerlinger, I; Löwenheim, H; Müller, M; Wolpert, S	1
Ahrens, D; Bankstahl, JP; Behrends, W; Esser, KH; Lenarz, T; Paasche, G; Scheper, V	1
Li, C; Yang, C; Yang, J; Yi, J	1

Reviews

1 review(s) available for furosemide and kanamycin a

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for furosemide and kanamycin a

Article	Year
High dose frusemide in acute reversible intrinsic renal failure. A preliminary communication. Scottish medical journal, 1974, Volume: 19 Suppl 1 Topics: Acute Kidney Injury; Adult; Clinical Trials as Topic; Deafness; Furosemide; Gentamicins; Humans; Kanamycin; Male; Middle Aged; Oliguria; Peritoneal Dialysis; Renal Dialysis	1974
Effect of furosemide on aminoglycoside-induced nephrotoxicity and auditory toxicity in humans. Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1 Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Interactions; Ear; Ethacrynic Acid; Furosemide; Humans; Kanamycin; Kidney; Middle Aged	1983

Other Studies

75 other study(ies) available for furosemide and kanamycin a

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[Ototoxicity of some drug agents]. Voenno-meditsinskii zhurnal, 1975, Issue:10 Topics: Age Factors; Aminoglycosides; Bleomycin; Cochlea; Deafness; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ear; Ethacrynic Acid; Furosemide; Hearing Disorders; Humans; Kanamycin; Neomycin; Streptomycin; Toxicology; Vestibule, Labyrinth; Viomycin	1975
Drug toxicity of the inner ear. The Medical clinics of North America, 1979, Volume: 63, Issue:2 Topics: Animals; Chloroquine; Dihydrostreptomycin Sulfate; Ethacrynic Acid; Furosemide; Gentamicins; Humans; Kanamycin; Labyrinth Diseases; Neomycin; Quinine; Salicylates; Streptomycin; Tobramycin	1979
Vestibular disorders in medically managed chronic renal insufficiency. Acta oto-laryngologica. Supplementum, 1977, Volume: 349 Topics: Adolescent; Adult; Aged; Audiometry; Caloric Tests; Deafness; Ear; Electronystagmography; Female; Furosemide; Hearing Disorders; Humans; Kanamycin; Kidney Failure, Chronic; Labyrinth Diseases; Male; Middle Aged; Streptomycin; Vestibular Function Tests; Vestibule, Labyrinth	1977
Potentiation and its mechanism of cochlear damage resulting from furosemide and aminoglycoside antibiotics. ORL; journal for oto-rhino-laryngology and its related specialties, 1978, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Body Fluids; Body Weight; Cochlea; Drug Synergism; Furosemide; Gentamicins; Kanamycin; Kidney; Rabbits; Streptomycin	1978
Endocochlear DC potential in kanamycin-sulfate-treated guinea pigs. Surgical forum, 1977, Volume: 28 Topics: Action Potentials; Animals; Cochlea; Furosemide; Guinea Pigs; Hypoxia; Kanamycin	1977
[Interaction of bumetanide and kanamycin (author's transl)]. Nihon Jibiinkoka Gakkai kaiho, 1978, Jun-20, Volume: 81, Issue:6 Topics: Animals; Bumetanide; Diuretics; Drug Interactions; Ear Diseases; Ear, Middle; Furosemide; Hair Cells, Auditory; Kanamycin; Kidney Tubules, Proximal; Rabbits	1978
Combined effect of 3', 4'-dideoxykanamycin B and potent diuretics on the cochlea. (A scanning and transmission electron microscopic evaluation). The Laryngoscope, 1977, Volume: 87, Issue:9 Pt 1 Topics: Animals; Cochlea; Dibekacin; Drug Synergism; Ethacrynic Acid; Furosemide; Guinea Pigs; Hair Cells, Auditory; Hearing Disorders; Kanamycin; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Mitochondria; Organ of Corti	1977
Drug utilization in a newborn intensive care unit. The Journal of pediatrics, 1976, Volume: 89, Issue:2 Topics: Ampicillin; Bicarbonates; Birth Weight; Canada; Chloramphenicol; Drug Therapy, Combination; Drug Utilization; Female; Furosemide; Gentamicins; Gestational Age; Gluconates; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intensive Care Units; Kanamycin; Male; Penicillin G	1976
The benefits of corticosteroids in endotoxic shock. The Annals of thoracic surgery, 1975, Volume: 19, Issue:2 Topics: Animals; Assisted Circulation; Cardiac Output; Cardiopulmonary Bypass; Dogs; Escherichia coli; Furosemide; Glucocorticoids; Hemodynamics; Hypothermia, Induced; Kanamycin; Lung; Mesenteric Vascular Occlusion; Methylprednisolone; Myocardium; Shock, Septic; Time Factors; Water-Electrolyte Balance	1975
[Scanning electron microscopy of the inner ear as a screening test for ototoxicity]. Ugeskrift for laeger, 1975, Oct-20, Volume: 137, Issue:43 Topics: Animals; Cochlea; Ear, Inner; Furosemide; Guinea Pigs; Kanamycin; Mass Screening; Microscopy, Electron, Scanning	1975
Origin of the endolymphatic DC potential in the cochlea and ampulla of the guinea pig. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1990, Volume: 248, Issue:2 Topics: Action Potentials; Animals; Cell Hypoxia; Cochlea; Endolymph; Furosemide; Guinea Pigs; Kanamycin; Semicircular Canals; Streptomycin	1990
Furosemide-induced alteration of drug pathway to cochlea. Acta oto-laryngologica. Supplementum, 1988, Volume: 447 Topics: Animals; Cochlea; Drug Synergism; Fluorescent Antibody Technique; Furosemide; Guinea Pigs; Kanamycin; Organ of Corti; Time Factors	1988
Compatibility of furosemide with aminoglycoside admixtures. American journal of hospital pharmacy, 1985, Volume: 42, Issue:1 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Chemical Phenomena; Chemistry, Physical; Drug Combinations; Drug Incompatibility; Furosemide; Gentamicins; Hydrogen-Ion Concentration; Kanamycin; Netilmicin; Tobramycin	1985
Furosemide ototoxicity: clinical and experimental aspects. The Laryngoscope, 1985, Volume: 95, Issue:9 Pt 2 Sup Topics: Animals; Cats; Chinchilla; Cochlea; Cochlear Duct; Cochlear Microphonic Potentials; Dose-Response Relationship, Drug; Drug Synergism; Endolymph; Female; Furosemide; Guinea Pigs; Hair Cells, Auditory; Humans; Kanamycin; Male; Potassium; Rats; Vestibulocochlear Nerve	1985
Hemophilus influenzae pericarditis. A report of two cases in adults with a summary of the literature. American heart journal, 1973, Volume: 85, Issue:2 Topics: Adult; Ampicillin; Child; Child, Preschool; Chloramphenicol; Female; Furosemide; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Infant, Newborn; Kanamycin; Male; Pericarditis; Streptomycin	1973
Combined effects of noise and ototoxic drugs. Environmental health perspectives, 1972, Volume: 2 Topics: Animals; Anti-Bacterial Agents; Cochlea; Diuretics; Environmental Exposure; Ethacrynic Acid; Furosemide; Guinea Pigs; Haplorhini; Hearing Disorders; Humans; Kanamycin; Microscopy, Electron; Neomycin; Noise; Occupational Diseases; Organ of Corti; Quinine; Salicylates; Sound; Streptomycin	1972
Effect of furosemide on antibiotic-induced renal damage in rats. The Journal of infectious diseases, 1972, Volume: 126, Issue:6 Topics: Animals; Anti-Bacterial Agents; Cephaloridine; Cephalothin; Colistin; Female; Furosemide; Glycerol; Kanamycin; Kidney; Kidney Tubules, Proximal; Necrosis; Organ Size; Rats; Time Factors; Urea	1972
Laboratory testing for ototoxic effects of drugs. British journal of pharmacology, 1973, Volume: 48, Issue:2 Topics: Animals; Ear Diseases; Ethacrynic Acid; Furosemide; Hearing Disorders; Hearing Tests; Kanamycin; Mice; Mice, Inbred Strains; Reflex, Startle; Toxicology	1973
Noise-induced hearing loss as influenced by other agents and by some physical characteristics of the individual. The Journal of the Acoustical Society of America, 1984, Volume: 76, Issue:5 Topics: Acoustic Stimulation; Age Factors; Animals; Ethacrynic Acid; Eye Color; Furosemide; Hearing Loss, Noise-Induced; Hearing Loss, Sensorineural; Humans; Kanamycin; Melanins; Neomycin; Presbycusis; Risk; Salicylates; Vibration	1984
[Sensorineural hearing impairment by combined administration of aminoglycoside drugs, loop diuretics and an anticancer drug (cisplatin)--an experimental study]. Nihon Jibiinkoka Gakkai kaiho, 1984, Volume: 87, Issue:2 Topics: Animals; Cisplatin; Drug Therapy, Combination; Furosemide; Guinea Pigs; Hearing Loss, Sensorineural; Kanamycin; Organ of Corti	1984
A possible method to study transient effects of ototoxic agents on the vestibular system. Archives of oto-rhino-laryngology, 1983, Volume: 238, Issue:2 Topics: Animals; Cochlear Nerve; Columbidae; Ethacrynic Acid; Evoked Potentials, Auditory; Furosemide; Kanamycin; Vestibular Nerve; Vestibule, Labyrinth	1983
[Ocular and auditory organs of Ochotona rufescens]. Jikken dobutsu. Experimental animals, 1983, Volume: 32, Issue:4 Topics: Animals; Animals, Laboratory; Atropine; Dogs; Ear, Inner; Electroretinography; Furosemide; Guinea Pigs; Kanamycin; Lagomorpha; Mammals; Pilocarpine; Pupil; Rats; Rats, Inbred Strains; Reflex, Acoustic; Retina	1983
Nature of the endocochlear dc potential in kanamycin-poisoned guinea pigs. Archives of otolaryngology (Chicago, Ill. : 1960), 1982, Volume: 108, Issue:6 Topics: Animals; Cochlea; Cochlear Duct; Evoked Potentials, Auditory; Furosemide; Guinea Pigs; Infusions, Parenteral; Kanamycin; Perfusion; Scala Tympani; Stria Vascularis	1982
Hearing loss in end-stage renal disease - effect of dialysis. Journal of dialysis, 1980, Volume: 4, Issue:4 Topics: Furosemide; Gentamicins; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Male; Renal Dialysis; Vancomycin	1980
Neuroplasticity of the adult primate auditory cortex following cochlear hearing loss. The American journal of otology, 1993, Volume: 14, Issue:3 Topics: Animals; Audiometry, Pure-Tone; Auditory Cortex; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Female; Furosemide; Hearing Loss, Sensorineural; Kanamycin; Macaca mulatta	1993
Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants. Hearing research, 1996, Sep-01, Volume: 98, Issue:1-2 Topics: Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Cochlea; Cyclic N-Oxides; Diuretics; Electron Spin Resonance Spectroscopy; Ethacrynic Acid; Female; Furosemide; Gentamicins; Guinea Pigs; Hydrogen Peroxide; Hydroxyl Radical; Kanamycin; Male; Perilymph; Quinine; Spin Labels; Trimethyltin Compounds	1996
Acute effects of combined administration of kanamycin and furosemide on the stria vascularis studied by distortion product otoacoustic emission and transmission electron microscopy. The Tohoku journal of experimental medicine, 1998, Volume: 186, Issue:2 Topics: Animals; Anti-Bacterial Agents; Diuretics; Drug Synergism; Furosemide; Guinea Pigs; Hearing Loss; Kanamycin; Microscopy, Electron; Otoacoustic Emissions, Spontaneous; Stria Vascularis	1998
Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3. The Journal of comparative neurology, 2005, Jun-27, Volume: 487, Issue:2 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Count; Cell Survival; Cochlea; Cochlear Implantation; Deafness; Disease Models, Animal; Furosemide; GAP-43 Protein; Guinea Pigs; Immunohistochemistry; Kanamycin; Models, Biological; Nerve Degeneration; Nerve Regeneration; Neurofilament Proteins; Neurons, Afferent; Neurotrophin 3; Time Factors	2005
Time course of cochlear electrophysiology and morphology after combined administration of kanamycin and furosemide. Hearing research, 2007, Volume: 231, Issue:1-2 Topics: Action Potentials; Animals; Anti-Bacterial Agents; Cell Survival; Cochlea; Deafness; Electrophysiology; Female; Furosemide; Ganglia; Ganglia, Spinal; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Sodium Potassium Chloride Symporter Inhibitors	2007
Sox2 and JAGGED1 expression in normal and drug-damaged adult mouse inner ear. Journal of the Association for Research in Otolaryngology : JARO, 2008, Volume: 9, Issue:1 Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Biomarkers; Calcium-Binding Proteins; Chickens; Cochlear Diseases; Disease Models, Animal; Diuretics; Furosemide; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Kanamycin; Membrane Proteins; Mice; Mice, Inbred CBA; Organ of Corti; Serrate-Jagged Proteins; SOXB1 Transcription Factors; Time Factors	2008
Morphological changes in spiral ganglion cells after intracochlear application of brain-derived neurotrophic factor in deafened guinea pigs. Hearing research, 2008, Volume: 244, Issue:1-2 Topics: Animals; Brain-Derived Neurotrophic Factor; Cochlea; Electrons; Female; Furosemide; Guinea Pigs; Kanamycin; Microscopy, Electron; Mitochondria; Myelin Sheath; Neurons; Spiral Ganglion	2008
Enhanced survival of spiral ganglion cells after cessation of treatment with brain-derived neurotrophic factor in deafened guinea pigs. Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:3 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cochlear Implants; Deafness; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Female; Furosemide; Guinea Pigs; Kanamycin; Models, Animal; Nerve Degeneration; Protein Synthesis Inhibitors; Sodium Potassium Chloride Symporter Inhibitors; Spiral Ganglion	2009
Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea. Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:3 Topics: Aging; Animals; Basic Helix-Loop-Helix Transcription Factors; Cochlea; Ear, Inner; Epithelium; Furosemide; Green Fluorescent Proteins; Kanamycin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Protein Synthesis Inhibitors; Receptors, Notch; Regeneration; Repressor Proteins; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors	2009
Supporting cell characteristics in long-deafened aged mouse ears. Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:4 Topics: Aging; Animals; Biomarkers; Calcium-Binding Proteins; Cell Differentiation; Deafness; Diuretics; Furosemide; Hair Cells, Auditory; Humans; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Kanamycin; Labyrinth Supporting Cells; Membrane Proteins; Mice; Protein Synthesis Inhibitors; Serrate-Jagged Proteins; SOXB1 Transcription Factors; Spiral Ganglion; Tubulin	2009
Direct drug application to the round window: a comparative study of ototoxicity in rats. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2009, Volume: 141, Issue:5 Topics: Administration, Topical; Animals; Cochlea; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hearing Loss; Injections, Intravenous; Injections, Subcutaneous; Kanamycin; Male; Random Allocation; Rats; Rats, Wistar; Round Window, Ear	2009
[Rapid cochlea lesion induced by co-administration of kanamycin and furosemide in mouse]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2010, Volume: 45, Issue:3 Topics: Animals; Cell Death; Cochlea; Disease Models, Animal; Drug Synergism; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory; Kanamycin; Mice; Mice, Inbred CBA	2010
Spiral ganglion cell survival after round window membrane application of brain-derived neurotrophic factor using gelfoam as carrier. Hearing research, 2011, Volume: 272, Issue:1-2 Topics: Acoustic Stimulation; Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Shape; Cell Size; Cell Survival; Disease Models, Animal; Drug Carriers; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Female; Furosemide; Gelatin Sponge, Absorbable; Guinea Pigs; Hearing Loss; Kanamycin; Neuroprotective Agents; Spiral Ganglion; Time Factors	2011
Effects of electrical stimulation on the acoustically evoked auditory-nerve response in guinea pigs with a high-frequency hearing loss. Hearing research, 2011, Volume: 272, Issue:1-2 Topics: Acoustic Stimulation; Animals; Auditory Threshold; Cochlea; Cochlear Implantation; Cochlear Microphonic Potentials; Cochlear Nerve; Disease Models, Animal; Female; Furosemide; Guinea Pigs; Hearing Loss, High-Frequency; Kanamycin; Time Factors	2011
Comparative analysis of combination kanamycin-furosemide versus kanamycin alone in the mouse cochlea. Hearing research, 2011, Volume: 272, Issue:1-2 Topics: Acoustic Stimulation; Animals; Atrophy; Auditory Threshold; Cell Death; Cell Movement; Cochlea; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory, Outer; Hearing Loss; Kanamycin; Macrophages; Male; Mice; Mice, Inbred C57BL; Monocytes	2011
Conservation of endocochlear potential in mice with profound hearing loss induced by co-administration of kanamycin and furosemide. Laboratory animals, 2011, Volume: 45, Issue:2 Topics: Animals; Anti-Bacterial Agents; Auditory Threshold; Cell Death; Cell Survival; Cochlea; Cochlear Microphonic Potentials; Disease Models, Animal; Diuretics; Drug Combinations; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Hearing Loss; Kanamycin; Male; Mice; Mice, Inbred CBA; Protein Synthesis Inhibitors; Stria Vascularis; Time Factors	2011
Effects of NasoPore packing in the middle ear cavity of the guinea pig. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2011, Volume: 145, Issue:1 Topics: Animals; Anti-Bacterial Agents; Auditory Threshold; Cell Count; Diuretics; Ear, Inner; Ear, Middle; Evoked Potentials, Auditory, Brain Stem; Foreign-Body Reaction; Furosemide; Gelatin Sponge, Absorbable; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Microscopy, Electron, Scanning; Polyurethanes; Tampons, Surgical	2011
Combined administration of kanamycin and furosemide does not result in loss of vestibular function in Guinea pigs. Audiology & neuro-otology, 2012, Volume: 17, Issue:1 Topics: Animals; Anti-Bacterial Agents; Cochlea; Diuretics; Female; Furosemide; Gentamicins; Guinea Pigs; Hair Cells, Vestibular; Kanamycin; Otolithic Membrane; Vestibular Evoked Myogenic Potentials; Vestibular Function Tests	2012
Spatial overlap of combined electroacoustic stimulation determines the electrically evoked response in the guinea pig cochlea. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2012, Volume: 33, Issue:9 Topics: Acoustic Impedance Tests; Acoustic Stimulation; Action Potentials; Animals; Anti-Bacterial Agents; Cochlea; Data Interpretation, Statistical; Diuretics; Electric Stimulation; Evoked Potentials, Auditory; Female; Furosemide; Guinea Pigs; Hearing Loss, High-Frequency; Kanamycin; Noise	2012
Spiral ganglion cell morphology in guinea pigs after deafening and neurotrophic treatment. Hearing research, 2013, Volume: 298 Topics: Animals; Auditory Threshold; Brain-Derived Neurotrophic Factor; Cell Shape; Cell Size; Cell Survival; Deafness; Disease Models, Animal; Female; Furosemide; Ganglia, Spinal; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Nerve Degeneration; Neurons; Time Factors	2013
The peripheral processes of spiral ganglion cells after intracochlear application of brain-derived neurotrophic factor in deafened guinea pigs. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, Volume: 34, Issue:3 Topics: Animals; Brain-Derived Neurotrophic Factor; Deafness; Furosemide; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Myelin Sheath; Nerve Degeneration; Neurons; Spiral Ganglion	2013
Atoh1 induces auditory hair cell recovery in mice after ototoxic injury. The Laryngoscope, 2013, Volume: 123, Issue:4 Topics: Animals; Anti-Bacterial Agents; Basic Helix-Loop-Helix Transcription Factors; Cochlear Diseases; Diuretics; Furosemide; Genetic Therapy; Hair Cells, Auditory; Hearing Loss, Sensorineural; Kanamycin; Mice; Mice, Inbred C57BL; Regeneration	2013
Deafness induction in mice. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, Volume: 34, Issue:8 Topics: Animals; Disease Models, Animal; Diuretics; Furosemide; Hair Cells, Auditory; Hearing Loss, Sensorineural; Kanamycin; Mice; Spiral Ganglion	2013
A guinea pig model of selective severe high-frequency hearing loss. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2013, Volume: 34, Issue:8 Topics: Action Potentials; Animals; Cochlea; Disease Models, Animal; Furosemide; Guinea Pigs; Hair Cells, Auditory; Hearing; Hearing Loss, High-Frequency; Kanamycin	2013
[Math1 gene therapy for kanamycin and furosemide-induced deaf guinea pigs]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2013, Volume: 48, Issue:7 Topics: Adenoviridae; Animals; Basic Helix-Loop-Helix Transcription Factors; Cochlea; Deafness; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Furosemide; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Guinea Pigs; Hair Cells, Auditory; Hearing Loss; Kanamycin; Perilymph	2013
Kanamycin-furosemide ototoxicity in the mouse cochlea: a 3-dimensional analysis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2014, Volume: 150, Issue:4 Topics: Animals; Cochlea; Cochlear Diseases; Disease Models, Animal; Female; Furosemide; Hair Cells, Auditory; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Injections, Subcutaneous; Kanamycin; Mice; Mice, Inbred CBA; Microscopy, Confocal; Organ of Corti; Radiography; Random Allocation; Reference Values; Sensitivity and Specificity; Ultrasonography	2014
Development of an ototoxicity model in the adult CBA/CaJ mouse and determination of a golden window of corticosteroid intervention for otoprotection. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2014, Apr-24, Volume: 43 Topics: Animals; Cell Survival; Dexamethasone; Disease Models, Animal; Furosemide; Hair Cells, Auditory; Kanamycin; Male; Mice, Inbred CBA; Premedication; Time Factors; Translational Research, Biomedical	2014
Systemic lipopolysaccharide induces cochlear inflammation and exacerbates the synergistic ototoxicity of kanamycin and furosemide. Journal of the Association for Research in Otolaryngology : JARO, 2014, Volume: 15, Issue:4 Topics: Animals; Anti-Bacterial Agents; Cochlea; Cochlear Diseases; CX3C Chemokine Receptor 1; Disease Models, Animal; Drug Synergism; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory, Outer; Heterozygote; Inflammation; Kanamycin; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Receptors, Chemokine	2014
Local delivery of brain-derived neurotrophic factor on the perforated round window membrane in Guinea pigs: a possible clinical application. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2015, Volume: 36, Issue:4 Topics: Animals; Brain-Derived Neurotrophic Factor; Deafness; Disease Models, Animal; Drug Administration Routes; Evoked Potentials, Auditory, Brain Stem; Female; Furosemide; Guinea Pigs; Kanamycin; Round Window, Ear	2015
Recovery characteristics of the electrically stimulated auditory nerve in deafened guinea pigs: relation to neuronal status. Hearing research, 2015, Volume: 321 Topics: Animals; Auditory Perception; Cochlear Implantation; Cochlear Nerve; Disease Models, Animal; Electric Stimulation; Evoked Potentials, Auditory; Female; Furosemide; Guinea Pigs; Hearing; Hearing Loss, Sensorineural; Kanamycin; Nerve Degeneration; Perceptual Masking; Reaction Time; Recovery of Function; Refractory Period, Electrophysiological; Spiral Ganglion; Time Factors	2015
[The spiral ganglion degeneration and the expression of EFR3A in the cochlea of the deaf mice induced by co-administration of kanamycin and furosemide]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2014, Volume: 49, Issue:11 Topics: Animals; Cochlea; Furosemide; Hair Cells, Auditory; Kanamycin; Membrane Proteins; Mice; Mice, Inbred C57BL; Saccharomyces cerevisiae Proteins; Spiral Ganglion	2014
Establishment of a model of cochlear lesions in rats to study potential gene therapy for sensorineural hearing loss. International journal of pediatric otorhinolaryngology, 2015, Volume: 79, Issue:12 Topics: Adenoviridae; Animals; Axons; Cell Death; Disease Models, Animal; Furosemide; Gene Transfer Techniques; Genetic Therapy; Hair Cells, Auditory; Hearing Loss, Sensorineural; Kanamycin; Neurons; Organ of Corti; Rats, Sprague-Dawley; Regeneration; Spiral Ganglion; Transgenes	2015
Scar formation in mice deafened with kanamycin and furosemide. Microscopy research and technique, 2016, Volume: 79, Issue:8 Topics: Animals; Disease Models, Animal; Furosemide; Hair Cells, Auditory; Hearing Loss, Sensorineural; Kanamycin; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Organ of Corti	2016
Genetic disruption of fractalkine signaling leads to enhanced loss of cochlear afferents following ototoxic or acoustic injury. The Journal of comparative neurology, 2018, 04-01, Volume: 526, Issue:5 Topics: Acoustic Stimulation; Animals; Cell Survival; CX3C Chemokine Receptor 1; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Furosemide; Green Fluorescent Proteins; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Interleukin-1beta; Intermediate Filaments; Kanamycin; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Synthesis Inhibitors; Signal Transduction; Spiral Ganglion	2018
The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea. Hearing research, 2018, Volume: 358 Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Auditory Fatigue; Brain Stem; Cochlea; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Furosemide; Gene Expression Regulation; Hearing; Hearing Loss; Inflammation Mediators; Kanamycin; Male; Oxidative Stress; Rats, Wistar; Reaction Time; Resveratrol	2018
Upregulation of HSP60 expression in the postnatal rat cochlea and rats with drug-induced hearing loss. Cell stress & chaperones, 2018, Volume: 23, Issue:6 Topics: Animals; Auditory Threshold; Chaperonin 60; Cochlea; Evoked Potentials, Auditory, Brain Stem; Furosemide; Hair Cells, Auditory; Hearing Loss; Kanamycin; Labyrinth Supporting Cells; Mitochondrial Proteins; Rats; Rats, Sprague-Dawley; Spiral Ganglion; Transcriptional Activation; Up-Regulation	2018
Generation of new hair cells by DNA methyltransferase (Dnmt) inhibitor 5-azacytidine in a chemically-deafened mouse model. Scientific reports, 2019, 05-29, Volume: 9, Issue:1 Topics: Animals; Azacitidine; Cochlea; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; Ear, Inner; Enzyme Inhibitors; Furosemide; Hair Cells, Auditory, Inner; Hearing Loss; Humans; Kanamycin; Mice; Regeneration	2019
miR-182 prevented ototoxic deafness induced by co-administration of kanamycin and furosemide in rats. Neuroscience letters, 2020, 04-01, Volume: 723 Topics: Animals; Anti-Bacterial Agents; Deafness; Drug Combinations; Female; Furosemide; Kanamycin; MicroRNAs; Ototoxicity; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors	2020
Simultaneous rather than retrograde spiral ganglion cell degeneration following ototoxically induced hair cell loss in the guinea pig cochlea. Hearing research, 2020, Volume: 390 Topics: Animals; Auditory Threshold; Deafness; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Furosemide; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Nerve Degeneration; Ototoxicity; Spiral Ganglion	2020
Generation of Cochlear Hair Cells from Sox2 Positive Supporting Cells via DNA Demethylation. International journal of molecular sciences, 2020, Nov-17, Volume: 21, Issue:22 Topics: Animals; Azacitidine; DNA Methylation; Female; Furosemide; Hair Cells, Auditory; Hearing Loss; Kanamycin; Male; Mice; Mice, Transgenic; SOXB1 Transcription Factors	2020
Sensorineural hearing loss may lead to dementia-related pathological changes in hippocampal neurons. Neurobiology of disease, 2021, Volume: 156 Topics: Animals; Dementia; Female; Furosemide; Hearing Loss, Sensorineural; Hippocampus; Inflammation Mediators; Kanamycin; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurons; tau Proteins	2021
The ototoxic effect of locally applied kanamycin and furosemide in guinea pigs. Journal of neuroscience methods, 2022, Apr-15, Volume: 372 Topics: Animals; Cochlea; Deafness; Furosemide; Guinea Pigs; Hair Cells, Auditory; Kanamycin; Spiral Ganglion	2022
Refinement of systemic guinea pig deafening in hearing research: Sensorineural hearing loss induced by co-administration of kanamycin and furosemide via the leg veins. Laboratory animals, 2023, Volume: 57, Issue:6 Topics: Animals; Disease Models, Animal; Furosemide; Guinea Pigs; Hair Cells, Auditory; Hearing; Hearing Loss, Sensorineural; Humans; Kanamycin; Spiral Ganglion	2023
Agrobacterium tumefaciens-mediated genetic transformation of Salix matsudana Koidz. using mature seeds. Tree physiology, 2013, Volume: 33, Issue:6 Topics: Agrobacterium tumefaciens; Drug Resistance; Genes, Plant; Genetic Vectors; Germination; Kanamycin; Plant Development; Plant Roots; Plant Shoots; Plants, Genetically Modified; Salix; Seeds; Transformation, Genetic	2013