furosemide and ibuprofen

furosemide has been researched along with ibuprofen in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19907 (9.72)18.7374
1990's4 (5.56)18.2507
2000's24 (33.33)29.6817
2010's32 (44.44)24.3611
2020's5 (6.94)2.80

Authors

AuthorsStudies
Cha, SH; Endou, H; Kanai, Y; Kim, DK; Kim, JY; Kusuhara, H; Sekine, T; Sugiyama, Y; Yu, E1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T1
Chang, TK; Ensom, MH; Kiang, TK1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Akamatsu, M1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andrys, R; Capek, J; Handl, J; Hrabinova, M; Janockova, J; Kobrlova, T; Korabecny, J; Marco-Contelles, JL; Mezeiova, E; Micankova, P; Muckova, L; Nepovimova, E; Pejchal, J; Rousar, T; Simunkova, M; Soukup, O; Valko, M1
Deyrup-Olsen, I; Louie, H; Luchtel, DL; Martin, AW1
Copeland, S; Johnston, GD; Passmore, AP2
Ciancio, SG1
Anderson, S; Baird, B; Brater, DC; Campbell, WB1
Chremos, AN; Ferguson, RK; Johnson, CL; Riley, LJ; Rotmensch, HH; Swanson, BN; Vlasses, PH1
Poirier, TI1
Androsova, SO; Kutyrina, IM1
Laiwah, AC; Mactier, RA1
Haruta, A; Kodama, H; Otagiri, M; Suenaga, A; Takamura, N; Tsuruoka, M; Yamasaki, K1
Autere, A; Isonen, N; Marvola, M; Nykänen, P; Rautio, S1
Epstein, FH; Prasad, P1
Jürjenson, H; Linna, A; Marvola, M; Ojala, S; Säkkinen, M; Veski, P1
Lawrence, JR; Neu, TR; Swerhone, GD; Wassenaar, LI1
Danielsson, J; Dudley, A; Gelius, B; Gustavsson, L; Hollnack, E; Hoogstraate, J; Lohmann, C; Skoging-Nyberg, U; Wahlberg, J1
Biswas, D; Ghosh, M; Mukherjee, A1
Sourbron, S1
Frenzilli, G; Fusco, D; Peluso, C; Rocco, L; Stingo, V1
Jacobs, D; McGuinness, N; Paterson, CA; Rasmussen, S; Youngberg, SP1
Pacifici, GM1
Bueters, RR; Klaasen, A; Schreuder, MF; van den Heuvel, LP1
Jakimska, A; Kot-Wasik, A; Namieśnik, J; Reszczyńska, J; Śliwka-Kaszyńska, M1
Cheng, F; Fadli, Z; Huang, H; Lu, Y; Nagar, C; Pietsch, M; Shen, D; Tu, YC1
Almashanu, S; Bier Palmon, R; Eventov-Friedman, S; Flidel-Rimon, O; Golan, A; Kats, N; Keidar, R; Marom, R; Troitzky, M; Zung, A1
Feliczak-Guzik, A; Jadach, B; Lulek, J; Milanowski, B; Murias, M; Nowak, I; Piotrowska-Kempisty, H1
Blanco-Gozalo, V; García-Macías, MC; Hidalgo-Thomas, O; Kurtz, A; Layton, AT; López-Hernández, FJ; Martínez-Salgado, C; Morales, AI; Pericacho, M; Prieto-García, L; Sancho-Martínez, SM; Sanz, AB; Vicente-Vicente, L1
Bonsante, F; Gambacorta, S; Gouyon, B; Gouyon, JB; Iacobelli, S; Laforgia, N; Lorrain, S1
Al Ansari, E; Al Jufairi, M; Al Madhoob, A; Al Marzooq, R; Al Segai, O; Hashem Ahmed, H; Husain Shaban, G; Malalla, Z; Saeed Tabbara, K; Sridharan, K1
Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE1
Iori, V; Pietrini, F; Zacchini, M1

Reviews

4 review(s) available for furosemide and ibuprofen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants.
    Paediatric drugs, 2012, Aug-01, Volume: 14, Issue:4

    Topics: Acetazolamide; Bumetanide; Drug Therapy, Combination; Ductus Arteriosus, Patent; Extracorporeal Membrane Oxygenation; Furosemide; Humans; Hydrocephalus; Hypercalcemia; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Sodium Potassium Chloride Symporter Inhibitors

2012

Trials

7 trial(s) available for furosemide and ibuprofen

ArticleYear
The effects of ibuprofen and indomethacin on renal function in the presence and absence of frusemide in healthy volunteers on a restricted sodium diet.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:3

    Topics: Adult; Blood Pressure; Diet, Sodium-Restricted; Furosemide; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Inulin; Kidney; Kidney Function Tests; Male; Natriuresis; p-Aminohippuric Acid; Potassium; Renal Circulation; Renin; Sodium

1990
A comparison of the effects of ibuprofen and indomethacin upon renal haemodynamics and electrolyte excretion in the presence and absence of frusemide.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:4

    Topics: Adult; Creatinine; Electrolytes; Furosemide; Humans; Ibuprofen; Indomethacin; Male; p-Aminohippuric Acid; Potassium; Renal Circulation; Renin; Time Factors

1989
Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men.
    Kidney international, 1985, Volume: 27, Issue:1

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Kidney; Male; Naproxen; Prostaglandins; Random Allocation; Renin; Sulindac; Thromboxanes

1985
Sulindac and ibuprofen inhibit furosemide-stimulated renin release but not natriuresis in men on a normal sodium diet.
    Nephron, 1985, Volume: 41, Issue:3

    Topics: Adult; Chlorides; Diet; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Male; Natriuresis; Potassium; Renin; Sodium; Sulindac; Time Factors

1985
Enteric polymers as binders and coating materials in multiple-unit site-specific drug delivery systems.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 7, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diuretics; Drug Delivery Systems; Excipients; Female; Furosemide; Humans; Ibuprofen; Male; Polymers; Solubility

1999
In vivo evaluation of matrix granules containing microcrystalline chitosan as a gel-forming excipient.
    International journal of pharmaceutics, 2003, Jan-02, Volume: 250, Issue:1

    Topics: Adult; Biological Availability; Chitin; Chitosan; Cross-Over Studies; Excipients; Furosemide; Gastric Mucosa; Gels; Humans; Ibuprofen

2003
Randomized, open-label, 5-way crossover study to evaluate the pharmacokinetic/pharmacodynamic interaction between furosemide and the non-steroidal anti-inflammatory drugs diclofenac and ibuprofen in healthy volunteers.
    International journal of clinical pharmacology and therapeutics, 2011, Volume: 49, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cross-Over Studies; Diclofenac; Diuretics; Drug Interactions; Female; Furosemide; Humans; Ibuprofen; Male; Middle Aged; Transdermal Patch; Young Adult

2011

Other Studies

61 other study(ies) available for furosemide and ibuprofen

ArticleYear
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.
    The Journal of biological chemistry, 2000, Feb-11, Volume: 275, Issue:6

    Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Dehydroepiandrosterone Sulfate; Estrone; Humans; Kidney; Kinetics; Membrane Proteins; Molecular Sequence Data; Ochratoxins; Oocytes; Placenta; RNA, Messenger; Sequence Alignment; Sulfates; Xenopus

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis

2001
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2021, Feb-05, Volume: 211

    Topics: Alzheimer Disease; Drug Design; Humans; Naphthoquinones; Structure-Activity Relationship

2021
Triggering by ATP of product release by mucous granules of the land slug Ariolimax columbianus.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1

    Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cytoplasmic Granules; Dinoprostone; Electric Stimulation; Ethylmaleimide; Furosemide; Ibuprofen; Indomethacin; Kinetics; Microscopy, Electron; Mollusca; Mucous Membrane; Nigericin; Pertussis Toxin; Tetradecanoylphorbol Acetate; Verapamil; Virulence Factors, Bordetella

1992
More commonly prescribed medications.
    Dental management, 1988, Volume: 28, Issue:6

    Topics: Alprazolam; Atenolol; Dental Care; Drug Therapy; Furosemide; Humans; Ibuprofen; Propranolol

1988
Reversible renal failure associated with ibuprofen: case report and review of the literature.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:1

    Topics: Acute Kidney Injury; Aged; Blood Urea Nitrogen; Carbon Dioxide; Creatinine; Female; Furosemide; Humans; Ibuprofen; Potassium

1984
[Reversible acute renal failure caused by brufen].
    Klinicheskaia meditsina, 1984, Volume: 62, Issue:5

    Topics: Acute Kidney Injury; Aged; Female; Fenoprofen; Furosemide; Humans; Ibuprofen; Kidney Failure, Chronic; Phenylpropionates

1984
Antagonistic effect of non-steroidal anti-inflammatory drugs on frusemide-induced diuresis in cardiac failure.
    British medical journal (Clinical research ed.), 1981, Sep-12, Volume: 283, Issue:6293

    Topics: Aged; Diuresis; Female; Furosemide; Heart Failure; Humans; Ibuprofen; Male; Naproxen

1981
Mode of interaction of loop diuretics with human serum albumin and characterization of binding site.
    Pharmaceutical research, 1996, Volume: 13, Issue:7

    Topics: Binding Sites; Diuretics; Fluorescent Dyes; Furosemide; Humans; Ibuprofen; Lysine; Protein Binding; Serum Albumin; Sulfonamides; Warfarin

1996
Effects of furosemide on medullary oxygenation in younger and older subjects.
    Kidney international, 2000, Volume: 57, Issue:5

    Topics: Adult; Aging; Female; Furosemide; Humans; Ibuprofen; Kidney Medulla; Magnetic Resonance Imaging; Male; Oxygen

2000
Effects of selected pharmaceuticals on riverine biofilm communities.
    Canadian journal of microbiology, 2005, Volume: 51, Issue:8

    Topics: Bacteria; Biofilms; Bioreactors; Caffeine; Carbamazepine; Carbon Isotopes; Colony Count, Microbial; Drug Prescriptions; Ecosystem; Furosemide; Ibuprofen; In Situ Hybridization, Fluorescence; Microscopy, Confocal; Pharmaceutical Preparations; Rivers

2005
Scintillation proximity assay for measuring uptake by the human drug transporters hOCT1, hOAT3, and hOATP1B1.
    Analytical biochemistry, 2007, Jul-15, Volume: 366, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carbon Isotopes; Cell Line; Furosemide; Glucuronides; Humans; Ibuprofen; Kinetics; Linear Models; Liver-Specific Organic Anion Transporter 1; Octamer Transcription Factor-1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Plasmids; Scintillation Counting; Sodium Potassium Chloride Symporter Inhibitors; Tetraethylammonium; Transfection; Tritium

2007
High-altitude medicines: a short-term genotoxicity study.
    Toxicology and industrial health, 2010, Volume: 26, Issue:7

    Topics: Acetazolamide; Adult; Altitude Sickness; Analysis of Variance; Cell Survival; Cells, Cultured; Comet Assay; Dexamethasone; DNA; DNA Damage; Furosemide; Humans; Ibuprofen; Lymphocytes; Male; Mutagenicity Tests; Nifedipine; Theophylline

2010
Compartmental modelling for magnetic resonance renography.
    Zeitschrift fur medizinische Physik, 2010, Volume: 20, Issue:2

    Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Computer Simulation; Cyclooxygenase Inhibitors; Diabetic Nephropathies; Diuresis; Diuretics; Drug Therapy, Combination; Furosemide; Glomerular Filtration Rate; Humans; Ibuprofen; Kidney Diseases; Kidney Transplantation; Magnetic Resonance Imaging; Oxygen; Radioisotope Renography; Rats; Renal Artery Obstruction; Signal Transduction; Ureteral Obstruction

2010
Evaluation of zebrafish DNA integrity after exposure to pharmacological agents present in aquatic environments.
    Ecotoxicology and environmental safety, 2010, Volume: 73, Issue:7

    Topics: Animals; Bezafibrate; Comet Assay; DNA Damage; Drug Residues; Environmental Pollutants; Furosemide; Ibuprofen; Lipid Regulating Agents; Microscopy, Fluorescence; Random Amplified Polymorphic DNA Technique; Zebrafish

2010
Effect of NSAIDs and diuretics on nephrogenesis in an ex vivo embryogenic kidney model.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2013, Volume: 98, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Morphogenetic Protein 7; Diuretics; Female; Fibroblast Growth Factor 8; Furosemide; Gene Expression; Gene Expression Profiling; Glial Cell Line-Derived Neurotrophic Factor; Hydrochlorothiazide; Ibuprofen; Indomethacin; Kidney; Mice; Mice, Inbred ICR; Organ Culture Techniques; Pregnancy; SOX9 Transcription Factor; WT1 Proteins

2013
Elucidation of transformation pathway of ketoprofen, ibuprofen, and furosemide in surface water and their occurrence in the aqueous environment using UHPLC-QTOF-MS.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:15

    Topics: Chromatography, Liquid; Ecotoxicology; Environment; Environmental Monitoring; Furosemide; Ibuprofen; Ketoprofen; Kinetics; Mass Spectrometry; Photochemistry; Photolysis; Rivers; Wastewater; Water Pollutants, Chemical; Water Purification; Xenon

2014
A novel algorithm for analyzing drug-drug interactions from MEDLINE literature.
    Scientific reports, 2015, Nov-27, Volume: 5

    Topics: Algorithms; Contraindications; Drug Interactions; Enzymes; Furosemide; Humans; Hydrolysis; Ibuprofen; MEDLINE; Sertraline; Warfarin

2015
Risk Factors for the Development of Delayed TSH Elevation in Neonatal Intensive Care Unit Newborns.
    The Journal of clinical endocrinology and metabolism, 2017, 08-01, Volume: 102, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Cefotaxime; Cesarean Section; Diuretics; Dopamine; Ductus Arteriosus, Patent; Erythrocyte Transfusion; Female; Fluconazole; Furosemide; Humans; Hypoglycemic Agents; Hypothyroidism; Ibuprofen; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Insulin; Intensive Care Units, Neonatal; Male; Multivariate Analysis; Neonatal Screening; Pneumothorax; Respiration, Artificial; Retrospective Studies; Risk Factors; Sympathomimetics; Thyrotropin; Time Factors; Vancomycin

2017
Modifying release of poorly soluble active pharmaceutical ingredients with the amine functionalized SBA-16 type mesoporous materials.
    Journal of biomaterials applications, 2019, Volume: 33, Issue:9

    Topics: Amination; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Diuretics; Drug Carriers; Drug Liberation; Furosemide; Humans; Ibuprofen; Permeability; Porosity; Silicon Dioxide; Solubility

2019
Pathophysiological mechanisms underlying a rat model of triple whammy acute kidney injury.
    Laboratory investigation; a journal of technical methods and pathology, 2020, Volume: 100, Issue:11

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Disease Models, Animal; Diuretics; Drug Therapy, Combination; Furosemide; Ibuprofen; Indoles; Male; Rats, Wistar; Renal Circulation

2020
Drug exposure for PDA closure in France: a prospective, cohort-based, analysis.
    European journal of clinical pharmacology, 2020, Volume: 76, Issue:12

    Topics: Acetaminophen; Administration, Oral; Drug Resistance; Drug Utilization; Ductus Arteriosus, Patent; Female; France; Furosemide; Hospitalization; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Male; Practice Patterns, Physicians'; Prospective Studies; Treatment Outcome

2020
Biomarkers in neonates receiving potential nephrotoxic drugs.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:22

    Topics: Acetaminophen; Adult; Amikacin; Biomarkers; Cystatins; Female; Furosemide; Gentamicins; Hepatitis A Virus Cellular Receptor 1; Humans; Ibuprofen; Infant, Newborn; Kidney Diseases; Lipocalin-2; Male; Middle Aged; Vancomycin

2021
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
    Drug safety, 2022, Volume: 45, Issue:11

    Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid

2022
Growth, physiological response and phytoremoval capability of two willow clones exposed to ibuprofen under hydroponic culture.
    Journal of hazardous materials, 2013, Nov-15, Volume: 262

    Topics: Biodegradation, Environmental; Chlorophyll; Hydroponics; Ibuprofen; Malondialdehyde; Photosynthesis; Plant Leaves; Plant Roots; Plant Stems; Salix; Water Pollutants, Chemical

2013