furosemide has been researched along with ibuprofen in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (9.72) | 18.7374 |
1990's | 4 (5.56) | 18.2507 |
2000's | 24 (33.33) | 29.6817 |
2010's | 32 (44.44) | 24.3611 |
2020's | 5 (6.94) | 2.80 |
Authors | Studies |
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Cha, SH; Endou, H; Kanai, Y; Kim, DK; Kim, JY; Kusuhara, H; Sekine, T; Sugiyama, Y; Yu, E | 1 |
Strassburg, CP; Tukey, RH | 1 |
Topliss, JG; Yoshida, F | 1 |
Faller, B; Wohnsland, F | 1 |
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
Chang, TK; Ensom, MH; Kiang, TK | 1 |
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
Caron, G; Ermondi, G | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Avdeef, A; Tam, KY | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
Akamatsu, M | 1 |
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Andrys, R; Capek, J; Handl, J; Hrabinova, M; Janockova, J; Kobrlova, T; Korabecny, J; Marco-Contelles, JL; Mezeiova, E; Micankova, P; Muckova, L; Nepovimova, E; Pejchal, J; Rousar, T; Simunkova, M; Soukup, O; Valko, M | 1 |
Deyrup-Olsen, I; Louie, H; Luchtel, DL; Martin, AW | 1 |
Copeland, S; Johnston, GD; Passmore, AP | 2 |
Ciancio, SG | 1 |
Anderson, S; Baird, B; Brater, DC; Campbell, WB | 1 |
Chremos, AN; Ferguson, RK; Johnson, CL; Riley, LJ; Rotmensch, HH; Swanson, BN; Vlasses, PH | 1 |
Poirier, TI | 1 |
Androsova, SO; Kutyrina, IM | 1 |
Laiwah, AC; Mactier, RA | 1 |
Haruta, A; Kodama, H; Otagiri, M; Suenaga, A; Takamura, N; Tsuruoka, M; Yamasaki, K | 1 |
Autere, A; Isonen, N; Marvola, M; Nykänen, P; Rautio, S | 1 |
Epstein, FH; Prasad, P | 1 |
Jürjenson, H; Linna, A; Marvola, M; Ojala, S; Säkkinen, M; Veski, P | 1 |
Lawrence, JR; Neu, TR; Swerhone, GD; Wassenaar, LI | 1 |
Danielsson, J; Dudley, A; Gelius, B; Gustavsson, L; Hollnack, E; Hoogstraate, J; Lohmann, C; Skoging-Nyberg, U; Wahlberg, J | 1 |
Biswas, D; Ghosh, M; Mukherjee, A | 1 |
Sourbron, S | 1 |
Frenzilli, G; Fusco, D; Peluso, C; Rocco, L; Stingo, V | 1 |
Jacobs, D; McGuinness, N; Paterson, CA; Rasmussen, S; Youngberg, SP | 1 |
Pacifici, GM | 1 |
Bueters, RR; Klaasen, A; Schreuder, MF; van den Heuvel, LP | 1 |
Jakimska, A; Kot-Wasik, A; Namieśnik, J; Reszczyńska, J; Śliwka-Kaszyńska, M | 1 |
Cheng, F; Fadli, Z; Huang, H; Lu, Y; Nagar, C; Pietsch, M; Shen, D; Tu, YC | 1 |
Almashanu, S; Bier Palmon, R; Eventov-Friedman, S; Flidel-Rimon, O; Golan, A; Kats, N; Keidar, R; Marom, R; Troitzky, M; Zung, A | 1 |
Feliczak-Guzik, A; Jadach, B; Lulek, J; Milanowski, B; Murias, M; Nowak, I; Piotrowska-Kempisty, H | 1 |
Blanco-Gozalo, V; García-Macías, MC; Hidalgo-Thomas, O; Kurtz, A; Layton, AT; López-Hernández, FJ; Martínez-Salgado, C; Morales, AI; Pericacho, M; Prieto-García, L; Sancho-Martínez, SM; Sanz, AB; Vicente-Vicente, L | 1 |
Bonsante, F; Gambacorta, S; Gouyon, B; Gouyon, JB; Iacobelli, S; Laforgia, N; Lorrain, S | 1 |
Al Ansari, E; Al Jufairi, M; Al Madhoob, A; Al Marzooq, R; Al Segai, O; Hashem Ahmed, H; Husain Shaban, G; Malalla, Z; Saeed Tabbara, K; Sridharan, K | 1 |
Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE | 1 |
Iori, V; Pietrini, F; Zacchini, M | 1 |
4 review(s) available for furosemide and ibuprofen
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants.
Topics: Acetazolamide; Bumetanide; Drug Therapy, Combination; Ductus Arteriosus, Patent; Extracorporeal Membrane Oxygenation; Furosemide; Humans; Hydrocephalus; Hypercalcemia; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Sodium Potassium Chloride Symporter Inhibitors | 2012 |
7 trial(s) available for furosemide and ibuprofen
Article | Year |
---|---|
The effects of ibuprofen and indomethacin on renal function in the presence and absence of frusemide in healthy volunteers on a restricted sodium diet.
Topics: Adult; Blood Pressure; Diet, Sodium-Restricted; Furosemide; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Inulin; Kidney; Kidney Function Tests; Male; Natriuresis; p-Aminohippuric Acid; Potassium; Renal Circulation; Renin; Sodium | 1990 |
A comparison of the effects of ibuprofen and indomethacin upon renal haemodynamics and electrolyte excretion in the presence and absence of frusemide.
Topics: Adult; Creatinine; Electrolytes; Furosemide; Humans; Ibuprofen; Indomethacin; Male; p-Aminohippuric Acid; Potassium; Renal Circulation; Renin; Time Factors | 1989 |
Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Kidney; Male; Naproxen; Prostaglandins; Random Allocation; Renin; Sulindac; Thromboxanes | 1985 |
Sulindac and ibuprofen inhibit furosemide-stimulated renin release but not natriuresis in men on a normal sodium diet.
Topics: Adult; Chlorides; Diet; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Male; Natriuresis; Potassium; Renin; Sodium; Sulindac; Time Factors | 1985 |
Enteric polymers as binders and coating materials in multiple-unit site-specific drug delivery systems.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diuretics; Drug Delivery Systems; Excipients; Female; Furosemide; Humans; Ibuprofen; Male; Polymers; Solubility | 1999 |
In vivo evaluation of matrix granules containing microcrystalline chitosan as a gel-forming excipient.
Topics: Adult; Biological Availability; Chitin; Chitosan; Cross-Over Studies; Excipients; Furosemide; Gastric Mucosa; Gels; Humans; Ibuprofen | 2003 |
Randomized, open-label, 5-way crossover study to evaluate the pharmacokinetic/pharmacodynamic interaction between furosemide and the non-steroidal anti-inflammatory drugs diclofenac and ibuprofen in healthy volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cross-Over Studies; Diclofenac; Diuretics; Drug Interactions; Female; Furosemide; Humans; Ibuprofen; Male; Middle Aged; Transdermal Patch; Young Adult | 2011 |
61 other study(ies) available for furosemide and ibuprofen
Article | Year |
---|---|
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Dehydroepiandrosterone Sulfate; Estrone; Humans; Kidney; Kinetics; Membrane Proteins; Molecular Sequence Data; Ochratoxins; Oocytes; Placenta; RNA, Messenger; Sequence Alignment; Sulfates; Xenopus | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Drug Design; Humans; Naphthoquinones; Structure-Activity Relationship | 2021 |
Triggering by ATP of product release by mucous granules of the land slug Ariolimax columbianus.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cytoplasmic Granules; Dinoprostone; Electric Stimulation; Ethylmaleimide; Furosemide; Ibuprofen; Indomethacin; Kinetics; Microscopy, Electron; Mollusca; Mucous Membrane; Nigericin; Pertussis Toxin; Tetradecanoylphorbol Acetate; Verapamil; Virulence Factors, Bordetella | 1992 |
More commonly prescribed medications.
Topics: Alprazolam; Atenolol; Dental Care; Drug Therapy; Furosemide; Humans; Ibuprofen; Propranolol | 1988 |
Reversible renal failure associated with ibuprofen: case report and review of the literature.
Topics: Acute Kidney Injury; Aged; Blood Urea Nitrogen; Carbon Dioxide; Creatinine; Female; Furosemide; Humans; Ibuprofen; Potassium | 1984 |
[Reversible acute renal failure caused by brufen].
Topics: Acute Kidney Injury; Aged; Female; Fenoprofen; Furosemide; Humans; Ibuprofen; Kidney Failure, Chronic; Phenylpropionates | 1984 |
Antagonistic effect of non-steroidal anti-inflammatory drugs on frusemide-induced diuresis in cardiac failure.
Topics: Aged; Diuresis; Female; Furosemide; Heart Failure; Humans; Ibuprofen; Male; Naproxen | 1981 |
Mode of interaction of loop diuretics with human serum albumin and characterization of binding site.
Topics: Binding Sites; Diuretics; Fluorescent Dyes; Furosemide; Humans; Ibuprofen; Lysine; Protein Binding; Serum Albumin; Sulfonamides; Warfarin | 1996 |
Effects of furosemide on medullary oxygenation in younger and older subjects.
Topics: Adult; Aging; Female; Furosemide; Humans; Ibuprofen; Kidney Medulla; Magnetic Resonance Imaging; Male; Oxygen | 2000 |
Effects of selected pharmaceuticals on riverine biofilm communities.
Topics: Bacteria; Biofilms; Bioreactors; Caffeine; Carbamazepine; Carbon Isotopes; Colony Count, Microbial; Drug Prescriptions; Ecosystem; Furosemide; Ibuprofen; In Situ Hybridization, Fluorescence; Microscopy, Confocal; Pharmaceutical Preparations; Rivers | 2005 |
Scintillation proximity assay for measuring uptake by the human drug transporters hOCT1, hOAT3, and hOATP1B1.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carbon Isotopes; Cell Line; Furosemide; Glucuronides; Humans; Ibuprofen; Kinetics; Linear Models; Liver-Specific Organic Anion Transporter 1; Octamer Transcription Factor-1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Plasmids; Scintillation Counting; Sodium Potassium Chloride Symporter Inhibitors; Tetraethylammonium; Transfection; Tritium | 2007 |
High-altitude medicines: a short-term genotoxicity study.
Topics: Acetazolamide; Adult; Altitude Sickness; Analysis of Variance; Cell Survival; Cells, Cultured; Comet Assay; Dexamethasone; DNA; DNA Damage; Furosemide; Humans; Ibuprofen; Lymphocytes; Male; Mutagenicity Tests; Nifedipine; Theophylline | 2010 |
Compartmental modelling for magnetic resonance renography.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Computer Simulation; Cyclooxygenase Inhibitors; Diabetic Nephropathies; Diuresis; Diuretics; Drug Therapy, Combination; Furosemide; Glomerular Filtration Rate; Humans; Ibuprofen; Kidney Diseases; Kidney Transplantation; Magnetic Resonance Imaging; Oxygen; Radioisotope Renography; Rats; Renal Artery Obstruction; Signal Transduction; Ureteral Obstruction | 2010 |
Evaluation of zebrafish DNA integrity after exposure to pharmacological agents present in aquatic environments.
Topics: Animals; Bezafibrate; Comet Assay; DNA Damage; Drug Residues; Environmental Pollutants; Furosemide; Ibuprofen; Lipid Regulating Agents; Microscopy, Fluorescence; Random Amplified Polymorphic DNA Technique; Zebrafish | 2010 |
Effect of NSAIDs and diuretics on nephrogenesis in an ex vivo embryogenic kidney model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Morphogenetic Protein 7; Diuretics; Female; Fibroblast Growth Factor 8; Furosemide; Gene Expression; Gene Expression Profiling; Glial Cell Line-Derived Neurotrophic Factor; Hydrochlorothiazide; Ibuprofen; Indomethacin; Kidney; Mice; Mice, Inbred ICR; Organ Culture Techniques; Pregnancy; SOX9 Transcription Factor; WT1 Proteins | 2013 |
Elucidation of transformation pathway of ketoprofen, ibuprofen, and furosemide in surface water and their occurrence in the aqueous environment using UHPLC-QTOF-MS.
Topics: Chromatography, Liquid; Ecotoxicology; Environment; Environmental Monitoring; Furosemide; Ibuprofen; Ketoprofen; Kinetics; Mass Spectrometry; Photochemistry; Photolysis; Rivers; Wastewater; Water Pollutants, Chemical; Water Purification; Xenon | 2014 |
A novel algorithm for analyzing drug-drug interactions from MEDLINE literature.
Topics: Algorithms; Contraindications; Drug Interactions; Enzymes; Furosemide; Humans; Hydrolysis; Ibuprofen; MEDLINE; Sertraline; Warfarin | 2015 |
Risk Factors for the Development of Delayed TSH Elevation in Neonatal Intensive Care Unit Newborns.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Cefotaxime; Cesarean Section; Diuretics; Dopamine; Ductus Arteriosus, Patent; Erythrocyte Transfusion; Female; Fluconazole; Furosemide; Humans; Hypoglycemic Agents; Hypothyroidism; Ibuprofen; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Insulin; Intensive Care Units, Neonatal; Male; Multivariate Analysis; Neonatal Screening; Pneumothorax; Respiration, Artificial; Retrospective Studies; Risk Factors; Sympathomimetics; Thyrotropin; Time Factors; Vancomycin | 2017 |
Modifying release of poorly soluble active pharmaceutical ingredients with the amine functionalized SBA-16 type mesoporous materials.
Topics: Amination; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Diuretics; Drug Carriers; Drug Liberation; Furosemide; Humans; Ibuprofen; Permeability; Porosity; Silicon Dioxide; Solubility | 2019 |
Pathophysiological mechanisms underlying a rat model of triple whammy acute kidney injury.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Disease Models, Animal; Diuretics; Drug Therapy, Combination; Furosemide; Ibuprofen; Indoles; Male; Rats, Wistar; Renal Circulation | 2020 |
Drug exposure for PDA closure in France: a prospective, cohort-based, analysis.
Topics: Acetaminophen; Administration, Oral; Drug Resistance; Drug Utilization; Ductus Arteriosus, Patent; Female; France; Furosemide; Hospitalization; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Male; Practice Patterns, Physicians'; Prospective Studies; Treatment Outcome | 2020 |
Biomarkers in neonates receiving potential nephrotoxic drugs.
Topics: Acetaminophen; Adult; Amikacin; Biomarkers; Cystatins; Female; Furosemide; Gentamicins; Hepatitis A Virus Cellular Receptor 1; Humans; Ibuprofen; Infant, Newborn; Kidney Diseases; Lipocalin-2; Male; Middle Aged; Vancomycin | 2021 |
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid | 2022 |
Growth, physiological response and phytoremoval capability of two willow clones exposed to ibuprofen under hydroponic culture.
Topics: Biodegradation, Environmental; Chlorophyll; Hydroponics; Ibuprofen; Malondialdehyde; Photosynthesis; Plant Leaves; Plant Roots; Plant Stems; Salix; Water Pollutants, Chemical | 2013 |