Compounds > furosemide

furosemide and guanfacine

furosemide has been researched along with guanfacine in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (9.09)	18.7374
1990's	1 (9.09)	18.2507
2000's	3 (27.27)	29.6817
2010's	6 (54.55)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Román, O; Salazar, R; Valenzuela, MA	1
Intengan, HD; Smyth, DD	1
Aragno, M; Mastrocola, R; Parola, M; Sansoè, G	1
Aragno, M; Mastrocola, R; Mengozzi, G; Parola, M; Sansoè, G	1

Reviews

1 review(s) available for furosemide and guanfacine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for furosemide and guanfacine

Article	Year
[Guanfacine in primary arterial hypertension: a long-term open clinical study]. Revista medica de Chile, 1982, Volume: 110, Issue:12 Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Furosemide; Guanfacine; Guanidines; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Phenylacetates; Propranolol	1982

Other Studies

9 other study(ies) available for furosemide and guanfacine

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Renal alpha 2a/d-adrenoceptor subtype function: Wistar as compared to spontaneously hypertensive rats. British journal of pharmacology, 1997, Volume: 121, Issue:5 Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Diuresis; Diuretics; Dose-Response Relationship, Drug; Furosemide; Guanfacine; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, alpha-2; Species Specificity	1997
Pathogenesis of solute-free water retention in experimental ascitic cirrhosis: is vasopressin the only culprit? Clinical science (London, England : 1979), 2016, Volume: 130, Issue:2 Topics: Animals; Ascites; Canrenoic Acid; Diuretics; Furosemide; Guanfacine; Hyponatremia; Liver Cirrhosis, Experimental; Male; Natriuresis; Norepinephrine; Rats; Rats, Wistar; Vasopressins	2016
Alpha-2A Adrenoceptor Agonist Guanfacine Restores Diuretic Efficiency in Experimental Cirrhotic Ascites: Comparison with Clonidine. PloS one, 2016, Volume: 11, Issue:7 Topics: Adrenergic Agonists; Animals; Ascites; Canrenoic Acid; Clonidine; Diuretics; Drug Synergism; Fibrosis; Furosemide; Guanfacine; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2	2016