furegrelate has been researched along with thromboxane b2 in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (64.29) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolling, SF; Deeb, GM; Grum, CM; Ljungman, AG; Morganroth, ML | 1 |
| Ji, TH; Murdoch, WJ; Slaughter, RG; Van Kirk, EA; Wilken, C | 1 |
| Glovsky, MM; Horvath, SJ; Morganroth, ML; Schoeneich, SO; Till, GO; Ward, PA | 1 |
| Kaushal, RD; Wilson, TW | 1 |
| Clark, WF; Kreeft, J; McDonald, JW; Parbtani, A; Reid, BD; Taylor, N | 1 |
| Franzini, D; Lawson, D; Mehta, J; Nichols, WW; Wargovich, TJ | 1 |
| Regal, JF | 2 |
| Friehling, TD; Kowey, PR; O'Connor, KM | 1 |
| Gréen, K; Vesterqvist, O | 1 |
| Cronenwett, JL; Huntsman, WT; McDaniel, MD; Miett, TO | 1 |
| Datar, S; McCauley, FA; Wilson, TW | 2 |
| Anderson, CB; Freeman, MB; Mangino, MJ; Neuberger, S; Sicard, GA; Valentin, LI | 1 |
| Cumming, AD; Lindsay, RM; Linton, AL; McDonald, JW | 1 |
| Keith, JC; Schaub, RG; Thatcher, CD | 1 |
| Anner, H; Hechtman, HB; Kaufman, RP; Kobzik, L; Shepro, D; Valeri, CR | 1 |
| Boorstein, JM; Cronenwett, JL; Endean, ED; Hees, PL | 1 |
| Jackson, EK | 1 |
| Aiken, JW; Gorman, RR; Johnson, RA; Spilman, CH | 1 |
| Hock, CE; Lefer, AM | 1 |
| Fitzpatrick, FA; Liggett, WF; Wynalda, MA | 1 |
| Krupa, SM; Lane, PH; Reddington, JC; Salinas-Madrigal, L; Schmitz, PG | 1 |
| Murakami, Y; Nishihara, M; Okada, S; Osumi, Y; Yokotani, K | 1 |
| Berens, ME; Djawaheri, J; Giese, A; Hagel, C; Kim, EL; Westphal, M; Zapf, S | 1 |
| Jungermann, K; Nath, A; Pestel, S; Schieferdecker, HL | 1 |
| Gendron, ME; Thorin, E | 1 |
| Ansari, HR; Mustafa, SJ; Nadeem, A; Tilley, SL | 1 |
28 other study(ies) available for furegrelate and thromboxane b2
| Article | Year |
|---|---|
Inhibition of cyclooxygenase metabolite production attenuates ischemia-reperfusion lung injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Pressure; Cyclooxygenase Inhibitors; Dinoprost; Flurbiprofen; Hydrogen Peroxide; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Rats; Rats, Inbred Strains; Reperfusion Injury; Thromboxane B2; Thromboxane-A Synthase | 1991 |
Increased production of ovarian thromboxane in gonadotropin-treated immature rats: relationship to the ovulatory process.
Topics: Animals; Benzofurans; Biphenyl Compounds; Chorionic Gonadotropin; Female; Gonadotropins; Gonadotropins, Equine; Indomethacin; Ovary; Ovulation; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes | 1990 |
C3a57-77, a C-terminal peptide, causes thromboxane-dependent pulmonary vascular constriction in isolated perfused rat lungs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Pressure; Complement C3a; Cyclooxygenase Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Male; Peptide Fragments; Perfusion; Pyridines; Rats; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction | 1990 |
Effect of furegrelate on renal plasma flow after angiotensin II infusion.
Topics: Angiotensin II; Animals; Benzofurans; Blood Pressure; Indomethacin; Infusions, Intravenous; Male; p-Aminohippuric Acid; Rats; Rats, Inbred Strains; Renal Circulation; Thromboxane B2; Thromboxane-A Synthase | 1990 |
The effects of a thromboxane synthase inhibitor, a prostacyclin analog and PGE1 on the nephritis of the NZB/W F1 mouse.
Topics: 6-Ketoprostaglandin F1 alpha; Age Factors; Alprostadil; Animals; Benzofurans; Blood Pressure; Disease Models, Animal; Epoprostenol; Female; Iloprost; Lupus Nephritis; Mice; Mice, Inbred NZB; Mice, Inbred Strains; Nephritis; Proteinuria; Thromboxane B2; Vasodilator Agents | 1987 |
Reduced myocardial neutrophil accumulation and infarct size following thromboxane synthetase inhibitor or receptor antagonist.
Topics: Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Chemotaxis, Leukocyte; Creatine Kinase; Epoprostenol; Fatty Acids, Unsaturated; Hydrazines; Male; Myocardial Infarction; Myocardium; Neutrophils; Peroxidase; Platelet Aggregation; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1989 |
Mediators of C5a-induced bronchoconstriction.
Topics: Animals; Benzofurans; Bronchi; Complement C5; Complement C5a; Guinea Pigs; Leukotriene B4; Male; Phenylbutyrates; Thromboxane B2 | 1987 |
Role of arachidonate metabolites in C5a-induced bronchoconstriction.
Topics: Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Bronchi; Complement C5; Complement C5a; Dinoprost; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; Injections, Intravenous; Leukotriene B4; Lung; Prostaglandin D2; Prostaglandins D; Prostaglandins F; Thromboxane B2; Thromboxane-A Synthase | 1988 |
The effect of thromboxane inhibition on vulnerability to ventricular fibrillation in the acute and chronic feline infarction models.
Topics: Acute Disease; Animals; Benzofurans; Cardiac Pacing, Artificial; Cats; Chronic Disease; Female; Male; Myocardial Infarction; Myocardial Reperfusion; Thromboxane B2; Thromboxane-A Synthase; Ventricular Fibrillation | 1989 |
In vivo synthesis of thromboxane and prostacyclin in man in health and disease. Data from GC-MS measurements of major urinary metabolites.
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Blood Vessel Prosthesis; Epoprostenol; Gas Chromatography-Mass Spectrometry; Humans; Myocardial Infarction; Thromboxane A2; Thromboxane B2 | 1986 |
Effect of a selective thromboxane synthase inhibitor on arterial graft patency and platelet deposition in dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Arteries; Aspirin; Benzofurans; Blood Platelets; Blood Vessel Prosthesis; Carotid Arteries; Dipyridamole; Dogs; Female; Indium; Polyethylene Terephthalates; Polytetrafluoroethylene; Radioisotopes; Random Allocation; Thromboxane B2; Thromboxane-A Synthase | 1987 |
Effect of cyclooxygenase and thromboxane synthetase inhibition on furosemide-stimulated plasma renin activity.
Topics: Animals; Benzofurans; Cyclooxygenase Inhibitors; Furosemide; Indomethacin; Male; Rats; Rats, Inbred Strains; Renin; Thromboxane B2; Thromboxane-A Synthase | 1987 |
The association of in vitro arachidonic acid responsiveness and plasma thromboxane levels with early platelet deposition on the luminal surface of small-diameter grafts.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Benzofurans; Blood Vessel Prosthesis; Dogs; Graft Occlusion, Vascular; Platelet Aggregation; Polytetrafluoroethylene; Thromboxane B2; Thromboxane-A Synthase | 1988 |
Testing the "redirection hypothesis" of prostaglandin metabolism in the kidney.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Drug Interactions; Furosemide; Kidney; Male; Prostaglandins; Rats; Rats, Inbred Strains; Renin; Thromboxane B2; Thromboxane-A Synthase | 1987 |
Acute effect of a thromboxane synthetase inhibitor on renal function in unanaesthetized sheep.
Topics: Animals; Benzofurans; Female; Kidney; Renin; Sheep; Sleep; Sodium; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Urodynamics | 1987 |
Beneficial effects of U-63,557A, a thromboxane synthetase inhibitor, in an ovine model of pregnancy-induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Pressure; Female; Hypertension; Kidney Function Tests; Platelet Count; Pregnancy; Pregnancy Complications, Cardiovascular; Sheep; Thromboxane B2; Thromboxane-A Synthase; Uterus | 1987 |
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Creatinine; Evaluation Studies as Topic; Ibuprofen; Imidazoles; Ischemia; Kidney; Kidney Tubular Necrosis, Acute; Male; Methacrylates; Pyridines; Rats; Thromboxane B2; Thromboxane-A Synthase | 1987 |
Effect of thromboxane synthetase inhibition on canine autogenous vein grafts.
Topics: Animals; Benzofurans; Blood Platelets; Carotid Arteries; Dogs; Female; Femoral Artery; Graft Occlusion, Vascular; Jugular Veins; Male; Thromboxane B2; Thromboxane-A Synthase; Time Factors; Tissue Preservation; Transplantation, Autologous | 1986 |
Effects of thromboxane synthase inhibition on vascular responsiveness in the in vivo rat mesentery.
Topics: Acrylates; Angiotensin II; Animals; Aorta, Abdominal; Benzofurans; Blood Platelets; Blood Pressure; Electric Stimulation; Imidazoles; Methacrylates; Norepinephrine; Rats; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance | 1985 |
Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Blood Platelets; Cyclic AMP; Dogs; Humans; Oxidoreductases; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1983 |
Beneficial effect of a thromboxane synthetase inhibitor in traumatic shock.
Topics: Animals; Benzofurans; Blood Pressure; Cathepsin D; Dose-Response Relationship, Drug; Lysosomes; Male; Myocardial Depressant Factor; Oxidoreductases; Prognosis; Rats; Rats, Inbred Strains; Shock, Traumatic; Thromboxane B2; Thromboxane-A Synthase | 1984 |
Sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate (U-63557A), a new, selective thromboxane synthase inhibitor: intravenous and oral pharmacokinetics in dogs and correlations with ex situ thromboxane B2 production.
Topics: Administration, Oral; Animals; Benzofurans; Chromatography, High Pressure Liquid; Dogs; Half-Life; Injections, Intravenous; Kinetics; Oxidoreductases; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1983 |
Acquired essential fatty acid depletion in the remnant kidney: amelioration with U-63557A.
Topics: Animals; Benzofurans; Dinoprostone; Fatty Acids; Fatty Acids, Essential; Kidney; Kidney Cortex; Male; Models, Biological; Nephrectomy; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Time Factors | 1994 |
Perfusion of the hypothalamic paraventricular nucleus with N-methyl-D-aspartate produces thromboxane A2 and centrally activates adrenomedullary outflow in rats.
Topics: Adrenal Medulla; Animals; Benzofurans; Catecholamines; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Paraventricular Hypothalamic Nucleus; Perfusion; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 2000 |
Thromboxane synthase regulates the migratory phenotype of human glioma cells.
Topics: Arachidonic Acids; Aspirin; Astrocytes; Benzofurans; Brain Neoplasms; Cell Adhesion; Cell Movement; Enzyme Induction; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; GTP-Binding Proteins; Humans; Imidazoles; Indomethacin; Lysine; Models, Biological; Neoplasm Proteins; Neoplastic Stem Cells; Oligodendroglia; Pentanoic Acids; Phenotype; Pyridines; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured | 1999 |
Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate.
Topics: Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Complement C5a; Enzyme Inhibitors; Hepatocytes; Liver; Male; Metabolic Clearance Rate; Oxazoles; Perfusion; Phenylacetates; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Thromboxane; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase | 2003 |
A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice.
Topics: Acetylcholine; Acetylcysteine; Aging; Animals; Antioxidants; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Catechin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Gene Expression Regulation, Enzymologic; Hydrazines; Indomethacin; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroarginine; Oxidation-Reduction; Reactive Oxygen Species; Receptors, Thromboxane A2, Prostaglandin H2; Renal Artery; RNA, Messenger; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasodilator Agents | 2007 |
Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta.
Topics: Adenosine; Animals; Aorta; Benzofurans; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Indomethacin; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitrobenzenes; Polymerase Chain Reaction; Pyrazoles; Pyridines; Receptor, Adenosine A3; Receptors, Thromboxane; RNA, Messenger; Signal Transduction; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction; Vasoconstrictor Agents | 2007 |