Compounds > furan

Page last updated: 2024-08-18

furan and malealdehyde

furan has been researched along with malealdehyde in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (5.88)	18.2507
2000's	8 (47.06)	29.6817
2010's	7 (41.18)	24.3611
2020's	1 (5.88)	2.80

Authors

Authors	Studies
Chen, LJ; Hecht, SS; Peterson, LA	1
Naruko, KC; Peterson, LA; Predecki, DP	1
Byrns, MC; Peterson, LA; Predecki, DP	1
Bohnert, T; Dedon, PC; Gingipalli, L	1
Byrns, MC; Peterson, LA; Vu, CC	1
Peterson, LA; Vu, CC	1
Cummings, ME; Matter, BA; Peterson, LA; Vu, CC	1
Brink, A; Kellert, M; Lutz, WK; Richter, I; Schlatter, J	1
Lu, D; Peterson, LA; Phillips, MB; Sullivan, MM	2
Lu, D; Peterson, LA	1
Appel, KE; Bakhiya, N	1
Dekant, W; Hamberger, C; Kellert, M; Mally, A; Schauer, UM	1
Gates, LA; Lu, D; Peterson, LA	1
Chen, F; Hu, X; Wang, E; Yuan, Y	1
Bandyopadhyay, D; Gates, LA; Grill, AE; Lu, D; Murphy, SE; Peterson, LA; Schmitt, T; Yuan, JM	1
Aguiar, A; Palmeira, CM; Rolo, AP; Silva, R; Sobral, AJFN; Teodoro, JS	1

Other Studies

17 other study(ies) available for furan and malealdehyde

Article	Year
Characterization of amino acid and glutathione adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan. Chemical research in toxicology, 1997, Volume: 10, Issue:8 Topics: Aldehydes; Amino Acids; Animals; Furans; Glutathione; Male; Microsomes, Liver; Rats; Rats, Inbred F344	1997
A reactive metabolite of furan, cis-2-butene-1,4-dial, is mutagenic in the Ames assay. Chemical research in toxicology, 2000, Volume: 13, Issue:7 Topics: Aldehydes; Dose-Response Relationship, Drug; Furans; Glutathione; Mutagenicity Tests; Mutagens; Mutation; Salmonella typhimurium	2000
Characterization of nucleoside adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan. Chemical research in toxicology, 2002, Volume: 15, Issue:3 Topics: Aldehydes; Animals; Carcinogens; Deoxyadenosines; Deoxyguanosine; DNA Adducts; Furans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; Molecular Structure; Nucleosides; Rats; Stereoisomerism	2002
Reaction of 2'-deoxyribonucleosides with cis- and trans-1,4-dioxo-2-butene. Biochemical and biophysical research communications, 2004, Oct-22, Volume: 323, Issue:3 Topics: Aldehydes; Deoxyribonucleosides; Deoxyribose; DNA Damage; Furans; Isomerism; Molecular Conformation; Oxidation-Reduction	2004
The formation of substituted 1,N6-etheno-2'-deoxyadenosine and 1,N2-etheno-2'-deoxyguanosine adducts by cis-2-butene-1,4-dial, a reactive metabolite of furan. Chemical research in toxicology, 2004, Volume: 17, Issue:12 Topics: Aldehydes; Deoxyadenosines; DNA Adducts; Furans	2004
Synthesis of a 2'-deoxyguanosine adduct of cis-2-butene-1,4-dial, a reactive metabolite of furan. Chemical research in toxicology, 2005, Volume: 18, Issue:6 Topics: Aldehydes; Deoxyguanosine; DNA; DNA Adducts; Furans	2005
Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial. Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:10 Topics: Aldehydes; Animals; Biological Assay; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Electrochemistry; Furans; Glutathione; Humans; In Vitro Techniques; Male; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred F344	2005
Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk+/- mouse lymphoma cells. Mutation research, 2008, Dec-08, Volume: 657, Issue:2 Topics: Aldehydes; Animals; Cell Line, Tumor; DNA; DNA Breaks; DNA Damage; Furans; Leukemia L5178; Mice; Mutagenicity Tests; Mutagens; Thymidine Kinase	2008
Degraded protein adducts of cis-2-butene-1,4-dial are urinary and hepatocyte metabolites of furan. Chemical research in toxicology, 2009, Volume: 22, Issue:6 Topics: Acetylcysteine; Aldehydes; Animals; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Furans; Glutathione; Hepatocytes; Humans; Lysine; Male; Rats	2009
Identification of furan metabolites derived from cysteine-cis-2-butene-1,4-dial-lysine cross-links. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Aldehydes; Animals; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Cysteine; Cytochrome P-450 Enzyme System; Furans; Lysine; Rats; Tandem Mass Spectrometry	2010
Toxicity and carcinogenicity of furan in human diet. Archives of toxicology, 2010, Volume: 84, Issue:7 Topics: Aldehydes; Alkenes; Animals; Carcinogens; Diet; Female; Furans; Humans; Infant; Infant Food; Mice; Neoplasms; Rats; Rats, Sprague-Dawley	2010
Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:10 Topics: Aldehydes; Animals; Bile; Bile Ducts; Biliary Tract Diseases; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Furans; Glutathione; Glycine; Male; Rats; Rats, Inbred F344; Tandem Mass Spectrometry	2010
Polyamines are traps for reactive intermediates in furan metabolism. Chemical research in toxicology, 2011, Nov-21, Volume: 24, Issue:11 Topics: Acetylcysteine; Aldehydes; Animals; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Environmental Pollution; Furans; Glutamine; Glutathione; Hepatocytes; Humans; Liver; Lysine; Mass Spectrometry; Ornithine; Oxidation-Reduction; Putrescine; Pyrroles; Rats; Spermidine	2011
Trapping of cis-2-butene-1,4-dial to measure furan metabolism in human liver microsomes by cytochrome P450 enzymes. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:3 Topics: Acetylcysteine; Aldehydes; Animals; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Furans; Glutathione; Humans; Lysine; Mice; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Rats; Tandem Mass Spectrometry	2012
Protective effects of apigenin against furan-induced toxicity in mice. Food & function, 2014, Volume: 5, Issue:8 Topics: Alanine Transaminase; Aldehydes; Animals; Antioxidants; Apigenin; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatinine; DNA Damage; Dose-Response Relationship, Drug; Furans; Glutathione; Glutathione Transferase; Interleukin-10; Interleukin-1beta; Interleukin-6; Kidney; Liver; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha	2014
Abundant Rodent Furan-Derived Urinary Metabolites Are Associated with Tobacco Smoke Exposure in Humans. Chemical research in toxicology, 2015, Jul-20, Volume: 28, Issue:7 Topics: Aldehydes; Animals; Biomarkers; Chromatography, High Pressure Liquid; Female; Furans; Humans; Male; Mice; Nicotiana; Rats; Rats, Inbred F344; Smoking; Tandem Mass Spectrometry	2015
Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product Toxicology mechanisms and methods, 2020, Volume: 30, Issue:7 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Triphosphate; Aldehydes; Animals; Cell Survival; Cells, Cultured; Coffee; Cooking; DNA Damage; Dose-Response Relationship, Drug; Furans; Hepatocytes; Hot Temperature; Humans; Oxidative Stress; Protein Carbamylation; Rats; Seeds; Species Specificity; Time Factors	2020