Page last updated: 2024-09-03

furamidine and topotecan

furamidine has been researched along with topotecan in 1 studies

Compound Research Comparison

Studies
(furamidine)
Trials
(furamidine)
Recent Studies (post-2010)
(furamidine)
Studies
(topotecan)
Trials
(topotecan)
Recent Studies (post-2010) (topotecan)
1081322,392626792

Protein Interaction Comparison

ProteinTaxonomyfuramidine (IC50)topotecan (IC50)
Cytochrome P450 3A4Homo sapiens (human)1.5211
DNA topoisomerase 1Homo sapiens (human)0.8525
DNA topoisomerase 2-alphaHomo sapiens (human)0.605
DNA topoisomerase 2-betaHomo sapiens (human)0.605
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.06
Multidrug and toxin extrusion protein 2Homo sapiens (human)8.6
Multidrug and toxin extrusion protein 1Homo sapiens (human)1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.17

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chepanova, AA; Kaledin, VI; Lavrik, OI; Leung, E; Leung, IKH; Luzina, OA; Nikolin, VP; Patel, J; Popova, NA; Reynisson, J; Salakhutdinov, NF; Sokolov, DN; Volcho, KP; Zafar, A; Zakharenko, AL; Zakharova, OD1

Other Studies

1 other study(ies) available for furamidine and topotecan

ArticleYear
Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models.
    European journal of medicinal chemistry, 2019, Jan-01, Volume: 161

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Quantum Theory; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topotecan

2019