furamidine has been researched along with topotecan in 1 studies
| Studies (furamidine) | Trials (furamidine) | Recent Studies (post-2010) (furamidine) | Studies (topotecan) | Trials (topotecan) | Recent Studies (post-2010) (topotecan) |
|---|---|---|---|---|---|
| 108 | 1 | 32 | 2,392 | 626 | 792 |
| Protein | Taxonomy | furamidine (IC50) | topotecan (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 1.5211 | |
| DNA topoisomerase 1 | Homo sapiens (human) | 0.8525 | |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | 0.605 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.605 | |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | 0.06 | |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | 8.6 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 1.3 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 0.17 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chepanova, AA; Kaledin, VI; Lavrik, OI; Leung, E; Leung, IKH; Luzina, OA; Nikolin, VP; Patel, J; Popova, NA; Reynisson, J; Salakhutdinov, NF; Sokolov, DN; Volcho, KP; Zafar, A; Zakharenko, AL; Zakharova, OD | 1 |
1 other study(ies) available for furamidine and topotecan
| Article | Year |
|---|---|
Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Phosphoric Diester Hydrolases; Quantum Theory; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topotecan | 2019 |