Page last updated: 2024-09-03

furamidine and n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine

furamidine has been researched along with n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine in 1 studies

Compound Research Comparison

Studies (furamidine)	Trials (furamidine)	Recent Studies (post-2010) (furamidine)	Studies (n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine)	Trials (n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine)	Recent Studies (post-2010) (n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine)
108	1	32	81	0	37

Protein Interaction Comparison

Protein	Taxonomy	n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine (IC50)
Cytochrome P450 1A2	Homo sapiens (human)	0.461
Cytochrome P450 3A4	Homo sapiens (human)	0.1
Cytochrome P450 2D6	Homo sapiens (human)	0.1
Cytochrome P450 2C9	Homo sapiens (human)	2.935
Cytochrome P450 2C19	Homo sapiens (human)	0.272
Prostaglandin G/H synthase 2	Ovis aries (sheep)	2.3

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bridges, AS; Hall, JE; Kornbluth, S; Paine, MF; Tidwell, RR; Wang, MZ; Wu, JQ; Zeldin, DC	1

Other Studies

1 other study(ies) available for furamidine and n-hydroxy-n'-(4-butyl-2-methylphenyl)formamidine

Article	Year
Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11 Topics: Amidines; Antibodies; Antiparasitic Agents; Arachidonic Acid; Benzamidines; Benzoflavones; Butyrophenones; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Intestinal Mucosa; Intestines; Kinetics; Methylation; Microsomes; Oxygenases; Piperidines; Prodrugs; Recombinant Proteins; Stereoisomerism	2007

Article

Year

Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.

Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11

Topics: Amidines; Antibodies; Antiparasitic Agents; Arachidonic Acid; Benzamidines; Benzoflavones; Butyrophenones; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Intestinal Mucosa; Intestines; Kinetics; Methylation; Microsomes; Oxygenases; Piperidines; Prodrugs; Recombinant Proteins; Stereoisomerism

2007