Page last updated: 2024-08-26

fulvestrant and pyrroles

fulvestrant has been researched along with pyrroles in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's5 (45.45)2.80

Authors

AuthorsStudies
Bland, KI; Filardo, EJ; Frackelton, AR; Quinn, JA1
Dai, A; Hashimura, K; Komesaroff, PA; Ling, S; Little, PJ; Liu, JP; Sudhir, K; Williams, MR1
Alper, RH; Mize, AL1
Campbell, H; Davies, BR; Dowsett, M; Gao, Q; Guest, SK; Johnston, S; Liccardi, G; Marangoni, E; Martin, LA; Pancholi, S; Polanska, UM; Rani, A; Ribas, R; Simigdala, N; Thuleau, A1
Chandrasekaran, G; Kumar, D; Kumar, T; Mahobiya, A; Parida, S; Rungsung, S; Singh, TU1
Alchami, F; Bale, C; Bezecny, P; Butler, R; Carucci, M; Casbard, A; Cox, C; Foxley, A; Howell, SJ; Joffe, J; Jones, RH; Madden, TA; Moon, S; Twelves, C; Venkitaraman, R; Waters, S1
Abraham, J; Baird, RD; Bliss, JM; Braybrooke, JP; Bye, H; Cameron, D; Cutts, R; Gevensleben, H; Hubank, M; Kernaghan, S; Kilburn, LS; Kingston, B; Macpherson, IR; Martin, S; Moretti, L; Oikonomidou, O; Randle, K; Rea, D; Ring, A; Roylance, R; Shaaban, A; Snowdon, C; Stephens, P; Turner, NC; Tuthill, M; Wardley, AM; Wilkinson, K; Winter, MC1
Andrikopoulou, A; Chatzinikolaou, S; Dimopoulos, MA; Kaparelou, M; Liontos, M; Panourgias, E; Zagouri, F1
Bale, C; Bezecny, P; Butler, R; Carucci, M; Casbard, A; de Bruin, EC; Foxley, A; Howell, SJ; Ingarfield, K; Jones, RH; Meissner, M; Moon, S; Morgan, S; Schiavon, G; Twelves, C; Venkitaraman, R; Waters, S1

Reviews

1 review(s) available for fulvestrant and pyrroles

ArticleYear
"The emerging role of capivasertib in breast cancer".
    Breast (Edinburgh, Scotland), 2022, Volume: 63

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Fulvestrant; Humans; Mutation; Paclitaxel; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, ErbB-2

2022

Trials

3 trial(s) available for fulvestrant and pyrroles

ArticleYear
Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial.
    The Lancet. Oncology, 2020, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Double-Blind Method; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Fulvestrant; Humans; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Pyrimidines; Pyrroles; Receptors, Estrogen; Salvage Therapy; Survival Rate

2020
Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial.
    The Lancet. Oncology, 2020, Volume: 21, Issue:10

    Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Circulating Tumor DNA; Estrogen Receptor alpha; Female; Fulvestrant; Genotype; Humans; Middle Aged; Molecular Targeted Therapy; Mutation; Prospective Studies; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrimidines; Pyrroles; Quinolines; Receptor, ErbB-2; Receptors, Estrogen; Treatment Outcome

2020
Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomar
    The Lancet. Oncology, 2022, Volume: 23, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Female; Fulvestrant; Humans; Neoplasm Recurrence, Local; Phosphatidylinositol 3-Kinases; Progression-Free Survival; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, ErbB-2; Receptors, Estrogen

2022

Other Studies

7 other study(ies) available for fulvestrant and pyrroles

ArticleYear
Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis.
    Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:1

    Topics: Adenylyl Cyclases; Breast Neoplasms; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; ErbB Receptors; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Humans; Indoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-raf; Pyrroles; Receptors, Cell Surface; Receptors, Estrogen; Receptors, G-Protein-Coupled; Tamoxifen; Tumor Cells, Cultured

2002
High glucose abolishes the antiproliferative effect of 17beta-estradiol in human vascular smooth muscle cells.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:4

    Topics: Becaplermin; Blotting, Western; Cell Division; Cells, Cultured; DNA; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Glucose; Humans; Mesylates; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins c-sis; Pyrroles

2002
Rapid uncoupling of serotonin-1A receptors in rat hippocampus by 17beta-estradiol in vitro requires protein kinases A and C.
    Neuroendocrinology, 2002, Volume: 76, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carbazoles; Cell Membrane; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Indoles; Naphthalenes; Ovariectomy; Phosphorylation; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Staurosporine

2002
AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:9

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cluster Analysis; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; Estradiol; Female; Fulvestrant; Gene Expression Profiling; Humans; Mice; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Pyrimidines; Pyrroles; Receptors, Estrogen; Signal Transduction; TOR Serine-Threonine Kinases; Transcriptional Activation; Xenograft Model Antitumor Assays

2015
Targeting Mutant AKT in Cancer.
    Cancer discovery, 2016, Volume: 6, Issue:1

    Topics: Clinical Trials, Phase I as Topic; Drug Synergism; Estradiol; Fulvestrant; Humans; Mutation; Neoplasms; Neoplastic Cells, Circulating; Precision Medicine; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Treatment Outcome

2016
Kaempferol-induces vasorelaxation via endothelium-independent pathways in rat isolated pulmonary artery.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:5

    Topics: Animals; Apamin; Barium Compounds; Calcium Chloride; Chlorides; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Fulvestrant; Glyburide; In Vitro Techniques; Indomethacin; Isoquinolines; Kaempferols; Male; Morpholines; NG-Nitroarginine Methyl Ester; Oxadiazoles; Peptides; Potassium; Pulmonary Artery; Pyrroles; Quinoxalines; Rats; Sulfonamides; Tetraethylammonium; Vasodilation; Vasodilator Agents

2018
Capivasertib Doubles PFS in Some Breast Cancers.
    Cancer discovery, 2023, 02-06, Volume: 13, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Fulvestrant; Humans; Pyrimidines; Pyrroles; Receptor, ErbB-2

2023