fulvestrant has been researched along with piperidines in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (29.41) | 18.2507 |
| 2000's | 9 (26.47) | 29.6817 |
| 2010's | 13 (38.24) | 24.3611 |
| 2020's | 2 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Fuchs-Young, R; Hale, L; Howe, S; Miles, R; Walker, C | 1 |
| Gradishar, WJ; Jordan, VC | 1 |
| Carver, JM; Lundeen, SG; McKean, ML; Winneker, RC | 1 |
| Cheskis, BJ; Karathanasis, S; Lyttle, CR | 1 |
| Logie, C; Nichols, M; Rientjes, JM; Stewart, AF | 1 |
| Catherino, WH; Jordan, VC; Levenson, AS | 1 |
| Belanger, A; Gauthier, S; Labrie, C; Labrie, F; Merand, Y; Poirier, D; Sanchez, R; Simard, J; Singh, SM | 1 |
| Lane, MV; Merchenthaler, I; Shughrue, PJ | 1 |
| Funder, JW; Logie, C; Myles, K; Nichols, M; Stewart, AF | 1 |
| Jordan, VC; Liu, H; Schafer, JI; Tonetti, DA | 1 |
| Annable, T; Collins, KI; Frost, P; Greenberger, LM; Komm, BS; Lyttle, CR; Miller, CP; Satyaswaroop, PG; Zhang, Y | 1 |
| Elkak, AE; Mokbel, K | 1 |
| Chan, S | 1 |
| Cano, A; García-Martínez, MC; Hermenegildo, C; Tarín, JJ | 1 |
| Briand, P; Jensen, J; Kitlen, JW; Labrie, F; Lykkesfeldt, AE | 1 |
| Christensen, GL; Freddie, CT; Lykkesfeldt, AE | 1 |
| Griekspoor, A; Michalides, R; Neefjes, J; Rondaij, M; Verwoerd, D; Zwart, W | 1 |
| Leaños-Castañeda, O; Van Der Kraak, G | 1 |
| Davis, AM; Kohl, JA; Mao, J; Naz, B; Rosenfeld, CS | 1 |
| Amisten, S; Balhuizen, A; Kumar, R; Lundquist, I; Salehi, A | 1 |
| Bangaru, ML; Ben-Jonathan, N; Chen, S; Dunckley, JA; Kansra, S; Sneade, L | 1 |
| Mayer, GD; Notch, EG | 1 |
| Gubish, CT; Henry, C; Rothstein, ME; Siegfried, JM; Stabile, LP | 1 |
| Belleau, P; Calvo, E; Labrie, F; Luu-The, V; Martel, C | 1 |
| Al-Nakkash, L | 1 |
| Kajta, M; Krzeptowski, W; Lason, W; Lenartowicz, M; Litwa, E; Rzemieniec, J; Wojtowicz, AK | 1 |
| Acaz-Fonseca, E; Bellini, MJ; Garcia-Segura, LM; Grassi, D; Panzica, G | 1 |
| Dowsett, M; Gao, Q; Isacke, CM; Mackay, A; Martin, LA; Morandi, A; Pancholi, S; Plaza-Menacho, I; Robertson, D; Zvelebil, M | 1 |
| Califaretti, N; Chia, SK; Clemons, MJ; Cochrane, B; Dent, RA; Levine, MN; Parpia, S; Pond, GR; Pritchard, KI; Rayson, D; Robidoux, A; Song, X; Warr, D | 1 |
| Dehghan, F; Muniandy, S; Salleh, N; Yusof, A | 1 |
| Bueno-Betí, C; Gironacci, MM; Hermenegildo, C; Lázaro-Franco, M; Mompeón, A; Monsalve, E; Novella, S; Pérez-Cremades, D; Vidal-Gómez, X | 1 |
| Lücking, U; Sirvent, JA | 1 |
| Cheng, J; Feng, J; Hu, X; Li, W; Liu, Q; Liu, Y; Ouyang, Q; Pan, Y; Shi, Y; Sun, T; Teng, Y; Tong, Z; Wang, X; Wang, Y; Wu, F; Wu, X; Xie, W; Xu, B; Yan, M; Yan, P; Yan, X; Yin, Y; Zhang, P; Zhang, Q; Zhu, X; Zou, J | 1 |
| Eisner, JR; Lerner, LM; Michmerhuizen, AR; Pesch, AM; Pierce, LJ; Rae, JM; Schwartz, R; Speers, CW; Ward, C; Wilder-Romans, K; Zhang, A | 1 |
3 review(s) available for fulvestrant and piperidines
| Article | Year |
|---|---|
Clinical potential of new antiestrogens.
Topics: Antineoplastic Agents, Hormonal; Bone Density; Drugs, Investigational; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride; Tamoxifen; Toremifene | 1997 |
Pure antiestrogens and breast cancer.
Topics: Antineoplastic Agents, Hormonal; Benzopyrans; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Piperidines; Polyunsaturated Alkamides; Propionates | 2001 |
A review of selective estrogen receptor modulators in the treatment of breast and endometrial cancer.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Endometrial Neoplasms; Estradiol; Female; Fulvestrant; Humans; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes | 2002 |
2 trial(s) available for fulvestrant and piperidines
| Article | Year |
|---|---|
Randomised, phase II, placebo-controlled, trial of fulvestrant plus vandetanib in postmenopausal women with bone only or bone predominant, hormone-receptor-positive metastatic breast cancer (MBC): the OCOG ZAMBONEY study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Collagen Type I; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Peptides; Piperidines; Postmenopause; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome | 2014 |
Dalpiciclib or placebo plus fulvestrant in hormone receptor-positive and HER2-negative advanced breast cancer: a randomized, phase 3 trial.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Proliferation; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Disease Progression; Double-Blind Method; Female; Fulvestrant; Humans; Middle Aged; Piperidines; Placebos; Progression-Free Survival; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone | 2021 |
29 other study(ies) available for fulvestrant and piperidines
| Article | Year |
|---|---|
Inhibition of estrogen-stimulated growth of uterine leiomyomas by selective estrogen receptor modulators.
Topics: Animals; Cell Division; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Leiomyoma; Phenotype; Piperidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured; Uterine Neoplasms | 1996 |
Characterization of the ovariectomized rat model for the evaluation of estrogen effects on plasma cholesterol levels.
Topics: Animals; Cholesterol; Dexamethasone; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Fulvestrant; Lipids; Ovariectomy; Piperidines; Progesterone; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus | 1997 |
Estrogen receptor ligands modulate its interaction with DNA.
Topics: DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Fulvestrant; Humans; Ligands; Piperidines; Protein Binding; Raloxifene Hydrochloride; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Tamoxifen; Transcription Factors | 1997 |
FLP recombinase/estrogen receptor fusion proteins require the receptor D domain for responsiveness to antagonists, but not agonists.
Topics: Amino Acid Sequence; Bacterial Outer Membrane Proteins; Diethylstilbestrol; DNA Nucleotidyltransferases; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens, Non-Steroidal; Fulvestrant; Hexestrol; HSP90 Heat-Shock Proteins; Humans; Ligands; Molecular Sequence Data; Nafoxidine; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Tamoxifen; Time Factors; Yeasts | 1997 |
Estrogenic activity is increased for an antiestrogen by a natural mutation of the estrogen receptor.
Topics: Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mutation; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; RNA, Messenger; RNA, Neoplasm; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1997 |
Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH-toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human endometrial adenocarcinoma Ishikawa cells.
Topics: Adenocarcinoma; Alkaline Phosphatase; Benzopyrans; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasm Proteins; Piperidines; Propionates; Raloxifene Hydrochloride; Tamoxifen; Toremifene; Tumor Cells, Cultured | 1997 |
Regulation of progesterone receptor messenger ribonucleic acid in the rat medial preoptic nucleus by estrogenic and antiestrogenic compounds: an in situ hybridization study.
Topics: Animals; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; In Situ Hybridization; Piperidines; Preoptic Area; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; RNA, Messenger; Sensitivity and Specificity; Tamoxifen; Time Factors | 1997 |
Positive and negative discrimination of estrogen receptor agonists and antagonists using site-specific DNA recombinase fusion proteins.
Topics: Diethylstilbestrol; Dimerization; DNA Nucleotidyltransferases; Estradiol; Estrogen Antagonists; Fulvestrant; Hexestrol; Humans; Mutation; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Tamoxifen | 1998 |
The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor.
Topics: Benzopyrans; Cell Division; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Piperidines; Propionates; Raloxifene Hydrochloride; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydrochloride (ERA-923), inhibits the growth of tamoxifen-sensitive and -resistant tumors and is devoid of uterotropic effects in mice and rats.
Topics: Animals; Binding, Competitive; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Indoles; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Organ Size; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sensitivity and Specificity; Tamoxifen; Time Factors; Tumor Cells, Cultured; Uterus; Xenograft Model Antitumor Assays | 2001 |
Estradiol reduces F2alpha-isoprostane production in cultured human endothelial cells.
Topics: Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Infant, Newborn; Isoprostanes; Male; Medroxyprogesterone Acetate; Piperidines; Progesterone; Progesterone Congeners; Umbilical Veins | 2002 |
Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium.
Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Fulvestrant; Humans; Ligands; Membrane Proteins; Piperidines; Presenilin-2; Protein Binding; Receptors, Estrogen; RNA, Messenger; Tamoxifen; Time Factors; Tumor Cells, Cultured | 2003 |
A new MCF-7 breast cancer cell line resistant to the arzoxifene metabolite desmethylarzoxifene.
Topics: Breast Neoplasms; Cathepsin D; Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Fulvestrant; Histone Acetyltransferases; Humans; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Piperidines; Proto-Oncogene Proteins c-bcl-2; Receptors, Progesterone; Repressor Proteins; RNA, Messenger; Tamoxifen; Thiophenes; Transcription Factors | 2004 |
Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.
Topics: Bacterial Proteins; Cell Line, Tumor; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Fluorescence Resonance Energy Transfer; Fulvestrant; Humans; Luminescent Proteins; Models, Biological; Models, Chemical; Mutation; Piperidines; Tamoxifen; Transcriptional Activation | 2007 |
Functional characterization of estrogen receptor subtypes, ERalpha and ERbeta, mediating vitellogenin production in the liver of rainbow trout.
Topics: Animals; Binding, Competitive; Biological Assay; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Hepatocytes; Ligands; Nitriles; Oncorhynchus mykiss; Phenols; Piperidines; Propionates; Pyrazoles; Radioligand Assay; Tamoxifen; Vitellogenins | 2007 |
Comparative effects of estradiol, methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus.
Topics: Animals; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Female; Fulvestrant; Gene Expression; Mice; Oligonucleotide Array Sequence Analysis; Ovariectomy; Piperidines; Pyrazoles; Raloxifene Hydrochloride; Reverse Transcriptase Polymerase Chain Reaction; Uterus | 2008 |
Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice.
Topics: Animals; Apoptosis; Cyclic AMP; Cytokines; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Gene Expression Regulation; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Pancreatic Hormones; Piperidines; Receptors, Estrogen; Receptors, G-Protein-Coupled; RNA, Messenger | 2010 |
Selective estrogen receptor down-regulator and selective estrogen receptor modulators differentially regulate lactotroph proliferation.
Topics: Animals; Cell Line; Cell Proliferation; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Fulvestrant; Lactotrophs; Piperidines; Prolactin; Pyrazoles; Rats; Selective Estrogen Receptor Modulators | 2010 |
Efficacy of pharmacological estrogen receptor antagonists in blocking activation of zebrafish estrogen receptors.
Topics: Animals; Cell Line, Tumor; Estradiol; Ethinyl Estradiol; Fulvestrant; Humans; Piperidines; Pyrazoles; Pyrimidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Zebrafish | 2011 |
Combining the multitargeted tyrosine kinase inhibitor vandetanib with the antiestrogen fulvestrant enhances its antitumor effect in non-small cell lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Fluorescent Antibody Technique; Fulvestrant; Humans; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, SCID; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-3 | 2012 |
Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland.
Topics: Animals; Cluster Analysis; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Regulation; Genes; Genes, Neoplasm; Mammary Glands, Animal; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Transcription, Genetic; Transcriptome | 2012 |
Genistein stimulates jejunal chloride secretion via sex-dependent, estrogen receptor or adenylate cyclase mechanisms.
Topics: Actins; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Enzyme Activators; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Genistein; Imines; Intestinal Secretions; Jejunum; Male; Mice; Mice, Inbred C57BL; Orchiectomy; Phytoestrogens; Piperidines; Pyrazoles; Sex Characteristics; Signal Transduction | 2012 |
The key involvement of estrogen receptor β and G-protein-coupled receptor 30 in the neuroprotective action of daidzein.
Topics: Animals; Apoptosis; Benzodioxoles; Caspase 3; Cells, Cultured; Cerebellum; Estradiol; Estrogen Receptor beta; Fulvestrant; Glutamic Acid; Hippocampus; Isoflavones; Membrane Potential, Mitochondrial; Mice; Neocortex; Neurons; Neuroprotective Agents; Phosphorylation; Piperidines; Pyrazoles; Quinolines; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction | 2013 |
Estradiol and testosterone regulate arginine-vasopressin expression in SH-SY5Y human female neuroblastoma cells through estrogen receptors-α and -β.
Topics: Arginine Vasopressin; Cell Line, Tumor; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Nitriles; Phenols; Piperidines; Pyrazoles; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Testosterone | 2013 |
GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors.
Topics: Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Cohort Studies; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glial Cell Line-Derived Neurotrophic Factor; Humans; Kaplan-Meier Estimate; Letrozole; MCF-7 Cells; Middle Aged; Nitriles; Oligonucleotide Array Sequence Analysis; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-ret; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Triazoles | 2013 |
Estrogen receptor (ER)-α, β and progesterone receptor (PR) mediates changes in relaxin receptor (RXFP1 and RXFP2) expression and passive range of motion of rats' knee.
Topics: Animals; Estradiol; Female; Fulvestrant; Hindlimb; Male; Mifepristone; Piperidines; Progesterone; Pyrazoles; Pyrimidines; Range of Motion, Articular; Rats; Rats, Inbred WKY; Receptors, G-Protein-Coupled; Receptors, Peptide; Steroids | 2015 |
Estradiol, acting through ERα, induces endothelial non-classic renin-angiotensin system increasing angiotensin 1-7 production.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Fulvestrant; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Piperidines; Pyrazoles | 2016 |
Novel Pieces for the Emerging Picture of Sulfoximines in Drug Discovery: Synthesis and Evaluation of Sulfoximine Analogues of Marketed Drugs and Advanced Clinical Candidates.
Topics: Aminopyridines; Ataxia Telangiectasia Mutated Proteins; Cyclin-Dependent Kinases; Drug Design; Estradiol; Fulvestrant; Imatinib Mesylate; Piperazines; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyridines; Sulfoxides; Vardenafil Dihydrochloride | 2017 |
Androgen and oestrogen receptor co-expression determines the efficacy of hormone receptor-mediated radiosensitisation in breast cancer.
Topics: Androgen Receptor Antagonists; Androgens; Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Naphthalenes; Piperidines; Pyrrolidines; Radiation Tolerance; Receptors, Androgen; Receptors, Estrogen; Tamoxifen; Thiazoles; Triazoles | 2022 |