Page last updated: 2024-08-26

fulvestrant and methoxychlor

fulvestrant has been researched along with methoxychlor in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akingbemi, BT; Ge, RS; Gunsalus, GL; Hardy, MP; Klinefelter, GR1
Gore, AC1
Flaws, JA; Miller, KP; Symonds, DA; Tomic, D2
Akgul, Y; Derk, RC; Meighan, T; Murono, EP; Rao, KM1
Bagnell, CA; Chen, JC; Harvey, CN; Uzumcu, M1
Ciereszko, RE; Czaja, E; Grzesiak, M; Knapczyk-Stwora, K; Koziorowski, M; Slomczynska, M1

Trials

1 trial(s) available for fulvestrant and methoxychlor

ArticleYear
The impact of sex steroid agonists and antagonists on folliculogenesis in the neonatal porcine ovary via cell proliferation and apoptosis.
    Theriogenology, 2018, Volume: 113

    Topics: Androgen Antagonists; Androgens; Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Estradiol; Estrogen Receptor Antagonists; Female; Flutamide; Fulvestrant; Granulosa Cells; Insecticides; Methoxychlor; Ovarian Follicle; Phenols; Swine; Testosterone Propionate

2018

Other Studies

6 other study(ies) available for fulvestrant and methoxychlor

ArticleYear
A metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme.
    Biology of reproduction, 2000, Volume: 62, Issue:3

    Topics: Animals; Cell Differentiation; Cell Survival; Cholesterol Side-Chain Cleavage Enzyme; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Fulvestrant; Leydig Cells; Luteinizing Hormone; Male; Methoxychlor; Phenols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Testosterone

2000
Organochlorine pesticides directly regulate gonadotropin-releasing hormone gene expression and biosynthesis in the GT1-7 hypothalamic cell line.
    Molecular and cellular endocrinology, 2002, Jun-28, Volume: 192, Issue:1-2

    Topics: Animals; Cell Line, Transformed; Cell Nucleus; Chlorpyrifos; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor Modulators; Estrogens, Non-Steroidal; Fulvestrant; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Hypothalamus; Insecticides; Methoxychlor; Mice; Neurons; Receptors, Estrogen; RNA, Messenger; Transcription, Genetic

2002
Methoxychlor induces proliferation of the mouse ovarian surface epithelium.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 83, Issue:2

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Count; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Cyclin D2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Epithelium; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Insecticides; Methoxychlor; Mice; Mice, Inbred Strains; Ovary; Phenols; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2

2005
Effect of methoxychlor and estradiol on cytochrome p450 enzymes in the mouse ovarian surface epithelium.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 89, Issue:2

    Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Endocrine Disruptors; Enzyme Induction; Epithelial Cells; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Metabolic Detoxication, Phase I; Methoxychlor; Mice; Mice, Inbred Strains; Ovary; Polymerase Chain Reaction

2006
The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells.
    Reproductive toxicology (Elmsford, N.Y.), 2008, Volume: 25, Issue:1

    Topics: Androgen Antagonists; Animals; Benzhydryl Compounds; Catalytic Domain; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Fulvestrant; Gene Expression Regulation, Enzymologic; Gonadotropins, Equine; Methoxychlor; Ovary; Oxazoles; Phenols; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen; RNA, Messenger

2008
Methoxychlor and its metabolite HPTE inhibit cAMP production and expression of estrogen receptors α and β in the rat granulosa cell in vitro.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 51

    Topics: Animals; Cells, Cultured; Cyclic AMP; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Follicle Stimulating Hormone; Fulvestrant; Granulosa Cells; Insecticides; Methoxychlor; Nitriles; Phenols; Pyrazoles; Pyrimidines; Rats, Sprague-Dawley; RNA, Messenger

2015