Compounds > fulvestrant
Page last updated: 2024-08-26

fulvestrant and gw 7604

fulvestrant has been researched along with gw 7604 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Aparicio, A; Bonnefous, C; Brigham, D; Darimont, B; Douglas, K; Govek, S; Grillot, K; Hager, JH; Heyman, R; Joseph, JD; Julien, J; Kahraman, M; Kaufman, J; Lai, A; Lee, KJ; Lu, N; Moon, MJ; Nagasawa, J; Prudente, R; Qian, J; Rix, PJ; Sensintaffar, J; Shao, G; Smith, ND1
Andrews, DM; Ballard, P; Bradbury, RH; Buttar, D; Callis, RJ; Currie, GS; Curwen, JO; Davies, CD; de Almeida, C; De Savi, C; Donald, CS; Feron, LJ; Gingell, H; Glossop, SC; Hayter, BR; Hussain, S; Karoutchi, G; Lamont, SG; MacFaul, P; Moss, TA; Norman, RA; Pearson, SE; Rabow, AA; Tonge, M; Walker, GE; Weir, HM; Wilson, Z1
Abrams, T; Baird, J; Burks, HE; Fekete, A; Hamann, LG; Kim, S; Kirby, CA; Lombardo, F; Loo, A; Lubicka, D; Macchi, K; McDonnell, DP; Mishina, Y; Norris, JD; Nunez, J; Peukert, S; Saran, C; Sun, Y; Thomsen, NM; Wang, C; Wang, J1
Aparicio, AM; Bonnefous, C; Darimont, BD; Douglas, KL; Govek, SP; Grillot, KL; Hager, JH; Joseph, JD; Julien, JD; Kahraman, M; Kaufman, JA; Lai, AG; Lee, KJ; Lu, N; Moon, MJ; Nagasawa, JY; Prudente, RY; Rix, PJ; Sensintaffar, J; Smith, ND1
Baecker, D; Gaggia, F; Gust, R; Kalchschmid, C; Knox, A; Manzl, C; Schuster, D1
Christensen, DJ; Fowlkes, DM; McDonnell, DP; Nagel, SC; Norris, JD; Paige, LA; Wijayaratne, AL1

Other Studies

6 other study(ies) available for fulvestrant and gw 7604

ArticleYear
Identification of GDC-0810 (ARN-810), an Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) that Demonstrates Robust Activity in Tamoxifen-Resistant Breast Cancer Xenografts.
    Journal of medicinal chemistry, 2015, Jun-25, Volume: 58, Issue:12

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; Dogs; Drug Discovery; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Heterografts; Humans; Mice; Proteolysis; Rats; Selective Estrogen Receptor Modulators; Small Molecule Libraries; Tamoxifen

2015
Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregu
    Journal of medicinal chemistry, 2015, Oct-22, Volume: 58, Issue:20

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cinnamates; Clinical Trials, Phase I as Topic; Down-Regulation; Drug Design; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Humans; Indoles; Injections, Intramuscular; X-Ray Diffraction

2015
Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERĪ±+ Breast Cancer.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Acrylates; Administration, Oral; Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Dogs; Drug Discovery; Estrogen Receptor alpha; Female; Humans; MCF-7 Cells; Mice, Inbred C57BL; Molecular Docking Simulation; Proteolysis; Tetrahydroisoquinolines

2017
Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen-resistant breast cancer xenograft.
    Bioorganic & medicinal chemistry letters, 2019, 02-01, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cinnamates; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Indazoles; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Tamoxifen

2019
Development of bivalent triarylalkene- and cyclofenil-derived dual estrogen receptor antagonists and downregulators.
    European journal of medicinal chemistry, 2020, Apr-15, Volume: 192

    Topics: Alkenes; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cyclofenil; Dose-Response Relationship, Drug; Down-Regulation; Drug Development; Estrogen Receptor Antagonists; Humans; Molecular Structure; Receptors, Estrogen; Structure-Activity Relationship

2020
Comparative analyses of mechanistic differences among antiestrogens.
    Endocrinology, 1999, Volume: 140, Issue:12

    Topics: Blood Proteins; Breast Neoplasms; Cell Division; Cinnamates; Drug Stability; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Fulvestrant; Gene Expression; Humans; Protein Binding; Protein Conformation; Raloxifene Hydrochloride; Receptors, Estrogen; Stilbenes; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured

1999