Page last updated: 2024-08-26

fulvestrant and ethinyl estradiol

fulvestrant has been researched along with ethinyl estradiol in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (9.38)18.2507
2000's18 (56.25)29.6817
2010's10 (31.25)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Adrian, MD; Bryant, HU; Dodge, JA; Lugar, CW; Magee, D; Shetler, P1
Bellavance, E; Luu-The, V; Poirier, D1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Cao, Y; Guo, B; Kong, D; Lu, Z; Meng, X; Yang, Y; Zhang, D1
Carver, JM; Lundeen, SG; McKean, ML; Winneker, RC1
Cheskis, BJ; Karathanasis, S; Lyttle, CR1
Chen, J; Lavigne, JA; Li, Y; Trush, MA; Yager, JD1
Bean, JS; Bensch, WR; Cox, DA; Cullinan, GJ; Fahey, KJ; Kauffman, RF1
Mall, P; Prifti, S; Rabe, T; Strowitzki, T1
Loft, S; Wellejus, A1
Bennetau-Pelissero, C; Kaushik, SJ; Latonnelle, K; Le Menn, F1
Hara, T; Noda, S; Sawaki, M; Takatsuki, M; Wada, T; Yamasaki, K1
Addo, S; Laight, A; Yates, RA1
Ankley, GT; Hornung, MW; Schmieder, PK1
Mall, P; Prifti, S; Rabe, T1
Fujii, S; Itoh, H; Kakui, K; Korita, D; Miyamaoto, Y; Nakao, K; Sagawa, N; Saito, Y; Takemura, M; Yura, S1
Biggemann, F; Greven, J; Schlattjan, JH1
Degen, GH; Diel, P; Hertrampf, T; Schmidt, S; Seibel, J; Vollmer, G1
Birkenes, B; Dahm, AE; Iversen, N; Ree, AH; Sandset, PM1
Ashizawa, K; Fukuhara, T; Gohma, H; Katayama, S; Nagai, K; Nakada, T; Narumi, K; Tatemoto, H; Tsuzuki, Y1
Alfinito, PD; Atherton, J; Chen, X; Cosmi, S; Deecher, DC1
Mayer, GD; Notch, EG2
Cardon, MC; Hartig, PC; Rider, CV; Wilson, VS1
Davis, TL; Modi, N; Nagler, JJ; Schultz, I; Vijayan, MM1
Cleuren, AC; De Visser, YP; Reitsma, PH; Van der Linden, IK; Van Vlijmen, BJ; Wagenaar, GT1
Brion, F; Chadili, E; Combarnous, Y; Hinfray, N; Kah, O; Le Page, Y; Porcher, JM; Vosges, M1
Hoffmann, F; Kloas, W1
Arias, A; Banchio, C; Catania, VA; Mottino, AD; Rigalli, JP; Ruiz, ML; Villanueva, S; Vore, M1
Estrada-Camarena, E; López-Rubalcava, C; Vega-Rivera, NM1
Carroll, KJ; Cortes, M; Cutting, CC; Dovey, MC; Esain, V; Frechette, GM; Garnaas, MK; Goessling, W; Gorelick, DA; Halpern, ME; Harris, JM; Kwan, W; Lawson, ND; Liu, SY; Nissim, S; North, TE1
Castro, LF; Ferreira, N; Lopes, C; Madureira, TV; Malhão, F; Pinheiro, I; Rocha, E; Urbatzka, R1

Trials

1 trial(s) available for fulvestrant and ethinyl estradiol

ArticleYear
A phase I trial to assess the pharmacology of the new oestrogen receptor antagonist fulvestrant on the endometrium in healthy postmenopausal volunteers.
    British journal of cancer, 2002, Dec-02, Volume: 87, Issue:12

    Topics: Double-Blind Method; Drug Combinations; Endometrium; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Ethinyl Estradiol; Female; Fulvestrant; Humans; Middle Aged; Postmenopause; Quality of Life; Safety

2002

Other Studies

31 other study(ies) available for fulvestrant and ethinyl estradiol

ArticleYear
B-ring unsaturated estrogens: biological evaluation of 17alpha-Dihydroequilein and novel B-Nor-6-thiaequilenins as tissue selective estrogens.
    Bioorganic & medicinal chemistry letters, 2003, Dec-15, Volume: 13, Issue:24

    Topics: Animals; Equilin; Estradiol Congeners; Female; Models, Molecular; Molecular Conformation; Organ Size; Ovariectomy; Rats; Stereoisomerism; Structure-Activity Relationship; Uterus

2003
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Discovery of Thieno[2,3-
    Journal of medicinal chemistry, 2022, 04-14, Volume: 65, Issue:7

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogen Receptor alpha; Female; Humans; Indazoles; MCF-7 Cells; Mice; Receptors, Estrogen; Thiophenes

2022
Characterization of the ovariectomized rat model for the evaluation of estrogen effects on plasma cholesterol levels.
    Endocrinology, 1997, Volume: 138, Issue:4

    Topics: Animals; Cholesterol; Dexamethasone; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Fulvestrant; Lipids; Ovariectomy; Piperidines; Progesterone; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1997
Estrogen receptor ligands modulate its interaction with DNA.
    The Journal of biological chemistry, 1997, Apr-25, Volume: 272, Issue:17

    Topics: DNA-Binding Proteins; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Fulvestrant; Humans; Ligands; Piperidines; Protein Binding; Raloxifene Hydrochloride; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Tamoxifen; Transcription Factors

1997
Increased mitochondrial superoxide production in rat liver mitochondria, rat hepatocytes, and HepG2 cells following ethinyl estradiol treatment.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 51, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cells, Cultured; Estradiol; Estradiol Congeners; Estrogen Receptor Modulators; Ethinyl Estradiol; Fulvestrant; Glutathione; Liver; Liver Neoplasms; Male; Mitochondria, Liver; Rats; Rats, Inbred F344; Superoxides; Tumor Cells, Cultured

1999
Raloxifene and estrogen inhibit neointimal thickening after balloon injury in the carotid artery of male and ovariectomized female rats.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:4

    Topics: Animals; Carotid Artery Injuries; Catheterization; Cholesterol; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Female; Fulvestrant; Male; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley

2000
Synthetic estrogens-mediated activation of JNK intracellular signaling molecule.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2001, Volume: 15, Issue:2

    Topics: Blotting, Western; Cell Differentiation; Cell Division; Enzyme Activation; Epidermal Growth Factor; Estradiol; Estradiol Congeners; Ethinyl Estradiol; Fulvestrant; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Receptors, Estrogen; Signal Transduction; Tumor Cells, Cultured

2001
Receptor-mediated ethinylestradiol-induced oxidative DNA damage in rat testicular cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Age Factors; Animals; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Fulvestrant; Glutathione; Kidney; Liver; Male; Rats; Rats, Wistar; Receptors, Estrogen; Testis

2002
Effects of dietary phytoestrogens in vivo and in vitro in rainbow trout and Siberian sturgeon: interests and limits of the in vitro studies of interspecies differences.
    General and comparative endocrinology, 2002, Volume: 126, Issue:1

    Topics: Animals; Cells, Cultured; Diethylstilbestrol; Estradiol; Estrogen Antagonists; Estrogens, Non-Steroidal; Ethinyl Estradiol; Female; Fishes; Fulvestrant; Genistein; Hepatocytes; Isoflavones; Male; Phytoestrogens; Plant Preparations; Receptors, Estrogen; Species Specificity; Tamoxifen; Vitellogenins

2002
Immature uterotrophic assay of estrogenic compounds in rats given diets of different phytoestrogen content and the ovarian changes with ICI 182,780 or antide.
    Archives of toxicology, 2002, Volume: 76, Issue:11

    Topics: Animals; Benzhydryl Compounds; Body Weight; Dose-Response Relationship, Drug; Estradiol; Estrogens, Non-Steroidal; Ethinyl Estradiol; Female; Fulvestrant; Genistein; Isoflavones; Oligopeptides; Organ Size; Ovary; Phenols; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Uterus

2002
Induction of an estrogen-responsive reporter gene in rainbow trout hepatoma cells (RTH 149) at 11 or 18 degrees C.
    Environmental toxicology and chemistry, 2003, Volume: 22, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Estrogens; Ethinyl Estradiol; Fulvestrant; Gene Expression Regulation; Genes, Reporter; Oncorhynchus mykiss; Receptors, Estrogen; Temperature; Tetrahydronaphthalenes

2003
Synthetic estrogen-mediated activation of ERK 2 intracellular signaling molecule.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2003, Volume: 17, Issue:5

    Topics: Blotting, Western; Cell Division; Cells, Cultured; Epidermal Growth Factor; Estradiol; Estradiol Congeners; Ethinyl Estradiol; Female; Fulvestrant; Humans; Mitogen-Activated Protein Kinase 1

2003
Augmented endothelial nitric oxide synthase (eNOS) protein expression in human pregnant myometrium: possible involvement of eNOS promoter activation by estrogen via both estrogen receptor (ER)alpha and ERbeta.
    Molecular human reproduction, 2004, Volume: 10, Issue:2

    Topics: Adult; Blotting, Western; Cells, Cultured; Endometrium; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Ethinyl Estradiol; Female; Fulvestrant; Genes, Reporter; Humans; Immunochemistry; Myocytes, Smooth Muscle; Myometrium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norgestrel; Pregnancy; Promoter Regions, Genetic; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcriptional Activation; Transfection

2004
Gender differences in renal tubular taurocholate transport.
    Naunyn-Schmiedeberg's archives of pharmacology, 2005, Volume: 371, Issue:6

    Topics: Androgens; Animals; Buserelin; Cells, Cultured; Cholagogues and Choleretics; Estradiol; Estrogen Receptor Modulators; Estrogens; Ethinyl Estradiol; Female; Fertility Agents, Female; Fulvestrant; Kidney Tubules, Proximal; Male; Metabolic Clearance Rate; Organic Anion Transporters, Sodium-Dependent; Ovariectomy; Rats; Rats, Sprague-Dawley; Sex Factors; Symporters; Taurocholic Acid; Testosterone

2005
Hormonal activity of combinations of genistein, bisphenol A and 17beta-estradiol in the female Wistar rat.
    Archives of toxicology, 2006, Volume: 80, Issue:12

    Topics: Administration, Oral; Animals; Benzhydryl Compounds; Clusterin; Complement C3; Drug Interactions; Epithelial Cells; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Fulvestrant; Gene Expression; Genistein; Organ Size; Ovariectomy; Phenols; Phytoestrogens; Rats; Rats, Wistar; RNA, Messenger; Uterus; Vagina

2006
Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1.
    BMC cardiovascular disorders, 2006, Oct-09, Volume: 6

    Topics: Cells, Cultured; Down-Regulation; Endothelial Cells; Estradiol; Estrogen Receptor alpha; Ethinyl Estradiol; Fulvestrant; Humans; Lipoproteins; Raloxifene Hydrochloride; RNA, Messenger; Selective Estrogen Receptor Modulators

2006
The expression of Hedgehog genes (Ihh, Dhh) and Hedgehog target genes (Ptc1, Gli1, Coup-TfII) is affected by estrogenic stimuli in the uterus of immature female rats.
    Toxicology and applied pharmacology, 2006, Dec-15, Volume: 217, Issue:3

    Topics: Animals; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Fulvestrant; Gene Expression Regulation, Developmental; Hedgehog Proteins; Nitriles; Patched Receptors; Patched-1 Receptor; Phenols; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uterus

2006
ICI 182,780 penetrates brain and hypothalamic tissue and has functional effects in the brain after systemic dosing.
    Endocrinology, 2008, Volume: 149, Issue:10

    Topics: Animals; Blood-Brain Barrier; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Female; Fulvestrant; Hot Flashes; Hypothalamus; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Ovariectomy; Rats; Rats, Sprague-Dawley; Skin Temperature; Uterus

2008
17alpha-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells.
    Aquatic toxicology (Amsterdam, Netherlands), 2009, Dec-13, Volume: 95, Issue:4

    Topics: Animals; DNA Repair; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Fulvestrant; Liver; RNA, Messenger; Zebrafish

2009
Comparison of chemical binding to recombinant fathead minnow and human estrogen receptors alpha in whole cell and cell-free binding assays.
    Environmental toxicology and chemistry, 2009, Volume: 28, Issue:10

    Topics: Animals; Binding Sites; Binding, Competitive; Cadmium Chloride; Cell-Free System; Chlorocebus aethiops; COS Cells; Cyprinidae; Dibutyl Phthalate; Estradiol; Estrogen Receptor alpha; Ethinyl Estradiol; Fulvestrant; Humans; Phthalic Acids; Recombinant Proteins; Structure-Activity Relationship; Temperature; Zeranol

2009
Intracellular, not membrane, estrogen receptors control vitellogenin synthesis in the rainbow trout.
    General and comparative endocrinology, 2010, Jun-01, Volume: 167, Issue:2

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Female; Fulvestrant; Liver; Male; Molecular Sequence Data; Oncorhynchus mykiss; Receptors, Estrogen; Signal Transduction; Vitellogenins

2010
17α-Ethinylestradiol rapidly alters transcript levels of murine coagulation genes via estrogen receptor α.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:8

    Topics: Administration, Oral; Animals; Blood Coagulation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Ethinyl Estradiol; Female; Fulvestrant; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger; Time Factors

2010
17α-Ethinylestradiol and nonylphenol affect the development of forebrain GnRH neurons through an estrogen receptors-dependent pathway.
    Reproductive toxicology (Elmsford, N.Y.), 2012, Volume: 33, Issue:2

    Topics: Animals; Aromatase; Embryo, Nonmammalian; Endocrine Disruptors; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Fulvestrant; Gonadotropin-Releasing Hormone; Neurons; Phenols; Prosencephalon; Receptors, Estrogen; Zebrafish

2012
Efficacy of pharmacological estrogen receptor antagonists in blocking activation of zebrafish estrogen receptors.
    General and comparative endocrinology, 2011, Aug-01, Volume: 173, Issue:1

    Topics: Animals; Cell Line, Tumor; Estradiol; Ethinyl Estradiol; Fulvestrant; Humans; Piperidines; Pyrazoles; Pyrimidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Zebrafish

2011
The antiestrogens tamoxifen and fulvestrant abolish estrogenic impacts of 17α-ethinylestradiol on male calling behavior of Xenopus laevis.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Behavior, Animal; Endocrine Disruptors; Estradiol; Ethinyl Estradiol; Fulvestrant; Male; Tamoxifen; Vocalization, Animal; Xenopus laevis

2012
Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Cells, Cultured; Cholestasis; Dactinomycin; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Ethinyl Estradiol; Fulvestrant; Glutathione; Liver; Male; Multidrug Resistance-Associated Proteins; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Primary Cell Culture; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation

2013
The antidepressant-like effect of ethynyl estradiol is mediated by both serotonergic and noradrenergic systems in the forced swimming test.
    Neuroscience, 2013, Oct-10, Volume: 250

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Female; Fulvestrant; Idazoxan; Injections, Intraventricular; Motor Activity; Norepinephrine; Rats; Serotonin; Stereotaxic Techniques; Swimming

2013
Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche.
    Developmental cell, 2014, May-27, Volume: 29, Issue:4

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzhydryl Compounds; Core Binding Factor Alpha 2 Subunit; Ephrin-B2; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Fulvestrant; Genistein; Heat-Shock Response; Hemangioblasts; Hematopoietic Stem Cells; Morpholinos; Phenols; Proto-Oncogene Proteins; Receptors, Estradiol; Receptors, Notch; Signal Transduction; T-Cell Acute Lymphocytic Leukemia Protein 1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Zebrafish; Zebrafish Proteins

2014
Estrogenic and anti-estrogenic influences in cultured brown trout hepatocytes: Focus on the expression of some estrogen and peroxisomal related genes and linked phenotypic anchors.
    Aquatic toxicology (Amsterdam, Netherlands), 2015, Volume: 169

    Topics: Animals; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Estrogens; Ethinyl Estradiol; Fulvestrant; Gene Expression Regulation; Hepatocytes; Peroxisomes; Receptors, Estrogen; Signal Transduction; Trout; Vitellogenins; Water Pollutants, Chemical

2015