fulvestrant has been researched along with cyclin d1 in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (17.14) | 18.2507 |
| 2000's | 14 (40.00) | 29.6817 |
| 2010's | 14 (40.00) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Brady, A; deFazio, A; Musgrove, EA; Sarcevic, B; Sutherland, RL; Watts, CK | 1 |
| Foster, JS; Wimalasena, J | 1 |
| Musgrove, EA; Prall, OW; Sarcevic, B; Sutherland, RL; Watts, CK | 1 |
| Brown, M; DiRenzo, J; Dowdy, SF; Ewen, ME; Hinds, PW; Ladha, MH; Lin, N; Miller, SJ; Neuman, E; Pestell, RG; Upton, TM | 1 |
| Musgrove, EA; Prall, OW; Rogan, EM; Sutherland, RL; Watts, CK | 1 |
| Musgrove, EA; Prall, OW; Sutherland, RL; Wilcken, NR | 1 |
| Huper, G; Iglehart, JD; Lobenhofer, EK; Marks, JR | 1 |
| Carroll, JS; Musgrove, EA; Prall, OW; Sutherland, RL | 1 |
| Conrad, SE; Varma, H | 2 |
| Eghbali-Webb, M; Griffin, M; Lee, HW; Zhao, L | 1 |
| Conrad, SE; Mukherjee, S; Skildum, AJ | 1 |
| Carroll, JS; Musgrove, EA; Sutherland, RL; Swarbrick, A | 1 |
| Balkenende, A; Bindels, EM; Lallemand, F; Michalides, R; Verwoerd, D | 1 |
| Carroll, JS; Finney, GL; Hui, R; Lee, CS; Musgrove, EA; Sutherland, RL | 1 |
| Arimoto-Ishida, E; Hisamoto, K; Kurachi, H; Mabuchi, S; Mori, A; Murata, Y; Ohmichi, M; Takahashi, K; Tasaka, K; Tsutsumi, S; Yoshida, M | 1 |
| Albanese, C; Cai, D; Chernoff, J; Felekkis, KN; Iyer, A; Lerner, A; Luo, Z; Near, RI; Pestell, RG | 1 |
| Hung, H | 1 |
| Bjorling, DE; Prossnitz, ER; Teng, J; Wang, ZY | 1 |
| Brinkhuis, M; Franke, HR; Jansen, GH; Vermes, I; Wolbers, F | 1 |
| Dougherty, SM; Ivanova, MM; Klinge, CM; Mazhawidza, W | 1 |
| Kabil, A; Kortenkamp, A; Silva, E | 1 |
| Bald, L; Fayadat-Dilman, L; Grein, J; Hudak, S; Janatpour, MJ; Sathe, M; Vanderlaag, KE | 1 |
| Feng, J; He, H; Hu, Q; Huang, J; Wang, X; Yang, F; Zeng, X | 1 |
| Barrow, D; Francies, HE; Gee, JM; Goddard, L; Hutcheson, IR; Knowlden, JM; McClelland, RA; Nicholson, RI | 1 |
| Beyer, A; Cai, WY; Elledge, R; Fuqua, S; Hilsenbeck, S; Huang, J; Massarweh, S; Rimawi, M; Sexton, K; Tham, YL; Tsimelzon, A; Weiss, H | 1 |
| Giulianelli, S; Gutkind, JS; Helguero, LA; Lamb, CA; Lanari, C; Martins, R; Molinolo, AA; Soldati, R; Vanzulli, SI; Vaqué, JP; Wargon, V; Zeitlin, E | 1 |
| Giulianelli, S; Gutkind, JS; Helguero, L; Lamb, C; Lanari, C; Martins, R; Molinolo, AA; Soldati, R; Vanzulli, SI; Vaqué, JP; Wargon, V; Zeitlin, E | 1 |
| Hoffman, KL; Lerner, SP; Smith, CL | 1 |
| Aranda, E; Cañas, A; De La Haba-Rodríguez, JR; Fuentes, E; Hernández, V; López-Pedrera, C; López-Sánchez, LM; Muñoz-Castañeda, JR; Rodríguez-Ariza, A; Valverde-Estepa, A | 1 |
| Avila, E; Barrera, D; Camacho, J; Díaz, L; Esparza-López, J; García-Becerra, R; García-Quiroz, J; Halhali, A; Ibarra-Sánchez, MJ; Larrea, F; Medina-Franco, H; Ordaz-Rosado, D; Santos-Martínez, N | 1 |
| Choi, KC; Go, RE; Kim, CW | 1 |
| Arteaga, CL; Balko, JM; Bardia, A; Bauer, JA; Behdad, A; Cristofanilli, M; Croessmann, S; Cruz, MR; Dugger, TC; Ericsson, PG; Formisano, L; Guerrero-Zotano, AL; Guo, Y; Hanker, AB; He, W; Jansen, VM; Lanman, RB; Lee, KM; Lu, Y; Mayer, IA; Miller, M; Nagy, RJ; Nixon, MJ; O'Shaughnessy, J; Sanders, ME; Schwarz, LJ; Servetto, A; Shyr, Y; Solovieff, N; Su, F; Sudhan, DR | 1 |
| Yardley, DA | 1 |
| Li, Z; Liu, Z; Shao, Z; Song, C; Wang, X; Xiao, Z; Yang, X; Zhang, K | 1 |
2 trial(s) available for fulvestrant and cyclin d1
| Article | Year |
|---|---|
A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Cell Cycle; Cyclin D1; Estradiol; Female; Fulvestrant; Gefitinib; Humans; Ki-67 Antigen; Male; Mitogen-Activated Protein Kinases; Neoadjuvant Therapy; Nitriles; Oncogene Protein v-akt; Proto-Oncogene Proteins; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2011 |
MONALEESA clinical program: a review of ribociclib use in different clinical settings.
Topics: Adolescent; Adult; Aminopyridines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Estrogens; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Postmenopause; Progression-Free Survival; Purines; Receptor, ErbB-2; Tamoxifen; Young Adult | 2019 |
33 other study(ies) available for fulvestrant and cyclin d1
| Article | Year |
|---|---|
Antiestrogen inhibition of cell cycle progression in breast cancer cells in associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Estradiol; Estrogen Antagonists; Fulvestrant; Gene Expression; Humans; Oncogene Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; Tumor Cells, Cultured | 1995 |
Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells.
Topics: Breast Neoplasms; Cyclin B; Cyclin B1; Cyclin D1; Cyclin-Dependent Kinases; Cyclins; DNA; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; G1 Phase; Humans; Oncogene Proteins; Phosphorylation; Retinoblastoma Protein; S Phase; Tumor Cells, Cultured | 1996 |
Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Line; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; G1 Phase; Humans; Kinetics; Oncogene Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; S Phase; Time Factors; Tumor Cells, Cultured | 1997 |
Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.
Topics: Biomarkers, Tumor; Cell Differentiation; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Oncogene Proteins; Pregnancy; Proto-Oncogene Proteins; Receptors, Estrogen; Tamoxifen; Transcription, Genetic | 1997 |
c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry.
Topics: CDC2-CDC28 Kinases; Cell Cycle; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; G1 Phase; Humans; Molecular Mimicry; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Purines; Recombinant Fusion Proteins; Retinoblastoma-Like Protein p130; Roscovitine; S Phase; Tumor Cells, Cultured | 1998 |
Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Polyunsaturated Alkamides; Proto-Oncogene Proteins; S Phase; Tamoxifen; Tumor Cells, Cultured; Zinc Sulfate | 1997 |
Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis.
Topics: Adenocarcinoma; Androstadienes; Breast Neoplasms; Butadienes; Chromones; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Depression, Chemical; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Flavonoids; Fulvestrant; Humans; Isoquinolines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitosis; Morpholines; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Retinoblastoma Protein; Sulfonamides; Wortmannin | 2000 |
A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA-Binding Proteins; E2F4 Transcription Factor; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Kinetics; Models, Biological; Oligodeoxyribonucleotides, Antisense; Phosphoproteins; Protein Serine-Threonine Kinases; Proteins; Resting Phase, Cell Cycle; Retinoblastoma-Like Protein p130; Transcription Factors; Tumor Cells, Cultured | 2000 |
Reversal of an antiestrogen-mediated cell cycle arrest of MCF-7 cells by viral tumor antigens requires the retinoblastoma protein-binding domain.
Topics: Adenocarcinoma; Antigens, Polyomavirus Transforming; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cyclin D1; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Fulvestrant; G1 Phase; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Protein Structure, Tertiary; Recombinant Fusion Proteins; Retinoblastoma Protein; Tamoxifen; Transfection; Tumor Cells, Cultured | 2000 |
Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen.
Topics: Age Factors; Animals; Blotting, Western; Cell Division; Cell Nucleus; Cells, Cultured; Cyclin B; Cyclin B1; Cyclin D1; Cytoplasm; Cytosol; DNA; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Female; Fibroblasts; Fulvestrant; Genistein; Hypoxia; Male; Myocardium; Phosphorylation; Precipitin Tests; Proliferating Cell Nuclear Antigen; Protein Binding; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Receptors, Estrogen; Response Elements; Sex Factors; Tyrosine | 2000 |
The cyclin-dependent kinase inhibitor p21WAF1/Cip1 is an antiestrogen-regulated inhibitor of Cdk4 in human breast cancer cells.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relationship, Drug; Estradiol; Fulvestrant; Humans; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Estradiol; Estrogen Receptor Modulators; Fulvestrant; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Oligonucleotides, Antisense; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; RNA, Messenger; Tumor Suppressor Proteins; Up-Regulation | 2002 |
Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cyclin D1; Drug Resistance, Neoplasm; Enzyme Activation; Estradiol; Estrogen Receptor Modulators; Fulvestrant; Humans; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2002 |
Involvement of G1/S cyclins in estrogen-independent proliferation of estrogen receptor-positive breast cancer cells.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Cycle Proteins; Cyclin A; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA-Binding Proteins; E2F Transcription Factors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Fulvestrant; G1 Phase; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Proto-Oncogene Proteins; Receptors, Estrogen; Recombinant Fusion Proteins; S Phase; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 2002 |
Constitutive overexpression of cyclin D1 but not cyclin E confers acute resistance to antiestrogens in T-47D breast cancer cells.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Down-Regulation; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Fulvestrant; Humans; Phosphorylation; Protein Serine-Threonine Kinases; Retinoblastoma Protein; S Phase; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Both estrogen and raloxifene cause G1 arrest of vascular smooth muscle cells.
Topics: Animals; Aorta; Blotting, Western; Cell Division; Cell Line; Cells, Cultured; Cyclin D1; Depression, Chemical; Estradiol; Estrogen Receptor alpha; Flow Cytometry; Fulvestrant; G1 Phase; Humans; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Selective Estrogen Receptor Modulators; Transfection | 2003 |
AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Breast Neoplasms; Carrier Proteins; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cyclin D1; Enzyme Activation; Estradiol; Estrogen Receptor Modulators; Fulvestrant; Guanine Nucleotide Exchange Factors; Humans; Mice; Molecular Sequence Data; Neoplasms, Hormone-Dependent; NIH 3T3 Cells; p21-Activated Kinases; Promoter Regions, Genetic; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proteins; Rabbits; rac1 GTP-Binding Protein; Transfection | 2003 |
Inhibition of estrogen receptor alpha expression and function in MCF-7 cells by kaempferol.
Topics: Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cyclin D1; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Immunohistochemistry; Insulin Receptor Substrate Proteins; Kaempferols; Phosphoproteins; Receptors, Estrogen; Receptors, Progesterone; Time Factors; Transfection | 2004 |
The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferation.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cyclin D1; Estradiol; Fulvestrant; HeLa Cells; Humans; Protein Binding; Receptors, Estrogen; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction; Transcription Factor AP-1; Transfection; Urothelium | 2008 |
Effects of fulvestrant alone or combined with different steroids in human breast cancer cells in vitro.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Dydrogesterone; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Estrogens; Female; Fulvestrant; Hormone Replacement Therapy; Humans; In Vitro Techniques; Norpregnenes; Progestins; Receptors, Estrogen; RNA, Messenger | 2008 |
Sex differences in estrogen receptor subcellular location and activity in lung adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Nucleus; Cyclin D1; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fluorescence; Fulvestrant; Genome, Human; Humans; Lung Neoplasms; Male; Microscopy, Confocal; Mitogen-Activated Protein Kinases; Mutant Proteins; Phosphoserine; Protein Transport; Sex Characteristics; Signal Transduction; Subcellular Fractions; Tamoxifen | 2010 |
Cross-talk between non-genomic and genomic signalling pathways--distinct effect profiles of environmental estrogens.
Topics: BRCA1 Protein; Cell Line, Tumor; Cell Proliferation; Cyclin D1; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Enzyme Activation; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Profiling; Hexachlorocyclohexane; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptors, Estrogen; Signal Transduction; src-Family Kinases; Trefoil Factor-1; Tumor Suppressor Proteins | 2010 |
Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivin.
Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colony-Forming Units Assay; Cyclin D1; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Flow Cytometry; Fulvestrant; Humans; Immunization; Inhibitor of Apoptosis Proteins; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Mucoproteins; Oncogene Proteins; Proteins; Rats; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Survivin; Tamoxifen | 2010 |
Complete estrogen receptor blocker ICI182,780 promotes the proliferation of vascular smooth muscle cells.
Topics: Animals; Breast Neoplasms; Cell Division; Cell Line; Cyclin D1; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Receptors, Estrogen; S Phase | 2011 |
Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Drug Resistance, Neoplasm; ErbB Receptors; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Intracellular Signaling Peptides and Proteins; Neuregulin-1; Receptor, ErbB-3; Receptor, ErbB-4; Receptors, Estrogen; Signal Transduction | 2011 |
Estrogen receptor alpha mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters.
Topics: Animals; Breast Neoplasms; Cell Growth Processes; Cell Nucleus; Cyclin D1; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Genes, myc; Genes, Reporter; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Neoplasms, Hormone-Dependent; Promoter Regions, Genetic; Receptors, Progesterone | 2012 |
[The role of estrogen receptor alpha in breast cancer cell proliferation mediated by progestins].
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Cell Proliferation; Chromatin Immunoprecipitation; Cyclin D1; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Genes, myc; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Murinae; Progestins; Receptors, Progesterone; Transcription, Genetic | 2012 |
Raloxifene inhibits growth of RT4 urothelial carcinoma cells via estrogen receptor-dependent induction of apoptosis and inhibition of proliferation.
Topics: Apoptosis; Carcinoma, Transitional Cell; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Humans; Immediate-Early Proteins; MCF-7 Cells; Poly(ADP-ribose) Polymerases; Raloxifene Hydrochloride; S-Phase Kinase-Associated Proteins; Tamoxifen; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2013 |
Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors.
Topics: Antineoplastic Agents, Hormonal; Antirheumatic Agents; Auranofin; Benzothiazoles; Breast Neoplasms; CD24 Antigen; Cell Proliferation; Cell Survival; Cyclin D1; Cysteine; Estradiol; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Female; Fulvestrant; Homeostasis; Humans; Hyaluronan Receptors; MCF-7 Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Messenger; RNA, Small Interfering; S-Nitrosothiols; Spheroids, Cellular; Thioredoxin-Disulfide Reductase; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2012 |
Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: a potential new therapeutic approach.
Topics: Breast Neoplasms; Calcitriol; Cell Line, Tumor; Cyclin D1; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Receptors, Calcitriol | 2014 |
Effect of fenhexamid and cyprodinil on the expression of cell cycle- and metastasis-related genes via an estrogen receptor-dependent pathway in cellular and xenografted ovarian cancer models.
Topics: Amides; Animals; Cathepsin D; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin E; Estradiol; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oncogene Proteins; Ovarian Neoplasms; Pyrimidines; Receptors, Estrogen | 2015 |
Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer.
Topics: Aminopyridines; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Circulating Tumor DNA; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Drug Resistance, Neoplasm; Female; Fulvestrant; High-Throughput Nucleotide Sequencing; Humans; MCF-7 Cells; Mice; Mutation; Naphthalenes; Piperazines; Progression-Free Survival; Proportional Hazards Models; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyridines; Quinolines; Quinoxalines; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptors, Estrogen; Signal Transduction; Xenograft Model Antitumor Assays | 2019 |
Estrogen receptor α/prolactin receptor bilateral crosstalk promotes bromocriptine resistance in prolactinomas.
Topics: Adolescent; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromocriptine; Cell Line, Tumor; Cyclin D1; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Hypophysectomy; Male; MAP Kinase Signaling System; Middle Aged; Neoplasm Recurrence, Local; Pituitary Gland; Pituitary Neoplasms; Prolactin; Prolactinoma; Rats; Receptors, Prolactin; Young Adult | 2020 |