fulvestrant has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (68.75) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Huper, G; Iglehart, JD; Lobenhofer, EK; Marks, JR | 1 |
| Akaike, A; Honda, K; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Bucci, M; Cicala, C; Cirino, G; Pinto, A; Roviezzo, F | 1 |
| Czubayko, F; Franke, TF; List, HJ; Martin, MB; Morgan, E; Reiter, R; Stoica, A; Stoica, GE; Wellstein, A | 1 |
| Aronovitz, MJ; Baur, J; Celestin, F; Chen, X; Force, T; Grohe, C; Haq, S; Karas, RH; Mendelsohn, ME; Michael, A; Nuedling, S; Patten, RD; Pourati, I | 1 |
| Castro, AF; Felekkis, KN; Lerner, A; Narsimhan, RP; Near, R; Quilliam, LA; Zheng, Y | 1 |
| Han, D; Lü, Q; Wang, R; Xu, J; Zhang, GY; Zhang, QG | 1 |
| Chen, J; Fang, Y; Huang, L; Yin, Y; Zhao, J; Zhao, X | 1 |
| Arshad, F; Braun, AP; Braun, JE; Sheng, JZ | 1 |
| Han, HJ; Lee, MY; Park, JH | 1 |
| Aleskandarany, M; Ball, G; Douglas Macmillan, R; Ellis, IO; Gee, JM; Green, AR; Habashy, HO; Nicholson, RI; Paish, EC; Powe, DG; Rakha, EA; Staka, CM | 1 |
| Chan, YC; Chen, ZY; Huang, Y; Lau, CW; Leung, FP; Tian, XY; Tsang, SY; Wong, WT; Yao, X; Yung, LM | 1 |
| Ding, L; Kang, L; Wang, ZY; Zhang, X | 1 |
| Chen, CS; Hsu, YY; Lo, YC; Tseng, YT | 1 |
| Förstermann, U; Hohmann, N; Li, H; Steinkamp-Fenske, K; Xia, N | 1 |
16 other study(ies) available for fulvestrant and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis.
Topics: Adenocarcinoma; Androstadienes; Breast Neoplasms; Butadienes; Chromones; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Depression, Chemical; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Flavonoids; Fulvestrant; Humans; Isoquinolines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitosis; Morpholines; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Retinoblastoma Protein; Sulfonamides; Wortmannin | 2000 |
Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Excitatory Amino Acid Antagonists; Flavonoids; Fulvestrant; Glutamic Acid; Morpholines; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley | 2000 |
17-beta-oestradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism.
Topics: Animals; Aorta, Thoracic; Chromones; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Estradiol; Estrogen Antagonists; Fulvestrant; HSP90 Heat-Shock Proteins; Male; Morpholines; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Estrogen; Vasodilation | 2002 |
Estradiol rapidly activates Akt via the ErbB2 signaling pathway.
Topics: Androstadienes; Breast Neoplasms; Chromones; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Genistein; Humans; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptors, Estrogen; Serine; Signal Transduction; Sirolimus; Tumor Cells, Cultured; Tyrphostins; Wortmannin | 2003 |
17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling.
Topics: Amino Acid Chloromethyl Ketones; Androstadienes; Animals; Apoptosis; Cells, Cultured; Chromones; Enzyme Activation; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Myocardial Infarction; Myocytes, Cardiac; Ovariectomy; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Fusion Proteins; Signal Transduction; Wortmannin | 2004 |
AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.
Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromones; Crk-Associated Substrate Protein; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogens; Focal Adhesions; Fulvestrant; Genes, Dominant; Genetic Vectors; GTP Phosphohydrolases; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; rac GTP-Binding Proteins; Receptors, Estrogen; Retinoblastoma-Like Protein p130; Serine; Signal Transduction; src Homology Domains; Transfection | 2005 |
Inhibition of MLK3-MKK4/7-JNK1/2 pathway by Akt1 in exogenous estrogen-induced neuroprotection against transient global cerebral ischemia by a non-genomic mechanism in male rats.
Topics: Animals; Blotting, Western; Chromones; Disease Models, Animal; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Hippocampus; Immunohistochemistry; Immunoprecipitation; Ischemic Attack, Transient; Male; MAP Kinase Kinase 7; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinase Kinase 11; Morpholines; Neuroprotective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction | 2006 |
Estrogen induces endothelial progenitor cells proliferation and migration by estrogen receptors and PI3K-dependent pathways.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Chromones; Endothelial Cells; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Humans; Mice; Mice, Inbred C57BL; Morpholines; Phenotype; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Signal Transduction; Stem Cells | 2008 |
Estrogen and the Ca2+-mobilizing agonist ATP evoke acute NO synthesis via distinct pathways in an individual human vascular endothelium-derived cell.
Topics: Adenosine Triphosphate; Apamin; Calcium Signaling; Cell Line; Charybdotoxin; Chelating Agents; Chromones; Cytophotometry; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Humans; Membrane Potentials; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Protein Kinase Inhibitors; Time Factors; Up-Regulation | 2008 |
A potential role for caveolin-1 in estradiol-17beta-induced proliferation of mouse embryonic stem cells: involvement of Src, PI3K/Akt, and MAPKs pathways.
Topics: Animals; Caveolin 1; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Chromones; Embryonic Stem Cells; Estradiol; Estrogen Antagonists; Fulvestrant; MAP Kinase Signaling System; Mice; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; RNA, Small Interfering; src-Family Kinases | 2009 |
Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen.
Topics: Adult; Antigens, CD; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Chromones; Drug Resistance, Neoplasm; Estradiol; Female; Flavonoids; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Predictive Value of Tests; Proportional Hazards Models; Protein Kinase Inhibitors; Receptors, Estrogen; Receptors, Transferrin; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; RNA, Messenger; Tamoxifen; Time Factors; Tissue Array Analysis; Transferrin; Treatment Outcome | 2010 |
Therapeutically relevant concentrations of raloxifene dilate pressurized rat resistance arteries via calcium-dependent endothelial nitric oxide synthase activation.
Topics: Androstadienes; Animals; Apamin; Blood Pressure; Calcium Signaling; Charybdotoxin; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; In Vitro Techniques; Male; Mesenteric Arteries; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Ovariectomy; Phosphorylation; Potassium Channel Blockers; Protein Kinase Inhibitors; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Sex Factors; Time Factors; Vascular Resistance; Vasodilation; Vasodilator Agents; Wortmannin | 2010 |
Estrogen receptor-alpha 36 mediates mitogenic antiestrogen signaling in ER-negative breast cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromones; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Hydroxytestosterones; Immunoblotting; Immunoprecipitation; Morpholines; Phosphorylation; Signal Transduction | 2012 |
Nrf2-Keap1 antioxidant defense and cell survival signaling are upregulated by 17β-estradiol in homocysteine-treated dopaminergic SH-SY5Y cells.
Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Chromones; Cytochromes c; Dopaminergic Neurons; Estradiol; Estrogen Antagonists; Fulvestrant; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Homocysteine; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Morpholines; NF-E2-Related Factor 2; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Up-Regulation | 2013 |
Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation.
Topics: Androstadienes; Animals; Betulinic Acid; Cell Line; Chromones; Estradiol; Fibroblasts; Fulvestrant; Gene Expression Regulation; Humans; Lung; Morpholines; Nitric Oxide Synthase Type III; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Receptors, Estrogen; Signal Transduction; Triterpenes; Wortmannin | 2016 |