fullerene-c70 and malonic-acid

fullerene-c70 has been researched along with malonic-acid* in 2 studies

Other Studies

2 other study(ies) available for fullerene-c70 and malonic-acid

Article	Year
Atomic force microscopy study of the effects of water-soluble fullerenes on the elasticity of living plant cells. Chemistry, an Asian journal, 2013, Volume: 8, Issue:10 In this work, atomic force microscopy (AFM) was employed to characterize the elastic properties of a living suspension of Nicotiana tabacum L. cv. Bright Yellow (BY-2) cells and to investigate the changes in plant-cell elasticity that were induced by water-soluble C70 fullerene derivatives. The results revealed different effects of the three fullerene derivatives that had different numbers of carboxylic groups on the cell elasticity. BY-2 cells that were repressed by dimalonic-acid-modified C70 fullerenes (DiF70) and trimalonic-acid-modified C70 fullerenes (TriF70) showed a clear decrease in their Young's modulus. However, the Young's modulus of cells that were treated with tetramalonic-acid-modified C70 fullerenes (TetraF70) increased. Disruption of the actin cytoskeleton arrangement was observed following treatment with DiF70 and TriF70, but not with TetraF70. Moreover, the fullerene-induced cell-elasticity change was consistent with the change in cell-proliferation rate. This work provides a new approach and valuable information for the study of the biological effect of nanomaterials on plant cells. Topics: Elastic Modulus; Fullerenes; Malonates; Microscopy, Atomic Force; Nicotiana; Plant Cells; Water	2013
Structural effect and mechanism of C70-carboxyfullerenes as efficient sensitizers against cancer cells. Small (Weinheim an der Bergstrasse, Germany), 2012, Jul-09, Volume: 8, Issue:13 Carboxyfullerenes with different adduct numbers and cage sizes are tested as photosensitizers for photodynamic therapy (PDT). The photodynamic efficiency of these carboxyfullerenes depends mainly on the cage size, C(60) versus C(70) , and to a lesser extent on the adduct numbers. In particular, malonic acid modified C(70) fullerenes are more efficient than their C(60) counterparts as photosensitizers, and the mechanism of cell death induced by C(70) -carboxyfullerene under light irradiation is investigated in detail. The results indicate that cell death occurs via necrosis accompanied by membrane blebbing, which is a unique phenomenon for photosensitizer-induced cell death. Since C(70) -carboxyfullerene displays an efficient PDT property and negligible dark cytotoxicity, it is promising for use in PDT applications, especially in vascular capillary diseases usually occurring under the surface. Topics: Cell Survival; Fullerenes; HeLa Cells; Humans; Light; Malonates; Microscopy, Electron, Transmission; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species	2012

Article

Year

Atomic force microscopy study of the effects of water-soluble fullerenes on the elasticity of living plant cells.

Chemistry, an Asian journal, 2013, Volume: 8, Issue:10

In this work, atomic force microscopy (AFM) was employed to characterize the elastic properties of a living suspension of Nicotiana tabacum L. cv. Bright Yellow (BY-2) cells and to investigate the changes in plant-cell elasticity that were induced by water-soluble C70 fullerene derivatives. The results revealed different effects of the three fullerene derivatives that had different numbers of carboxylic groups on the cell elasticity. BY-2 cells that were repressed by dimalonic-acid-modified C70 fullerenes (DiF70) and trimalonic-acid-modified C70 fullerenes (TriF70) showed a clear decrease in their Young's modulus. However, the Young's modulus of cells that were treated with tetramalonic-acid-modified C70 fullerenes (TetraF70) increased. Disruption of the actin cytoskeleton arrangement was observed following treatment with DiF70 and TriF70, but not with TetraF70. Moreover, the fullerene-induced cell-elasticity change was consistent with the change in cell-proliferation rate. This work provides a new approach and valuable information for the study of the biological effect of nanomaterials on plant cells.

Topics: Elastic Modulus; Fullerenes; Malonates; Microscopy, Atomic Force; Nicotiana; Plant Cells; Water

2013

Structural effect and mechanism of C70-carboxyfullerenes as efficient sensitizers against cancer cells.

Small (Weinheim an der Bergstrasse, Germany), 2012, Jul-09, Volume: 8, Issue:13

Carboxyfullerenes with different adduct numbers and cage sizes are tested as photosensitizers for photodynamic therapy (PDT). The photodynamic efficiency of these carboxyfullerenes depends mainly on the cage size, C(60) versus C(70) , and to a lesser extent on the adduct numbers. In particular, malonic acid modified C(70) fullerenes are more efficient than their C(60) counterparts as photosensitizers, and the mechanism of cell death induced by C(70) -carboxyfullerene under light irradiation is investigated in detail. The results indicate that cell death occurs via necrosis accompanied by membrane blebbing, which is a unique phenomenon for photosensitizer-induced cell death. Since C(70) -carboxyfullerene displays an efficient PDT property and negligible dark cytotoxicity, it is promising for use in PDT applications, especially in vascular capillary diseases usually occurring under the surface.

Topics: Cell Survival; Fullerenes; HeLa Cells; Humans; Light; Malonates; Microscopy, Electron, Transmission; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species

2012