fuculose-1-phosphate and lactaldehyde

fuculose-1-phosphate has been researched along with lactaldehyde* in 1 studies

Other Studies

1 other study(ies) available for fuculose-1-phosphate and lactaldehyde

Article	Year
Identification of lactaldehyde dehydrogenase in Methanocaldococcus jannaschii and its involvement in production of lactate for F420 biosynthesis. Journal of bacteriology, 2006, Volume: 188, Issue:8 One of the early steps in the biosynthesis of coenzyme F(420) in Methanocaldococcus jannaschii requires generation of 2-phospho-L-lactate, which is formed by the phosphorylation of L-lactate. Preliminary studies had shown that L-lactate in M. jannaschii is not derived from pyruvate, and thus an alternate pathway(s) for its formation was examined. Here we report that L-lactate is formed by the NAD(+)-dependent oxidation of l-lactaldehyde by the MJ1411 gene product. The lactaldehyde, in turn, was found to be generated either by the NAD(P)H reduction of methylglyoxal or by the aldol cleavage of fuculose-1-phosphate by fuculose-1-phosphate aldolase, the MJ1418 gene product. Topics: Aldehyde Oxidoreductases; Aldehydes; Amino Acid Sequence; Archaeal Proteins; Cloning, Molecular; Escherichia coli; Fructose-Bisphosphate Aldolase; Hexosephosphates; Lactic Acid; Methanococcales; Molecular Sequence Data; Pyruvaldehyde; Recombinant Proteins; Riboflavin; Sequence Homology, Amino Acid	2006

Article

Year

Identification of lactaldehyde dehydrogenase in Methanocaldococcus jannaschii and its involvement in production of lactate for F420 biosynthesis.

Journal of bacteriology, 2006, Volume: 188, Issue:8

One of the early steps in the biosynthesis of coenzyme F(420) in Methanocaldococcus jannaschii requires generation of 2-phospho-L-lactate, which is formed by the phosphorylation of L-lactate. Preliminary studies had shown that L-lactate in M. jannaschii is not derived from pyruvate, and thus an alternate pathway(s) for its formation was examined. Here we report that L-lactate is formed by the NAD(+)-dependent oxidation of l-lactaldehyde by the MJ1411 gene product. The lactaldehyde, in turn, was found to be generated either by the NAD(P)H reduction of methylglyoxal or by the aldol cleavage of fuculose-1-phosphate by fuculose-1-phosphate aldolase, the MJ1418 gene product.

Topics: Aldehyde Oxidoreductases; Aldehydes; Amino Acid Sequence; Archaeal Proteins; Cloning, Molecular; Escherichia coli; Fructose-Bisphosphate Aldolase; Hexosephosphates; Lactic Acid; Methanococcales; Molecular Sequence Data; Pyruvaldehyde; Recombinant Proteins; Riboflavin; Sequence Homology, Amino Acid

2006