Compounds > frenolicin b

Page last updated: 2024-09-04

frenolicin b and naphthoquinones

frenolicin b has been researched along with naphthoquinones in 16 studies

Compound Research Comparison

Studies (frenolicin b)	Trials (frenolicin b)	Recent Studies (post-2010) (frenolicin b)	Studies (naphthoquinones)	Trials (naphthoquinones)	Recent Studies (post-2010) (naphthoquinones)
18	0	9	7,110	149	2,923

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (12.50)	18.7374
1990's	2 (12.50)	18.2507
2000's	5 (31.25)	29.6817
2010's	7 (43.75)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Iwai, Y; Kitajima, N; Omura, S; Shimizu, H; Tsuzuki, K	1
Iwai, Y; Kishi, M; Omura, S; Shimizu, H; Tsuzuki, K; Watanabe, S	1
Bibb, MJ; Hopwood, DA; Omura, S; Sherman, DH	1
Armer, RE; Dutton, CJ; Fenner, BR; Greenwood, SD; Hall, KT; Rudge, AJ	1
Bogden, JD; Davidovich, A; Han, S; Kemp, FW; Kossor, DC; Milner, N; Rajaskarian, D; Serota, D; Slauter, RW	1
Khosla, C; Li, Q; Liu, CW; Puglisi, JD	1
Khosla, C; Koppisch, AT	1
Ellestad, GA	1
Ding, WD; Eid, C; Hanna, C; Honores, E; Insaf, SS; Johnson, B; Krishnamurthy, G; Laakso, L; Levin, JI; Li, Z; Mansour, TS; McDonald, LA; Powell, D; Salaski, EJ; Shim, J; Tabei, K; Toral-Barza, L; Yamashita, A; Yu, K; Zhang, WG	1
Fitzgerald, JT; Khosla, C; Ridley, CP	1
Ekland, EH; Fidock, D; Fitzgerald, JT; Henrich, PP; Khosla, C; Krause, M; Mattheis, C; O'Brien, C; Sá, JM	1
Chavan, VP; Fernandes, RA; Manchoju, A; Mulay, SV	1
Copley, GC; Elshahawi, SI; Hower, JC; Kharel, MK; Morris, AJ; Ponomareva, LV; Shaaban, KA; Sunkara, M; Thorson, JS; Wang, X; Zhang, Y	1
Morris, AJ; Ponomereva, LV; She, QB; Sunkara, M; Thorson, JS; Wang, X; Ye, Q; Zhang, Y	1
Copley, GC; Elshahawi, SI; Fang, L; Hower, JC; Kharel, MK; Ponomareva, LV; Shaaban, KA; Thorson, JS; Wang, X; Zhan, CG; Zhang, Y	1
Anderson, BD; Cao, Y; Chaiswing, L; Chen, J; Guo, Y; Horn, J; Leggas, M; Ponomareva, LV; Shaaban, KA; She, QB; St Clair, DK; Thorson, JS; Wang, X; Wei, Q; Ye, Q; Zhang, Y; Zhu, H	1

Other Studies

16 other study(ies) available for frenolicin b and naphthoquinones

Article	Year
Nanaomycins production by a frenolicin B producing strain. The Journal of antibiotics, 1986, Volume: 39, Issue:9 Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Naphthoquinones; Streptomyces	1986
Anticoccidial activity of frenolicin B and its derivatives. The Journal of antibiotics, 1985, Volume: 38, Issue:10 Topics: Animals; Anti-Bacterial Agents; Chickens; Coccidiostats; Naphthoquinones; Structure-Activity Relationship	1985
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin. Gene, 1994, May-03, Volume: 142, Issue:1 Topics: Acyltransferases; Alcohol Oxidoreductases; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA, Bacterial; Genes, Bacterial; Molecular Sequence Data; Multigene Family; Naphthoquinones; Open Reading Frames; Polyketide Synthases; Restriction Mapping; Streptomyces	1994
Carbocyclic frenolicin analogues: novel anticoccidial agents. Bioorganic & medicinal chemistry letters, 1998, Jan-20, Volume: 8, Issue:2 Topics: Animals; Antiprotozoal Agents; Coccidiosis; Eimeria; Naphthoquinones; Stereoisomerism; Structure-Activity Relationship	1998
Administration of the oral antibiotic frenolicin-B selectively alters copper nutriture in male rats. The Journal of nutrition, 2001, Volume: 131, Issue:12 Topics: Animals; Anti-Bacterial Agents; Brain Chemistry; Copper; Diet; Epithelium; Esophagus; Femur; Hyperplasia; Iron; Iron Deficiencies; Kidney; Magnesium; Magnesium Deficiency; Naphthoquinones; Organ Size; Rats; Rats, Sprague-Dawley; Salivary Glands; Stomach; Tongue; Zinc	2001
Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein. Biochemistry, 2003, Apr-29, Volume: 42, Issue:16 Topics: Acyl Carrier Protein; Amino Acid Sequence; Models, Chemical; Models, Molecular; Molecular Sequence Data; Naphthoquinones; Nuclear Magnetic Resonance, Biomolecular; Pantetheine; Protein Conformation; Sequence Alignment; Streptomyces	2003
Structure-based mutagenesis of the malonyl-CoA:acyl carrier protein transacylase from Streptomyces coelicolor. Biochemistry, 2003, Sep-23, Volume: 42, Issue:37 Topics: Acyl-Carrier Protein S-Malonyltransferase; Acyltransferases; Amino Acid Sequence; Circular Dichroism; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis; Mutation; Naphthoquinones; Plasmids; Protein Binding; Streptomyces; Temperature; Time Factors	2003
From natural products to bioorganic chemistry. What's next? Journal of medicinal chemistry, 2006, Nov-16, Volume: 49, Issue:23 Topics: Aminoglycosides; Anti-Bacterial Agents; Anticholesteremic Agents; Antiviral Agents; Awards and Prizes; Biological Products; Chemistry, Pharmaceutical; Cytomegalovirus; Dacarbazine; Endopeptidases; Enediynes; Glycopeptides; Naphthoquinones; Serine Proteinase Inhibitors; Societies, Scientific; Spermidine; Tetracyclines; Viral Proteins	2006
Pyranonaphthoquinone lactones: a new class of AKT selective kinase inhibitors alkylate a regulatory loop cysteine. Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8 Topics: Alkylation; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cell Proliferation; Cysteine; Humans; Lactones; Naphthoquinones; Oncogene Protein v-akt; Pyrans; Stereoisomerism; Structure-Activity Relationship	2009
Engineered biosynthesis of the antiparasitic agent frenolicin B and rationally designed analogs in a heterologous host. The Journal of antibiotics, 2011, Volume: 64, Issue:12 Topics: Animals; Antiparasitic Agents; Cell Line; Cloning, Molecular; Genetic Engineering; Humans; Magnetic Resonance Spectroscopy; Naphthoquinones; Streptomyces coelicolor; Toxoplasma	2011
In vitro and in vivo activity of frenolicin B against Plasmodium falciparum and P berghei. The Journal of antibiotics, 2011, Volume: 64, Issue:12 Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mice; Naphthoquinones; Plasmodium berghei; Plasmodium falciparum	2011
A chiron approach to the total synthesis of (-)-juglomycin A, (+)-kalafungin, (+)-frenolicin B, and (+)-deoxyfrenolicin. The Journal of organic chemistry, 2012, Nov-16, Volume: 77, Issue:22 Topics: Alkynes; Molecular Structure; Naphthoquinones; Stereoisomerism	2012
Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. Journal of natural products, 2013, Aug-23, Volume: 76, Issue:8 Topics: Actinobacteria; Appalachian Region; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Naphthoquinones; Pyrones; Spectrometry, Mass, Electrospray Ionization; Streptomyces; Structure-Activity Relationship	2013
A diastereoselective oxa-Pictet-Spengler-based strategy for (+)-frenolicin B and epi-(+)-frenolicin B synthesis. Organic letters, 2013, Nov-01, Volume: 15, Issue:21 Topics: Chromans; Cyclization; Molecular Structure; Naphthoquinones; Stereoisomerism	2013
Ruthmycin, a new tetracyclic polyketide from Streptomyces sp. RM-4-15. Organic letters, 2014, Jan-17, Volume: 16, Issue:2 Topics: Antifungal Agents; Kentucky; Microbial Sensitivity Tests; Molecular Structure; Naphthoquinones; Nuclear Magnetic Resonance, Biomolecular; Polyketides; Streptomyces	2014
Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects. Cell chemical biology, 2019, 03-21, Volume: 26, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Glutaredoxins; Humans; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Nude; Naphthoquinones; Neoplasms; Peroxiredoxins; Phosphorylation; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Signal Transduction; Transplantation, Heterologous	2019