fraxinellone has been researched along with benzofurans in 40 studies
| Studies (fraxinellone) | Trials (fraxinellone) | Recent Studies (post-2010) (fraxinellone) | Studies (benzofurans) | Trials (benzofurans) | Recent Studies (post-2010) (benzofurans) |
|---|---|---|---|---|---|
| 46 | 0 | 34 | 13,293 | 451 | 4,970 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 9 (22.50) | 29.6817 |
| 2010's | 19 (47.50) | 24.3611 |
| 2020's | 11 (27.50) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM | 1 |
| Goh, SH; Ho, SH; Liu, ZL; Wu, J; Xu, YJ | 1 |
| Morken, JP; Trudeau, S | 1 |
| Jia, TL; Yang, RL; Zhang, RQ | 1 |
| Yang, DS; Yuan, CL | 1 |
| Ran, QQ; Ruan, LP; Yu, BY; Zhu, DN | 1 |
| Chen, T; Gong, FY; Hua, ZC; Qin, Y; Sun, Y; Wu, XF; Xu, Q | 1 |
| Choi, JH; Jung, HJ; Kim, JH; Lee, KT; Park, HJ; Park, SJ; Park, YM; Shin, JS | 1 |
| Cho, Y; Chung, MH; Lee, CS; Maeng, JW; Sung, SH; Won, C; Ye, SK; Yi, EH; Yoo, H | 1 |
| Chen, L; Guan, Y; Ou, S; Wang, S; Yang, M; Zhu, W | 1 |
| Chen, L; Guan, Y; Ou, S; Wang, S; Wu, D; Zhu, W | 1 |
| Guo, Y; Hu, Y; Wang, Y; Xu, H; Yan, Y; Yu, X; Zhi, XY | 1 |
| Guo, Y; Xu, H; Yan, YY; Yang, C; Yu, X; Zhi, XY | 1 |
| Liu, H; Lü, M; Wu, W | 1 |
| Gao, E; Qu, W; Sun, J; Wang, P; Yu, Z; Zhao, Y | 1 |
| Guo, Y; Qu, H; Xu, H; Yang, C; Yu, X; Zhi, X | 1 |
| Liu, H; Lv, M; Wu, W | 1 |
| Chen, G; Feng, LL; Guo, WJ; Ouyang, ZJ; Shen, Y; Sun, Y; Wu, XD; Wu, XF; Xu, Q | 1 |
| Gao, S; Hu, M; Ma, Y; Xu, B; Yang, G; Yin, T; You, M | 1 |
| Huang, X; Li, Q; Li, S; Lv, M; Ma, J; Xu, H | 1 |
| Gu, L; Ma, Y; Shao, F; Sun, B; Sun, Y; Tan, T; Tan, Y; Wu, X; Xu, Q; Zhou, Y | 1 |
| Chen, H; Fang, T; Gong, H; Han, X; Huang, N; Qin, J; Tai, H; Wang, F; Wang, X; Xiao, H; Zhou, J | 1 |
| Baek, SY; Cho, ML; Hong, SM; Jang, SG; Jung, SM; Kwok, SK; Lee, J; Park, JS; Park, SH | 1 |
| Chen, F; Hou, L; Huang, L; Liu, Q; Liu, Y; Shen, L; Zhang, X | 1 |
| Jin, X; Li, MY; Ma, J; Mi, C; Wang, JY; Wang, Z; Xing, Y; Zhang, ZH; Zuo, HX | 1 |
| Fan, Q; Wang, C; Wang, T; Wu, J; Xu, A; Zhang, J; Zhao, B | 1 |
| Bao, C; Fan, J; Guo, Y; Liu, Z; Yang, R; Zhang, Q | 1 |
| Bae, GS; Choi, SB; Jo, IJ; Jung, HJ; Kim, DG; Kim, MJ; Park, SJ; Song, HJ | 1 |
| Chen, J; Chen, L; Chen, Y; Feng, J; Gao, X; Gu, X; Huang, Y; Jiang, G; Pei, Y; Song, Q; Wang, J; Xu, M; Zhang, Q | 1 |
| Dong, QM; Tang, JJ; Wang, MR; Yang, XJ | 1 |
| Gou, X; Lei, J; Li, Z; Wei, S; Zhou, J | 1 |
| Li, Y; Liu, Q; Wang, C; Yao, J; Zhang, J; Zhang, L; Zhang, X; Zhang, Y; Zhou, H | 1 |
| Chen, S; Lv, M; Xu, H; Zhang, S | 1 |
| Bailly, C; Vergoten, G | 1 |
| Fu, Z; Li, B; Tang, Y; Wang, X | 1 |
| Gao, Y; Kong, L; Sun, X; Tan, Y; Wang, S; Wang, T; Wu, X; Xu, Q; Xu, Y; Ye, J; Yuan, M; Zheng, B | 1 |
| Bui, D; Duan, S; Hu, M; Singh, R; Wei, B; Wong, SJ; Yang, P; Yin, T; You, M | 1 |
| Chen, G; Cui, G; Li, H; Li, X; Lu, T; Peng, S; Shen, H; Wang, J; Xu, X; Yang, S | 1 |
| Bao, J; Hu, Y; Jin, H; Li, J; Li, W; Li, X; Pang, F; Qiu, C; Tian, M; Wang, S; Yang, J | 1 |
| Chen, Z; Huang, C; Huang, Y; Huang, Z; Shi, J; Sun, S; Wang, Q; Wang, Y; Xing, S; Xue, X | 1 |
1 review(s) available for fraxinellone and benzofurans
| Article | Year |
|---|---|
Fraxinellone: From pesticidal control to cancer treatment.
Topics: Animals; Benzofurans; Insecticides; Larva; Moths | 2020 |
39 other study(ies) available for fraxinellone and benzofurans
| Article | Year |
|---|---|
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Aorta, Thoracic; Benzofurans; Benzopyrans; Calcium; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Female; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium Channels; Potassium Chloride; Pyrroles; Quinolines; Rats; Rats, Inbred Strains; Verapamil | 1992 |
Feeding deterrents from Dictamnus dasycarpus Turcz against two stored-product insects.
Topics: Alkaloids; Animals; Benzofurans; Chemical Fractionation; Eating; Food Contamination; Insecta; Larva; Plant Extracts; Plant Roots; Quinolines; Tribolium | 2002 |
Short and efficient total synthesis of fraxinellone limonoids using the stereoselective Oshima-Utimoto reaction.
Topics: Benzofurans; Crystallography, X-Ray; Limonins; Molecular Conformation; Molecular Structure; Stereoisomerism | 2005 |
Microbial transformation of fraxinellone by Aspergillus niger.
Topics: Antineoplastic Agents, Phytogenic; Aspergillus niger; Benzofurans; Cell Line, Tumor; Dictamnus; Humans; Mass Spectrometry; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal | 2005 |
[Determination of fraxinellone in root bark of Dictamnus dasycarpus by RP-HPLC].
Topics: Benzofurans; Chromatography, High Pressure Liquid; Dictamnus; Plant Roots; Plants, Medicinal; Quality Control; Reproducibility of Results | 2006 |
[Improving the solubility of fraxinellone to increase its oral bioavailability and hepatoprotective action against acute liver injury in mice].
Topics: Animals; Benzofurans; Biological Availability; Carbon Tetrachloride; Female; Hydrogen-Ion Concentration; Liver; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Solubility | 2007 |
Selective triggering of apoptosis of concanavalin A-activated T cells by fraxinellone for the treatment of T-cell-dependent hepatitis in mice.
Topics: Animals; Apoptosis; Benzofurans; Concanavalin A; Female; Hepatitis, Animal; Lymphocyte Activation; Membrane Potentials; Mice; Mice, Inbred C57BL; Mitochondrial Membranes; T-Lymphocytes | 2009 |
Fraxinellone inhibits lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by negatively regulating nuclear factor-kappa B in RAW 264.7 macrophages cells.
Topics: Animals; Benzofurans; Blotting, Western; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dictamnus; Dinoprostone; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Immunoprecipitation; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Roots; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Inhibition of double-stranded RNA-induced inducible nitric oxide synthase expression by fraxinellone and sauchinone in murine microglia.
Topics: Animals; Base Sequence; Benzofurans; Benzopyrans; Blotting, Western; Dioxoles; DNA Primers; Mice; Microglia; Nitric Oxide Synthase Type II; RNA, Double-Stranded; Toll-Like Receptor 3; Transcription, Genetic | 2009 |
[Effects of penetration enhancers on in vitro percutaneous absorption and amount retained in skin of paeonol, dictamnine, fraxinellone and glycyrrhetinic acid in Liangfu cream].
Topics: Acetophenones; Administration, Cutaneous; Animals; Benzofurans; Drug Carriers; Drugs, Chinese Herbal; Glycyrrhetinic Acid; Male; Mice; Quinolines; Skin; Skin Absorption | 2009 |
[Dermatopharmacokinetic studies of liangfu cream in mice skin].
Topics: Acetophenones; Administration, Cutaneous; Animals; Benzofurans; Drugs, Chinese Herbal; Glycyrrhetinic Acid; Male; Mice; Quinolines; Skin | 2010 |
Synthesis and insecticidal activity of some novel fraxinellone-based esters.
Topics: Animals; Benzofurans; Crystallography, X-Ray; Esters; Insecticides; Larva; Moths | 2012 |
Regioselective synthesis of fraxinellone-based hydrazone derivatives as insecticidal agents.
Topics: Animals; Benzofurans; Hydrazones; Insecticides; Models, Molecular; Moths; Stereoisomerism; Structure-Activity Relationship | 2012 |
Insecticidal and feeding deterrent effects of fraxinellone from Dictamnus dasycarpus against four major pests.
Topics: Animals; Benzofurans; Dictamnus; Dose-Response Relationship, Drug; Embryonic Development; Insecta; Insecticides; Larva; Lepidoptera | 2013 |
Simultaneous determination of limonin, dictamnine, obacunone and fraxinellone in rat plasma by a validated UHPLC-MS/MS and its application to a pharmacokinetic study after oral administration of Cortex Dictamni extract.
Topics: Administration, Oral; Animals; Benzofurans; Benzoxepins; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Limonins; Male; Quinolines; Rats; Rats, Sprague-Dawley; Rutaceae; Sensitivity and Specificity; Tandem Mass Spectrometry | 2013 |
Semisynthesis and insecticidal activity of some fraxinellone derivatives modified in the B ring.
Topics: Animals; Benzofurans; Insecticides; Larva; Molecular Structure; Moths; Structure-Activity Relationship | 2013 |
Effects of Fraxinellone on the midgut enzyme activities of the 5th Instar Larvae of Oriental Armyworm, Mythimna separata walker.
Topics: alpha-Amylases; Animals; Benzofurans; Carboxylesterase; Gastrointestinal Tract; Glutathione Transferase; Insect Proteins; Insecticides; Larva; Lepidoptera; Lipase; NADPH-Ferrihemoprotein Reductase; Peptide Hydrolases | 2014 |
Suppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone.
Topics: Animals; Benzofurans; Cell Line; Colitis; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammasomes; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction | 2014 |
Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping(Antitumor B).
Topics: Alkaloids; Benzofurans; Benzoxepins; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Glucosides; Heterocyclic Compounds, 4 or More Rings; Humans; Limonins; Matrines; Medicine, Chinese Traditional; Permeability; Pterocarpans; Quality Control; Quinolines; Quinolizines; Triterpenes | 2015 |
Semisynthesis of Esters of Fraxinellone C4/10-Oxime and Their Pesticidal Activities.
Topics: Animals; Benzofurans; Crystallography, X-Ray; Esters; Insecticides; Larva; Molecular Structure; Moths; Oximes | 2016 |
CUG-binding protein 1 regulates HSC activation and liver fibrogenesis.
Topics: 3' Untranslated Regions; Animals; Benzofurans; CELF1 Protein; Cells, Cultured; Gene Expression Regulation; Hepatocytes; Humans; Interferon-gamma; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Protein Binding; RNA Interference; RNA, Messenger; Transforming Growth Factor beta | 2016 |
The inhibitory effect in Fraxinellone on oxidative stress-induced senescence correlates with AMP-activated protein kinase-dependent autophagy restoration.
Topics: Adenosine Monophosphate; Aging; AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Benzofurans; beta-Galactosidase; Cellular Senescence; Gene Expression Regulation; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; NIH 3T3 Cells; Oxidative Stress; Protein Kinases | 2018 |
Fraxinellone Attenuates Rheumatoid Inflammation in Mice.
Topics: Animals; Antigens, CD19; Antirheumatic Agents; Arthritis, Rheumatoid; B-Lymphocytes; Benzofurans; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytidine Deaminase; Humans; Ice; Interleukin-17; Male; Mice, Inbred DBA; Nuclear Receptor Subfamily 1, Group F, Member 3; Osteoclasts; Positive Regulatory Domain I-Binding Factor 1; Tartrate-Resistant Acid Phosphatase | 2018 |
Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma.
Topics: Animals; Benzofurans; Cancer Vaccines; Cancer-Associated Fibroblasts; Cell Line, Tumor; Disease Models, Animal; Emulsions; Immunologic Factors; Melanoma; Mice; Nanoparticles; Treatment Outcome; Tumor Microenvironment | 2018 |
Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3.
Topics: Animals; Antineoplastic Agents; B7-H1 Antigen; Benzofurans; Cell Line, Tumor; Cell Movement; Female; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Neoplasms; STAT3 Transcription Factor | 2018 |
Subchronic Toxicity Studies of Cortex Dictamni Extracts in Mice and Its Potential Hepatotoxicity Mechanisms in Vitro.
Topics: Animals; Apoptosis; Benzofurans; Benzoxepins; Cell Count; Cell Survival; Chemical and Drug Induced Liver Injury; Dictamnus; Drugs, Chinese Herbal; Ethanol; Female; Hep G2 Cells; Humans; Limonins; Liver; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred ICR; Quinolines; Toxicity Tests, Subchronic; Water | 2018 |
Turning natural products into insecticide candidates: Design and semisynthesis of novel fraxinellone-based N-(1,3-thiazol-2-yl)carboxamides against two crop-threatening insect pests.
Topics: Animals; Benzofurans; Biological Products; Crystallography, X-Ray; Dose-Response Relationship, Drug; Insecticides; Models, Molecular; Molecular Structure; Moths; Structure-Activity Relationship | 2019 |
Fraxinellone inhibits inflammatory cell infiltration during acute pancreatitis by suppressing inflammasome activation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Benzofurans; Cell Movement; Ceruletide; Disease Models, Animal; Female; Humans; Inflammasomes; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophils; Pancreatitis | 2019 |
Sequential Targeting TGF-β Signaling and KRAS Mutation Increases Therapeutic Efficacy in Pancreatic Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apolipoprotein E3; Benzofurans; Drug Administration Schedule; Drug Carriers; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Molecular Targeted Therapy; Mutation; Nanoparticles; NIH 3T3 Cells; Pancreatic Neoplasms; Peptide Fragments; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Semi-Synthesis of C-Ring Cyclopropyl Analogues of Fraxinellone and Their Insecticidal Activity Against
Topics: Animals; Benzofurans; Insecticides; Molecular Structure; Moths | 2020 |
Spectroscopy, Thermodynamics and Molecular Docking of Fraxinellone with DNA.
Topics: Animals; Benzofurans; Biological Control Agents; Calorimetry; DNA; Insecticides; Molecular Docking Simulation; Moths; Spectrum Analysis; Thermodynamics | 2020 |
Cytochrome P450-Mediated Bioactivation: Implication for the Liver Injury Induced by Fraxinellone, A Bioactive Constituent from Dictamni Cortex.
Topics: Activation, Metabolic; Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzofurans; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dictamnus; Female; Liver; Male; Mice, Inbred ICR; Recombinant Proteins | 2020 |
Toxicology study of fraxinellone as ovicidal agents against Mythimna separata Walker and Bombyx mori Linaeus.
Topics: Animal Shells; Animals; Benzofurans; Bombyx; Crystallography, X-Ray; Insecticides; Larva; Lepidoptera; Meliaceae; Molecular Structure; Plant Extracts; Rutaceae; Species Specificity | 2020 |
Fraxinellone alleviates inflammation and promotes osteogenic differentiation in lipopolysaccharide-stimulated periodontal ligament stem cells by regulating the bone morphogenetic protein 2/Smad pathway.
Topics: Benzofurans; Bone Morphogenetic Protein 2; Cell Differentiation; Cells, Cultured; Humans; Inflammation; Lipopolysaccharides; Osteogenesis; Periodontal Ligament; Signal Transduction; Smad Proteins; Stem Cells | 2021 |
Fraxinellone alleviates kidney fibrosis by inhibiting CUG-binding protein 1-mediated fibroblast activation.
Topics: Animals; Benzofurans; CELF1 Protein; Cell Line; Disease Models, Animal; Fibroblasts; Fibrosis; Folic Acid; JNK Mitogen-Activated Protein Kinases; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Rats; Transforming Growth Factor beta1 | 2021 |
Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer.
Topics: Alkaloids; Animals; Benzofurans; Biological Availability; Chemoprevention; Drugs, Chinese Herbal; Matrines; Mice; Mice, Inbred C57BL; Molecular Structure; Mouth Neoplasms; Network Pharmacology; Pterocarpans; Quinolines; Quinolizines | 2021 |
Fraxinellone ameliorates intracerebral hemorrhage-induced secondary brain injury by regulating Krüppel-like transcription factor 2 expression in rats.
Topics: Animals; Benzofurans; Brain Edema; Brain Injuries; Cerebral Hemorrhage; Disease Models, Animal; Endothelial Cells; Kruppel-Like Transcription Factors; Rats; Rats, Sprague-Dawley | 2021 |
Fraxinellone Induces Hepatotoxicity in Zebrafish through Oxidative Stress and the Transporters Pathway.
Topics: Amino Acids; Animals; Benzofurans; Chemical and Drug Induced Liver Injury; Larva; Liver; Oxidative Stress; Zebrafish | 2022 |
Fraxinellone inhibits progression of glioblastoma via regulating the SIRT3 signaling pathway.
Topics: Adult; Animals; Apoptosis; Benzofurans; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Reactive Oxygen Species; Signal Transduction; Sirtuin 3 | 2022 |