Page last updated: 2024-08-18

framycetin and paromomycin

framycetin has been researched along with paromomycin in 199 studies

Research

Studies (199)

TimeframeStudies, this research(%)All Research%
pre-1990106 (53.27)18.7374
1990's18 (9.05)18.2507
2000's42 (21.11)29.6817
2010's27 (13.57)24.3611
2020's6 (3.02)2.80

Authors

AuthorsStudies
Alborn, WE; Allen, NE; Kirst, HA; Toth, JE1
Cedergren, R; Leclerc, F1
Cashman, DJ; Kellogg, GE; Rife, JP1
Baboolal, N; Tok, JB; Wong, W1
Dabrowiak, JC; Goodisman, J; Sullivan, JM1
Rando, RR; Ryu, DH2
Detering, C; Varani, G1
Hines, JV; Means, JA1
Dabour, N; Fliss, I; Kheadr, E; Lacroix, C; Le Lay, C1
Avison, MB; Okazaki, A1
Arakawa, Y; Ike, Y; Kimura, K; Kurokawa, H; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K1
Inaoka, T; Ochi, K; Okamoto, S; Wang, G1
Aboul-ela, F; Allam, K; Bodoor, K; Boisdore, M; Boyapati, V; Gopu, V; Miller, J; Treleaven, WD; Weldeghiorghis, T1
Altman, RB; Blanchard, SC; Feldman, MB; Terry, DS1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brown, JM; Gonoi, T; Ishikawa, J; Kogure, T; Mikami, Y; Shimada, R; Yazawa, K1
François, B; Giguère, A; Hanessian, S; Kondo, J; Migawa, MT; Pachamuthu, K; Swayze, EE; Szychowski, J; Westhof, E1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Aggen, JB; Armstrong, ES; Dozzo, P; Feeney, LA; Giguère, A; Gliedt, MJ; Goldblum, AA; Grzyb, J; Hanessian, S; Hildebrandt, DJ; Kane, TR; Linsell, MS; Maianti, JP; Matias, RD; Saavedra, OM1
Di Giorgio, A; Duca, M; Tran, TP; Vo, DD1
Chow, CS; Crich, D; Sati, GC; Waduge, P1
Fridman, M; Jospe-Kaufman, M; Siomin, L1
Kondo, S; Matsuhashi, Y; Takeuchi, T; Umezawa, H; Yagisawa, M1
Witchitz, JL1
Rinehart, KL; Stroshane, RM1
Carson, TR; Chung, CW1
DeFuria, MD; Price, KE; Pursiano, TA1
Brumfitt, W; Hamilton-Miller, JM; Reyonolds, AV1
Palmer, E; Wilhelm, JM1
Ball, AP; Gray, JA; Murdoch, JM1
Ganelin, VL; Mogilevichik, LE; Navashin, SM; Razlogova, IO; Sazykin, IuO1
Cousin, MA; Lando, D; Ojasoo, T; Raynaud, JP1
Linnane, AW; Nagley, P; Spithill, TW1
Capmeau, ML; Hanessian, S; Massé, R1
Demina, AS; Ganelin, VL; Griaznova, NS; Sazykin, IuO1
Badalian, K; Der-Sarkissian, M; Sabetzadeh, H1
Gerlach, JH; Rank, GH; Robertson, AJ1
Jennings, BR; Morris, VJ; O'Grady, F; Pearson, NJ1
Acar, JF; Goldstein, F; Le Goffic, F; Talbot, JN; Witchitz, JL1
Baca, B; Dublanchet, A; Duval, J; Le Goffic, F; Soussy, CJ1
Dumbovich, I; Gadó, I1
Kondo, S; Umezawa, H1
Rosaschino, F1
Testa, RT; Tilley, BC1
Hanessian, S; Masse, R; Takamoto, T1
Birt, LM; Williams, KL1
Brown, EM; Butters, RR; Chen, CJ; Katz, CL1
Davies, J; Salauze, D1
Ficker, L; Seal, D; Warhurst, D; Wright, P1
Le, TD; Matoba, AY; Osato, MS; Pare, PD1
Kobayashi, F; Mitsuhashi, S; Yamaguchi, M1
Kobayashi, F; Mitsuhashi, S; Sato, J; Yamaguchi, M1
Hashimoto, K; Okuno, T; Sawada, Y; Taniyama, H1
Umezawa, S1
Umezawa, H1
Pirilä, L; Pirilä, V1
Hamana, K; Kondo, S; Maeda, K; Mitsuhashi, S; Okanishi, M; Umezawa, H; Utahara, R1
Steinbereithner, K1
Homma, Y; Lin, YC; Omura, S; Yajima, T; Yokoyama, S1
Münchow, P1
Pitton, JS; Roupas, A1
Davies, J; Davis, BD; Gorini, L1
Kunin, CM1
Ing, TS; Metcalfe-Gibson, A; Wilson, DR; Wrong, OM1
Arret, B; Eckert, J1
Breunung, M; Breunung, MM1
Beck, D; Siegenthaler, G; Siegenthaler, W; Weidmann, P1
Charlton, RW1
Prado-Franceschi, J; Vital Brazil, O1
Davey, PJ; Haslam, JM; Linnane, AW1
Sulman, FG; Ziv, G1
Mitsuhashi, S; Tanaka, T; Tsunoda, M1
Kaudewitz, F; Kutzleb, R; Schweyen, RJ1
Benveniste, R; Davies, J2
Godfrey, JC; Price, KE1
Benveniste, R; Brzezinska, M; Daniels, PJ; Davies, J; Weinstein, J1
Simon, HJ1
Kondo, S; Okanishi, K; Umezawa, H; Utahara, R1
Masukawa, H; Tanaka, N1
Koch, H; Köditz, H; Lemmer, I; Linde, K1
Passent, J1
Chabbert, YA; Witchitz, JL1
Finegold, SM; Sutter, VL1
Quesnel, LB; Skinner, VM; York, P1
Jedlicková, Z; Sulová, J1
Hussain, HS; Quesnel, LB1
Faloon, WW; Haro, EN; Nankin, H; Paes, IC; Wallace, K; Woolfolk, D1
Hashimoto, H; Mitsuhashi, S; Nagai, Y; Tanaka, T1
Moorhead, PJ; Parry, HE1
Lacey, RW1
Výmola, F1
Hájková, L; Hejzlar, M; Jerábková, V; Paroubek, M; Safránková, M1
Berk, DP; Chalmers, T1
Hessler, EJ; Jahnke, HK; Rinehart, KJ; Robertson, JH; Shier, WT; Tsuji, K1
Despeignes, J; Garin, JP; Vincent, G1
Inouye, S; Niida, T; Omoto, S1
Davies, J; Davis, BD1
Neal, RA1
Bilalis, D; Daikos, G; Kontomichalou, P1
Barthélémy, P; Nominé, G; Pénasse, L1
Carrozzo, M; De Vanna, F; Pipitone, V; Russo, R1
Thrum, H; Triebel, H; Zimmer, C1
Ghione, M1
Kawaguchi, H; Naito, T; Nakagawa, S; Toda, S1
Fang, JR; Pearce, CJ; Rinehart, KL1
Brunner, G1
Daschner, F; Kölle, EU; Lentzen, H1
Autissier, D; Barthelemy, P; Mazieres, N; Penasse, L; Peyre, M1
Fukushima, K; Ito, A; Odagiri, S; Tarao, K; Yamazaki, R1
Croft, SL; Lawrence, F; Maarouf, M; Robert-Gero, M1
Gomez-Lus, R; Vergara, Y1
Clouet-d'Orval, B; Stage, TK; Uhlenbeck, OC1
Anderson, NH; Erwin, PJ; Gardiner, KR; Halliday, MI; McCaigue, MD; Rowlands, BJ1
Brogden, RN; Gillis, JC1
Brown, S; Lawrence, F; Maarouf, M; Robert-Gero, M1
Brown, S; de Kouchkovsky, Y; Maarouf, M; Petit, PX; Robert-Gero, M1
Chen, Q; Kuntz, ID; Shafer, RH1
Famulok, M; Schroeder, R; von Ahsen, U; Wallis, MG1
Greenberg, WA; Hendrix, M; Priestley, ES; Wong, CH1
Brännvall, M; Kirsebom, LA; Mikkelsen, NE; Virtanen, A1
Cho, J; Rando, RR1
Bourdeau, V; Cedergren, R; Ferbeyre, G; Pageau, M; Paquin, B1
Bedwell, DM; Keeling, K; Manuvakhova, M1
Drainas, D; Stathopoulos, C; Tekos, A; Tsagla, A1
Lynch, SR; Puglisi, JD1
Hendrix, M; Joyce, GF; Priestley, ES; Wong, CH1
Fuhrmann, M; Hegemann, P; Sizova, I1
Baker, NA; Joseph, S; Ma, C; McCammon, JA1
Champney, WS; Mehta, R2
Kaul, M; Pilch, DS1
Angelet, P; Bartolomé, J; Cid, JL; Compte, MT; Soriano, T; Vilaseca, J1
Litovchick, A; Rando, RR; Ryu, DH1
Dumas, P; Ehresmann, B; Ehresmann, C; Ennifar, E; Marquet, R; Paillart, JC; Walter, P1
Barbieri, CM; Kaul, M; Kerrigan, JE; Pilch, DS2
Shah, NP; Tharmaraj, N1
FINLAND, M; KUNIN, CM1
FINLAND, M; KUNIN, CM; NAJARIAN, A; WILCOX, C1
FINEGOLD, SM; GAYLOR, DW1
HARRISON, PM; STEWART, GT1
PIRILA, V; ROUHUNKOSKI, S1
SIMONS, RD1
YOW, EM; YOW, MD1
BERTAZZOLI, C; DI MARCO, A1
HEJZLAR, M; JELINEK, J; VYMOLA, F1
BHAT, KM; COLES, HM; HOLT, RJ; STEWART, GT1
INOUYE, S; OGAWA, H1
HOLTZMAN, CM; SAMUEL, P; SHALCHI, OB1
KONDO, S; SEZAKI, M; SHIMURA, M1
WHITE, HL; WHITE, JR1
ALTEMEIER, WA; HILL, EO; HUMMEL, RP1
WAGMAN, GH; WEINSTEIN, MJ1
BILLE, B; MELLBIN, T; NORDBRING, F1
HUETTENRAUCH, R1
Borkow, G; Kalinkovich, A; Lapidot, A; Lara, HH; Vijayabaskar, V1
Barbieri, CM; Fan, Y; Gaffney, BL; Jones, RA; Li, TK; Lin, HC; Pilch, DS; Rabson, AB; Yang, G1
Himeno, H; Konno, T; Kurita, D; Muto, A; Takahashi, T1
James, TL; Lapidot, A; Litovchick, A; Vijayabaskar, V; Yu, J1
Blount, KF; Hermann, T; Tor, Y; Zhao, F1
Choi, GJ; Jung, HS; Kim, CJ; Kim, JC; Kim, Y; Lee, HB; Park, SH1
Aboul-ela, F; François, B; Masquida, B; Murray, JB; Russell, RJ; Vicens, Q; Westhof, E1
Han, KC; Yang, EG; Yu, J1
Tor, Y1
Jobson, A; Liao, Z; Pommier, Y; Thibaut, L1
Kwong, D; Tam, VK; Tor, Y1
Chao, PW; Chow, CS1
Kirsebom, LA; Thuresson, AC; Virtanen, A1
Borovinskaya, MA; Cate, JH; Hirokawa, G; Holton, JM; Kaji, A; Kaji, H; Pai, RD; Schuwirth, BS; Zhang, W1
Li, H; Ortego, BC; Tu, SC; Whittenton, JJ; Willson, RC1
Champney, WS; Foster, C1
Andreasen, KF; Arya, DP; Hyde-Volpe, D; Kumar, S; Ranjan, N1
Dix, AV; Esko, JD; Fischer, L; Redgate, CP; Sarrazin, S; Tor, Y1
Cowan, JA; Patwardhan, A1
Clausnitzer, D; Piepersberg, W; Wehmeier, UF1
Arya, DP; Davis, E; Hyde-Volpe, D; Ranjan, N; Xi, H; Xue, L1
Norris, AL; Serpersu, EH1
Armstrong, ES; Feeney, LA; Hanessian, S; Maianti, JP; Matias, RD1
Chatin, B; Hauchecorne, M; Lambert, O; Lehn, JM; Lehn, P; Mével, M; Oudrhiri, N; Pitard, B; Sainlos, M; Vigneron, JP1
Catala, M; Dardel, F; Larue, V; Lecourt, T; Lombès, T; Micouin, L; Moumné, R; Prost, E; Tisné, C1
Nickels, J; Norris, AL; Serpersu, EH; Sokolov, AP1
Altman, RB; Blanchard, SC; Cate, JH; Garneau-Tsodikova, S; Green, KD; Pulk, A; Wasserman, MR; Zhou, Z; Zinder, JC1
Adir, N; Baasov, T; Belakhov, V; Jaffe, CL; Kopelyanskiy, D; Nasereddin, A; Rozenberg, H; Schacht, J; Schrepfer, T; Shalev, M; Smolkin, B1
Alguacil, J; Bosch, E; Ràfols, C; Robles, J1
Böttger, EC; Crich, D; Hobbie, SN; Sati, GC; Shcherbakov, D; Vasella, A1
Böttger, EC; Crich, D; Hobbie, SN; Kato, T; Mandhapati, AR; Shcherbakov, D; Vasella, A; Yang, G1
Ehrenberg, M; Pavlov, MY; Zhang, J1
Kulik, M; Mori, T; Sugita, Y; Trylska, J1
Bofill-Bosch, C; Boussebayle, A; Braun, J; Dombrowski, M; Groher, F; Hamacher, K; Ollivaud, S; Suess, B; Torka, D1
Böttger, EC; Crich, D; Furukawa, T; Hobbie, SN; Mantovani, M; Mondal, S; Sarpe, VA; Sati, GC; Vasella, A1
Crich, D; Sonousi, A; Vasella, A1
Belardinelli, R; Peske, F; Rodnina, MV; Sharma, H1
Blanc, A; Loidon, H; Obszynski, J; Pale, P; Weibel, JM1
Breuker, K; Palasser, M1
Alekseeva, MG; Danilenko, VN; Mavletova, DA; Ratkin, AV; Rudakova, NN1

Reviews

15 review(s) available for framycetin and paromomycin

ArticleYear
The relationship between the structure and toxicity of aminoglycoside antibiotics.
    Bioorganic & medicinal chemistry letters, 2020, 07-01, Volume: 30, Issue:13

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; Ear, Inner; Epithelial Cells; Humans; Kidney Tubules; Molecular Structure

2020
Antibacterial Drugs today: II.
    Drugs, 1975, Volume: 10, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Cephalexin; Cephaloridine; Cephalosporins; Cephalothin; Cephamycins; Cephradine; Framycetin; Gentamicins; Humans; Kanamycin; Neomycin; Paromomycin; Polymyxins; Streptomycin; Tobramycin

1975
[Antistaphylococcal activity of gentamicin].
    Minerva medica, 1975, Dec-08, Volume: 66, Issue:84

    Topics: Cephalosporins; Cross Infection; Drug Resistance, Microbial; Framycetin; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Neomycin; Paromomycin; Rifampin; Staphylococcal Infections; Staphylococcus; Streptomycin; Virginiamycin

1975
Structures and syntheses of aminoglycoside antibiotics.
    Advances in carbohydrate chemistry and biochemistry, 1974, Volume: 30

    Topics: Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Gentamicins; Hygromycin B; Kanamycin; Neomycin; Paromomycin; Ribostamycin; Sisomicin; Streptomycin; Structure-Activity Relationship; Tobramycin

1974
Biochemical mechanism of resistance to aminoglycosidic antibiotics.
    Advances in carbohydrate chemistry and biochemistry, 1974, Volume: 30

    Topics: Adenosine Triphosphate; Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Cyclic AMP; Drug Resistance, Microbial; Escherichia coli; Gentamicins; Kanamycin; Klebsiella pneumoniae; Neomycin; Nucleotidyltransferases; Paromomycin; Phosphotransferases; Pseudomonas aeruginosa; Staphylococcus; Streptomycin; Structure-Activity Relationship

1974
[Antibiotics 19].
    Pharmazeutische Praxis, 1967, Volume: 11

    Topics: Ampicillin; Anti-Bacterial Agents; Bacitracin; Chemical Phenomena; Chemistry; Chloramphenicol; Dihydrostreptomycin Sulfate; Erythromycin; Humans; Kanamycin; Methicillin; Neomycin; Novobiocin; Oleandomycin; Oxytetracycline; Paromomycin; Penicillin G; Penicillin V; Polymyxins; Rolitetracycline; Streptomycin; Tetracycline

1967
Nephrotoxicity of antibiotics.
    JAMA, 1967, Oct-16, Volume: 202, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Bacitracin; Child; Child, Preschool; Colistin; Humans; Kanamycin; Kidney; Neomycin; Paromomycin; Peritoneal Dialysis; Polymyxins; Renal Dialysis; Tetracycline; Uremia

1967
Recent advances in antibiotics.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Mar-15, Volume: 43, Issue:11

    Topics: Anti-Bacterial Agents; Antifungal Agents; Cephaloridine; Chloramphenicol; Colistin; Erythromycin; Fusidic Acid; Gentamicins; Humans; Kanamycin; Lincomycin; Neomycin; Novobiocin; Paromomycin; Penicillins; Polymyxins; Streptomycin; Tetracycline

1969
Effect of structural modifications on the biological properties of aminoglycoside antibiotics containing 2-deoxystreptamine.
    Advances in applied microbiology, 1974, Volume: 18, Issue:0

    Topics: Acetyltransferases; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Framycetin; Gentamicins; Humans; Kanamycin; Microbial Sensitivity Tests; Neomycin; Nucleotidyltransferases; Paromomycin; Phosphotransferases; Streptomycin; Structure-Activity Relationship

1974
Streptomycin, kanamycin, neomycin and paromomycin.
    Pediatric clinics of North America, 1968, Volume: 15, Issue:1

    Topics: Anti-Bacterial Agents; Diarrhea; Drug Hypersensitivity; Humans; Kanamycin; Neomycin; Paromomycin; Streptomycin

1968
[The effect of antibiotics on protein synthesis].
    Postepy biochemii, 1969, Volume: 15, Issue:2

    Topics: Anti-Bacterial Agents; Chloramphenicol; Chlortetracycline; Cycloheximide; Erythromycin; Escherichia coli; Fusidic Acid; Genetic Code; Gentamicins; Isoleucine; Kanamycin; Leucine; Lincomycin; Neomycin; Oxytetracycline; Paromomycin; Peptides; Phenylalanine; Protein Biosynthesis; Puromycin; Steroids; Streptomycin; Tetracycline

1969
Rifaximin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria.
    Drugs, 1995, Volume: 49, Issue:3

    Topics: Diarrhea; Diverticulum, Colon; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Hepatic Encephalopathy; Humans; Intestinal Absorption; Lactulose; Neomycin; Paromomycin; Rifamycins; Rifaximin

1995
Thermodynamics of aminoglycoside-rRNA recognition.
    Biopolymers, 2003, Volume: 70, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Calorimetry; Computer Simulation; Databases as Topic; Electrolytes; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Neomycin; Nucleic Acid Conformation; Osmosis; Paromomycin; RNA; RNA, Ribosomal; Salts; Spectrophotometry; Temperature; Thermodynamics

2003
The ribosomal A-site as an inspiration for the design of RNA binders.
    Biochimie, 2006, Volume: 88, Issue:8

    Topics: Anti-Bacterial Agents; Binding Sites; Molecular Structure; Neomycin; Nucleic Acid Conformation; Paromomycin; Ribosomes; RNA, Ribosomal, 16S; Structure-Activity Relationship

2006
Targeted modifications of neomycin and paromomycin: Towards resistance-free antibiotics?
    Bioorganic chemistry, 2022, Volume: 126

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Humans; Neomycin; Paromomycin

2022

Trials

1 trial(s) available for framycetin and paromomycin

ArticleYear
In vivo dialysis of faeces as a method of stool analysis. 3. The effect of intestinal antibiotics.
    Clinical science, 1968, Volume: 34, Issue:1

    Topics: Adult; Ammonia; Anti-Bacterial Agents; Bacitracin; Bacteroides; Carbon Dioxide; Colistin; Dialysis; Enterococcus faecalis; Feces; Female; Humans; Intestines; Male; Methods; Neomycin; Nitrogen; Nystatin; Paromomycin; Phosphates; Polymyxins; Potassium; Sodium; Sulfates; Urea; Urease

1968

Other Studies

183 other study(ies) available for framycetin and paromomycin

ArticleYear
Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Biological Transport; Escherichia coli; Indicators and Reagents; Kinetics; Structure-Activity Relationship

1987
Modeling RNA-ligand interactions: the Rev-binding element RNA-aminoglycoside complex.
    Journal of medicinal chemistry, 1998, Jan-15, Volume: 41, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Antiviral Agents; Binding Sites; Computer Simulation; Crystallography, X-Ray; Gene Products, rev; Humans; Ligands; Macromolecular Substances; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Protein Conformation; Rhinovirus; RNA, Viral; Structure-Activity Relationship

1998
Which aminoglycoside ring is most important for binding? A hydropathic analysis of gentamicin, paromomycin, and analogues.
    Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Escherichia coli; Gentamicins; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Paromomycin; RNA, Ribosomal, 16S; Structure-Activity Relationship; Thermodynamics

2001
Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers.
    Bioorganic & medicinal chemistry letters, 2002, Feb-11, Volume: 12, Issue:3

    Topics: Aminoglycosides; Anisotropy; Anti-Bacterial Agents; Base Pairing; Binding Sites; Cyclization; Drug Design; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; RNA, Complementary; RNA, Ribosomal, 16S; Structure-Activity Relationship

2002
Absorption studies on aminoglycoside binding to the packaging region of human immunodeficiency virus type-1.
    Bioorganic & medicinal chemistry letters, 2002, Feb-25, Volume: 12, Issue:4

    Topics: Anti-Bacterial Agents; Base Sequence; Binding Sites; Dose-Response Relationship, Drug; Framycetin; HIV-1; Humans; Molecular Sequence Data; Neomycin; Nucleic Acid Conformation; Paromomycin; RNA; Spectrum Analysis; Virus Assembly

2002
Decoding region bubble size and aminoglycoside antibiotic binding.
    Bioorganic & medicinal chemistry letters, 2002, Aug-19, Volume: 12, Issue:16

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Fluorescence Polarization; Humans; Molecular Structure; Mutation; Nucleic Acid Conformation; RNA, Ribosomal

2002
Validation of automated docking programs for docking and database screening against RNA drug targets.
    Journal of medicinal chemistry, 2004, Aug-12, Volume: 47, Issue:17

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Databases, Factual; Ligands; Models, Molecular; Nucleic Acid Conformation; Quantitative Structure-Activity Relationship; RNA; RNA, Ribosomal; Software

2004
Fluorescence resonance energy transfer studies of aminoglycoside binding to a T box antiterminator RNA.
    Bioorganic & medicinal chemistry letters, 2005, Apr-15, Volume: 15, Issue:8

    Topics: Aminoglycosides; Bacterial Proteins; Fluorescence Resonance Energy Transfer; RNA-Binding Proteins; RNA, Bacterial; T-Box Domain Proteins

2005
Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Acids; Ampicillin; Anti-Bacterial Agents; Bifidobacterium; Chloramphenicol; Cloxacillin; Culture Media; Drug Resistance, Bacterial; Erythromycin; Hydrogen Peroxide; Microbial Sensitivity Tests; Nisin; Penicillins; Species Specificity; Tetracyclines; Vancomycin

2007
Aph(3')-IIc, an aminoglycoside resistance determinant from Stenotrophomonas maltophilia.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Drug Resistance, Multiple, Bacterial; Escherichia coli; Gram-Negative Bacterial Infections; Humans; Kanamycin; Kanamycin Kinase; Microbial Sensitivity Tests; Mutation; Neomycin; Stenotrophomonas maltophilia

2007
Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Plasmids; Protein Binding; Ribosome Subunits, Small; RNA, Ribosomal, 16S; Sequence Homology, Amino Acid

2007
A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amino Acid Substitution; Anti-Bacterial Agents; Cell-Free System; DNA, Bacterial; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Glycine; Green Fluorescent Proteins; Microbial Sensitivity Tests; Molecular Structure; Mutagenesis, Insertional; Paromomycin; Protein Biosynthesis; Ribosomal Proteins; RNA, Bacterial; Sequence Analysis, DNA; Streptomyces coelicolor

2009
Design and implementation of an ribonucleic acid (RNA) directed fragment library.
    Journal of medicinal chemistry, 2009, Jun-25, Volume: 52, Issue:12

    Topics: Binding Sites; Chemistry, Physical; Databases, Factual; Drug Design; Ligands; Magnetic Resonance Spectroscopy; Molecular Weight; Organic Chemicals; Quality Control; RNA; Small Molecule Libraries

2009
Aminoglycoside activity observed on single pre-translocation ribosome complexes.
    Nature chemical biology, 2010, Volume: 6, Issue:1

    Topics: Aminoglycosides; Binding Sites; Conserved Sequence; Cryoelectron Microscopy; Fluorescence Resonance Energy Transfer; Kanamycin; Kinetics; Models, Molecular; Mutation; Neomycin; Oligonucleotides; Protein Binding; Protein Transport; Reproducibility of Results; Ribosomes; RNA; RNA, Transfer

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Base Sequence; Canada; Cattle; DNA Primers; Drug Resistance, Bacterial; Female; Genes, Bacterial; Homozygote; In Vitro Techniques; Mastitis, Bovine; Microbial Sensitivity Tests; Nocardia; Nocardia Infections; Point Mutation; RNA, Bacterial; RNA, Ribosomal, 16S

2010
Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: a synergistic hydrophobic effect against resistant bacteria.
    Bioorganic & medicinal chemistry letters, 2010, Dec-01, Volume: 20, Issue:23

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria; Crystallization; Drug Design; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; RNA, Ribosomal

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Toward Overcoming Staphylococcus aureus Aminoglycoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue.
    ACS medicinal chemistry letters, 2011, Dec-08, Volume: 2, Issue:12

    Topics:

2011
Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; DEAD-box RNA Helicases; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Models, Molecular; Molecular Sequence Data; Neoplasms; Ribonuclease III; Ribosomes; Tetracyclines

2015
Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites.
    Bioorganic & medicinal chemistry, 2019, 11-15, Volume: 27, Issue:22

    Topics: Aminoglycosides; Bacteria; Binding Sites; Fluorescence; Humans; Mitochondria; RNA

2019
Aminoglycoside 3'-phosphotransferases I and II in Pseudomonas aeruginosa.
    The Journal of antibiotics, 1975, Volume: 28, Issue:6

    Topics: Aminoglycosides; Butirosin Sulfate; Chromatography, Affinity; Escherichia coli; Hydrogen-Ion Concentration; Kanamycin; Molecular Weight; Neomycin; Paromomycin; Phosphotransferases; Pseudomonas aeruginosa

1975
[Mechanisms of inactivation of aminosides. Relationship to phenotype in Gram negative bacilli].
    La Nouvelle presse medicale, 1975, Sep-20, Volume: 4, Issue:30

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Butirosin Sulfate; Drug Resistance, Microbial; Enterobacteriaceae; Framycetin; Gentamicins; Kanamycin; Paromomycin; Phenotype; R Factors; Sisomicin; Structure-Activity Relationship; Tobramycin

1975
Biosynthesis of aminocyclitol antibiotics.
    The Journal of antibiotics, 1976, Volume: 29, Issue:4

    Topics: Anti-Bacterial Agents; Butirosin Sulfate; Cyclohexanols; Gentamicins; Kanamycin; Neomycin; Paromomycin; Ribostamycin; Sisomicin; Spectinomycin; Streptomycin

1976
Cross-sensitivity of common aminoglycoside antibiotics.
    Archives of dermatology, 1976, Volume: 112, Issue:8

    Topics: Aminoglycosides; Animals; Cross Reactions; Dihydrostreptomycin Sulfate; Gentamicins; Guinea Pigs; Humans; Kanamycin; Mycobacterium; Mycobacterium tuberculosis; Neomycin; Paromomycin; Streptomycin; Structure-Activity Relationship

1976
Amikacin, an aminoglycoside with marked activity against antibiotic-resistant clinical isolates.
    The Journal of infectious diseases, 1976, Volume: 134 SUPPL

    Topics: Acinetobacter; Alcaligenes; Amikacin; Bacteria; Butirosin Sulfate; Dibekacin; Drug Resistance, Microbial; Enterobacteriaceae; Flavobacterium; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pseudomonas; Ribostamycin; Staphylococcus; Tobramycin

1976
In vitro activity of amikacin and ten other aminoglycoside antibiotics against gentamicin-resistant bacterial strains.
    The Journal of infectious diseases, 1976, Volume: 134 SUPPL

    Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Butirosin Sulfate; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pseudomonas aeruginosa; Ribostamycin; Sisomicin; Streptomycin; Tobramycin

1976
Mistranslation in a eucaryotic organism.
    Cell, 1978, Volume: 13, Issue:2

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Butirosin Sulfate; Cell-Free System; Gentamicins; Kanamycin; Neomycin; Paromomycin; Protein Biosynthesis; Streptomycin; Tetrahymena

1978
[Isolation, purification and substrate specificity of aminoglycoside phosphotransferase from Escherichia coli 182].
    Doklady Akademii nauk SSSR, 1976, Volume: 230, Issue:5

    Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Molecular Weight; Neomycin; Paromomycin; Phosphotransferases

1976
Stability of 70S ribosomes in relation to misreading and antibacterial activity of aminoglycosides.
    Biochimie, 1977, Volume: 59, Issue:1

    Topics: Aminoglycosides; Binding Sites; Dose-Response Relationship, Drug; Escherichia coli; Kinetics; Muramidase; Neomycin; Paromomycin; Protein Biosynthesis; Ribosomes; Structure-Activity Relationship; Transcription, Genetic

1977
Biogenesis of mitochondria 51: biochemical characterization of a mitochondrial mutation in Saccharomyces cerevisiae affecting the mitochondrial ribosome by conferring resistance to aminoglycoside antibiotics.
    Molecular & general genetics : MGG, 1979, Jun-07, Volume: 173, Issue:2

    Topics: DNA, Mitochondrial; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Mutation; Neomycin; Paromomycin; Phenotype; Ribosomes; RNA, Bacterial; RNA, Fungal; RNA, Messenger; Saccharomyces cerevisiae

1979
Aminoglycoside antibiotics: synthesis of 5''-amino-5''-deoxyneomycin and 5''-amino-5''-deoxyparomomycin.
    The Journal of antibiotics, 1977, Volume: 30, Issue:10

    Topics: Bacteria; Neomycin; Paromomycin; Structure-Activity Relationship

1977
[Isolation and substrate specificity of neomycin (paromomycin)--phosphotransferase from Actinomyces fradiae, a producer of neomycin].
    Antibiotiki, 1977, Volume: 22, Issue:12

    Topics: Adenosine Triphosphate; Enzyme Activation; Magnesium; Neomycin; Oxidative Phosphorylation; Paromomycin; Phosphotransferases; Streptomyces; Substrate Specificity; Time Factors

1977
Relation between Salmonella typhimurium biotypes and drug resistance, Teheran, Iran (1962-1973).
    The Journal of tropical medicine and hygiene, 1976, Volume: 79, Issue:2

    Topics: Ampicillin; Anti-Bacterial Agents; Cephalothin; Chloramphenicol; Colistin; Drug Combinations; Furazolidone; Kanamycin; Nalidixic Acid; Neomycin; Paromomycin; Penicillin Resistance; Salmonella typhimurium; Streptomycin; Sulfamethoxazole; Sulfonamides; Tetracycline; Trimethoprim

1976
Some physiological alteration associated with pleiotropic cross resistance and collateral sensitivity in Saccharomyces cerevisiae.
    Molecular & general genetics : MGG, 1976, Mar-30, Volume: 144, Issue:3

    Topics: Alleles; Antimycin A; Cerulenin; Chloramphenicol; Cycloheximide; Dequalinium; Drug Resistance, Microbial; Gentamicins; Mutation; Neomycin; Oligomycins; Paromomycin; Phenotype; Saccharomyces cerevisiae; Species Specificity; Tetracycline; Triethyltin Compounds; Trityl Compounds

1976
An electro-optic study of the effect of certain aminoglycoside antibiotics on the electrical polarizability of sensitive, dependent and resistant strains of Escherichia coli.
    Microbios, 1976, Volume: 17, Issue:68-69

    Topics: Anti-Bacterial Agents; Cell Membrane; Drug Resistance, Microbial; Electrophysiology; Escherichia coli; Framycetin; Gentamicins; Mathematics; Neomycin; Paromomycin; Sisomicin; Species Specificity; Streptomycin

1976
Suceptibility of aminoglycoside-resistant gram-negative bacilli to amikacin: delineation of individual resistance patterns.
    The Journal of infectious diseases, 1976, Volume: 134 SUPPL

    Topics: Amikacin; Aminoglycosides; Drug Resistance, Microbial; Enterobacteriaceae; Gentamicins; Kanamycin; Moraxella; Neomycin; Paromomycin; Pseudomonas aeruginosa; Tobramycin

1976
[ANT(4')I: a new aminoglycoside nucleotidyltransferase found in "staphylococcus aureus" (author's transl)].
    Annales de microbiologie, 1976, Volume: 127, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Kanamycin; Neomycin; Nucleotidyltransferases; Paromomycin; Staphylococcus aureus; Tobramycin

1976
Effect of some aminoglycosides upon a drug dependent Escherichia coli strain.
    Acta microbiologica Academiae Scientiarum Hungaricae, 1975, Volume: 22, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Cell Count; Cell Survival; Drug Antagonism; Drug Resistance, Microbial; Escherichia coli; Ethanol; Gentamicins; Kanamycin; Methanol; Microbial Sensitivity Tests; Mutagens; Mutation; Neomycin; Nitrosoguanidines; Paromomycin; Streptomycin

1975
Ion-exchange chromatography of aminoglycoside antibodies.
    Methods in enzymology, 1975, Volume: 43

    Topics: Aminoglycosides; Anti-Bacterial Agents; Biological Assay; Chromatography, Ion Exchange; Gentamicins; Kanamycin; Klebsiella pneumoniae; Nebramycin; Neomycin; Paromomycin; Streptomyces

1975
Biotransformation, a new approach to aminoglycoside biosynthesis. I. Sisomicin.
    The Journal of antibiotics, 1975, Volume: 28, Issue:8

    Topics: Aminoglycosides; Anti-Bacterial Agents; Biotransformation; Chemical Phenomena; Chemistry; Disaccharides; Gentamicins; Micromonospora; Neomycin; Paromomycin; Sisomicin; Trisaccharides

1975
Aminoglycoside antibiotics: oxidative degradations leading to novel biochemical probes and synthetic intermediates.
    The Journal of antibiotics, 1975, Volume: 28, Issue:10

    Topics: Aminoglycosides; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Neomycin; Oxidation-Reduction; Paromomycin

1975
Effect of antibacterial inhibitors on protein synthesis in isolated flight muscle mitochondria of the blowfly Lucilia cuprina: phylogenetic implications.
    FEBS letters, 1976, Jul-01, Volume: 66, Issue:1

    Topics: Animals; Chloramphenicol; Cycloheximide; Diptera; Kanamycin; Lincomycin; Mitochondria, Muscle; Muscle Proteins; Neomycin; Oleandomycin; Paromomycin; Ribosomes; Species Specificity

1976
Structure-function relationships for the effects of various aminoglycoside antibiotics on dispersed bovine parathyroid cells.
    Endocrinology, 1992, Volume: 131, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Calcium; Cattle; Cyclic AMP; Dopamine; Framycetin; Gentamicins; Parathyroid Glands; Parathyroid Hormone; Paromomycin; Structure-Activity Relationship; Tobramycin

1992
Transcriptional mapping of the promoter of the aminoglycoside acetyltransferase gene (aacC9) of neomycin-producing Micromonospora chalcea.
    Research in microbiology, 1992, Volume: 143, Issue:2

    Topics: Acetyltransferases; Chromosome Mapping; In Vitro Techniques; Micromonospora; Neomycin; Paromomycin; Promoter Regions, Genetic; Streptomyces; Transcription, Genetic

1992
Acanthamoeba keratitis--resistance to medical therapy.
    Eye (London, England), 1990, Volume: 4 ( Pt 6)

    Topics: Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Arsenicals; Benzamidines; Benzethonium; Clotrimazole; Corneal Transplantation; Drug Resistance; Drug Therapy, Combination; Humans; Male; Neomycin; Paromomycin; Phenanthridines; Recurrence; Temperature

1990
The effects of freezing and antibiotics on the viability of Acanthamoeba cysts.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1989, Volume: 107, Issue:3

    Topics: Acanthamoeba; Animals; Anti-Bacterial Agents; Benzamidines; Cryosurgery; Evaluation Studies as Topic; Neomycin; Paromomycin

1989
Phosphorylated inactivation of aminoglycosidic antibiotics by Pseudomonas aeruginosa.
    Japanese journal of microbiology, 1971, Volume: 15, Issue:3

    Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Dihydrostreptomycin Sulfate; Drug Resistance, Microbial; Gentamicins; Glycosides; Kanamycin; Neomycin; Oxidative Phosphorylation; Paromomycin; Pseudomonas aeruginosa

1971
Purification and properties of dihydrostreptomycin-phosphorylating enzyme from Pseudomonas aeruginosa.
    Japanese journal of microbiology, 1972, Volume: 16, Issue:1

    Topics: Adenosine Triphosphate; Chromatography, Gel; Dihydrostreptomycin Sulfate; Drug Resistance, Microbial; Gentamicins; Hydrogen-Ion Concentration; Kanamycin; Magnesium; Neomycin; Paromomycin; Phosphorylase Kinase; Pseudomonas aeruginosa

1972
[Separation and purification of water-soluble basic antibiotics by using microcrystalline cellulose "Avicel"].
    The Japanese journal of antibiotics, 1972, Volume: 25, Issue:2

    Topics: Amino Sugars; Animals; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Capreomycin; Cellulose; Chromatography; Chromatography, Thin Layer; Dihydrostreptomycin Sulfate; Female; Fungi; Gentamicins; Kanamycin; Mice; Neomycin; Paromomycin; Peptides; Solubility; Spectrophotometry, Infrared; Streptomycin; Viomycin; Water

1972
Sensitization to the neomycin group of antibiotics. Patterns of cross-sensitivity as a function of polyvalent sensitization to different portions of the neomycin molecule.
    Acta dermato-venereologica, 1966, Volume: 46, Issue:6

    Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Cyclohexanes; Humans; Hypersensitivity, Immediate; Kanamycin; Neomycin; Paromomycin; Rubber; Skin Tests

1966
Phosphorylative inactivation of aminoglycosidic antibiotics by Escherichia coli carrying R factor.
    Science (New York, N.Y.), 1967, Sep-29, Volume: 157, Issue:3796

    Topics: Adenosine Triphosphate; Alkaline Phosphatase; Anti-Bacterial Agents; Chromatography, Ion Exchange; Dihydrostreptomycin Sulfate; Drug Resistance, Microbial; Escherichia coli; Glucosamine; Glycosides; Hexoses; Hydrogen-Ion Concentration; Kanamycin; Neomycin; Paromomycin; Phosphates

1967
[The synergistic action of certain antibiotics with curariform muscle relaxants].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1967, Volume: 23, Issue:1

    Topics: Anti-Bacterial Agents; Bacitracin; Dihydrostreptomycin Sulfate; Drug Synergism; Humans; Kanamycin; Muscles; Neomycin; Paromomycin; Penicillins; Polymyxins; Streptomycin; Tetracycline; Viomycin

1967
Screening of antimycoplasma antibiotics.
    The Journal of antibiotics, 1967, Volume: 20, Issue:5

    Topics: Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Azaserine; Cycloserine; Dactinomycin; Dihydrostreptomycin Sulfate; Kanamycin; Leucomycins; Mitomycins; Mycoplasma; Neomycin; Oligomycins; Paromomycin; Polymyxins; Streptomyces

1967
[New profile of a resistance to aminoglycosides in Pseudomonas aeruginosa].
    Pathologia et microbiologia, 1974, Volume: 40, Issue:3

    Topics: Acetyl Coenzyme A; Acetylesterase; Adenosine Triphosphate; Aminoglycosides; Anti-Bacterial Agents; Carbon Radioisotopes; Cell-Free System; Drug Resistance, Microbial; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pseudomonas aeruginosa; Streptomycin

1974
Misreading of RNA codewords induced by aminoglycoside antibiotics.
    Molecular pharmacology, 1965, Volume: 1, Issue:1

    Topics: Adenine Nucleotides; Anti-Bacterial Agents; Cytosine Nucleotides; Genetic Code; Gentamicins; In Vitro Techniques; Kanamycin; Kinetics; Lysine; Neomycin; Nucleotides; Paromomycin; Peptide Biosynthesis; Polynucleotides; Proline; RNA, Transfer; Streptomycin; Uracil Nucleotides; Viomycin

1965
New developments in antibiotic interference thresholds of microbial assays.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:5

    Topics: Anti-Bacterial Agents; Bacitracin; Biological Assay; Chloramphenicol; Colistin; Cycloserine; Erythromycin; Kanamycin; Neomycin; Novobiocin; Oleandomycin; Paromomycin; Penicillins; Polymyxins; Streptomycin; Tetracycline; Viomycin

1968
[Attempts at eradication of salmonella enteritis infections in children].
    Medizinische Klinik, 1967, Mar-10, Volume: 62, Issue:10

    Topics: Anti-Bacterial Agents; Carrier State; Child; Child, Preschool; Chloramphenicol; Cycloserine; Enteritis; Feces; Furazolidone; Humans; Infant; Neomycin; Niacinamide; Nitrofurantoin; Paromomycin; Penicillins; Polymyxins; Salmonella; Salmonella Infections; Streptomycin; Sulfaguanidine; Sulfonamides; Tetracycline

1967
[New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol].
    Antibiotica et chemotherapia. Fortschritte. Advances. Progres, 1968, Volume: 14

    Topics: Anti-Bacterial Agents; Cephalosporins; Chemistry, Pharmaceutical; Erythromycin; Fusidic Acid; Gentamicins; Kanamycin; Leucomycins; Lincomycin; Neomycin; Novobiocin; Oleandomycin; Paromomycin; Polymyxins; Rifampin; Ristocetin; Spectinomycin; Vancomycin; Virginiamycin

1968
The neuromuscular blocking action of gentamicin.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Blood Pressure; Calcium; Cats; Columbidae; Diaphragm; Gallamine Triethiodide; Gentamicins; Kanamycin; Neomycin; Neostigmine; Neuromuscular Junction; Paralysis; Paromomycin; Phrenic Nerve; Rats; Streptomycin; Synaptic Transmission; Tetany

1969
Biogenesis of mitochondria. 12. The effects of aminoglycoside antibiotics on the mitochondrial and cytoplasmic protein-synthesizing systems of Saccharomyces cerevisiae.
    Archives of biochemistry and biophysics, 1970, Volume: 136, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Carbon Isotopes; Cell Membrane Permeability; Depression, Chemical; Glucose; Glycerol; Glycosides; Kanamycin; Leucine; Mitochondria; Mitochondria, Liver; Neomycin; Paromomycin; Protein Biosynthesis; Rats; Ribosomes; Saccharomyces; Species Specificity; Streptomycin; Viomycin

1970
Distribution of aminoglycoside antibiotics in blood and milk.
    Research in veterinary science, 1974, Volume: 17, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cattle; Female; Gentamicins; Half-Life; Injections, Intramuscular; Injections, Intravenous; Kanamycin; Lactation; Mastitis, Bovine; Milk; Neomycin; Paromomycin; Pregnancy; Sheep

1974
Distribution of R factors among Shigella strains isolated in Japan (II).
    Japanese journal of microbiology, 1973, Volume: 17, Issue:4

    Topics: Ampicillin; Cephaloridine; Chloramphenicol; Colistin; Extrachromosomal Inheritance; Furazolidone; Gentamicins; Japan; Kanamycin; Nalidixic Acid; Neomycin; Paromomycin; Penicillin Resistance; Serotyping; Shigella; Streptomycin; Sulfanilamides; Tetracycline

1973
Extrachromosomal inheritance of paromomycin resistance in Saccharomyces cerevisiae. Genetic and biochemical characterization of mutants.
    Molecular & general genetics : MGG, 1973, Sep-05, Volume: 125, Issue:1

    Topics: Carbon Radioisotopes; Chromosomes; Cross Reactions; Crosses, Genetic; Drug Resistance, Microbial; Ethidium; Extrachromosomal Inheritance; Haploidy; Mitochondria; Mitosis; Mutation; Neomycin; Paromomycin; Phenylalanine; Saccharomyces cerevisiae; Time Factors

1973
Structure-activity relationships among the aminoglycoside antibiotics: role of hydroxyl and amino groups.
    Antimicrobial agents and chemotherapy, 1973, Volume: 4, Issue:4

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; Escherichia coli; Glycosides; Kanamycin; Neomycin; Paromomycin; Structure-Activity Relationship

1973
Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moiety.
    Biochemistry, 1972, Feb-29, Volume: 11, Issue:5

    Topics: Acylation; Acyltransferases; Amino Sugars; Anti-Bacterial Agents; Carbon Isotopes; Cell-Free System; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Gentamicins; Glycosides; Hydrolysis; Kanamycin; Neomycin; Paromomycin; Peptides; Pseudomonas aeruginosa; Structure-Activity Relationship

1972
Drug-induced deafness.
    JAMA, 1973, Apr-23, Volume: 224, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Aspirin; Deafness; Drug-Related Side Effects and Adverse Reactions; Ethacrynic Acid; Gentamicins; Glycosides; Humans; Injections, Intravenous; Kanamycin; Male; Middle Aged; Neomycin; Paromomycin; Quinidine

1973
Phosphorylation and inactivation of aminoglycosidic antibiotics by E. coli carrying R factor.
    The Journal of antibiotics, 1968, Volume: 21, Issue:1

    Topics: Adenosine Triphosphate; Alkaline Phosphatase; Anti-Bacterial Agents; Culture Media; Drug Resistance, Microbial; Escherichia coli; Kanamycin; Magnesium; Neomycin; Paromomycin; Phosphates; Shigella sonnei; Streptomycin

1968
Miscoding activity of amino sugars.
    The Journal of antibiotics, 1968, Volume: 21, Issue:1

    Topics: Amino Acids; Amino Sugars; Anti-Bacterial Agents; Carbon Isotopes; Chemical Phenomena; Chemistry; DNA, Bacterial; Escherichia coli; Gentamicins; Kanamycin; Neomycin; Paromomycin; Peptide Biosynthesis; Polynucleotides; Protein Biosynthesis; Ribosomes; RNA, Bacterial; Streptomycin

1968
[Effect of paromomycin on enterobacteriaceae in well and from coli-enteritis suffering infants].
    Zeitschrift fur Kinderheilkunde, 1968, Volume: 102, Issue:2

    Topics: Drug Resistance, Microbial; Enteritis; Enterobacteriaceae; Escherichia coli; Escherichia coli Infections; Feces; Humans; Infant; Neomycin; Paromomycin

1968
High level transferable resistance to gentamicin.
    The Journal of antibiotics, 1971, Volume: 24, Issue:2

    Topics: Drug Resistance, Microbial; Enterobacteriaceae; Erythromycin Ethylsuccinate; Escherichia coli; Framycetin; Gentamicins; Kanamycin; Klebsiella; Microbial Sensitivity Tests; Neomycin; Paromomycin; Transduction, Genetic

1971
Enzymatic acetylation of aminoglycoside antibiotics by Escherichia coli carrying an R factor.
    Biochemistry, 1971, May-11, Volume: 10, Issue:10

    Topics: Acetates; Acylation; Amino Sugars; Anti-Bacterial Agents; Carbon Isotopes; Cell-Free System; Chemical Phenomena; Chemistry; Coenzyme A; Coliphages; Color; Drug Resistance, Microbial; Electrophoresis; Escherichia coli; Gentamicins; Glycosides; Hexosamines; Hydrogen-Ion Concentration; Kanamycin; Methods; Neomycin; Paromomycin; Peptides; RNA, Viral; Species Specificity; Spectrophotometry

1971
Susceptibility of gram-negative anaerobic bacilli to gentamicin and other aminoglycosides.
    The Journal of infectious diseases, 1971, Volume: 124 Suppl

    Topics: Anaerobiosis; Bacillus; Bacteroides; Dosage Forms; Framycetin; Fusobacterium; Gentamicins; Indicator Dilution Techniques; Kanamycin; Neomycin; Oxygen; Paromomycin

1971
Drug dependence and phenotype masking in streptomycin dependent and paromomycin dependent mutants of Escherichia coli.
    Microbios, 1971, Volume: 4, Issue:14

    Topics: Agar; Anti-Bacterial Agents; Bacteriological Techniques; Cell Survival; Culture Media; Drug Resistance, Microbial; Escherichia coli; Ethanol; Genetics, Microbial; Kanamycin; Magnesium; Mutation; Neomycin; Paromomycin; Phenotype; Streptomycin

1971
Tuberculostatic effect of gentamicin in vitro.
    Journal of hygiene, epidemiology, microbiology, and immunology, 1967, Volume: 11, Issue:4

    Topics: Gentamicins; In Vitro Techniques; Kanamycin; Mycobacterium tuberculosis; Neomycin; Paromomycin; Streptomycin

1967
Drug dependence and phenotypic masking in Gram positive and Gram negative bacteria.
    Microbios, 1971, Volume: 4, Issue:13

    Topics: Bacillus cereus; Bacteria; Drug Resistance, Microbial; Escherichia coli; Genes; Kanamycin; Microbial Sensitivity Tests; Mutation; Neomycin; Paromomycin; Phenotype; Proteus; Staphylococcus; Streptomycin

1971
Effect of neomycin and kanamycin upon intestinal absortion.
    Annals of the New York Academy of Sciences, 1966, Jun-14, Volume: 132, Issue:2

    Topics: Bile; Bile Acids and Salts; Bilirubin; Chromatography, Thin Layer; Fats; Feces; Humans; Intestinal Absorption; Kanamycin; Malabsorption Syndromes; Neomycin; Paromomycin

1966
Distribution of R factors among Shigella strains isolated in Japan.
    Japanese journal of microbiology, 1969, Volume: 13, Issue:2

    Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Colistin; Furazolidone; Gentamicins; Japan; Kanamycin; Nalidixic Acid; Neomycin; Paromomycin; Penicillin Resistance; Serotyping; Shigella; Streptomycin; Sulfanilamides; Tetracycline

1969
Treatment of sonne dysentery.
    British medical journal, 1965, Oct-16, Volume: 2, Issue:5467

    Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chloramphenicol; Dysentery, Bacillary; Furazolidone; Humans; Infant; Infant, Newborn; Nalidixic Acid; Neomycin; Oxytetracycline; Paromomycin; Shigella sonnei; Statistics as Topic; Streptomycin; Sulfonamides; Tetracycline

1965
Dwarf-colony variants of Staphylococcus aureus resistant to aminoglucoside antibiotics and to a fatty acid.
    Journal of medical microbiology, 1969, Volume: 2, Issue:3

    Topics: Acetates; Anti-Bacterial Agents; Aspartic Acid; Culture Media; Drug Resistance, Microbial; Framycetin; Fructose; Gentamicins; Glycosides; Humans; Kanamycin; Linoleic Acids; Microbial Sensitivity Tests; Neomycin; Oxaloacetates; Oxidation-Reduction; Paromomycin; Pyruvates; Skin; Staphylococcus; Streptomycin

1969
[The position of gentamicin in the group of basic oligosaccharide antibiotics].
    Casopis lekaru ceskych, 1970, Apr-17, Volume: 109, Issue:17

    Topics: Anti-Bacterial Agents; Bacteria; Gentamicins; Kanamycin; Neomycin; Paromomycin; Streptomycin

1970
Comparison of bacteriostatic and bacteriocidal effects of gentamicin and various other antibiotics on the Proteus group of microorganisms.
    Casopis lekaru ceskych, 1970, Apr-17, Volume: 109, Issue:17

    Topics: Anti-Bacterial Agents; Gentamicins; Kanamycin; Neomycin; Paromomycin; Proteus; Streptomycin

1970
Deafness complicating antibiotic therapy of hepatic encephalopathy.
    Annals of internal medicine, 1970, Volume: 73, Issue:3

    Topics: Adult; Aged; Alcoholism; Ascites; Audiometry; Creatinine; Deafness; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Neomycin; Paromomycin; Time Factors

1970
Neomycins D, E and F: identity with paromamine, paromomycin I and paromomycin II.
    The Journal of antibiotics, 1970, Volume: 23, Issue:9

    Topics: Chromatography, Ion Exchange; Magnetic Resonance Spectroscopy; Neomycin; Paromomycin; Spectrum Analysis

1970
[Effect of 4 antibiotics of the oligosaccharide group on Taenia saginata].
    Lyon medical, 1971, Jan-24, Volume: 225, Issue:2

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Female; Humans; Kanamycin; Male; Middle Aged; Neomycin; Oligosaccharides; Paromomycin; Streptomycin; Taeniasis

1971
Separation of aminoglycosidic antibiotics by gas-liquid chromatography.
    The Journal of antibiotics, 1971, Volume: 24, Issue:7

    Topics: Anti-Bacterial Agents; Chromatography, Gas; Glycosides; Kanamycin; Neomycin; Paromomycin

1971
Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics. The effect of drug concentration.
    The Journal of biological chemistry, 1968, Jun-25, Volume: 243, Issue:12

    Topics: Anti-Bacterial Agents; Binding Sites; Carbon Isotopes; Eukaryota; Genetic Code; Gentamicins; Glycosides; Kanamycin; Mutation; Neomycin; Paromomycin; RNA; Streptomycin

1968
Aminoglycosides. (Streptomycin and the neomycin group).
    British medical journal, 1968, Aug-03, Volume: 3, Issue:5613

    Topics: Drug Resistance, Microbial; Framycetin; Gentamicins; Humans; Kanamycin; Neomycin; Paromomycin; Streptomycin; Tuberculosis

1968
The effect of antibiotics of the neomycin group on experimental cutaneous leishmaniasis.
    Annals of tropical medicine and parasitology, 1968, Volume: 62, Issue:1

    Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Framycetin; Kanamycin; Leishmaniasis; Mice; Neomycin; Paromomycin

1968
Faecal flora changes after oral antibiotics.
    Proceedings of the Royal Society of Medicine, 1969, Mar-03, Volume: 62, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Feces; Humans; Neomycin; Oxytetracycline; Paromomycin

1969
[On some mono N-alkyl derivatives of neomycin and paromomycin].
    Bulletin de la Societe chimique de France, 1969, Volume: 7

    Topics: Chemical Phenomena; Chemistry; Neomycin; Paromomycin

1969
[Evaluation in vitro of the antibacterial activity of some antibiotics and chemotherapeutic agents on germs in sputum. 3. The antibiotics of the streptomycin group].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Sep-30, Volume: 41, Issue:18

    Topics: Bronchial Diseases; Drug Resistance, Microbial; Humans; Kanamycin; Neomycin; Paromomycin; Sputum; Streptomycin

1965
Interaction of streptothricin and related antibiotics with nucleic acids.
    Biochimica et biophysica acta, 1967, Volume: 145, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cattle; Centrifugation, Zonal; Chemical Phenomena; Chemical Precipitation; Chemistry, Physical; Densitometry; DNA; DNA, Bacterial; Kanamycin; Macromolecular Substances; Neomycin; Nucleic Acid Denaturation; Paromomycin; Proteus; Spectrophotometry; Streptomyces; Streptomycin; Thymus Gland

1967
Antibiotics in the chemotherapy of amebiasis.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1984, Volume: 3, Issue:6

    Topics: Amebiasis; Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Erythromycin; Gentamicins; Humans; Neomycin; Novobiocin; Paromomycin; Penicillins; Polymyxins; Rifamycins; Streptomycin; Tetracyclines

1984
Aminoglycoside antibiotics. XV Chemical conversion of neomycin B to paromomycin I, 6"'-deamino-6"'-hydroxyneomycin B and 6"'-deamino-6"'-hydroxy-paromomycin I.
    The Journal of antibiotics, 1983, Volume: 36, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Framycetin; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Paromomycin

1983
Neomycin biosynthesis: the involvement of neamine and paromamine as intermediates.
    The Journal of antibiotics, 1984, Volume: 37, Issue:1

    Topics: Aminoglycosides; Chemical Phenomena; Chemistry; Neomycin; Paromomycin; Streptomyces

1984
[Acute liver failure--therapeutic aspects 1982].
    Fortschritte der Medizin, 1982, Jul-22, Volume: 100, Issue:27-28

    Topics: Acute Disease; Animals; Antithrombins; Blood Coagulation Factors; Cimetidine; Dietary Carbohydrates; Enema; Exchange Transfusion, Whole Blood; Gastrointestinal Hemorrhage; Glucose; Humans; Lactulose; Liver Diseases; Neomycin; Papio; Paromomycin; Peptic Ulcer; Plasma Exchange

1982
[Comparative study of serum levels and urinary excretion following oral administration of paromomycin and neomycin (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:11

    Topics: Adult; Humans; Intestinal Absorption; Liver Cirrhosis; Male; Neomycin; Paromomycin; Portacaval Shunt, Surgical

1981
6"'-Deamino-6"'-hydroxy derivatives, as intermediates in the biosynthesis of neomycin and paromomycin.
    The Journal of antibiotics, 1981, Volume: 34, Issue:5

    Topics: Chemical Phenomena; Chemistry, Physical; Fermentation; Hydrolysis; Microbial Sensitivity Tests; Molecular Conformation; Mutation; Neomycin; Paromomycin; Streptomyces

1981
[Faecal bacterial flora in cirrhotic patients and effects of administration of antibiotics or lactulose (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1980, Volume: 77, Issue:10

    Topics: Anti-Bacterial Agents; Bacteria; Disaccharides; Feces; Humans; Lactulose; Liver Cirrhosis; Minocycline; Neomycin; Paromomycin

1980
Ribosomes of Leishmania are a target for the aminoglycosides.
    Parasitology research, 1995, Volume: 81, Issue:5

    Topics: Animals; Centrifugation, Density Gradient; Cytoplasm; Framycetin; Leishmania donovani; Leishmania tropica; Magnesium; Mitochondria; Paromomycin; Pentamidine; Ribosomes; Spermidine

1995
Aminoglycoside resistance in Haemophilus influenzae.
    Journal of chemotherapy (Florence, Italy), 1995, Volume: 7, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Microbial; Drug Resistance, Multiple; Haemophilus influenzae; Kanamycin; Neomycin; Paromomycin; Phosphotransferases (Alcohol Group Acceptor); Streptomycin

1995
Neomycin inhibition of the hammerhead ribozyme involves ionic interactions.
    Biochemistry, 1995, Sep-05, Volume: 34, Issue:35

    Topics: Base Sequence; Binding, Competitive; Carbohydrate Sequence; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Magnesium; Molecular Sequence Data; Molecular Structure; Neomycin; Nucleic Acid Conformation; Paromomycin; Ribostamycin; RNA, Catalytic; Thermodynamics

1995
Enteral and parenteral anti-endotoxin treatment in experimental colitis.
    Hepato-gastroenterology, 1994, Volume: 41, Issue:6

    Topics: Animals; Anti-Infective Agents, Local; Antitoxins; Body Weight; Cefuroxime; Colitis; Endotoxins; Enteral Nutrition; Injections, Intravenous; Male; Metronidazole; Neomycin; Organ Size; Parenteral Nutrition; Paromomycin; Polymyxins; Rats; Rats, Wistar; Taurine; Thiadiazines

1994
Biochemical alterations in paromomycin-treated Leishmania donovani promastigotes.
    Parasitology research, 1997, Volume: 83, Issue:2

    Topics: Amebicides; Animals; Chloramphenicol; Cycloheximide; Cytoplasm; DNA, Protozoan; Humans; Leishmania donovani; Leucine; Membrane Fluidity; Mitochondria; Neomycin; Paromomycin; Protozoan Proteins; RNA, Protozoan; Thymidine; Time Factors; Uridine

1997
In vivo interference of paromomycin with mitochondrial activity of Leishmania.
    Experimental cell research, 1997, May-01, Volume: 232, Issue:2

    Topics: Animals; Antiprotozoal Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Energy Metabolism; Kinetics; Leishmania donovani; Mitochondria; NAD; Neomycin; Oxidoreductases; Oxygen Consumption; Paromomycin; Protozoan Proteins; Succinates; Succinic Acid; Uncoupling Agents; Valinomycin

1997
Structure-based discovery of ligands targeted to the RNA double helix.
    Biochemistry, 1997, Sep-23, Volume: 36, Issue:38

    Topics: Aminoglycosides; Anti-Bacterial Agents; Circular Dichroism; Computer Simulation; Kanamycin; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Neomycin; Nucleic Acid Conformation; Nucleic Acid Denaturation; Paromomycin; Poly A-U; RNA, Double-Stranded; Software; Titrimetry

1997
A novel RNA motif for neomycin recognition.
    Chemistry & biology, 1995, Volume: 2, Issue:8

    Topics: Anti-Bacterial Agents; Autoradiography; Base Sequence; Binding Sites; Chromatography, Affinity; Cloning, Molecular; DNA Footprinting; Hydrolysis; Magnesium; Molecular Sequence Data; Neomycin; Paromomycin; RNA; Sequence Homology, Nucleic Acid

1995
Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA.
    Chemistry & biology, 1998, Volume: 5, Issue:7

    Topics: Anti-Bacterial Agents; Hydrogen-Ion Concentration; Kanamycin; Methylation; Neomycin; Osmolar Concentration; Paromomycin; RNA, Bacterial; RNA, Ribosomal, 16S

1998
Inhibition of RNase P RNA cleavage by aminoglycosides.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, May-25, Volume: 96, Issue:11

    Topics: Anti-Bacterial Agents; Base Sequence; Binding, Competitive; Endoribonucleases; Escherichia coli; Escherichia coli Proteins; Framycetin; Kanamycin; Kinetics; Lead; Magnesium; Models, Molecular; Molecular Sequence Data; Mycoplasma; Nucleic Acid Conformation; Paromomycin; Recombinant Proteins; Ribonuclease P; RNA; RNA, Catalytic; RNA, Ribosomal, 16S; Substrate Specificity; Transcription, Genetic

1999
Specificity in the binding of aminoglycosides to HIV-RRE RNA.
    Biochemistry, 1999, Jun-29, Volume: 38, Issue:26

    Topics: Anti-Bacterial Agents; Binding Sites; DNA Mutational Analysis; Fluorescent Dyes; Framycetin; Gene Products, rev; HIV; Paromomycin; Response Elements; rev Gene Products, Human Immunodeficiency Virus; Rhodamines; RNA, Viral

1999
The distribution of RNA motifs in natural sequences.
    Nucleic acids research, 1999, Nov-15, Volume: 27, Issue:22

    Topics: Adenosine Triphosphate; Base Sequence; Binding Sites; Catalytic Domain; Databases, Factual; Evolution, Molecular; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Gene Products, rev; Gene Products, tat; Information Storage and Retrieval; Ligands; Molecular Sequence Data; Neomycin; Nucleic Acid Conformation; Paromomycin; Phylogeny; Ribosomal Proteins; RNA; RNA-Binding Proteins; RNA, Catalytic; RNA, Transfer; Theophylline

1999
Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system.
    RNA (New York, N.Y.), 2000, Volume: 6, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Cinnamates; Codon, Terminator; Dose-Response Relationship, Drug; Escherichia coli; Genes, Reporter; Gentamicins; Humans; Hygromycin B; Kanamycin; Neomycin; Paromomycin; Plasmids; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Sisomicin; Streptomycin; Tobramycin

2000
Inhibition of eukaryotic ribonuclease P activity by aminoglycosides: kinetic studies.
    FEBS letters, 2000, Nov-17, Volume: 485, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Binding, Competitive; Cations; Dictyostelium; Endoribonucleases; Enzyme Inhibitors; Gentamicins; Kanamycin; Kinetics; Magnesium; Mathematics; Neomycin; Paromomycin; Ribonuclease P; RNA, Catalytic; Static Electricity; Tobramycin

2000
Structural origins of aminoglycoside specificity for prokaryotic ribosomes.
    Journal of molecular biology, 2001, Mar-09, Volume: 306, Issue:5

    Topics: Adenosine; Anti-Bacterial Agents; Drug Resistance, Microbial; Guanosine; Magnetic Resonance Spectroscopy; Molecular Structure; Neomycin; Paromomycin; RNA, Bacterial; RNA, Ribosomal, 16S; RNA, Transfer, Amino Acyl; Species Specificity; Structure-Activity Relationship; Substrate Specificity

2001
Direct observation of aminoglycoside-RNA interactions by surface plasmon resonance.
    Journal of the American Chemical Society, 1997, Apr-23, Volume: 119, Issue:16

    Topics: Anti-Bacterial Agents; Antibody Affinity; Base Sequence; Binding Sites; Biotinylation; Chemistry, Pharmaceutical; Framycetin; Gene Products, rev; Genes, env; HIV-1; Paromomycin; Protein Binding; rev Gene Products, Human Immunodeficiency Virus; RNA, Messenger; RNA, Viral; Structure-Activity Relationship

1997
Aminoglycoside binding to human and bacterial A-Site rRNA decoding region constructs.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:10

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Fluorescence Polarization; Framycetin; Humans; Kanamycin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Paromomycin; Rhodamines; RNA, Ribosomal; RNA, Ribosomal, 16S; RNA, Ribosomal, 18S; Structure-Activity Relationship; Tobramycin

2001
A Streptomyces rimosus aphVIII gene coding for a new type phosphotransferase provides stable antibiotic resistance to Chlamydomonas reinhardtii.
    Gene, 2001, Oct-17, Volume: 277, Issue:1-2

    Topics: 5' Untranslated Regions; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Chlamydomonas reinhardtii; DNA, Bacterial; Drug Resistance; Gene Expression Regulation, Enzymologic; HSP70 Heat-Shock Proteins; Kanamycin; Kanamycin Kinase; Molecular Sequence Data; Neomycin; Paromomycin; Plasmids; Promoter Regions, Genetic; Ribulose-Bisphosphate Carboxylase; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Streptomyces; Transformation, Genetic

2001
Binding of aminoglycoside antibiotics to the small ribosomal subunit: a continuum electrostatics investigation.
    Journal of the American Chemical Society, 2002, Feb-20, Volume: 124, Issue:7

    Topics: Anti-Bacterial Agents; Binding Sites; Kinetics; Models, Molecular; Neomycin; Paromomycin; Ribostamycin; RNA, Ribosomal, 16S; Static Electricity; Thermodynamics

2002
30S ribosomal subunit assembly is a target for inhibition by aminoglycosides in Escherichia coli.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:5

    Topics: Anti-Bacterial Agents; Escherichia coli; Inhibitory Concentration 50; Neomycin; Paromomycin; Ribosomal Proteins; RNA, Ribosomal

2002
Thermodynamics of aminoglycoside-rRNA recognition: the binding of neomycin-class aminoglycosides to the A site of 16S rRNA.
    Biochemistry, 2002, Jun-18, Volume: 41, Issue:24

    Topics: Anti-Bacterial Agents; Binding Sites; Calorimetry, Differential Scanning; Hot Temperature; Hydrogen-Ion Concentration; Neomycin; Nucleic Acid Heteroduplexes; Oligonucleotides; Paromomycin; Protons; Quaternary Ammonium Compounds; Ribostamycin; RNA, Ribosomal, 16S; Salts; Sodium; Static Electricity; Thermodynamics

2002
[Recurrent episodes of acidosis with encephalopathy in a hemodialysis program patient with short bowel syndrome].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:2

    Topics: Acidosis, Lactic; Adult; Bicarbonates; Brain Diseases, Metabolic; Consciousness Disorders; Drug Therapy, Combination; Dysarthria; Gram-Positive Bacteria; Humans; Intestines; Kidney Failure, Chronic; Lactates; Male; Neomycin; Oxalates; Paromomycin; Recurrence; Renal Dialysis; Short Bowel Syndrome; Urinary Calculi

2002
Stereospecificity of aminoglycoside-ribosomal interactions.
    Biochemistry, 2002, Aug-20, Volume: 41, Issue:33

    Topics: Anti-Bacterial Agents; Binding, Competitive; Fluorescence Polarization; Framycetin; Inhibitory Concentration 50; Microbial Sensitivity Tests; Oligoribonucleotides; Paromomycin; Protein Biosynthesis; Rhodamines; Ribosomes; RNA, Bacterial; RNA, Fungal; RNA, Ribosomal; Spectrometry, Fluorescence; Stereoisomerism; Tobramycin

2002
HIV-1 RNA dimerization initiation site is structurally similar to the ribosomal A site and binds aminoglycoside antibiotics.
    The Journal of biological chemistry, 2003, Jan-24, Volume: 278, Issue:4

    Topics: Anti-Bacterial Agents; Binding Sites; Dimerization; HIV-1; Models, Molecular; Neomycin; Nucleic Acid Conformation; Paromomycin; Protein Binding; Ribosomes; RNA; RNA, Viral; Temperature; Ultraviolet Rays

2003
Coupling of drug protonation to the specific binding of aminoglycosides to the A site of 16 S rRNA: elucidation of the number of drug amino groups involved and their identities.
    Journal of molecular biology, 2003, Mar-07, Volume: 326, Issue:5

    Topics: Anti-Bacterial Agents; Binding Sites; Calorimetry, Differential Scanning; Carbohydrate Sequence; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Neomycin; Paromomycin; Protons; RNA, Ribosomal, 16S

2003
Selective enumeration of Lactobacillus delbrueckii ssp. bulgaricus, Streptococcus thermophilus, Lactobacillus acidophilus, bifidobacteria, Lactobacillus casei, Lactobacillus rhamnosus, and propionibacteria.
    Journal of dairy science, 2003, Volume: 86, Issue:7

    Topics: Agar; Bifidobacterium; Colony Count, Microbial; Culture Media; Dairy Products; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Lactobacillus; Lactobacillus acidophilus; Lithium Chloride; Nalidixic Acid; Neomycin; Oxygen; Paromomycin; Probiotics; Propionibacterium; Streptococcus; Yogurt

2003
Susceptibility and cross resistance of bacteria to streptomycin, neomycin, paromomycin, and kanamycin.
    Annals of the New York Academy of Sciences, 1958, Sep-30, Volume: 76, Issue:2

    Topics: Anti-Bacterial Agents; Bacteria; Humans; Kanamycin; Neomycin; Paromomycin; Streptomycin

1958
Susceptibility and crossresistance of bacteria to four related antibiotics: kanamycin, paromomycin, neomycin and streptomycin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 99, Issue:2

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacteria; Humans; Kanamycin; Neomycin; Paromomycin; Streptomycin

1958
Enterocolitis due to phage type 54 staphylococci resistant to kanamycin, neomycin, paromomycin and chloramphenicol.
    The New England journal of medicine, 1960, Dec-01, Volume: 263

    Topics: Anti-Bacterial Agents; Chloramphenicol; Colitis; Enterocolitis; Kanamycin; Neomycin; Paromomycin; Staphylococcal Infections; Staphylococcus; Staphylococcus Phages

1960
Excretion of antibiotics in bile.
    British journal of pharmacology and chemotherapy, 1961, Volume: 17

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bile; Biological Transport; Body Fluids; Chloramphenicol; Neomycin; Paromomycin; Penicillanic Acid; Penicillin G; Penicillins; Rats; Streptomycin

1961
The pattern of cross-sensitivity to neomycin. 51 cases of secondary sensitization to paromomvcin (Humatin).
    Dermatologica, 1962, Volume: 125

    Topics: Drug Hypersensitivity; Humans; Neomycin; Paromomycin

1962
[A "salve contest" with corticosteroid ointments. Pros and cons of the frequently added neomycin e.d].
    Geneeskundige gids, 1963, Apr-04, Volume: 41

    Topics: Adrenal Cortex Hormones; Dexamethasone; Eczema; Hydrocortisone; Neomycin; Ointments; Paromomycin

1963
Kanamycin, neomycin and paromomycin.
    Pediatric clinics of North America, 1961, Volume: 8

    Topics: Anti-Bacterial Agents; Humans; Kanamycin; Neomycin; Paromomycin

1961
[Pharmacology of new basic oligosaccharide antibiotics].
    Antibiotica et chemotherapia. Fortschritte. Advances. Progres, 1963, Volume: 11

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Humans; Kanamycin; Neomycin; Oligosaccharides; Paromomycin

1963
[RAPID DETERMINATION OF THE SENSITIVITY OF BACTERIA TO ANTIBIOTICS].
    Ceskoslovenska epidemiologie, mikrobiologie, imunologie, 1963, Volume: 12

    Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Colistin; Drug Resistance; Drug Resistance, Microbial; Erythromycin; Escherichia coli; Kanamycin; Methicillin; Neomycin; Oleandomycin; Oxacillin; Paromomycin; Penicillin G; Polymyxins; Research; Rifamycins; Staphylococcus; Streptomycin; Tetracycline; Tetrazolium Salts; Vancomycin

1963
REPLACEMENT COLIFORM FLORA IN CARRIERS OF INTESTINAL PATHOGENS.
    The Journal of hygiene, 1964, Volume: 62

    Topics: Adolescent; Bacillus; Candidiasis; Carrier State; Child; Drug Resistance; Drug Resistance, Microbial; Dysentery; Dysentery, Bacillary; Escherichia coli; Humans; Infant; Infant, Newborn; Intestines; Neomycin; Paromomycin; Salmonella; Salmonella paratyphi A; Salmonella typhi; Salmonella typhimurium; Shigella; Streptomycin

1964
SEPARATION AND QUANTITATIVE DETERMINATION OF AMINO SUGAR ANTIBIOTICS AND THEIR DEGRADATION PRODUCTS BY MEANS OF AN IMPROVED METHOD OF CHROMATOGRAPHY ON RESIN.
    Journal of chromatography, 1964, Volume: 13

    Topics: Amino Sugars; Anti-Bacterial Agents; Antibiotics, Antitubercular; Chromatography; Ion Exchange Resins; Kanamycin; Neomycin; Paromomycin; Research; Resins, Plant

1964
REDUCTION OF SERUM CHOLESTEROL CONCENTRATIONS BY PAROMOMYCIN IN PATIENTS WITH ARTERIOSCLEROSIS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Arteriosclerosis; Child; Cholesterol; Drug Therapy; Humans; Kanamycin; Neomycin; Paromomycin

1964
[PAPER AND THIN-LAYER CHROMATOGRAPHY OF WATER-SOLUBLE BASIC ANTIBIOTICS PRODUCED BY STREPTOMYCES].
    The Journal of antibiotics. Ser. B, 1964, Volume: 17

    Topics: Ammonium Chloride; Anti-Bacterial Agents; Antibiotics, Antitubercular; Carbon; Chromatography; Chromatography, Thin Layer; Kanamycin; Neomycin; Paromomycin; Research; Streptomyces; Streptomycin; Viomycin; Water

1964
STREPTOMYCINOID ANTIBIOTICS: SYNERGISM BY PUROMYCIN.
    Science (New York, N.Y.), 1964, Nov-06, Volume: 146, Issue:3645

    Topics: Anti-Bacterial Agents; Chloramphenicol; Escherichia coli; Kanamycin; Neomycin; Paromomycin; Pharmacology; Puromycin; Research; Ribosomes; Streptomycin; Viomycin

1964
IATROGENIC STAPHYLOCOCCAL ENTEROCOLITIS.
    Annals of surgery, 1964, Volume: 160

    Topics: Anti-Bacterial Agents; Bacteriophage Typing; Chloramphenicol; Drug Therapy; Enterocolitis; Humans; Iatrogenic Disease; Neomycin; Paromomycin; Penicillins; Postoperative Complications; Preoperative Care; Staphylococcal Infections; Sulfonamides; Surgical Wound Infection; Tetracycline

1964
REGENERATION OF ANTIBIOTIC ACTIVITY BY DEACETYLATION OF N-ACETYL DERIVATIVES OF DEOXYSTREPTAMINE-CONTAINING ANTIBIOTICS.
    Journal of medicinal chemistry, 1964, Volume: 7

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacillus subtilis; Chemistry, Pharmaceutical; Gentamicins; Kanamycin; Neomycin; Paromomycin; Pharmacology; Regeneration; Research; Staphylococcus

1964
AN EXTENSIVE OUTBREAK OF GASTROENTERITIS CAUSED BY SALMONELLA NEWPORT. II. SOME CLINICAL OBSERVATIONS ON 488 HOSPITALIZED CASES AND THE RESULTS OF CULTURES.
    Acta medica Scandinavica, 1965, Volume: 177

    Topics: Anti-Bacterial Agents; Chloramphenicol; Disease Outbreaks; Drug Therapy; Gastroenteritis; Humans; Neomycin; Nitrofurans; Paromomycin; Salmonella; Salmonella Food Poisoning; Statistics as Topic; Sweden; Toxicology

1965
[ON THE CONFORMATION OF THE ANTIBIOTICS PAROMOMYCIN AND NEOMYCIN B].
    Die Pharmazie, 1964, Volume: 19

    Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Dermatologic Agents; Framycetin; Molecular Conformation; Neomycin; Paromomycin; Pharmacy; Research

1964
Neomycin and paromomycin inhibit 30S ribosomal subunit assembly in Staphylococcus aureus.
    Current microbiology, 2003, Volume: 47, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Centrifugation, Density Gradient; Colony Count, Microbial; Neomycin; Paromomycin; Protein Biosynthesis; Protein Synthesis Inhibitors; Ribosomes; Staphylococcus aureus

2003
Structure-activity relationship of neomycin, paromomycin, and neamine-arginine conjugates, targeting HIV-1 gp120-CXCR4 binding step.
    Antiviral research, 2003, Volume: 60, Issue:3

    Topics: Anti-HIV Agents; Antibodies, Monoclonal; Arginine; Cell Line; Cells, Cultured; Chemokine CCL5; Chemokine CXCL12; Chemokines, CXC; Drug Resistance, Viral; Framycetin; HIV Envelope Protein gp120; HIV-1; Humans; Leukocytes, Mononuclear; Neomycin; Paromomycin; Receptors, CXCR4; Structure-Activity Relationship; Virus Replication

2003
Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication.
    Biochemistry, 2004, Aug-03, Volume: 43, Issue:30

    Topics: Aminoglycosides; Binding, Competitive; Circular Dichroism; DNA, Viral; Drug Delivery Systems; Enzyme Activation; HIV Reverse Transcriptase; HIV-1; Humans; Hydrolysis; Neomycin; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Paromomycin; Reverse Transcriptase Inhibitors; Ribonuclease H; Ribostamycin; RNA, Viral; Thermodynamics; Virus Replication

2004
A minimum structure of aminoglycosides that causes an initiation shift of trans-translation.
    Nucleic acids research, 2004, Volume: 32, Issue:14

    Topics: Aminoglycosides; Frameshifting, Ribosomal; Framycetin; Hygromycin B; Mutation; Paromomycin; Protein Biosynthesis; RNA, Bacterial; Streptomycin

2004
Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy.
    FEBS letters, 2004, Nov-19, Volume: 577, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Arginine; Binding Sites; Fluorescence Polarization; HIV-1; Molecular Structure; Neomycin; Nuclear Magnetic Resonance, Biomolecular; Paromomycin; RNA, Viral; Structure-Activity Relationship

2004
Conformational constraint as a means for understanding RNA-aminoglycoside specificity.
    Journal of the American Chemical Society, 2005, Jul-13, Volume: 127, Issue:27

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Carbohydrate Sequence; Drug Design; Endoribonucleases; HIV Long Terminal Repeat; HIV-1; Ligands; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Neomycin; Paromomycin; Protein Structure, Tertiary; RNA; Sensitivity and Specificity; Spectrum Analysis; Structure-Activity Relationship

2005
Activity of some aminoglycoside antibiotics against true fungi, Phytophthora and Pythium species.
    Journal of applied microbiology, 2005, Volume: 99, Issue:4

    Topics: Antifungal Agents; Capsicum; Culture Media; Fungi; Neomycin; Paromomycin; Phytophthora; Plant Diseases; Pythium; Ribostamycin; Solanum lycopersicum; Streptomycin

2005
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
    Nucleic acids research, 2005, Volume: 33, Issue:17

    Topics: Adenine; Aminoglycosides; Anti-Bacterial Agents; Anticodon; Base Sequence; Binding Sites; Codon; Crystallography, X-Ray; Framycetin; Gentamicins; Kanamycin; Models, Molecular; Oligoribonucleotides; Paromomycin; Ribosomes; Ribostamycin; RNA, Ribosomal, 16S

2005
Quantitative analysis of shape-specific interactions of Rev response element with a positively charged Rev peptide by capillary electrophoresis.
    Electrophoresis, 2005, Volume: 26, Issue:22

    Topics: Amino Acid Sequence; Base Sequence; Binding, Competitive; Buffers; Electrophoresis, Capillary; Framycetin; Gene Products, rev; Genes, env; Inhibitory Concentration 50; Paromomycin; Peptide Fragments; Sensitivity and Specificity

2005
Inhibition of human tyrosyl-DNA phosphodiesterase by aminoglycoside antibiotics and ribosome inhibitors.
    Molecular pharmacology, 2006, Volume: 70, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; DNA Repair; DNA, Recombinant; DNA, Single-Stranded; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Neomycin; Nucleic Acid Heteroduplexes; Oligonucleotides; Paromomycin; Phosphoric Diester Hydrolases; Substrate Specificity; Time Factors

2006
Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discovery.
    Journal of the American Chemical Society, 2007, Mar-21, Volume: 129, Issue:11

    Topics: Base Sequence; Dimerization; Fluorescent Dyes; HIV-1; Ligands; Molecular Sequence Data; Neomycin; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Paromomycin; RNA, Viral; Spectrometry, Fluorescence; Transcription Initiation Site

2007
Monitoring aminoglycoside-induced conformational changes in 16S rRNA through acrylamide quenching.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: 2-Aminopurine; Acrylamide; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Binding Sites; Fluorescence; Framycetin; Nucleic Acid Conformation; Paromomycin; RNA, Ribosomal, 16S; Spectrometry, Mass, Electrospray Ionization

2007
Inhibition of poly(A) polymerase by aminoglycosides.
    Biochimie, 2007, Volume: 89, Issue:10

    Topics: Adenosine Triphosphate; Aminoglycosides; Anti-Bacterial Agents; Catalysis; Dose-Response Relationship, Drug; Framycetin; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Paromomycin; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

2007
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
    Nature structural & molecular biology, 2007, Volume: 14, Issue:8

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Crystallography, X-Ray; Escherichia coli; Gentamicins; Models, Molecular; Molecular Structure; Neomycin; Paromomycin; Protein Subunits; Ribosomal Proteins; Ribosomes; Structure-Activity Relationship

2007
In vivo translational inaccuracy in Escherichia coli: missense reporting using extremely low activity mutants of Vibrio harveyi luciferase.
    Biochemistry, 2007, Dec-04, Volume: 46, Issue:48

    Topics: Codon; Escherichia coli; Histidine; Leucine; Luciferases; Mutation, Missense; Neomycin; Paromomycin; Protein Biosynthesis; Streptomycin; Vibrio

2007
Characterization of a 30S ribosomal subunit assembly intermediate found in Escherichia coli cells growing with neomycin or paromomycin.
    Archives of microbiology, 2008, Volume: 189, Issue:5

    Topics: Anti-Bacterial Agents; Blotting, Northern; Escherichia coli; Escherichia coli Proteins; Neomycin; Paromomycin; Ribosomal Proteins; Ribosome Subunits, Small, Bacterial; RNA, Bacterial; RNA, Ribosomal, 16S

2008
Aminoglycoside binding to Oxytricha nova telomeric DNA.
    Biochemistry, 2010, Nov-16, Volume: 49, Issue:45

    Topics: Aminoglycosides; Animals; Base Sequence; Calorimetry; DNA, Protozoan; Framycetin; Guanine; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Neomycin; Oxytricha; Paromomycin; Ribostamycin; Spectrophotometry, Ultraviolet

2010
Cooperative, heparan sulfate-dependent cellular uptake of dimeric guanidinoglycosides.
    Chembiochem : a European journal of chemical biology, 2010, Nov-02, Volume: 11, Issue:16

    Topics: Animals; Biological Transport; CHO Cells; Cricetinae; Cricetulus; Dimerization; Flow Cytometry; Glycosides; Guanidine; Heparitin Sulfate; Neomycin; Paromomycin; Tobramycin

2010
Influence of charge and structure on the coordination chemistry of copper aminoglycosides.
    Dalton transactions (Cambridge, England : 2003), 2011, Feb-28, Volume: 40, Issue:8

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Copper; Framycetin; Kanamycin; Magnetic Resonance Spectroscopy; Molecular Structure; Paromomycin; Spectrophotometry, Ultraviolet; Static Electricity; Tobramycin

2011
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin.
    Journal of applied microbiology, 2011, Volume: 111, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Molecular Structure; Neomycin; Oxidoreductases; Paromomycin; Streptomyces; Substrate Specificity; Transaminases

2011
Thermodynamics of nucleic acid "shape readout" by an aminosugar.
    Biochemistry, 2011, Oct-25, Volume: 50, Issue:42

    Topics: Aminoglycosides; Animals; Binding, Competitive; Cattle; DNA; DNA, A-Form; DNA, B-Form; Fluoresceins; Neomycin; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Nucleic Acids; Paromomycin; Polynucleotides; Ribostamycin; Thermodynamics

2011
Antibiotic selection by the promiscuous aminoglycoside acetyltransferase-(3)-IIIb is thermodynamically achieved through the control of solvent rearrangement.
    Biochemistry, 2011, Nov-01, Volume: 50, Issue:43

    Topics: Acetyltransferases; Anti-Bacterial Agents; Binding Sites; Calorimetry; Coenzyme A; Escherichia coli; Models, Molecular; Neomycin; Nuclear Magnetic Resonance, Biomolecular; Paromomycin; Solvents; Substrate Specificity; Thermodynamics

2011
Hybrid aminoglycoside antibiotics via Tsuji palladium-catalyzed allylic deoxygenation.
    Organic letters, 2011, Dec-16, Volume: 13, Issue:24

    Topics: Aminoglycosides; Anti-Bacterial Agents; Catalysis; Neomycin; Oxidation-Reduction; Palladium; Paromomycin; Sisomicin

2011
Paromomycin and neomycin B derived cationic lipids: synthesis and transfection studies.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Mar-28, Volume: 158, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cholesterol; Female; Framycetin; Genes, Reporter; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Oleic Acids; Paromomycin; Transfection

2012
Investigation of RNA-ligand interactions by 19F NMR spectroscopy using fluorinated probes.
    Angewandte Chemie (International ed. in English), 2012, Sep-17, Volume: 51, Issue:38

    Topics: Aminoglycosides; Fluorescent Dyes; Fluorine; Framycetin; Ligands; Magnetic Resonance Spectroscopy; Neomycin; Paromomycin; RNA

2012
Protein dynamics are influenced by the order of ligand binding to an antibiotic resistance enzyme.
    Biochemistry, 2014, Jan-14, Volume: 53, Issue:1

    Topics: Acetyltransferases; Aminoglycosides; Coenzyme A; Ligands; Light; Neomycin; Nuclear Magnetic Resonance, Biomolecular; Paromomycin; Protein Binding; Protein Conformation; Scattering, Radiation; Thermodynamics

2014
Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
    Nature communications, 2015, Jul-30, Volume: 6

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Escherichia coli; Escherichia coli Proteins; Framycetin; Neomycin; Paromomycin; Ribosome Subunits, Large, Bacterial; Ribosome Subunits, Small, Bacterial; Ribosomes; Ribostamycin; RNA, Bacterial; Rotation

2015
Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics.
    Nucleic acids research, 2015, Sep-30, Volume: 43, Issue:17

    Topics: Animals; Antiprotozoal Agents; Binding Sites; Cell Line; Computer Simulation; Guinea Pigs; Humans; Leishmania; Macrophages; Male; Models, Molecular; Neomycin; Paromomycin; Protein Biosynthesis; Protein Synthesis Inhibitors; Ribosomes; RNA, Ribosomal

2015
Binding thermodynamics of paromomycin, neomycin, neomycin-dinucleotide and -diPNA conjugates to bacterial and human rRNA.
    Journal of molecular recognition : JMR, 2016, Volume: 29, Issue:4

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Calorimetry; Humans; Neomycin; Paromomycin; Protein Binding; RNA, Bacterial; RNA, Ribosomal; Thermodynamics

2016
N6', N6''', and O4' Modifications to Neomycin Affect Ribosomal Selectivity without Compromising Antibacterial Activity.
    ACS infectious diseases, 2017, 05-12, Volume: 3, Issue:5

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Base Pairing; Base Sequence; Carbohydrate Conformation; Enterobacter cloacae; Klebsiella pneumoniae; Microbial Sensitivity Tests; Neomycin; Paromomycin; Protein Biosynthesis; Ribosomes; Staphylococcus aureus; Structure-Activity Relationship; Subcellular Fractions

2017
Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues: Importance of the Configuration at the 6'-Position and Differences between the 6'-Amino and Hydroxy Series.
    Journal of the American Chemical Society, 2017, 10-18, Volume: 139, Issue:41

    Topics: Anti-Bacterial Agents; Nebramycin; Neomycin; Paromomycin; Ribosomes

2017
Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ ions.
    Nucleic acids research, 2018, 02-16, Volume: 46, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cations, Divalent; Codon; Escherichia coli; Genetic Code; Gentamicins; Kinetics; Magnesium; Neomycin; Paromomycin; Peptide Elongation Factor Tu; Protein Biosynthesis; Ribosomes; RNA, Ribosomal, 16S; RNA, Transfer, Amino Acyl; Subcellular Fractions

2018
Molecular mechanisms for dynamic regulation of N1 riboswitch by aminoglycosides.
    Nucleic acids research, 2018, 11-02, Volume: 46, Issue:19

    Topics: Aminoglycosides; Binding Sites; Molecular Conformation; Molecular Dynamics Simulation; Neomycin; Paromomycin; Ribostamycin; Riboswitch

2018
Next-level riboswitch development-implementation of Capture-SELEX facilitates identification of a new synthetic riboswitch.
    Nucleic acids research, 2019, 05-21, Volume: 47, Issue:9

    Topics: Aptamers, Nucleotide; Ligands; Neomycin; Nucleic Acid Conformation; Paromomycin; Riboswitch; RNA; SELEX Aptamer Technique; Small Molecule Libraries; Structure-Activity Relationship; Theophylline

2019
Modification at the 2'-Position of the 4,5-Series of 2-Deoxystreptamine Aminoglycoside Antibiotics To Resist Aminoglycoside Modifying Enzymes and Increase Ribosomal Target Selectivity.
    ACS infectious diseases, 2019, 10-11, Volume: 5, Issue:10

    Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria; Binding Sites; Drug Resistance, Multiple, Bacterial; Hexosamines; Humans; Microbial Sensitivity Tests; Neomycin; Paromomycin; Protein Biosynthesis; Ribosomes; Structure-Activity Relationship

2019
Synthesis of a Pseudodisaccharide Suitable for Synthesis of Ring I Modified 4,5-2-Deoxystreptamine Type Aminoglycoside Antibiotics.
    The Journal of organic chemistry, 2020, 06-05, Volume: 85, Issue:11

    Topics: Aminoglycosides; Anti-Bacterial Agents; Hexosamines; Neomycin; Paromomycin

2020
Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation.
    RNA (New York, N.Y.), 2021, Volume: 27, Issue:9

    Topics: Anti-Bacterial Agents; Biological Transport; Cinnamates; Escherichia coli; Hygromycin B; Kanamycin; Kinetics; Neomycin; Paromomycin; Peptide Elongation Factor G; Protein Biosynthesis; Ribosome Subunits; RNA, Messenger; RNA, Transfer; Spectinomycin; Streptomycin; Viomycin

2021
RNA Chemical Labeling with Site-Specific, Relative Quantification by Mass Spectrometry for the Structural Study of a Neomycin-Sensing Riboswitch Aptamer Domain.
    ChemPlusChem, 2022, Volume: 87, Issue:11

    Topics: Aminoglycosides; Anti-Bacterial Agents; Framycetin; Ligands; Mass Spectrometry; Neomycin; Oligonucleotides; Paromomycin; Ribostamycin; Riboswitch; RNA

2022
Resistome in Streptomyces rimosus - A Reservoir of Aminoglycoside Antibiotics Resistance Genes.
    Biochemistry. Biokhimiia, 2023, Volume: 88, Issue:6

    Topics: Aminoglycosides; Anti-Bacterial Agents; Escherichia coli; Neomycin; Paromomycin; Streptomyces rimosus

2023