framycetin has been researched along with neamine in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (15.91) | 18.7374 |
| 1990's | 1 (1.14) | 18.2507 |
| 2000's | 30 (34.09) | 29.6817 |
| 2010's | 42 (47.73) | 24.3611 |
| 2020's | 1 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Cedergren, R; Leclerc, F | 1 |
| Cashman, DJ; Kellogg, GE; Rife, JP | 1 |
| Constantinou-Kokotou, T; Karikas, G; Kokotos, G | 1 |
| Rando, RR; Ryu, DH; Tan, CH | 1 |
| Detering, C; Varani, G | 1 |
| Bailly, C; Boden, O; Décout, JL; Désiré, J; Göbel, M; Ludwig, V; Riguet, E | 1 |
| Cregar, L; Goldman, ME; Hemscheidt, T; Jiao, GS; Millis, SZ; Nagata, M; O'Malley, S; Simo, O; Tang, C | 1 |
| Baasov, T; Cherniavsky, M; Hainrichson, M; Nudelman, I; Shallom-Shezifi, D; Yaniv, O; Yaron, S | 1 |
| Carvalho, I; Corrado, AP; da Silva, JG; de Oliveira, JA; Hyppolito, MA; Ito, IY | 1 |
| Baussanne, I; Bussière, A; Décout, JL; Ennifar, E; Ganem-Elbaz, C; Halder, S; Mingeot-Leclercq, MP; Ouberai, M; Paris, JM; Riou, M | 1 |
| Chang, CW; Keller, K; Litke, A; Rai, R; Zhang, J | 1 |
| Anastasopoulou, P; Cottin, T; Katsoulis, IA; Kythreoti, G; Mavridis, I; Papakyriakou, A; Stathakis, CI; Vourloumis, D | 1 |
| Baussanne, I; Bussière, A; Décout, JL; Jolivalt, C; Mingeot-Leclercq, MP; Ouberai, M; Zimmermann, L | 1 |
| Di Giorgio, A; Duca, M; Tran, TP; Vo, DD | 1 |
| Barros R S, V; Das, I; Décout, JL; Désiré, J; El Khoury, M; Mingeot-Leclercq, MP; Sautrey, G; Zimmermann, L | 1 |
| Briée, F; Décout, JL; Kempf, J; Mingeot-Leclercq, MP; Swain, J; Zimmermann, L | 1 |
| AVECILLA, M | 1 |
| ADAM, W; STEITZ, K | 1 |
| GOLLNICK, N | 1 |
| QUILTER, TN | 1 |
| HOFFMAN, E | 1 |
| HABERMAN, S; MITCHELL, JD | 1 |
| NATHANSON, N | 1 |
| KOOIJ, R | 1 |
| KOWNACKI, VP; SERLIN, O | 1 |
| CHIDESTER, CG; SOKOLSKI, WT; YEAGER, RL | 1 |
| PIRILA, V; RANTANEN, AV | 1 |
| FROMM, SM; HSIANG, CM; MARTIN, RG; POTH, EJ; WISE, RI | 1 |
| PERRY, TL | 1 |
| Himeno, H; Konno, T; Kurita, D; Muto, A; Takahashi, T | 1 |
| Boons, GJ; Griffey, RH; Swayze, EE; Venot, A | 1 |
| Chaubey, B; Décout, JL; Désiré, J; Pandey, VN; Riguet, E; Tripathi, S | 1 |
| Cramer, SM; Dordick, JS; Hu, S; Moore, JA; Rege, K | 1 |
| Arai, Y; Horii, S; Mizokami, N; Nogami, I; Yoneda, M | 1 |
| Shahzad-ul-Hussan, S; Szilaghi, R; Weimar, T | 1 |
| Aboul-ela, F; François, B; Masquida, B; Murray, JB; Russell, RJ; Vicens, Q; Westhof, E | 1 |
| Hirukawa, S; Hu, GF; Olson, KA; Tsuji, T | 1 |
| Akagi, T; Hamasaki, K; Shionoya, H; Yajima, S | 1 |
| Hanko, VP; Rohrer, JS | 1 |
| Akiyama, Y; Hiraiwa, Y; Ikeda, D; Maebashi, K; Minowa, N; Usui, T | 1 |
| Chao, PW; Chow, CS | 1 |
| Baussanne, I; Chaubey, B; Décout, JL; Désiré, J; Pandey, VN; Tripathi, S | 1 |
| Alix, A; Bodlenner, A; Dumas, P; Ennifar, E; Marquet, R; Paillart, JC; Pale, P; Walter, P; Weibel, JM | 1 |
| Akagi, T; Hamasaki, K; Ikezawa, Y; Katou, T; Shionoya, H; Watanabe, K; Yajima, S | 1 |
| Childs-Disney, JL; Disney, MD; Labuda, LP; Paul, DJ; Poplawski, SG; Pushechnikov, A; Tran, T; Velagapudi, SP; Wu, M | 1 |
| Cai, L; Jin, HW; Mei, H; Xing, L; Yang, ZJ; Zhang, LH; Zhang, LR; Zhao, P | 1 |
| Aminova, O; Childs-Disney, JL; Disney, MD; Paul, DJ | 1 |
| Auclair, K; Gao, F; Yan, X | 1 |
| Hirukawa, S; Hu, GF; Hu, MG; Ibaragi, S; Li, S; Sadow, PM; Yoshioka, N | 1 |
| Jin, H; Li, M; Wang, Q; Xu, Y; Yang, Z; Zhang, L | 1 |
| Pang, LJ; Wang, D; Ye, XS; Zhang, LH; Zhou, J | 1 |
| Baussanne, I; Carmoy, N; Décout, JL; Halder, S; Le Gall, T; Lehn, P; Montier, T | 1 |
| Disney, MD; Tran, T | 1 |
| Bera, S; Schweizer, F; Zhanel, GG | 1 |
| Andreasen, KF; Arya, DP; Hyde-Volpe, D; Kumar, S; Ranjan, N | 1 |
| Andac, CA; Hornemann, U; Noyanalpan, N; Stringfellow, TC | 1 |
| Pan, PT; Wang, L; Wang, YC; Yang, LY; Yu, DH; Zhao, J | 1 |
| Cowan, JA; Patwardhan, A | 1 |
| Gómez-Pinto, I; Grandas, A; López-Senín, P; Marchán, V | 1 |
| Alsteens, D; Baussanne, I; Brasseur, R; Bussiere, A; Decout, JL; Dufrêne, YF; El Garch, F; Lins, L; Mingeot-Leclercq, MP; Ouberai, M; Riou, M | 1 |
| Chittapragada, M; Dayton, DL; Ham, YW; Marble, JB; Udumula, V | 1 |
| Berrée, F; Bordeau, V; Carboni, B; Felden, B; Gernigon, N | 1 |
| Catala, M; Dardel, F; Larue, V; Lecourt, T; Lombès, T; Micouin, L; Moumné, R; Prost, E; Tisné, C | 1 |
| Chen, W; Garneau-Tsodikova, S; Green, KD | 1 |
| Chaturvedi, N; Dixit, U; Manvar, D; Pandey, VN; Upadhyay, A | 1 |
| Brauch, S; Dörner, S; Heinke, R; Schaks, A; Stark, S; van Berkel, SS; van Delft, FL; Westermann, B | 1 |
| Carvalho, I; Corrado, AP; de Carvalho, MR; de Oliveira, JA; Hyppolito, MÂ; Kawano, DF; Pinsetta, FR | 1 |
| Arenz, C; Bastian, AA; Herrmann, A; Panduru, P; Warszawik, EM | 1 |
| Agostinho, A; Andremont, A; Harbarth, S; Haustein, T; Huttner, B; Pittet, D; Renzi, G; Schaerrer, D; Schrenzel, J; Stewardson, A; Uçkay, I | 1 |
| Bottero, V; Chandran, B; Dutta, S; Johnson, KE; Sadagopan, S; Veettil, MV | 1 |
| André, C; Guillaume, YC | 1 |
| Chen, J; Chopp, M; Lu, M; Ning, R; Roberts, C; Yan, T; Zacharek, A; Zhang, C | 1 |
| Hu, GF; Ibaragi, S; Kishimoto, K; Sasaki, A; Yoshida, S; Yoshioka, N | 1 |
| Buyck, JM; Decout, JL; Delbar, A; Deleu, M; Jeannot, K; Mingeot-Leclercq, MP; Sautrey, G; Souza Machado, L; Van Bambeke, F; Zimmermann, L | 1 |
| An, S; Hu, G; Liu, Y; Wu, Y; Zhang, X | 1 |
| Hamasaki, K; Ikezawa, Y; Inoue, R; Katou, T; Watanabe, K | 1 |
| Altman, RB; Blanchard, SC; Cate, JH; Garneau-Tsodikova, S; Green, KD; Pulk, A; Wasserman, MR; Zhou, Z; Zinder, JC | 1 |
| Carvalho, I; Corrado, AP; Prado, WA; Rossaneis, AC; Zamoner, LO | 1 |
| Hu, GF; Liu, YP; Wu, YL; Wu, YX; Zhang, XY | 1 |
| Décout, JL; Deleu, M; Dos Santos, AG; El Khoury, M; Lins, L; Mingeot-Leclercq, MP; Sautrey, G; Zimmermann, L | 1 |
| Fridman, M; Herzog, IM; Louzoun Zada, S | 1 |
| Allam, A; Alves de Sousa, R; Artaud, I; Dumont, E; Maigre, L; Pagès, JM; Vergalli, J | 1 |
| Feng, Y; Hu, GF; Li, Y; Shi, N; Wu, Y; Xu, Y | 1 |
| Borovika, A; Khomutnyk, Y; Lee, J; Nagorny, P | 1 |
| Berrisford, DJ; Gardiner, JM; Garvey, EP; Jackson, VJ; Simon, B; Slater, MJ; Walmsley, C | 1 |
| Concilio, MG; Ramesh, V; Yang, ZJ; Zhang, LH | 1 |
| Briée, F; Décout, JL; Dezanet, C; El Khoury, M; Flament, A; Mingeot-Leclercq, MP; Swain, J; Van Der Smissen, P | 1 |
| Auquière, M; Chalhoub, H; Décout, JL; Dezanet, C; Kempf, J; Mingeot-Leclercq, MP; Swain, J | 1 |
1 trial(s) available for framycetin and neamine
| Article | Year |
|---|---|
Decolonization of intestinal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae with oral colistin and neomycin: a randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Carrier State; Colistin; Double-Blind Method; Enterobacteriaceae; Enterobacteriaceae Infections; Feces; Female; Framycetin; Gastrointestinal Tract; Humans; Male; Middle Aged; Placebos; Treatment Outcome; Young Adult | 2013 |
87 other study(ies) available for framycetin and neamine
| Article | Year |
|---|---|
Modeling RNA-ligand interactions: the Rev-binding element RNA-aminoglycoside complex.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antiviral Agents; Binding Sites; Computer Simulation; Crystallography, X-Ray; Gene Products, rev; Humans; Ligands; Macromolecular Substances; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Protein Conformation; Rhinovirus; RNA, Viral; Structure-Activity Relationship | 1998 |
Which aminoglycoside ring is most important for binding? A hydropathic analysis of gentamicin, paromomycin, and analogues.
Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Escherichia coli; Gentamicins; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Paromomycin; RNA, Ribosomal, 16S; Structure-Activity Relationship; Thermodynamics | 2001 |
Study of aminoglycoside-nucleic acid interactions by an HPLC method.
Topics: Anti-Bacterial Agents; Binding Sites; Chromatography, High Pressure Liquid; DNA; Framycetin; Kanamycin; Neomycin; Netilmicin; RNA, Transfer | 2001 |
Synthesis of (+),(-)-neamine and their positional isomers as potential antibiotics.
Topics: Anti-Bacterial Agents; Binding Sites; Isomerism; Neomycin; Protein Biosynthesis; RNA, Ribosomal | 2003 |
Validation of automated docking programs for docking and database screening against RNA drug targets.
Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Databases, Factual; Ligands; Models, Molecular; Nucleic Acid Conformation; Quantitative Structure-Activity Relationship; RNA; RNA, Ribosomal; Software | 2004 |
Neamine dimers targeting the HIV-1 TAR RNA.
Topics: Aminoglycosides; Antiviral Agents; Dimerization; Drug Delivery Systems; Framycetin; Gene Products, tat; HIV Long Terminal Repeat; Inhibitory Concentration 50; Protein Binding; Structure-Activity Relationship | 2005 |
Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease.
Topics: Aminoglycosides; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Enzyme Inhibitors; Framycetin; Guanidine; Kinetics; Metalloendopeptidases; Structure-Activity Relationship | 2006 |
Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosa.
Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Kanamycin Kinase; Kinetics; Phosphorylation; Pseudomonas aeruginosa | 2007 |
Aminoglycoside antibiotic derivatives: preparation and evaluation of toxicity on cochlea and vestibular tissues and antimicrobial activity.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacteria; Cochlea; Guinea Pigs; Microscopy, Electron, Scanning; Structure-Activity Relationship; Vestibule, Labyrinth | 2007 |
Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives.
Topics: Anti-Bacterial Agents; Calorimetry; Framycetin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship | 2010 |
Synthesis of novel aminoglycosides via allylic azide rearrangement for investigating the significance of 2'-amino group.
Topics: Aminoglycosides; Anti-Bacterial Agents; Azides; Carbohydrate Sequence; Microbial Sensitivity Tests; Molecular Sequence Data; Spectrometry, Mass, Electrospray Ionization | 2010 |
Second generation analogs of rigid 6,7-spiro scaffolds targeting the bacterial ribosome.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria; Binding Sites; Computer Simulation; RNA, Ribosomal, 16S; Spiro Compounds | 2010 |
Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues.
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Framycetin; Gram-Negative Bacteria; Microbial Sensitivity Tests; Naphthalenes; Staphylococcus aureus; Structure-Activity Relationship | 2013 |
Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting.
Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; DEAD-box RNA Helicases; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Models, Molecular; Molecular Sequence Data; Neoplasms; Ribonuclease III; Ribosomes; Tetracyclines | 2015 |
New Broad-Spectrum Antibacterial Amphiphilic Aminoglycosides Active against Resistant Bacteria: From Neamine Derivatives to Smaller Neosamine Analogues.
Topics: Aminoglycosides; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Framycetin; Glucosamine; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Surface-Active Agents | 2016 |
Broad-spectrum antibacterial amphiphilic aminoglycosides: A new focus on the structure of the lipophilic groups extends the series of active dialkyl neamines.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cell Survival; Dose-Response Relationship, Drug; Eukaryotic Cells; Framycetin; Humans; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Structure-Activity Relationship; Surface-Active Agents | 2018 |
Intraperitoneal neomycin as an adjunct in the surgical management of generalized peritonitis; report of five cases.
Topics: Framycetin; Health Services; Humans; Neomycin; Peritonitis | 1955 |
[Neomycin as a bacteriostatic supplement to fungus culture media].
Topics: Communications Media; Culture Media; Dietary Supplements; Framycetin; Fungi; Neomycin; Tunica Media | 1956 |
[A new hydrocortisone ointment with neomycin as an antibiotic addition].
Topics: Anti-Bacterial Agents; Framycetin; Humans; Hydrocortisone; Neomycin; Skin Diseases | 1956 |
The use of neomycin as a cold sterilizing agent.
Topics: Framycetin; Humans; Neomycin; Sterilization | 1957 |
Intraperitoneal and extraperitoneal neomycin as a topical and irrigating agent.
Topics: Framycetin; Humans; Neomycin; Surgical Procedures, Operative | 1959 |
The limited usefulness of neomycin as a cold-sterilizing agent.
Topics: Antisepsis; Asepsis; Framycetin; Humans; Neomycin; Sterilization | 1959 |
Neomycin as a selective agent in culture media.
Topics: Culture Media; Framycetin; Neomycin | 1959 |
Allergic contact dermatitis due to neomycin. Cross-sensitivity with other antibiotics; and positive patch tests with the isomeric compounds neomycin B and neomycin C and with neamine.
Topics: Anti-Bacterial Agents; Dermatitis, Allergic Contact; Dermatitis, Contact; Dermatologic Agents; Framycetin; Humans; Neomycin; Patch Tests | 1961 |
Intraperitoneal neomycin as a cause of apnea.
Topics: Apnea; Framycetin; Neomycin | 1960 |
Cross-dependence between neamine and other basic antibiotics.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Erythromycin; Escherichia coli; Framycetin; Kanamycin; Mycobacterium; Neomycin; Salmonella; Staphylococcus; Streptomycin; Vancomycin | 1962 |
Root canal treatment with bacitracin-neomycin as cause of flare-up of allergic eczema.
Topics: Bacitracin; Dental Pulp Cavity; Dermatitis, Atopic; Dermatitis, Contact; Eczema; Framycetin; Humans; Neomycin; Root Canal Therapy | 1960 |
A critical analysis of neomycin as an intestinal antiseptic.
Topics: Anti-Infective Agents, Local; Framycetin; Humans; Intestines; Neomycin | 1951 |
Failure of neomycin as an adjuvant to streptomycin in tuberculous meningitis.
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Anti-Bacterial Agents; Antibiotics, Antitubercular; Framycetin; Neomycin; Streptomycin; Tuberculosis; Tuberculosis, Meningeal | 1952 |
A minimum structure of aminoglycosides that causes an initiation shift of trans-translation.
Topics: Aminoglycosides; Frameshifting, Ribosomal; Framycetin; Hygromycin B; Mutation; Paromomycin; Protein Biosynthesis; RNA, Bacterial; Streptomycin | 2004 |
Disaccharide mimetics of the aminoglycoside antibiotic neamine.
Topics: Aminoglycosides; Carbohydrate Sequence; Crystallography, X-Ray; Disaccharides; Framycetin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Sequence Data; RNA; Structure-Activity Relationship | 2004 |
A peptide nucleic acid-neamine conjugate that targets and cleaves HIV-1 TAR RNA inhibits viral replication.
Topics: Aminoglycosides; Anti-HIV Agents; Binding Sites; Biochemistry; Cells, Cultured; Drug Evaluation, Preclinical; Framycetin; HIV Long Terminal Repeat; HIV Reverse Transcriptase; HIV-1; Humans; Lymphocytes; Peptide Nucleic Acids; RNA, Viral; Structure-Activity Relationship; Virus Replication | 2004 |
Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands.
Topics: Aminoglycosides; Cations; Chromatography, Ion Exchange; Combinatorial Chemistry Techniques; Cytochromes c; DNA; Framycetin; Kanamycin; Kinetics; Ligands; Muramidase; Polyamines; Proteins | 2004 |
New antibiotic produced by bacteria, 5-beta-D-xylofuranosylneamine.
Topics: Acylation; Aminoglycosides; Anti-Bacterial Agents; Bacillus; Butirosin Sulfate; Fermentation; Framycetin; Hydrolysis | 1974 |
The RNA-bound conformation of neamine as determined by transferred NOE experiments.
Topics: Aminoglycosides; Binding Sites; Framycetin; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; RNA | 2005 |
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
Topics: Adenine; Aminoglycosides; Anti-Bacterial Agents; Anticodon; Base Sequence; Binding Sites; Codon; Crystallography, X-Ray; Framycetin; Gentamicins; Kanamycin; Models, Molecular; Oligoribonucleotides; Paromomycin; Ribosomes; Ribostamycin; RNA, Ribosomal, 16S | 2005 |
Neamine inhibits xenografic human tumor growth and angiogenesis in athymic mice.
Topics: Active Transport, Cell Nucleus; Aminoglycosides; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Nucleus; Cell Proliferation; Endothelial Cells; Framycetin; Humans; Mice; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Ribonuclease, Pancreatic; Umbilical Veins; Xenograft Model Antitumor Assays | 2005 |
Neamine derivatives having a nucleobase with a lysine or an arginine as a linker, their synthesis and evaluation as potential inhibitors for HIV TAR-Tat.
Topics: Amino Acid Sequence; Aminoglycosides; Anti-HIV Agents; Arginine; Framycetin; Gene Products, tat; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Spectrometry, Fluorescence | 2006 |
Determination of neomycin sulfate and impurities using high-performance anion-exchange chromatography with integrated pulsed amperometric detection.
Topics: Aminoglycosides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Drug Contamination; Electrochemistry; Framycetin; Neomycin; Ointments; Reference Standards; Reproducibility of Results; Temperature | 2007 |
Synthesis and antibacterial activity of novel neamine derivatives.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbohydrate Conformation; Framycetin; Methicillin Resistance; Models, Molecular; Molecular Conformation; Staphylococcus aureus | 2006 |
Monitoring aminoglycoside-induced conformational changes in 16S rRNA through acrylamide quenching.
Topics: 2-Aminopurine; Acrylamide; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Binding Sites; Fluorescence; Framycetin; Nucleic Acid Conformation; Paromomycin; RNA, Ribosomal, 16S; Spectrometry, Mass, Electrospray Ionization | 2007 |
Mechanism of RNA cleavage catalyzed by sequence specific polyamide nucleic acid-neamine conjugate.
Topics: Aminoglycosides; Cell Line; Framycetin; HIV Long Terminal Repeat; HIV-1; Humans; Hydrogen-Ion Concentration; Nylons; Oligonucleotides, Antisense; Response Elements; RNA, Viral | 2007 |
Synthesis of a neamine dimer targeting the dimerization initiation site of HIV-1 RNA.
Topics: Aminoglycosides; Anti-HIV Agents; Dimerization; Framycetin; HIV-1; Molecular Structure; Nucleic Acid Conformation; RNA, Viral; Transcription Initiation Site | 2007 |
Nucleobase modified neamines, their synthesis and binding specificity for HIV TAR RNA.
Topics: Aminoglycosides; Framycetin; HIV Long Terminal Repeat; Purines; Pyrimidines; RNA, Viral | 2007 |
Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners.
Topics: Alkynes; Aminoglycosides; Azides; Base Pairing; Carbohydrate Conformation; Combinatorial Chemistry Techniques; Framycetin; Kanamycin; Ligands; Nucleic Acid Conformation; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Reverse Transcriptase Polymerase Chain Reaction; RNA; Small Molecule Libraries; Tobramycin; Transcription, Genetic | 2008 |
Studies on the synthesis of neamine-dinucleosides and neamine-PNA conjugates and their interaction with RNA.
Topics: Adenine; Chemistry, Pharmaceutical; Drug Design; Framycetin; Kinetics; Models, Chemical; Nucleosides; Peptide Nucleic Acids; Phosphates; Protein Binding; RNA; RNA, Ribosomal, 16S; Software; Static Electricity; Surface Plasmon Resonance | 2008 |
Two-dimensional combinatorial screening identifies specific 6'-acylated kanamycin A- and 6'-acylated neamine-RNA hairpin interactions.
Topics: Acylation; Adenine; Base Sequence; Combinatorial Chemistry Techniques; Cytosine; Drug Evaluation, Preclinical; Framycetin; Inverted Repeat Sequences; Kanamycin; Ligands; RNA; Substrate Specificity | 2008 |
Synthesis of a phosphonate-linked aminoglycoside-coenzyme a bisubstrate and use in mechanistic studies of an enzyme involved in aminoglycoside resistance.
Topics: Acetyltransferases; Aminoglycosides; Catalysis; Coenzyme A; Drug Resistance, Bacterial; Enterococcus faecium; Framycetin; Organophosphonates | 2009 |
Neamine inhibits prostate cancer growth by suppressing angiogenin-mediated rRNA transcription.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Framycetin; Humans; Male; Mice; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Ribonuclease, Pancreatic; RNA, Ribosomal; Transcription, Genetic; Xenograft Model Antitumor Assays | 2009 |
Synthesis and evaluation of novel neamine derivatives effectively targeting to RNA.
Topics: Anti-HIV Agents; Base Sequence; Binding Sites; Drug Delivery Systems; Drug Evaluation, Preclinical; Framycetin; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; RNA, Viral | 2009 |
Synthesis of neamine-derived pseudodisaccharides by stereo- and regio-selective functional group transformations.
Topics: Anti-Bacterial Agents; Biomimetics; Disaccharides; Framycetin; Glycosylation; Hexosamines; Pseudomonas aeruginosa; RNA; Stereoisomerism; Substrate Specificity | 2009 |
Synthesis and transfection properties of a series of lipidic neamine derivatives.
Topics: Cell Line; Framycetin; Humans; Lipids; Luciferases; Plasmids; Structure-Activity Relationship; Transfection | 2009 |
Two-dimensional combinatorial screening of a bacterial rRNA A-site-like motif library: defining privileged asymmetric internal loops that bind aminoglycosides.
Topics: Amino Acyl-tRNA Synthetases; Aminoglycosides; Binding Sites; Combinatorial Chemistry Techniques; Drug Delivery Systems; Framycetin; Gene Library; Kanamycin; Nucleic Acid Conformation; Oligonucleotides; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; RNA, Ribosomal, 16S; Tobramycin | 2010 |
Antibacterial activities of aminoglycoside antibiotics-derived cationic amphiphiles. Polyol-modified neomycin B-, kanamycin A-, amikacin-, and neamine-based amphiphiles with potent broad spectrum antibacterial activity.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Cations; Framycetin; Kanamycin; Male; Mice; Polymers; Structure-Activity Relationship; Surface-Active Agents | 2010 |
Aminoglycoside binding to Oxytricha nova telomeric DNA.
Topics: Aminoglycosides; Animals; Base Sequence; Calorimetry; DNA, Protozoan; Framycetin; Guanine; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Neomycin; Oxytricha; Paromomycin; Ribostamycin; Spectrophotometry, Ultraviolet | 2010 |
NMR and amber analysis of the neamine pharmacophore for the design of novel aminoglycoside antibiotics.
Topics: Anti-Bacterial Agents; Drug Design; Framycetin; Magnetic Resonance Spectroscopy; Models, Molecular | 2011 |
Neamine inhibits cell proliferation, migration, and invasion in H7402 human hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Framycetin; Humans; Liver Neoplasms; Neoplasm Invasiveness | 2010 |
Influence of charge and structure on the coordination chemistry of copper aminoglycosides.
Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Copper; Framycetin; Kanamycin; Magnetic Resonance Spectroscopy; Molecular Structure; Paromomycin; Spectrophotometry, Ultraviolet; Static Electricity; Tobramycin | 2011 |
Identification of ligands for the Tau exon 10 splicing regulatory element RNA by using dynamic combinatorial chemistry.
Topics: Chromosomes, Human, Pair 17; Circular Dichroism; Combinatorial Chemistry Techniques; Dementia; Exons; Fluorometry; Framycetin; Humans; Introns; Ligands; Parkinsonian Disorders; RNA; RNA Precursors; RNA Splicing; Tauopathies | 2011 |
The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative?
Topics: Anti-Bacterial Agents; Binding, Competitive; Cell Membrane; Drug Resistance, Bacterial; Escherichia coli; Framycetin; Humans; Lipid Bilayers; Lipopolysaccharides; Liposomes; Microbial Sensitivity Tests; Microscopy, Atomic Force; Molecular Structure; Pseudomonas aeruginosa; Pseudomonas Infections | 2011 |
Conjugate of neamine and 2-deoxystreptamine mimic connected by an amide bond.
Topics: Amides; Carboxylic Acids; Framycetin; Hexosamines; Molecular Conformation; Molecular Mimicry; RNA; Stereoisomerism | 2011 |
Synthesis and antibacterial activity of novel neamine derivatives: preponderant role of the substituent position on the neamine core.
Topics: Anti-Bacterial Agents; Escherichia coli; Framycetin; Microbial Viability; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship | 2012 |
Investigation of RNA-ligand interactions by 19F NMR spectroscopy using fluorinated probes.
Topics: Aminoglycosides; Fluorescent Dyes; Fluorine; Framycetin; Ligands; Magnetic Resonance Spectroscopy; Neomycin; Paromomycin; RNA | 2012 |
Cosubstrate tolerance of the aminoglycoside resistance enzyme Eis from Mycobacterium tuberculosis.
Topics: Acetyltransferases; Acyl Coenzyme A; Acylation; Amikacin; Antigens, Bacterial; Bacterial Proteins; Chromatography, Liquid; Chromatography, Thin Layer; Framycetin; Kanamycin Resistance; Mass Spectrometry; Mycobacterium tuberculosis; Netilmicin; Recombinant Proteins; Substrate Specificity | 2012 |
Affinity capture and identification of host cell factors associated with hepatitis C virus (+) strand subgenomic RNA.
Topics: Biotinylation; Cell Line, Tumor; Chromatography, Affinity; Chromatography, Liquid; Framycetin; Gene Expression Regulation, Viral; Genome, Viral; Hepacivirus; Hepatocytes; Host-Pathogen Interactions; Humans; Peptide Nucleic Acids; Protein Isoforms; Replicon; RNA, Viral; Tandem Mass Spectrometry; Viral Nonstructural Proteins; Virus Replication | 2013 |
CuAAC-mediated diversification of aminoglycoside-arginine conjugate mimics by non-reducing di- and trisaccharides.
Topics: Aminoglycosides; Anti-Bacterial Agents; Arginine; Bacillus subtilis; Carbohydrate Conformation; Catalysis; Click Chemistry; Framycetin; Glycoconjugates; Guanidines; Kanamycin; Molecular Docking Simulation; Molecular Mimicry; Sucrose; Trehalose; Trisaccharides | 2013 |
Synthesis of neamine-based pseudodisaccharides as potential vestibulotoxic agents to treat vertigo in Ménière's disease.
Topics: Aminoglycosides; Animals; Azides; Chemistry Techniques, Synthetic; Cochlea; Disaccharides; Drug Evaluation, Preclinical; Evoked Potentials, Auditory, Brain Stem; Framycetin; Guinea Pigs; Hair Cells, Auditory; Humans; Meniere Disease; Microscopy, Electron, Scanning; Molecular Mimicry; Molecular Structure; Vertigo | 2013 |
Regioselective diazo-transfer reaction at the C3-position of the 2-desoxystreptamine ring of neamine antibiotics.
Topics: Anti-Bacterial Agents; Azides; Framycetin; Imidazoles; Stereoisomerism | 2013 |
Kaposi's sarcoma-associated herpesvirus-positive primary effusion lymphoma tumor formation in NOD/SCID mice is inhibited by neomycin and neamine blocking angiogenin's nuclear translocation.
Topics: Animals; Antineoplastic Agents; Ascites; Body Weight; Cell Line, Tumor; Disease Models, Animal; Framycetin; Herpesvirus 8, Human; Lymphoma, Primary Effusion; Mice; Mice, SCID; Neomycin; Ribonuclease, Pancreatic; Spleen; Survival Analysis; Treatment Outcome | 2013 |
Fast enantioseparation by HPLC on a modified carbon nanotube monolithic stationary phase with a pyrenyl aminoglycoside derivative.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Framycetin; Nanotubes, Carbon; Pyrenes; Stereoisomerism | 2013 |
Neamine induces neuroprotection after acute ischemic stroke in type one diabetic rats.
Topics: Angiopoietins; Animals; Blood Pressure; Blood-Brain Barrier; Body Temperature; Caspase 3; Diabetes Mellitus, Experimental; Disease Models, Animal; Extravasation of Diagnostic and Therapeutic Materials; Framycetin; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Severity of Illness Index; Time Factors; Toll-Like Receptor 4 | 2014 |
Neamine inhibits oral cancer progression by suppressing angiogenin-mediated angiogenesis and cancer cell proliferation.
Topics: Angiogenesis Inducing Agents; Animals; Cell Line, Tumor; Cell Proliferation; Disease Progression; Framycetin; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Mouth Neoplasms; Neovascularization, Pathologic; Protein Transport; Ribonuclease, Pancreatic; Xenograft Model Antitumor Assays | 2014 |
New amphiphilic neamine derivatives active against resistant Pseudomonas aeruginosa and their interactions with lipopolysaccharides.
Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Cell Membrane; Cell Membrane Permeability; Colistin; Drug Resistance, Multiple, Bacterial; Framycetin; Humans; Hydrophobic and Hydrophilic Interactions; Lipopolysaccharides; Microbial Sensitivity Tests; Naphthalenes; Pseudomonas aeruginosa; Structure-Activity Relationship | 2014 |
Pharmacokinetics of neamine in rats and anti-cervical cancer activity in vitro and in vivo.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Area Under Curve; Biological Availability; Cell Proliferation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Framycetin; Half-Life; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Ribonuclease, Pancreatic; Tissue Array Analysis; Up-Regulation; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Nucleobase modified neamines with a lysine as a linker, their inhibition specificity for TAR-Tat derived from HIV-1.
Topics: Adenine; Cytosine; Framycetin; Guanine; HIV Long Terminal Repeat; HIV-1; Lysine; Molecular Structure; Structure-Activity Relationship; tat Gene Products, Human Immunodeficiency Virus; Thymine | 2015 |
Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Escherichia coli; Escherichia coli Proteins; Framycetin; Neomycin; Paromomycin; Ribosome Subunits, Large, Bacterial; Ribosome Subunits, Small, Bacterial; Ribosomes; Ribostamycin; RNA, Bacterial; Rotation | 2015 |
Neamine and 2-deoxystreptamine neomycin derivatives exhibit antinociceptive activity in rat models of phasic, incision and neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Framycetin; Hexosamines; Injections, Spinal; Male; Molecular Structure; Neuralgia; Nociception; Nociceptive Pain; Pain Measurement; Pain Threshold; Pain, Postoperative; Rats, Wistar; Reaction Time; Structure-Activity Relationship; Time Factors | 2015 |
Neamine inhibits growth of pancreatic cancer cells in vitro and in vivo.
Topics: Adult; Animals; Antibiotics, Antineoplastic; Carcinoma; Cell Line, Tumor; Cell Proliferation; Framycetin; Humans; Ki-67 Antigen; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Pancreatic Neoplasms; Platelet Endothelial Cell Adhesion Molecule-1; Ribonuclease, Pancreatic | 2016 |
Negatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY.
Topics: Cardiolipins; Framycetin; Phosphatidylglycerols; Pseudomonas aeruginosa | 2016 |
Effects of 5-O-Ribosylation of Aminoglycosides on Antimicrobial Activity and Selective Perturbation of Bacterial Translation.
Topics: Aminoglycosides; Anti-Bacterial Agents; Escherichia coli Proteins; Framycetin; Gram-Negative Bacteria; Kanamycin; Microbial Sensitivity Tests; Ribose; Structure-Activity Relationship; Trisaccharides | 2016 |
New amphiphilic neamine conjugates bearing a metal binding motif active against MDR E. aerogenes Gram-negative bacteria.
Topics: Anti-Bacterial Agents; Cell Membrane Permeability; Cephalosporins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacter aerogenes; Escherichia coli; Framycetin; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Organometallic Compounds | 2017 |
Sub-chronic 90-day toxicity of neamine in SD rats and its anti-liver cancer activity in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Framycetin; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Liver Neoplasms, Experimental; Male; Mice; No-Observed-Adverse-Effect Level; Rats; Rats, Sprague-Dawley; Toxicity Tests, Subchronic | 2017 |
Chiral phosphoric acid-catalyzed desymmetrizative glycosylation of 2-deoxystreptamine and its application to aminoglycoside synthesis.
Topics: Aminoglycosides; Catalysis; Framycetin; Glycosylation; Hexosamines; Kanamycin; Phosphoric Acids; Stereoisomerism | 2017 |
Evaluation of neomycin analogues for HIV-1 RRE RNA recognition identifies enhanced activity simplified neamine analogues.
Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Framycetin; HIV-1; Molecular Structure; Neomycin; Response Elements; RNA, Viral; Structure-Activity Relationship | 2019 |
Synthesis and Evaluation of Novel Neamine-Nucleoside Conjugates as Potential Antibiotic Targets for Escherichia coli 16S Ribosomal RNA.
Topics: Anti-Bacterial Agents; Escherichia coli; Framycetin; Gene Expression Regulation, Bacterial; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; RNA, Bacterial; RNA, Ribosomal, 16S | 2019 |
Antimicrobial activity of amphiphilic neamine derivatives: Understanding the mechanism of action on Gram-positive bacteria.
Topics: Anti-Bacterial Agents; Bacillus subtilis; Cell Membrane; Cell Membrane Permeability; Framycetin; Gram-Positive Bacteria; Lipopolysaccharides; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship; Surface-Active Agents; Teichoic Acids | 2019 |
Interest of Homodialkyl Neamine Derivatives against Resistant
Topics: Allyl Compounds; Anti-Bacterial Agents; Cell Membrane; Cell Membrane Permeability; Drug Resistance, Bacterial; Escherichia coli; Framycetin; Gram-Negative Bacteria; Lipopolysaccharides; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2021 |