fr 74366 has been researched along with ponalrestat in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kador, PF; Lee, YS; Pearlstein, R | 1 |
| Carper, DA; Hohman, TC; Kitchen, D; Malamas, MS; Nilakantan, R; Singh, SB | 1 |
| Degliesposti, G; Ferrari, AM; Rastelli, G; Sgobba, M | 1 |
3 other study(ies) available for fr 74366 and ponalrestat
| Article | Year |
|---|---|
Molecular modeling studies of aldose reductase inhibitors.
Topics: Aldehyde Reductase; Carboxylic Acids; Models, Molecular; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 1994 |
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.
Topics: Aldehyde Reductase; Benzothiazoles; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phthalazines; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2000 |
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors.
Topics: Aldehyde Reductase; Binding Sites; Binding, Competitive; Computer Simulation; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Inhibitory Concentration 50; Models, Biological; Molecular Structure; Thermodynamics | 2007 |