Page last updated: 2024-09-02

fr 139317 and ng-nitroarginine methyl ester

fr 139317 has been researched along with ng-nitroarginine methyl ester in 11 studies

Study Comparison

Studies
(fr 139317)
Trials
(fr 139317)
Recent Studies (post-2010)
(fr 139317)
Studies
(ng-nitroarginine methyl ester)
Trials
(ng-nitroarginine methyl ester)
Recent Studies (post-2010)
(ng-nitroarginine methyl ester)
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Protein Interaction Comparison

ProteinTaxonomyfr 139317 (IC50)ng-nitroarginine methyl ester (IC50)
Neutrophil elastaseHomo sapiens (human)2.7
Nitric oxide synthase, endothelialBos taurus (cattle)100
Nitric oxide synthase, endothelialHomo sapiens (human)2.1
Nitric oxide synthase, brainHomo sapiens (human)1.1167
Nitric oxide synthase, inducibleMus musculus (house mouse)16.8875
Nitric oxide synthase, inducibleHomo sapiens (human)60008.8
Collagenase 3Homo sapiens (human)2.7

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (90.91)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baird, M; MacLean, MR; McCulloch, KM1
Cobb, VJ; Dashwood, MR; Marr, CG; McQueen, DS1
Asano, H; Mizuguchi, T; Shimoyama, N; Yamamoto, T1
Flammer, J; Lüscher, TF; Meyer, P1
Antunes, E; Boin, I; de Nucci, G; Donato, JL; Faro, R; Grassi-Kassisse, DM; Opgenorth, TJ; Withrington, PG; Zatz, R1
De Nucci, G; Fujihara, CK; Zatz, R1
Filep, JG1
Ebara, T; Iwao, H; Kim, S; Matsuura, T; Miura, K; Yamanaka, S; Yukimura, T1
Antunes, E; Boin, I; de Nucci, G; Faro, R; Ferraz, JG; Grassi-Kassise, DM; Opgenorth, TJ; Withrington, PG1
Hisa, H; Matsui, T; Ono, N; Satoh, S; Suzuki-Kusaba, M; Yoshida, M1
Chen, HI; Hsieh, NK; Liu, DD; Yang, YL1

Other Studies

11 other study(ies) available for fr 139317 and ng-nitroarginine methyl ester

ArticleYear
Endothelin ETA- and ETB-receptor-mediated vasoconstriction in rat pulmonary arteries and arterioles.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:5

    Topics: Animals; Arginine; Arterioles; Azepines; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Indoles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Rats; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms

1994
Effects of endothelins on respiration and arterial chemoreceptor activity in anaesthetised rats.
    Advances in experimental medicine and biology, 1994, Volume: 360

    Topics: Anesthesia, General; Animals; Arginine; Arteries; Azepines; Blood Pressure; Carotid Body; Chemoreceptor Cells; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Receptors, Endothelin; Respiration; Sodium Cyanide; Solitary Nucleus; Sympathetic Nervous System

1994
Analysis of the role of endothelin-A and endothelin-B receptors on nociceptive information transmission in the spinal cord with FR139317, an endothelin-A receptor antagonist, and sarafotoxin S6c, an endothelin-B receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1

    Topics: Animals; Arginine; Azepines; Behavior, Animal; Endothelin Receptor Antagonists; Endothelins; Formaldehyde; Indoles; Male; NG-Nitroarginine Methyl Ester; Pain; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Viper Venoms

1994
Endothelium-dependent regulation of the ophthalmic microcirculation in the perfused porcine eye: role of nitric oxide and endothelins.
    Investigative ophthalmology & visual science, 1993, Volume: 34, Issue:13

    Topics: Animals; Arginine; Azepines; Blood Flow Velocity; Bradykinin; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Eye; Indoles; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Swine; Vasoconstrictor Agents

1993
Role of endothelin ETA and ETB receptors in the arterial vasculature of the isolated canine liver.
    Journal of cardiovascular pharmacology, 1995, Volume: 26 Suppl 3

    Topics: Animals; Arginine; Azepines; Dogs; Endothelins; Female; Hemoglobins; Hepatic Artery; In Vitro Techniques; Indoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Viper Venoms

1995
Do ETA receptors participate in the hemodynamic and renal effects of chronic nitric oxide blockade?
    Journal of cardiovascular pharmacology, 1995, Volume: 26 Suppl 3

    Topics: Animals; Arginine; Azepines; Hemodynamics; Indoles; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin

1995
Endogenous endothelin modulates blood pressure, plasma volume, and albumin escape after systemic nitric oxide blockade.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:1 Pt 1

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Bosentan; Data Interpretation, Statistical; Endothelin Receptor Antagonists; Endothelin-1; Hydralazine; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasma Volume; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Serum Albumin; Sulfonamides; Time Factors; Vasodilator Agents

1997
Renal vascular effects of the selective endothelin receptor antagonists in anaesthetized rats.
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Animals; Azepines; Blood Pressure; Cyclooxygenase Inhibitors; Endothelin Receptor Antagonists; Enzyme Inhibitors; Ibuprofen; Indoles; Kidney; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Renal Circulation; Vasoconstriction

1997
Characterization of endothelin receptors in isolated, perfused human spleen.
    Journal of cardiovascular pharmacology, 1998, Volume: 31 Suppl 1

    Topics: Adult; Azepines; Cyclooxygenase Inhibitors; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Indomethacin; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Perfusion; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Spleen

1998
Renal effects of endothelin in anesthetized rabbits.
    European journal of pharmacology, 1998, Oct-23, Volume: 359, Issue:2-3

    Topics: Analysis of Variance; Anesthesia; Animals; Azepines; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Glomerular Filtration Rate; Hydrazines; Indoles; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Oligopeptides; Piperidines; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Renal Circulation; Sodium; Urination

1998
Endothelin and gelatinases in renal changes following blockade of nitric oxide synthase in hypertensive rats.
    The Chinese journal of physiology, 2008, Jun-30, Volume: 51, Issue:3

    Topics: Animals; Azepines; Blood Urea Nitrogen; Collagen; Creatinine; Cyclic GMP; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gelatinases; Glomerular Filtration Rate; Hypertension; Indoles; Kidney; Matrix Metalloproteinases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Tissue Inhibitor of Metalloproteinase-2

2008