fr 139317 has been researched along with irl 2500 in 6 studies
| Studies (fr 139317) | Trials (fr 139317) | Recent Studies (post-2010) (fr 139317) | Studies (irl 2500) | Trials (irl 2500) | Recent Studies (post-2010) (irl 2500) |
|---|---|---|---|---|---|
| 219 | 0 | 8 | 18 | 0 | 10 |
| 219 | 0 | 8 | 18 | 0 | 10 |
| 219 | 0 | 8 | 18 | 0 | 10 |
| 219 | 0 | 8 | 18 | 0 | 10 |
| 219 | 0 | 8 | 18 | 0 | 10 |
| 219 | 0 | 8 | 18 | 0 | 10 |
| Protein | Taxonomy | fr 139317 (IC50) | irl 2500 (IC50) |
|---|---|---|---|
| Endothelin receptor type B | Homo sapiens (human) | 0.0013 | |
| Endothelin-1 receptor | Homo sapiens (human) | 0.094 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Acher, FC; Anne, C; Bertrand, HO; Biot, C; Cabaye, A; Dairou, J; Dansette, PM; Debacker, C; Dubois, L; Fanget, I; Froissart, R; Gasnier, B; Gilormini, PA; Goupil-Lamy, A; McCort-Tranchepain, I; Pietrancosta, N | 1 |
| Edvinsson, L; Hansen-Schwartz, J | 1 |
| Adner, M; Edvinsson, L; Shankley, N | 1 |
| Leung, SW; Lim, SL; Man, RY; Pang, CC | 1 |
| Bratz, IN; Damron, DS; Guarini, G; Haney, RM; Meszaros, JG; Ohanyan, VA; Raman, P; Talasila, PK; Thodeti, CK | 1 |
| Fuka, M; Koyama, Y; Matsuyama, E; Michinaga, S; Nagase, M; Seno, N; Yamamoto, Y; Yamanaka, D | 1 |
6 other study(ies) available for fr 139317 and irl 2500
| Article | Year |
|---|---|
Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.
Topics: Amino Acids; Animals; Dose-Response Relationship, Drug; HEK293 Cells; HeLa Cells; Humans; Ligands; Lysosomes; Molecular Docking Simulation; Organic Anion Transporters; Protein Structure, Secondary; Rats; Symporters | 2020 |
Increased sensitivity to ET-1 in rat cerebral arteries following organ culture.
Topics: Animals; Azepines; Basilar Artery; Biphenyl Compounds; Dipeptides; Endothelin Receptor Antagonists; Endothelin-1; Indoles; Organ Culture Techniques; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2000 |
Evidence that ET-1, but not ET-3 and S6b, ET(A)-receptor mediated contractions in isolated rat mesenteric arteries are modulated by co-activation of ET(B) receptors.
Topics: Adenylyl Cyclases; Animals; Azepines; Biphenyl Compounds; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction; Viper Venoms | 2001 |
Use of A-192621 and IRL-2500 to unmask the mesenteric and renal vasodilator role of endothelin ET(B) receptors.
Topics: Animals; Azepines; Biphenyl Compounds; Dipeptides; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hemodynamics; Indoles; Male; Peptide Fragments; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Renal Circulation; Splanchnic Circulation; Vasoconstriction; Vasodilation | 2002 |
Endothelin-mediated in vivo pressor responses following TRPV1 activation.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Azepines; Biphenyl Compounds; Blood Pressure; Capsaicin; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Femoral Artery; Indoles; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Receptor, Endothelin A; Receptor, Endothelin B; TRPV Cation Channels; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice.
Topics: Animals; Azepines; Biphenyl Compounds; Blood-Brain Barrier; Blotting, Western; Brain Edema; Brain Injuries; Cerebrum; Cold Temperature; Dipeptides; Endothelin Receptor Antagonists; Endothelins; Glial Fibrillary Acidic Protein; Indoles; Male; Mice; Oligopeptides; Piperidines; Real-Time Polymerase Chain Reaction; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2014 |