fr 120480 has been researched along with sincalide in 6 studies
| Studies (fr 120480) | Trials (fr 120480) | Recent Studies (post-2010) (fr 120480) | Studies (sincalide) | Trials (sincalide) | Recent Studies (post-2010) (sincalide) |
|---|---|---|---|---|---|
| 32 | 0 | 8 | 4,015 | 72 | 533 |
| Protein | Taxonomy | fr 120480 (IC50) | sincalide (IC50) |
|---|---|---|---|
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | 0.0006 | |
| Cholecystokinin receptor type A | Homo sapiens (human) | 0.0006 | |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | 0.001 | |
| Gastrin/cholecystokinin type B receptor | Mus musculus (house mouse) | 0.0008 | |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, H; Kadowaki, M; Matsuo, M; Nakarai, T; Sato, Y; Sogabe, H; Tokoro, K; Tomoi, M; Yoshida, K | 1 |
| Moriyoshi, Y; Shiratori, K; Takeuchi, T; Watanabe, S | 1 |
| Kihara, Y; Otsuki, M | 1 |
| Itoh, H; Kinoshita, T; Matsuo, T; Satoh, Y; Sogabe, H; Tada, T; Takaya, T; Yoshida, K | 1 |
| Akiyama, T; Otsuki, M | 1 |
| Chijiiwa, Y; Iwakiri, Y; Motomura, Y; Nawata, H | 1 |
6 other study(ies) available for fr 120480 and sincalide
| Article | Year |
|---|---|
Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide.
Topics: Amylases; Animals; Benzodiazepinones; Female; Gastric Emptying; Guinea Pigs; Indoles; Male; Mice; Mice, Inbred ICR; Proglumide; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide | 1994 |
Effect of a novel cholecystokinin receptor antagonist, FK480, administered intraduodenally, on pancreatic secretion in rats.
Topics: Amylases; Animals; Benzodiazepinones; Caseins; Duodenum; Indoles; Male; Pancreas; Pancreatic Juice; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide | 1995 |
Different inhibitory effects of the newly developed CCK receptor antagonists FK480 and KSG-504 on pancreatic exocrine and endocrine secretion in the isolated perfused rat pancreas.
Topics: Animals; Benzodiazepinones; In Vitro Techniques; Indoles; Insulin; Insulin Secretion; Male; Naphthalenes; Pancreas; Pentanoic Acids; Perfusion; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide | 1995 |
Studies on a novel, potent and orally effective cholecystokinin A antagonist, FK-480. Synthesis and structure-activity relationships of FK-480 and related compounds.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Cholecystokinin; Drug Evaluation; Drug Stability; Gastric Emptying; In Vitro Techniques; Indoles; Mice; Pancreas; Prodrugs; Rats; Sincalide; Structure-Activity Relationship | 1994 |
Characterization of a new cholecystokinin receptor antagonist FK480 in in vitro isolated rat pancreatic acini.
Topics: Animals; Benzodiazepinones; Devazepide; In Vitro Techniques; Indoles; Male; Pancreas; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide | 1994 |
Direct contractile effect of cholecystokinin octapeptide on caecal circular smooth muscle cells of guinea pig via both CCK-A and CCK-B/gastrin receptors.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Cecum; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1997 |