fr 109615 has been researched along with cycloleucine in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.65) | 18.7374 |
| 1990's | 14 (32.56) | 18.2507 |
| 2000's | 17 (39.53) | 29.6817 |
| 2010's | 9 (20.93) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Gordon, FJ; Pawloski-Dahm, C | 1 |
| Hu, GY; Storm, JF | 1 |
| Goodman, M; Pröbsti, A; Schiller, PW; Yamazaki, T | 1 |
| Inamoto, Y; Kamimura, T; Kawabata, K; Ohki, H; Sakane, K | 1 |
| Hashimoto, S; Inamoto, Y; Iwamoto, T; Kawabata, K; Sakane, K | 1 |
| Ezaki, M; Fujie, A; Hashimoto, S; Imanaka, H; Inamoto, Y; Iwamoto, T; Kawabata, K; Kohsaka, M; Okuhara, M; Tsujii, E | 1 |
| Goodman, M; Mierke, DF; Nössner, G; Schiller, PW | 1 |
| Kawaguchi, H; Konishi, M; Miyaki, T; Nishio, M; Oki, T; Saitoh, K | 1 |
| Hirano, M; Kamei, H; Numata, K; Oki, T; Tomatsu, K | 1 |
| Capobianco, JO; Coen, ML; Goldman, RC; Zakula, D | 1 |
| H Fer, M; Jethwaney, D; Khaware, RK; Prasad, R | 1 |
| Appella, DH; Barchi, JJ; Christianson, LA; Gellman, SH; Huang, X; Klein, DA; Powell, DR | 1 |
| Beattie, B; Blasberg, R; Finn, R; Joshi, R; Miyagawa, T; Oku, T; Tjuvajev, J; Uehara, H | 1 |
| Boje, KM; Lakhman, SS | 1 |
| Becker, J; Li, Z; Noe, CR | 1 |
| Danysz, W; Karcz-Kubicha, M; Wedzony, K; Zajaczkowski, W | 1 |
| Gellman, SH; Lee, HS; LePlae, PR; Umezawa, N | 1 |
| Aggarwal, VK; Alexander, R; Barrell, JK; Roseblade, SJ | 1 |
| Gellman, SH; Porter, EA; Weisblum, B | 1 |
| Bats, JW; Kählig, H; Langer, O; Mulzer, J; Zierler-Gould, K | 1 |
| Gellman, SH; Kim, BM; Lai, JR; Lee, HS; Park, JS | 1 |
| Aggarwal, VK; Alexander, R; Roseblade, S | 1 |
| Deng, W; Li, X; Liao, X; Tian, G; Yang, Z; Yi, J | 1 |
| Bunnage, ME; Davies, SG; Parkin, RM; Roberts, PM; Smith, AD; Withey, JM | 1 |
| Davies, SG; Garner, AC; Long, MJ; Smith, AD; Sweet, MJ; Withey, JM | 1 |
| Dumić, M; Hahn, MG; Kuhl, A; Mittendorf, J | 1 |
| Forró, E; Fülöp, F; Fülöp, L; Hollósi, M; Mándity, IM; Martinek, TA; Tóth, GK; Vass, E | 1 |
| D Kimpe, N; Mangelinckx, S | 1 |
| Shao, LC; Sheng, CQ; Zhang, WN | 1 |
| Cui, Q; Gellman, SH; Koenig, P; Yethiraj, A; Zhu, X | 1 |
| Aye, Y; Davies, SG; Garner, AC; Roberts, PM; Smith, AD; Thomson, JE | 1 |
| Hermans, JJ; Hop, WC; Incrocci, L; Jeekel, J; Kazemier, G; Morak, MJ; van Dekken, H; van der Gaast, A; van Eijck, CH | 1 |
| Forró, E | 1 |
| Forró, E; Fülöp, F; Hyyryläinen, AR; Pakarinen, JM; Vainiotalo, P | 1 |
| Gaus, K; Hollósi, M; Jewgiński, M; Majer, Z; Mándity, IM; Royo, S; Sewald, N; Strijowski, U; Szilvágyi, G; Vass, E; Wollschläger, K | 1 |
| Fülöp, F; Hänninen, MM; Kiss, L; Nonn, M; Sillanpää, R | 1 |
| Cherepanova, M; Forró, E; Fülöp, F; Kiss, L | 1 |
| Fülöp, F; Kiss, L; Mándity, IM; Ötvös, SB | 1 |
| Agneeswari, R; Fülöp, F; Gecse, Z; Grecsó, N; Hyun, MH; Ilisz, I; Nonn, M; Péter, A | 1 |
| Abate-Shen, C; Benson, M; Delto, JC; Kobayashi, T; McKiernan, J | 1 |
| Forest, KT; Gellman, SH; Guzei, IA; Kreitler, DF; Mortenson, DE; Thomas, NC | 1 |
| Ma, S; Wang, DH; Zhong, B | 1 |
| Martynow, D; Milewska, MJ; Milewski, S; Skwarecki, AS | 1 |
2 review(s) available for fr 109615 and cycloleucine
| Article | Year |
|---|---|
Alicyclic beta-amino acids in Medicinal Chemistry.
Topics: Amino Acids, Cyclic; Antifungal Agents; Central Nervous System Agents; Cycloleucine; Dopamine Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship | 2005 |
[Recent advances in the study of antifungal lead compounds with new chemical scaffolds].
Topics: 4-Butyrolactone; Animals; Antifungal Agents; Berberine; Cholestanols; Cycloleucine; Fungi; Heterocyclic Compounds; Humans; Lactones; Molecular Structure; Naphthoquinones; Pyridines; Structure-Activity Relationship | 2007 |
1 trial(s) available for fr 109615 and cycloleucine
| Article | Year |
|---|---|
Adjuvant intra-arterial chemotherapy and radiotherapy versus surgery alone in resectable pancreatic and periampullary cancer: a prospective randomized controlled trial.
Topics: Adenocarcinoma; Adult; Aged; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Common Bile Duct Neoplasms; Cycloleucine; Disease Progression; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Lead; Male; Middle Aged; Mitoxantrone; Pancreatic Neoplasms; Prognosis; Prospective Studies; Radiotherapy, Adjuvant; Sulfides; Treatment Outcome | 2008 |
40 other study(ies) available for fr 109615 and cycloleucine
| Article | Year |
|---|---|
Evidence for a kynurenate-insensitive glutamate receptor in nucleus tractus solitarii.
Topics: Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aorta; Blood Pressure; Cycloleucine; Electric Stimulation; Female; Heart Rate; Ibotenic Acid; Kynurenic Acid; Medulla Oblongata; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, Neurotransmitter | 1992 |
Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Neurons; Phorbol Esters; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Biological and conformational studies of [Val4]morphiceptin and [D-Val4]morphiceptin analogs incorporating cis-2-aminocyclopentane carboxylic acid as a peptidomimetic for proline.
Topics: Amino Acid Sequence; Computer Simulation; Cycloleucine; Endorphins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Proline; Protein Conformation; Spectrum Analysis; Structure-Activity Relationship; Temperature; Thermodynamics | 1991 |
Synthesis and antifungal activity of FR109615 analogs.
Topics: Antifungal Agents; Candida; Candida albicans; Cycloleucine | 1991 |
Synthesis and structure determination of FR109615, a new antifungal antibiotic.
Topics: Antifungal Agents; Candida; Candida albicans; Chromatography, High Pressure Liquid; Cycloleucine; Isomerism; Molecular Conformation; Molecular Structure; Streptomyces; X-Ray Diffraction | 1990 |
FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.
Topics: Animals; Antifungal Agents; Candida; Candidiasis; Cycloleucine; Female; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Molecular Structure; Spectrophotometry, Infrared; Streptomyces | 1990 |
Morphiceptin analogs containing 2-aminocyclopentane carboxylic acid as a peptidomimetic for proline.
Topics: Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Computer Simulation; Cycloleucine; Endorphins; Magnetic Resonance Spectroscopy; Mice; Models, Biological; Molecular Sequence Data; Proline; Protein Conformation; Structure-Activity Relationship | 1990 |
Cispentacin, a new antifungal antibiotic. I. Production, isolation, physico-chemical properties and structure.
Topics: Antifungal Agents; Bacillus cereus; Candida albicans; Chemical Phenomena; Chemistry; Cycloleucine; Fermentation | 1989 |
Cispentacin, a new antifungal antibiotic. II. In vitro and in vivo antifungal activities.
Topics: Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis; Cycloleucine; Drug Evaluation, Preclinical; Flucytosine; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests | 1989 |
Anti-Candida activity of cispentacin: the active transport by amino acid permeases and possible mechanisms of action.
Topics: Amino Acid Transport Systems; Amino Acyl-tRNA Synthetases; Antifungal Agents; Biological Transport, Active; Candida albicans; Cycloleucine; Kinetics; Membrane Transport Proteins; RNA, Transfer | 1993 |
Functional reconstitution of a purified proline permease from Candida albicans: interaction with the antifungal cispentacin.
Topics: Amino Acid Transport Systems, Neutral; Antifungal Agents; Biological Transport; Candida albicans; Chromatography, Affinity; Cycloleucine; Ethylmaleimide; Ionophores; Kinetics; Membrane Potentials; Membrane Transport Modulators; Membrane Transport Proteins; Proline; Proteolipids; Solubility; Valinomycin | 1997 |
Residue-based control of helix shape in beta-peptide oligomers.
Topics: Amino Acids; Circular Dichroism; Cyclohexanecarboxylic Acids; Cyclohexylamines; Cycloleucine; Magnetic Resonance Spectroscopy; Models, Molecular; Oligopeptides; Protein Folding; Protein Structure, Secondary | 1997 |
Imaging experimental brain tumors with 1-aminocyclopentane carboxylic acid and alpha-aminoisobutyric acid: comparison to fluorodeoxyglucose and diethylenetriaminepentaacetic acid in morphologically defined tumor regions.
Topics: Aminoisobutyric Acids; Animals; Autoradiography; Brain Neoplasms; Cycloleucine; Fluorodeoxyglucose F18; Humans; Male; Neoplasm Transplantation; Pentetic Acid; Radiopharmaceuticals; Rats; Rats, Inbred F344; Rats, Inbred WF; Rats, Sprague-Dawley; Time Factors; Tumor Cells, Cultured | 1997 |
Chronic dosing with 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, modulates NMDA inhibition of muscarinic-coupled PI hydrolysis in rat cortical slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; In Vitro Techniques; Inositol; Kynurenic Acid; Male; Muscarinic Agonists; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1998 |
Molecular and pharmacological characterization of recombinant rat/mice N-methyl-D-aspartate receptor subtypes in the yeast Saccharomyces cerevisiae.
Topics: Animals; Carbodiimides; Cell Membrane; Cloning, Molecular; Cycloleucine; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression; Glutamic Acid; Indoles; Kynurenic Acid; Mice; Microscopy, Fluorescence; Protein Binding; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Transformation, Genetic | 1998 |
NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Antimetabolites; Antipsychotic Agents; Binding Sites; Cycloleucine; Cycloserine; Disease Models, Animal; Dopamine Agents; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hallucinogens; Locomotion; Male; Phencyclidine; Phthalazines; Protein Structure, Tertiary; Psychotic Disorders; Pyrrolidinones; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 1999 |
An efficient route to either enantiomer of trans-2-aminocyclopentanecarboxylic acid.
Topics: Cycloleucine; Molecular Conformation; Oligopeptides; Protein Structure, Secondary | 2001 |
Highly diastereoselective nitrone cycloaddition onto a chiral ketene equivalent: asymmetric synthesis of cispentacin.
Topics: Antifungal Agents; Bridged-Ring Compounds; Catalysis; Cycloleucine; Indicators and Reagents; Oxidation-Reduction; Spiro Compounds; Stereoisomerism | 2002 |
Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacillus subtilis; Cycloleucine; Drug Stability; Endopeptidases; Enterococcus faecium; Escherichia coli; Humans; Magainins; Microbial Sensitivity Tests; Molecular Mimicry; Molecular Sequence Data; Oligopeptides; Protein Structure, Secondary; Staphylococcus aureus; Structure-Activity Relationship; Xenopus Proteins | 2002 |
A bicyclic cispentacin derivative as a novel reverse turn inducer in a GnRH mimetic.
Topics: Amino Acid Sequence; Amino Acids; Bridged Bicyclo Compounds; Crystallography, X-Ray; Cycloleucine; Gonadotropin-Releasing Hormone; Humans; Magnetic Resonance Spectroscopy; Molecular Mimicry; Molecular Structure; Protein Conformation; Receptors, LHRH; Structure-Activity Relationship | 2002 |
Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold.
Topics: Circular Dichroism; Cycloleucine; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Protein Structure, Secondary | 2003 |
The use of enantiomerically pure ketene dithioacetal bis(sulfoxides) in highly diastereoselective intramolecular nitrone cycloadditions. Application in the total synthesis of the beta-amino acid (-)-cispentacin and the first asymmetric synthesis of cis-(3
Topics: Antifungal Agents; Carboxylic Acids; Cycloleucine; Nitrogen Oxides; Pyrrolidines; Stereoisomerism; Sulfoxides | 2003 |
Expression of angiogenic factors in hepatocellular carcinoma after transcatheter arterial chemoembolization.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Catheterization, Peripheral; Chemoembolization, Therapeutic; Cycloleucine; Female; Fibroblast Growth Factor 2; Fluorouracil; Humans; Liver Neoplasms; Middle Aged; Mitomycin; Vascular Endothelial Growth Factor A | 2003 |
Kinetic resolution of tert-butyl (RS)-3-alkylcyclopentene-1-carboxylates for the synthesis of homochiral 3-alkyl-cispentacin and 3-alkyl-transpentacin derivatives.
Topics: Amides; Carboxylic Acids; Chemistry, Organic; Cycloleucine; Kinetics; Lithium Compounds; Molecular Mimicry; Pentetic Acid; Stereoisomerism | 2004 |
Parallel kinetic resolution of tert-butyl (RS)-3-alkyl-cyclopentene-1-carboxylates for the asymmetric synthesis of 3-alkyl-cispentacin derivatives.
Topics: Amides; Chemistry, Organic; Cycloleucine; Kinetics; Lithium Compounds; Stereoisomerism | 2004 |
Effects of the alternating backbone configuration on the secondary structure and self-assembly of beta-peptides.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Circular Dichroism; Cycloleucine; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Peptides; Protein Structure, Secondary; Solutions; Stereoisomerism | 2006 |
Beta-azidocyclopropanediesters: useful building blocks with potential application in agricultural and pharmaceutical chemistry.
Topics: Agriculture; Amino Acids, Cyclic; Chemistry, Pharmaceutical; Cycloleucine; Protein Structure, Secondary | 2006 |
Establishing effective simulation protocols for beta- and alpha/beta-peptides. II. Molecular mechanical (MM) model for a cyclic beta-residue.
Topics: Algorithms; Amino Acids; Computer Simulation; Cyclization; Cycloleucine; Models, Chemical; Molecular Structure; Peptides; Protein Structure, Secondary | 2008 |
Parallel kinetic resolution of tert-butyl (RS)-3-oxy-substituted cyclopent-1-ene-carboxylates for the asymmetric synthesis of 3-oxy-substituted cispentacin and transpentacin derivatives.
Topics: Carboxylic Acids; Cycloleucine; Kinetics; Models, Molecular | 2008 |
New gas chromatographic method for the enantioseparation of beta-amino acids by a rapid double derivatization technique.
Topics: Amino Acids, Cyclic; Chromatography, Gas; Cyclodextrins; Cycloleucine; Organic Chemicals; Reproducibility of Results; Sensitivity and Specificity; Siloxanes; Stereoisomerism | 2009 |
Chiral differentiation of some cyclic beta-amino acids by kinetic and fixed ligand methods.
Topics: Amino Acids, Cyclic; Copper; Cyclohexanecarboxylic Acids; Cyclohexylamines; Cycloleucine; Kinetics; Ligands; Nickel; Stereoisomerism | 2010 |
VCD studies on cyclic peptides assembled from L-α-amino acids and a trans-2-aminocyclopentane- or trans-2-aminocyclohexane carboxylic acid.
Topics: Circular Dichroism; Cyclohexanecarboxylic Acids; Cyclohexylamines; Cycloleucine; Molecular Conformation; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Peptidomimetics | 2010 |
Synthesis of highly functionalized fluorinated cispentacin derivatives.
Topics: beta-Lactams; Cyclization; Cycloleucine; Halogenation; Nitriles; Oxides | 2012 |
A new access route to functionalized cispentacins from norbornene β-amino acids.
Topics: Aldehydes; Amino Acids; beta-Lactams; Cycloleucine; Enzymes; Norbornanes; Oxidation-Reduction; Stereoisomerism | 2013 |
Alkyne-azide cycloadditions with copper powder in a high-pressure continuous-flow reactor: high-temperature conditions versus the role of additives.
Topics: Alkynes; Antifungal Agents; Azides; Catalysis; Copper; Cycloaddition Reaction; Cycloleucine; Hot Temperature; Isomerism; Pressure; Triazoles | 2013 |
High-performance liquid chromatographic enantioseparation of isoxazoline-fused 2-aminocyclopentanecarboxylic acids on a chiral ligand-exchange stationary phase.
Topics: Chromatography, High Pressure Liquid; Cycloleucine; Isoxazoles; Ligands; Stereoisomerism; Thermodynamics | 2013 |
Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression.
Topics: Administration, Intravesical; Animals; Antineoplastic Agents; Cycloleucine; Deoxycytidine; Disease Models, Animal; Disease Progression; Docetaxel; Drug Screening Assays, Antitumor; Female; Gemcitabine; Mice; Mice, Inbred C57BL; Random Allocation; Taxoids; Treatment Outcome; Urinary Bladder Neoplasms | 2013 |
Evaluation of β-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.
Topics: Amino Acids; Cycloleucine; Models, Molecular; Molecular Structure; Protein Stability; Proteins; Temperature | 2018 |
Ablation of TRPV1 Elevates Nocturnal Blood Pressure in Western Diet-fed Mice.
Topics: Animals; Blood Pressure; Circadian Rhythm; Cycloleucine; Diet, Western; Disease Models, Animal; Gene Expression Regulation; Hypertension; Male; Mice; Mice, Knockout; Sympathetic Nervous System; TRPV Cation Channels | 2019 |
Molecular Umbrella as a Nanocarrier for Antifungals.
Topics: Antifungal Agents; Candida albicans; Candida glabrata; Cholic Acid; Cycloleucine; Drug Carriers; Erythrocytes; Hemolytic Agents; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2021 |