Page last updated: 2024-09-03

foy 251 and camostat

foy 251 has been researched along with camostat in 8 studies

Compound Research Comparison

Studies
(foy 251)
Trials
(foy 251)
Recent Studies (post-2010)
(foy 251)
Studies
(camostat)
Trials
(camostat)
Recent Studies (post-2010) (camostat)
9023371493

Protein Interaction Comparison

ProteinTaxonomyfoy 251 (IC50)camostat (IC50)
Transmembrane protease serine 2Homo sapiens (human)0.018
ProthrombinHomo sapiens (human)0.399
Serine protease hepsinHomo sapiens (human)0.0235
Trypsin-1Homo sapiens (human)0.0035
Trypsin-2Homo sapiens (human)0.0035
Procathepsin LHomo sapiens (human)0.018
FurinHomo sapiens (human)0.018
Trypsin-3Homo sapiens (human)0.0035
Transmembrane protease serine 6Homo sapiens (human)0.018
Multidrug and toxin extrusion protein 1Homo sapiens (human)2.9

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Ito, H; Kamiyasu, K; Kato, M; Maruyama, T; Miyazaki, T; Nakai, H; Nakayama, Y; Odagaki, Y; Sakaki, K; Senokuchi, K1
Fuji, M; Fujisawa, T; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Arnold, R; Beckh, K; Göke, B; Müller, R1
Yonezawa, H1
Bonn, R; Brindley, CJ; Chasseaud, LF; Cheng, KN; Hood, AJ; Irons, SR; Midgley, I; Proctor, P1
Adachi, M; Kakizoe, Y; Kitamura, K; Ko, T; Maekawa, A; Miyoshi, T; Shiraishi, N; Tomita, K; Wakida, N1
Chen, J; Guo, H; Huang, Y; Liu, C; Shan, W; Xiao, Z1
Bajraktari-Sylejmani, G; Haefeli, WE; Weiss, J1

Other Studies

8 other study(ies) available for foy 251 and camostat

ArticleYear
New orally active serine protease inhibitors.
    Journal of medicinal chemistry, 1995, Jul-07, Volume: 38, Issue:14

    Topics: Administration, Oral; Amino Acid Sequence; Animals; Benzamidines; Dogs; Molecular Sequence Data; Rats; Serine Proteinase Inhibitors

1995
Beneficial effects of the synthetic trypsin inhibitor camostate in cerulein-induced acute pancreatitis in rats.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:2

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Esters; Gabexate; Guanidines; Male; Organ Size; Pancreas; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Secretin; Trypsin Inhibitors

1990
Elimination of the low-molecular weight proteinase inhibitor camostate (FOY 305) and its degradation products by the rat liver.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1987, Volume: 187, Issue:6

    Topics: Administration, Oral; Animals; Benzoates; Biotransformation; Esters; Female; Gabexate; Guanidines; In Vitro Techniques; Liver; Perfusion; Protease Inhibitors; Rats; Rats, Inbred Strains

1987
Discrepancy between the potency of various trypsin inhibitors to inhibit trypsin activity and the potency to release biologically active cholecystokinin-pancreozymin.
    The Japanese journal of physiology, 1984, Volume: 34, Issue:5

    Topics: Animals; Benzamidines; Cholecystokinin; Duodenum; Esters; Gabexate; Guanidines; Male; Pancreas; Rats; Rats, Inbred Strains; Stimulation, Chemical; Trypsin Inhibitors

1984
Metabolic fate of 14C-camostat mesylate in man, rat and dog after intravenous administration.
    Xenobiotica; the fate of foreign compounds in biological systems, 1994, Volume: 24, Issue:1

    Topics: Adult; Animals; Benzoates; Biotransformation; Blood Proteins; Carbon Radioisotopes; Dogs; Esters; Gabexate; Guanidines; Humans; Infusions, Intravenous; Male; Protease Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Tissue Distribution; Trypsin Inhibitors

1994
Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.
    Journal of hypertension, 2009, Volume: 27, Issue:1

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Cells, Cultured; Esters; Gabexate; Guanidines; Hypertension; Kidney; Mice; Rats; Rats, Inbred Dahl; RNA, Small Interfering; Serine Endopeptidases; Serine Proteinase Inhibitors

2009
Enhanced stability of oral insulin in targeted peptide ligand trimethyl chitosan nanoparticles against trypsin.
    Journal of microencapsulation, 2015, Volume: 32, Issue:7

    Topics: Administration, Oral; Chitosan; Drug Carriers; Drug Delivery Systems; Endocytosis; Esters; Gabexate; Guanidines; Insulin; Intestinal Mucosa; Ligands; Nanoparticles; Polyglutamic Acid; Trypsin; Trypsin Inhibitors

2015
Low risk of the TMPRSS2 inhibitor camostat mesylate and its metabolite GBPA to act as perpetrators of drug-drug interactions.
    Chemico-biological interactions, 2021, Apr-01, Volume: 338

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Drug Interactions; Esters; Guanidines; Humans; Organic Anion Transporters; Pregnane X Receptor; Receptors, Aryl Hydrocarbon; RNA, Messenger; Serine Endopeptidases; Serine Proteinase Inhibitors

2021