fostriecin and beta-isocupreidine

fostriecin has been researched along with beta-isocupreidine* in 1 studies

Other Studies

1 other study(ies) available for fostriecin and beta-isocupreidine

ArticleYear
Enantio- and stereoselective route to the phoslactomycin family of antibiotics: formal synthesis of (+)-fostriecin and (+)-phoslactomycin B.
    Chemical communications (Cambridge, England), 2009, Oct-21, Issue:39

    A general methodology applicable for the synthesis of the phoslactomycin family of antibiotics, potent and selective protein phosphatase inhibitors, has been developed starting from a beta-isocupreidine-catalyzed asymmetric Baylis-Hillman reaction of 3-(4-methoxybenzyloxy)propanal with hexafluoroisopropyl acrylate, and thereby formal syntheses of (+)-fostriecin and (+)-phoslactomycin B have been accomplished.

    Topics: Alkenes; Anti-Bacterial Agents; Catalysis; Enzyme Inhibitors; Hydroxyquinolines; Lactones; Organophosphorus Compounds; Polyenes; Protein Phosphatase 1; Pyrones; Quinuclidines; Stereoisomerism

2009