fosfluconazole has been researched along with fluconazole in 20 studies
| Studies (fosfluconazole) | Trials (fosfluconazole) | Recent Studies (post-2010) (fosfluconazole) | Studies (fluconazole) | Trials (fluconazole) | Recent Studies (post-2010) (fluconazole) |
|---|---|---|---|---|---|
| 23 | 6 | 6 | 9,343 | 721 | 3,664 |
| Protein | Taxonomy | fosfluconazole (IC50) | fluconazole (IC50) |
|---|---|---|---|
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | 0.1296 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 9.21 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (80.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Sekiguchi, K; Shimatani, K; Sobue, S; Tan, K | 1 |
| Hust, R; Layton, G; Shaw, L; Sobue, S; Tan, K | 1 |
| Layton, G; Leclerc, V; Sobue, S; Tan, K; Weil, A | 1 |
| Eve, M; Layton, G; Sanderson, JB; Sobue, S; Tan, K | 1 |
| Abe, M; Ishiko, J; Kawakami, Y; Nagino, K; Shinkai, K; Sobue, S | 1 |
| Hasegawa, T; Higano, S; Itoyama, Y; Kikuchi, T; Miyoshi, T; Nakashima, I; Shiga, Y; Tago, H | 1 |
| Haug-Pihale, G; Sobue, S; Tan, K | 1 |
| Aoyama, T; Hatta, S; Kimura, K; Masuhara, K; Matsumoto, Y; Ogata, K; Shima, Y; Shimizu, M | 1 |
| Fujinaga, H; Oda, S; Takahashi, K | 1 |
| Hino, M; Ichihara, H; Kanashima, H; Koh, H; Koh, KR; Nakamae, H; Nakane, T; Sakamoto, E; Takeoka, Y; Yamane, T | 1 |
| Iishii, K; Inami, N; Kimura, E; Nomura, S; Urase, F | 1 |
| Hisatake, J; Shimozuma, J | 1 |
| Fujii, Y; Inase, N; Yoshizawa, Y | 1 |
| Lai, Y; Li, N; Yuan, H | 1 |
| Higuchi, B; Hirano, S; Inoue, M; Ishihara, T; Kawa, K; Kondo, O; Kouroki, M; Koyama, M; Sakata, A; Sakata, N; Sawada, A; Takeshita, Y; Yasui, M; Yoshioka, A | 1 |
| Aoyama, T; Hayashi, H; Hirata, K; Hirata, R; Matsumoto, Y; Yamamoto, Y; Yamazaki, H | 1 |
| Niki, Y; Ohbayashi, H; Shoji, H; Takuma, T; Yamamoto, T; Yoshida, K | 1 |
| Hagiya, H; Kajioka, H | 1 |
| Asano, Y; Ishida, K; Kosugi, H; Mochizuki, K; Murata, K; Yamada, H; Yamada, W | 1 |
2 review(s) available for fosfluconazole and fluconazole
| Article | Year |
|---|---|
[Nonclinical studies and clinical studies on fosfluconazole, a triazole antifungal agent (Prodif)].
Topics: Adult; Animals; Antifungal Agents; Candidiasis; Clinical Trials as Topic; Cryptococcosis; Fluconazole; Humans; Injections, Intravenous; Male; Organophosphates; Rats | 2004 |
[Clinical efficacies of antifungal injections].
Topics: Amphotericin B; Antifungal Agents; Drug Delivery Systems; Echinocandins; Fluconazole; Humans; Infusions, Intravenous; Injections; Itraconazole; Lipopeptides; Liposomes; Micafungin; Mycoses; Organophosphates; Pyrimidines; Triazoles; Voriconazole | 2008 |
6 trial(s) available for fosfluconazole and fluconazole
| Article | Year |
|---|---|
Pharmacokinetics and safety of Fosfluconazole after single intravenous bolus injection in healthy male Japanese volunteers.
Topics: Adult; Antifungal Agents; Area Under Curve; Cohort Studies; Cross-Over Studies; Dose-Response Relationship, Drug; Electrocardiography; Fluconazole; Half-Life; Humans; Injections, Intravenous; Male; Organophosphates; Prodrugs; Single-Blind Method; Time Factors | 2004 |
Comparison of the pharmacokinetics of fosfluconazole and fluconazole after single intravenous administration of fosfluconazole in healthy Japanese and Caucasian volunteers.
Topics: Adult; Antifungal Agents; Area Under Curve; Asian People; Biological Availability; Cross-Over Studies; Double-Blind Method; Female; Fluconazole; Half-Life; Humans; Injections, Intravenous; Japan; Male; Metabolic Clearance Rate; Middle Aged; Organophosphates; White People | 2004 |
The effects of renal impairment on the pharmacokinetics and safety of fosfluconazole and fluconazole following a single intravenous bolus injection of fosfluconazole.
Topics: Adolescent; Adult; Antifungal Agents; Area Under Curve; Female; Fluconazole; Humans; Injections, Intravenous; Kidney Diseases; Male; Organophosphates | 2004 |
Pharmacokinetics of fosfluconazole and fluconazole following multiple intravenous administration of fosfluconazole in healthy male volunteers.
Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Double-Blind Method; Fluconazole; Humans; Infusions, Intravenous; Male; Organophosphates | 2004 |
The effects of hepatic impairment on the pharmacokinetics of fosfluconazole and fluconazole following a single intravenous bolus injection of fosfluconazole.
Topics: Adult; Antifungal Agents; Female; Fluconazole; Humans; Injections, Intravenous; Liver Diseases; Male; Middle Aged; Organophosphates; Prodrugs | 2005 |
[Comparison of micafungin and fosfluconazole as prophylaxis for invasive fungal infection during neutropenia in children undergoing chemotherapy and hematopoietic stem cell transplantation].
Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Echinocandins; Female; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Infant; Lipopeptides; Male; Meropenem; Micafungin; Minocycline; Mycoses; Neutropenia; Opportunistic Infections; Organophosphates; Prodrugs; Thienamycins | 2009 |
12 other study(ies) available for fosfluconazole and fluconazole
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
[A case of cryptococcal meningitis presenting initially as bilateral hearing loss].
Topics: Antifungal Agents; Fluconazole; Gadolinium; Hearing Loss, Bilateral; Humans; Magnetic Resonance Imaging; Male; Meningitis, Cryptococcal; Middle Aged; Organophosphates | 2004 |
Pharmacokinetics of fluconazole and fosfluconazole after intraperitoneal administration to peritoneal dialysis rats.
Topics: Acute Kidney Injury; Algorithms; Alkaline Phosphatase; Animals; Antifungal Agents; Area Under Curve; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Fluconazole; Injections, Intraperitoneal; Injections, Intravenous; Male; Organophosphates; Peritoneal Dialysis, Continuous Ambulatory; Rats; Rats, Wistar | 2005 |
Infectious myositis involving the piriformis in a patient with rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal; Antifungal Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Candidiasis; Drug Therapy, Combination; Female; Fluconazole; Humans; Infliximab; Methotrexate; Middle Aged; Muscle, Skeletal; Myositis; Organophosphates; Staphylococcal Infections; Tomography, X-Ray Computed | 2006 |
[Improved outcome in brain abscess during induction in acute myelocytic leukemia].
Topics: Adult; Antifungal Agents; Brain; Brain Abscess; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluconazole; Humans; Leukemia, Myeloid, Acute; Meropenem; Organophosphates; Peripheral Blood Stem Cell Transplantation; Positron-Emission Tomography; Thienamycins; Tomography, X-Ray Computed | 2007 |
Elevation of activated platelet-dependent chemokines and soluble cell adhesion molecules in patients with hematologic malignancies and high levels of beta-D-glucan.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; beta-Glucans; Biomarkers; Candidiasis; Cell Adhesion Molecules; Chemokines; Female; Fluconazole; Fungemia; Hematologic Neoplasms; Humans; Male; Middle Aged; Neutropenia; Organophosphates; Platelet Activation; Prodrugs | 2007 |
[Hypercalcemia associated with all-trans retinoic acid therapy for microgranular type acute promyelocytic leukemia].
Topics: Adult; Antineoplastic Agents; Drug Interactions; Drug Therapy, Combination; Fluconazole; Humans; Hypercalcemia; Leukemia, Promyelocytic, Acute; Male; Organophosphates; Tretinoin | 2008 |
Evaluation of in vitro models for screening alkaline phosphatase-mediated bioconversion of phosphate ester prodrugs.
Topics: Alkaline Phosphatase; Animals; Caco-2 Cells; Drug Delivery Systems; Drug Stability; Fluconazole; Half-Life; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestines; Male; Mucous Membrane; Organophosphates; Phenytoin; Phosphates; Prodrugs; Rats; Rats, Sprague-Dawley; Solubility | 2009 |
Population pharmacokinetics of fluconazole after administration of fosfluconazole and fluconazole in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Computer Simulation; Critical Care; Female; Fluconazole; Half-Life; Humans; Injections, Intravenous; Japan; Metabolic Clearance Rate; Middle Aged; Models, Biological; Monte Carlo Method; Mycoses; Organophosphates; Prodrugs; Young Adult | 2012 |
Measurement of antifungal drug levels in cerebrospinal fluid for cryptococcal meningoencephalitis.
Topics: Aged; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Fluconazole; Humans; Male; Meningitis, Cryptococcal; Meningoencephalitis; Microbial Sensitivity Tests; Organophosphates; Pyrimidines; Triazoles; Voriconazole | 2012 |
Successful treatment of recurrent candidemia due to candidal thrombophlebitis associated with a central venous catheter using a combination of fosfluconazole and micafungin.
Topics: Aged, 80 and over; Antifungal Agents; Candidemia; Catheter-Related Infections; Central Venous Catheters; Drug Therapy, Combination; Echinocandins; Female; Fluconazole; Humans; Jugular Veins; Lipopeptides; Micafungin; Organophosphates; Recurrence; Thrombophlebitis; Tomography, X-Ray Computed; Ultrasonography, Doppler, Color | 2013 |
Case of cryptococcal choroiditis in adult with T-cell leukemia/lymphoma.
Topics: Aged; Amphotericin B; Antifungal Agents; Choroiditis; Cryptococcosis; Cryptococcus neoformans; Eye; Eye Infections, Fungal; Fatal Outcome; Female; Fluconazole; Humans; Intravitreal Injections; Leukemia-Lymphoma, Adult T-Cell; Multifocal Choroiditis; Organophosphates; Tomography, Optical Coherence | 2019 |