foscarnet and zalcitabine

foscarnet has been researched along with zalcitabine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's13 (50.00)18.2507
2000's6 (23.08)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corbett, TH; Court, BA; Kessel, D; Phadtare, S; Renis, HE; Zimlicka, J1
De Clercq, E1
Cha, SH; Endou, H; Kanai, Y; Kimura, M; Sekine, T; Tsuda, M; Wada, S1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Ayisi, NK; Gupta, SV; Qualtiere, LF1
Cersosimo, RJ; Matthews, SJ; Spivack, ML1
Cotton, P1
Darby, G; Larder, BA; Richman, DD1
Richman, DD1
Caliendo, AM; Hirsch, MS1
Berthillon, P; Camplo, M; Charvet, AS; Chermann, JC; Faury, P; Graciet, JC; Hantz, O; Mourier, N; Trépo, C; Turin, F1
Morris, DJ1
Gobert, JM; North, TW; Remington, KM; Zhu, YQ1
Camplo, M; Charvet, AS; Chermann, JC; Faury, P; Graciet, JC; Kraus, JL; Mourier, N1
Brun-Vezinet, F; Pépin, JM; Simon, F1
Anderson, KP; Azad, RF; Brown-Driver, V; Buckheit, RW1
Cox, S; Harmenberg, J; Palmer, S1
Fujiwara, T; Kaneko, H; Mori, S; Shigeta, S1
Mills, R; Wu, GZ1

Reviews

6 review(s) available for foscarnet and zalcitabine

ArticleYear
Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS).
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adsorption; Antibodies, Viral; Antigens, Viral; Aurintricarboxylic Acid; Deltaretrovirus; Deoxycytidine; Foscarnet; Genes, Viral; Glycoproteins; Humans; Interferons; Male; Phosphonoacetic Acid; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Viral; Suramin; Thymidine; Transcription, Genetic; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine

1986
Zidovudine and other reverse transcriptase inhibitors in the management of human immunodeficiency virus-related disease.
    Pharmacotherapy, 1991, Volume: 11, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Female; Foscarnet; HIV Infections; Humans; Phosphonoacetic Acid; Pregnancy; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1991
The treatment of HIV infection.
    AIDS (London, England), 1988, Volume: 2 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Evaluation; Foscarnet; Humans; Opportunistic Infections; Phosphonoacetic Acid; Zalcitabine; Zidovudine

1988
Combination therapy for infection due to human immunodeficiency virus type 1.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4

    Topics: Acyclovir; Antiviral Agents; CD4 Antigens; Clinical Trials as Topic; Combined Modality Therapy; Didanosine; Drug Therapy, Combination; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Interferon alpha-2; Interferon-alpha; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1994
Adverse effects and drug interactions of clinical importance with antiviral drugs.
    Drug safety, 1994, Volume: 10, Issue:4

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Amantadine; Antiviral Agents; Didanosine; Drug Interactions; Foscarnet; Ganciclovir; Humans; Interferon-alpha; Ribavirin; Rimantadine; Vidarabine; Zalcitabine; Zidovudine

1994
[Is resistance of human immunodeficiency viruses (HIV) to nucleoside analogs an indication for their combined use?].
    Pathologie-biologie, 1993, Volume: 41, Issue:8 Pt 2

    Topics: Acyclovir; Didanosine; Drug Synergism; Drug Therapy, Combination; Female; Foscarnet; HIV-1; Humans; In Vitro Techniques; Male; Ribavirin; Zalcitabine; Zidovudine

1993

Trials

1 trial(s) available for foscarnet and zalcitabine

ArticleYear
The treatment of HIV infection.
    AIDS (London, England), 1988, Volume: 2 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Evaluation; Foscarnet; Humans; Opportunistic Infections; Phosphonoacetic Acid; Zalcitabine; Zidovudine

1988

Other Studies

20 other study(ies) available for foscarnet and zalcitabine

ArticleYear
Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Friend murine leukemia virus; HIV-1; HIV-2; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides; Rauscher Virus; Structure-Activity Relationship

1991
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Acyclovir; Animals; Anion Transport Proteins; Antiviral Agents; Carrier Proteins; Didanosine; In Vitro Techniques; Lamivudine; Oocytes; Rats; Stavudine; Transfection; Trifluridine; Xenopus laevis; Zalcitabine; Zidovudine

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Modified tetrazolium-based colorimetric method for determining the activities of anti-HIV compounds.
    Journal of virological methods, 1991, Volume: 33, Issue:3

    Topics: Antiviral Agents; Cell Line; Colorimetry; Didanosine; Foscarnet; HIV-1; Humans; Phosphonoacetic Acid; Tetrazolium Salts; Thymidine; Zalcitabine; Zidovudine

1991
Wider access provided to AIDS drugs with actions against HIV, CMV infections.
    JAMA, 1990, Oct-17, Volume: 264, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; HIV Infections; Humans; Phosphonoacetic Acid; Zalcitabine

1990
HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy.
    Science (New York, N.Y.), 1989, Mar-31, Volume: 243, Issue:4899

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Dideoxynucleosides; Drug Resistance; Foscarnet; HeLa Cells; HIV; HIV Core Protein p24; Humans; Microbial Sensitivity Tests; Phosphonoacetic Acid; Retroviridae Proteins; Reverse Transcriptase Inhibitors; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1989
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine

1995
Synthesis and antiviral activity of new carbonylphosphonate 2',3'-dideoxy-3'-thiacytidine conjugates.
    Antiviral research, 1994, Volume: 25, Issue:2

    Topics: Animals; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Drug Evaluation, Preclinical; Ducks; Foscarnet; Giant Cells; Hepatitis B Virus, Duck; HIV-1; Humans; Lamivudine; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Structure-Activity Relationship; Thionucleosides; Zalcitabine

1994
Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'-deoxythymidine.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4

    Topics: Animals; Antiviral Agents; Cats; Cells, Cultured; Didanosine; Drug Resistance, Microbial; Foscarnet; Immunodeficiency Virus, Feline; Mutation; Phenotype; Zalcitabine; Zidovudine

1994
Inhibition of human immunodeficiency virus type 1 replication by phosphonoformate- and phosphonoacetate-2',3'-dideoxy-3'-thiacytidine conjugates.
    Journal of medicinal chemistry, 1994, Jul-08, Volume: 37, Issue:14

    Topics: Antiviral Agents; Foscarnet; HIV-1; Lamivudine; Phosphonoacetic Acid; Prodrugs; Structure-Activity Relationship; Virus Replication; Zalcitabine

1994
Antiviral activity of a phosphorothioate oligonucleotide complementary to human cytomegalovirus RNA when used in combination with antiviral nucleoside analogs.
    Antiviral research, 1995, Volume: 28, Issue:2

    Topics: Antiviral Agents; Base Sequence; Cell Line; Cytomegalovirus; Drug Interactions; Foscarnet; Ganciclovir; HIV-1; Humans; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; RNA, Viral; Thionucleotides; Virus Replication; Zalcitabine; Zidovudine

1995
Synergistic inhibition of human immunodeficiency virus isolates (including 3'-azido-3'-deoxythymidine-resistant isolates) by foscarnet in combination with 2',3'-dideoxyinosine or 2',3'-dideoxycytidine.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Antiviral Agents; Cells, Cultured; Didanosine; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Foscarnet; HIV-1; Humans; Microbial Sensitivity Tests; Monocytes; Zalcitabine; Zidovudine

1996
[Evaluation of antiviral agents for adenovirus using the MTT method in vitro].
    Nippon Ganka Gakkai zasshi, 2000, Volume: 104, Issue:11

    Topics: Acyclovir; Adenoviridae; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Foscarnet; Humans; Organophosphonates; Organophosphorus Compounds; Zalcitabine

2000
Synthesis and evaluation of novel prodrugs of foscarnet and dideoxycytidine with a universal carrier compound comprising a chemiluminescent and a photochromic conjugate.
    Journal of pharmaceutical sciences, 2004, Volume: 93, Issue:5

    Topics: Animals; Drug Carriers; Drug Evaluation, Preclinical; Foscarnet; HIV-1; Humans; Luminescent Agents; Macrophages; Mice; Prodrugs; Zalcitabine

2004