foscarnet and aphidicolin

foscarnet has been researched along with aphidicolin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brideau, RJ; Cudahy, MM; Homa, FL; Hopkins, TA; Knechtel, ML; Oien, NL; Pitts, TW; Poorman, RA; Schnute, ME; Wathen, MW; Wieber, JL1
Anderson, DJ; Brideau, RJ; Ciske, FL; Collier, SA; Cudahy, MM; Eggen, M; Genin, MJ; Hopkins, TA; Judge, TM; Kim, EJ; Knechtel, ML; Nair, SK; Nieman, JA; Oien, NL; Schnute, ME; Scott, A; Tanis, SP; Vaillancourt, VA; Wathen, MW; Wieber, JL1
Brideau, RJ; DiPaolo, BA; Hageman, MJ; Hopkins, TA; Knechtel, ML; Larsen, SD; Manninen, PR; Oien, NL; Rohrer, DC; Rush, BD; Schwende, FJ; Stefanski, KJ; Wathen, MW; Wieber, JL; Wilkinson, KF; Zamora, KM; Zhang, Z1
Brideau, RJ; Collier, SA; Cudahy, MM; Hopkins, TA; Knechtel, ML; Oien, NL; Sackett, RS; Schnute, ME; Scott, A; Stephan, ML; Wathen, MW; Wieber, JL1
Hopkins, TA; Knechtel, ML; Moon, MW; Oien, NL; Parker, TT; Perrault, WR; Stephanski, KJ; Strohbach, JW; Tanis, SP; Thaisrivongs, S; Wathen, MW; Wieber, JL1
Chen, K; Heasley, SE; Hopkins, TA; Knechtel, ML; Nair, SK; Nieman, JA; Nugent, RA; Oien, NL; Schultz, BL; Stephanski, KJ; Wathen, MW; Wieber, JL; Zerth, HM1
Birch, CJ; Doherty, RR; Gust, ID; Hayes, K; Tachedjian, G1
Carroll, RD; Haffey, ML; Matthews, JT; Stevens, JT1
Cheng, YC; Li, JS1
Allaudeen, HS1
Cheng, YC; Frank, KB1
Bornkamm, GW; Daillie, J; Decaussin, G; Lenoir, GM; Ooka, T1
Cox, GS; Park, KH1
Arens, M; Goto, Y; Hashimoto, T; Takahashi, T; Yamashita, T1
Bastow, KF; Cheng, YC; Derse, DD1
Larsson, A; Oberg, B; Wrååk, M1
Jeong, JH; Jung, G; Kwak, DS; Rho, HM1
Hwang, CB; Hwang, YT; Lu, Q; Zuccola, HJ1

Other Studies

18 other study(ies) available for foscarnet and aphidicolin

ArticleYear
4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Cytomegalovirus; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Nucleic Acid Synthesis Inhibitors; Point Mutation; Pyridines; Pyridones; Structure-Activity Relationship; Thiophenes; Viral Plaque Assay; Viral Proteins

2005
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.
    Bioorganic & medicinal chemistry letters, 2007, Jun-15, Volume: 17, Issue:12

    Topics: Antiviral Agents; Binding, Competitive; Cytomegalovirus; DNA-Directed DNA Polymerase; Enzyme Inhibitors; Ethylamines; Exodeoxyribonucleases; Herpes Zoster; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 4, Human; Humans; Models, Chemical; Nucleic Acid Synthesis Inhibitors; Pyridines; Structure-Activity Relationship; Viral Proteins

2007
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.
    Bioorganic & medicinal chemistry letters, 2007, Jul-15, Volume: 17, Issue:14

    Topics: Cytomegalovirus; Enzyme Inhibitors; Nucleic Acid Synthesis Inhibitors; Pyridines; Structure-Activity Relationship

2007
Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition.
    Bioorganic & medicinal chemistry letters, 2008, Jul-15, Volume: 18, Issue:14

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; Cytomegalovirus; Drug Design; Enzyme Inhibitors; Esters; Furans; Herpesviridae; Herpesvirus 3, Human; Herpesvirus 4, Human; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Nucleic Acid Synthesis Inhibitors; Pyridones; Simplexvirus

2008
The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase.
    Bioorganic & medicinal chemistry letters, 2010, Mar-15, Volume: 20, Issue:6

    Topics: Antiviral Agents; Drug Design; Protease Inhibitors; Quinoxalines; Serine Endopeptidases

2010
Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility.
    Bioorganic & medicinal chemistry letters, 2010, May-15, Volume: 20, Issue:10

    Topics: Antiviral Agents; Cytomegalovirus; DNA-Directed DNA Polymerase; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 3, Human; Humans; Nucleic Acid Synthesis Inhibitors; Pyrroles; Quinolines; Solubility; Structure-Activity Relationship

2010
Altered sensitivity to antiviral drugs of herpes simplex virus isolates from a patient with the acquired immunodeficiency syndrome.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Aphidicolin; Deoxyguanosine; Diterpenes; Drug Resistance, Microbial; Female; Foscarnet; Herpes Simplex; Humans; Phosphonoacetic Acid; Simplexvirus

1990
In vitro mutagenesis of the herpes simplex virus type 1 DNA polymerase gene results in altered drug sensitivity of the enzyme.
    Journal of virology, 1989, Volume: 63, Issue:11

    Topics: Amino Acid Sequence; Antiviral Agents; Aphidicolin; Asparagine; Base Sequence; Diterpenes; DNA-Directed DNA Polymerase; Foscarnet; Genes, Viral; Genetic Vectors; HeLa Cells; Humans; Kinetics; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Probes; Phosphonoacetic Acid; Saccharomyces cerevisiae; Serine; Simplexvirus; Viral Structural Proteins

1989
Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP.
    Virus genes, 1988, Volume: 1, Issue:4

    Topics: Aphidicolin; Deoxyribonucleotides; Diterpenes; Foscarnet; Guanine Nucleotides; Guanosine Monophosphate; Herpesvirus 4, Human; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Phosphonoacetic Acid; Protein Binding; Viral Proteins

1988
Distinctive properties of DNA polymerases induced by herpes simplex virus type-1 and Epstein-Barr virus.
    Antiviral research, 1985, Volume: 5, Issue:1

    Topics: Animals; Aphidicolin; Cell Line; Chromatography, DEAE-Cellulose; Diterpenes; DNA-Directed DNA Polymerase; Ethylmaleimide; Foscarnet; Herpesvirus 4, Human; Hot Temperature; Nucleic Acid Synthesis Inhibitors; Nucleosides; Phosphonoacetic Acid; Simplexvirus

1985
Mutually exclusive inhibition of herpesvirus DNA polymerase by aphidicolin, phosphonoformate, and acyclic nucleoside triphosphates.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:4

    Topics: Acyclovir; Antiviral Agents; Aphidicolin; Deoxyribonucleases; Diterpenes; Foscarnet; Guanosine Triphosphate; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Phosphonoacetic Acid; Simplexvirus

1985
Epstein-Barr virus-specific DNA polymerase in virus-nonproducer Raji cells.
    Journal of virology, 1986, Volume: 58, Issue:2

    Topics: Antigens, Viral; Aphidicolin; Butyrates; Butyric Acid; Cell Line; Diterpenes; DNA Replication; DNA-Directed DNA Polymerase; Enzyme Induction; Foscarnet; Herpesvirus 4, Human; Humans; Phosphonoacetic Acid; Substrate Specificity; Tetradecanoylphorbol Acetate; Virus Replication

1986
Induction of alkaline phosphatase and the glycoprotein hormone alpha subunit in HeLa cells by inhibitors of DNA polymerase.
    Archives of biochemistry and biophysics, 1982, Volume: 216, Issue:1

    Topics: Alkaline Phosphatase; Aphidicolin; Cycloheximide; Dactinomycin; Diterpenes; DNA Polymerase II; DNA Replication; Enzyme Induction; Foscarnet; Glycoprotein Hormones, alpha Subunit; Glycoproteins; HeLa Cells; Hormones; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Peptide Fragments; Phosphonoacetic Acid

1982
Characterization of hepatitis B virus DNA polymerase.
    Japanese journal of medical science & biology, 1984, Volume: 37, Issue:1

    Topics: Aphidicolin; Dideoxynucleotides; Diterpenes; DNA-Directed DNA Polymerase; Ethylmaleimide; Formaldehyde; Foscarnet; Hepatitis B virus; Hot Temperature; Nucleic Acid Synthesis Inhibitors; Phosphonoacetic Acid; Thymine Nucleotides; Vidarabine Phosphate; Virion

1984
Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:6

    Topics: Antiviral Agents; Aphidicolin; Arabinonucleosides; Coformycin; Diterpenes; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Pentostatin; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase; Vidarabine

1983
Effect of aphidicolin on DNA synthesis in HSV-1 infected and uninfected Vero cells.
    Antiviral research, 1983, Volume: 3, Issue:2

    Topics: Animals; Aphidicolin; Cell Line; Chlorocebus aethiops; Diterpenes; DNA; DNA, Viral; Foscarnet; Phosphonoacetic Acid; Simplexvirus

1983
The catalytic properties of human hepatitis B virus polymerase.
    Biochemical and biophysical research communications, 1996, Jun-14, Volume: 223, Issue:2

    Topics: Amino Acid Sequence; Aphidicolin; Binding Sites; Cations, Divalent; Chlorides; Conserved Sequence; Dactinomycin; DNA-Directed DNA Polymerase; Enzyme Inhibitors; Foscarnet; Hepatitis B virus; Humans; Kinetics; Magnesium Chloride; Manganese Compounds; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; RNA-Directed DNA Polymerase

1996
A point mutation within conserved region VI of herpes simplex virus type 1 DNA polymerase confers altered drug sensitivity and enhances replication fidelity.
    Journal of virology, 2004, Volume: 78, Issue:2

    Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Aphidicolin; Cell Line; Chlorocebus aethiops; Conserved Sequence; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Herpesvirus 1, Human; Microbial Sensitivity Tests; Molecular Sequence Data; Point Mutation; Sequence Alignment; Vero Cells; Viral Plaque Assay

2004