fosbretabulin has been researched along with calycopterin* in 1 studies
1 other study(ies) available for fosbretabulin and calycopterin
Article | Year |
---|---|
Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk.
Eighteen new analogues of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxy-flavone, a potent natural cytotoxic and antimitotic flavone, were synthesized from calycopterin, the major flavonoid of Calycopteris floribunda Lamk., a traditional Asian medicinal plant. One of them, the 3'-amino substituted analogue, displayed almost the same activity as the reference compound. Pharmacomodulation at C-3' on the B-ring, and at C-5,6,7 and 8 on the A-ring allowed to refine structure-activity relationships within the cytotoxic flavones series. Topics: Cell Line, Tumor; Cell Proliferation; Combretaceae; Flavones; Humans; Structure-Activity Relationship | 2011 |