| Protein | Taxonomy | fosamprenavir (IC50) | sildenafil (IC50) |
|---|
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | | 20 |
| Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 20 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | | 20 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | | 20 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | | 0.0024 |
| Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | | 0.0024 |
| Phosphodiesterase | Bos taurus (cattle) | | 9.2 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | | 2.881 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | Homo sapiens (human) | | 0.0187 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Rattus norvegicus (Norway rat) | | 0.0012 |
| High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | Homo sapiens (human) | | 2.881 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | | 0.2626 |
| High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | Homo sapiens (human) | | 4.2 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Canis lupus familiaris (dog) | | 0.0024 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Bos taurus (cattle) | | 0.0374 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | | 8.247 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | | 8.247 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | Bos taurus (cattle) | | 0.0545 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | | 0.78 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Rattus norvegicus (Norway rat) | | 4.6 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Rattus norvegicus (Norway rat) | | 4.6 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Rattus norvegicus (Norway rat) | | 4.6 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | Homo sapiens (human) | | 0.0187 |
| Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' | Bos taurus (cattle) | | 0.0366 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Homo sapiens (human) | | 0.0187 |
| Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Bos taurus (cattle) | | 0.0374 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | Bos taurus (cattle) | | 0.0374 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | | 7.9333 |
| Adenosine receptor A2a | Homo sapiens (human) | | 0.253 |
| Adenosine receptor A1 | Homo sapiens (human) | | 1.493 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | | 0.04 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | | 0.003 |
| Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | Homo sapiens (human) | | 0.0187 |
| Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' | Homo sapiens (human) | | 0.0418 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Rattus norvegicus (Norway rat) | | 4.6 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | | 0.7199 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Canis lupus familiaris (dog) | | 0.0182 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | | 0.78 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | | 1.8841 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Rattus norvegicus (Norway rat) | | 0.3 |
| Synaptic vesicular amine transporter | Rattus norvegicus (Norway rat) | | 0.01 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | | 6.3336 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4C | Homo sapiens (human) | | 8.52 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | | 5.7005 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | | 3.3075 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | | 4.7337 |
| High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | Homo sapiens (human) | | 4.69 |
| Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | Homo sapiens (human) | | 0.0187 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | | 0.7398 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | | 4.6677 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Bos taurus (cattle) | | 0.557 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Rattus norvegicus (Norway rat) | | 0.3 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | | 4.5 |
| Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | Bos taurus (cattle) | | 0.0374 |
| Phosphodiesterase | Rattus norvegicus (Norway rat) | | 0.3 |
| Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A | Homo sapiens (human) | | 4.1584 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 7B | Homo sapiens (human) | | 3.6006 |
| cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Homo sapiens (human) | | 4.2432 |