Page last updated: 2024-09-03

fosamprenavir and saquinavir

fosamprenavir has been researched along with saquinavir in 8 studies

Compound Research Comparison

Studies
(fosamprenavir)
Trials
(fosamprenavir)
Recent Studies (post-2010)
(fosamprenavir)
Studies
(saquinavir)
Trials
(saquinavir)
Recent Studies (post-2010) (saquinavir)
17455371,454256219

Protein Interaction Comparison

ProteinTaxonomyfosamprenavir (IC50)saquinavir (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.9
Bile salt export pumpHomo sapiens (human)3.9
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (BRU ISOLATE)0.016
Gag-Pol polyproteinHuman immunodeficiency virus type 2 (ISOLATE ROD)0.0084
Gag polyproteinHIV-1 M:B_MN0.0131
ATP-dependent translocase ABCB1Homo sapiens (human)4.05
Cytochrome P450 3A4Homo sapiens (human)1.5
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.0066
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4.273
Substance-K receptorHomo sapiens (human)6.214
Thromboxane-A synthase Homo sapiens (human)2.182
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)4.273
Mu-type opioid receptorHomo sapiens (human)9.625
Kappa-type opioid receptorHomo sapiens (human)6.951
Exoribonuclease H Human immunodeficiency virus 20.0005
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.9
Genome polyprotein Human rhinovirus sp.0.0005
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)8.26
Protease Human immunodeficiency virus 10.0217
Protease Human immunodeficiency virus 10.0004

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babusis, D; Bhoopathy, S; Hidalgo, IJ; Phan, TK; Ray, AS; Rhodes, GR; Robinson, KL; Strab, R; Tong, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
DeGoey, DA; Randolph, JT1
Back, D; Boffito, M; Dickinson, L; Fletcher, C; Gazzard, B; Higgs, C; Hill, A; Moyle, G; Nelson, M; Pozniak, A1
Adams, E; Hoogmartens, J; Van Schepdael, A; Yekkala, R1
Fessel, WJ; Hellinger, J; Kaufman, D; Rhee, SY; Ruane, P; Shafer, RW; Shirvani, V; Taylor, J; Towner, W; Troia, P; Zolopa, A1
Bogner, JR; Gyalrong-Steur, M; Seybold, U1

Reviews

3 review(s) available for fosamprenavir and saquinavir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Peptidomimetic inhibitors of HIV protease.
    Current topics in medicinal chemistry, 2004, Volume: 4, Issue:10

    Topics: Anti-HIV Agents; Atazanavir Sulfate; Carbamates; Clinical Trials as Topic; Dipeptides; Furans; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lopinavir; Models, Molecular; Molecular Mimicry; Molecular Structure; Nelfinavir; Oligopeptides; Organophosphates; Peptides; Phenylbutyrates; Pyridines; Pyrimidinones; Ritonavir; Saquinavir; Sulfonamides; Urethane

2004
Quality control of protease inhibitors.
    Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:6

    Topics: Anti-HIV Agents; Atazanavir Sulfate; Carbamates; Chromatography, Liquid; Darunavir; Drug Contamination; Furans; HIV Protease Inhibitors; Indinavir; Lopinavir; Nelfinavir; Oligopeptides; Organophosphates; Pyridines; Pyrimidinones; Pyrones; Quality Control; Ritonavir; Saquinavir; Sulfonamides

2008

Other Studies

5 other study(ies) available for fosamprenavir and saquinavir

ArticleYear
Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Adenine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; HIV Protease Inhibitors; Humans; Hydrolysis; Indicators and Reagents; Intestinal Absorption; Mass Spectrometry; Organophosphonates; Subcellular Fractions; Tenofovir

2007
[FPV plus SQV plus a mini-dose ritonavir. "Double boosting with compatible partners].
    MMW Fortschritte der Medizin, 2004, Apr-26, Volume: 146 Spec No 1

    Topics: Anti-HIV Agents; Carbamates; Clinical Trials as Topic; Cross-Over Studies; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Organophosphates; Prodrugs; Ritonavir; Saquinavir; Sulfonamides

2004
Steady-State pharmacokinetics of saquinavir hard-gel/ritonavir/fosamprenavir in HIV-1-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2004, Nov-01, Volume: 37, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Area Under Curve; Carbamates; Drug Administration Schedule; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Metabolic Clearance Rate; Middle Aged; Organophosphates; Ritonavir; RNA, Viral; Saquinavir; Sulfonamides; Viral Load

2004
HIV-1 protease mutations and protease inhibitor cross-resistance.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10

    Topics: Atazanavir Sulfate; Carbamates; Darunavir; Furans; HIV Protease; HIV Protease Inhibitors; HIV-1; Indinavir; Least-Squares Analysis; Lopinavir; Mutation; Nelfinavir; Oligopeptides; Organophosphates; Polymorphism, Genetic; Pyridines; Pyrimidinones; Pyrones; Saquinavir; Sulfonamides

2010
Changes in lipid profiles after switching to a protease inhibitor-containing cART--unfavourable effect of fosamprenavir in obese patients.
    European journal of medical research, 2011, Feb-24, Volume: 16, Issue:2

    Topics: Adult; Atazanavir Sulfate; Carbamates; Cholesterol; Cohort Studies; Female; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lipid Metabolism; Male; Middle Aged; Oligopeptides; Organophosphates; Pyridines; Retrospective Studies; Saquinavir; Sulfonamides

2011