Page last updated: 2024-09-03

fosamprenavir and posaconazole

fosamprenavir has been researched along with posaconazole in 4 studies

Compound Research Comparison

Studies
(fosamprenavir)
Trials
(fosamprenavir)
Recent Studies (post-2010)
(fosamprenavir)
Studies
(posaconazole)
Trials
(posaconazole)
Recent Studies (post-2010) (posaconazole)
17455371,5751031,014

Protein Interaction Comparison

ProteinTaxonomyfosamprenavir (IC50)posaconazole (IC50)
Bile salt export pumpHomo sapiens (human)8.1
Steroid 17-alpha-hydroxylase/17,20 lyaseHomo sapiens (human)0.921
Cytochrome P450 3A4Homo sapiens (human)0.2458
AromataseHomo sapiens (human)8.4
Cytochrome P450 2C9 Homo sapiens (human)7.2
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.31
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.021
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.464
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brüggemann, RJ; Burger, DM; Colbers, EP; Pharo, C; Schouwenberg, BJ; van den Dungen, MW; van Luin, M1
Mitra, AK; Pal, D; Patel, M; Paturi, DK; Vadlapatla, RK1
Brüggemann, RJ; Burger, DM; Dolton, MJ; McLachlan, AJ1

Reviews

2 review(s) available for fosamprenavir and posaconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinically relevant drug-drug interactions between antiretrovirals and antifungals.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Alkynes; Anti-Retroviral Agents; Antifungal Agents; Benzoxazines; Carbamates; Cyclopropanes; Drug Interactions; Drug Monitoring; Echinocandins; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Itraconazole; Mycoses; Organophosphates; Pyrimidines; Ritonavir; Sulfonamides; Triazoles; Voriconazole

2014

Trials

1 trial(s) available for fosamprenavir and posaconazole

ArticleYear
Effect of posaconazole on the pharmacokinetics of fosamprenavir and vice versa in healthy volunteers.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:10

    Topics: Adolescent; Adult; Anti-HIV Agents; Antifungal Agents; Carbamates; Cross-Over Studies; Drug Interactions; Female; Furans; Healthy Volunteers; Humans; Male; Middle Aged; Organophosphates; Sulfonamides; Triazoles; Young Adult

2010

Other Studies

1 other study(ies) available for fosamprenavir and posaconazole

ArticleYear
Understanding variability in posaconazole exposure using an integrated population pharmacokinetic analysis.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:11

    Topics: Adult; Anti-HIV Agents; Anticonvulsants; Antiemetics; Antifungal Agents; Biological Availability; Carbamates; Drug Interactions; Drug Therapy, Combination; Furans; Healthy Volunteers; Humans; Metoclopramide; Nucleic Acid Synthesis Inhibitors; Organophosphates; Phenytoin; Proton Pump Inhibitors; Rifampin; Sulfonamides; Triazoles

2014