Page last updated: 2024-09-03

fosamprenavir and darunavir

fosamprenavir has been researched along with darunavir in 6 studies

Compound Research Comparison

Studies
(fosamprenavir)
Trials
(fosamprenavir)
Recent Studies (post-2010)
(fosamprenavir)
Studies
(darunavir)
Trials
(darunavir)
Recent Studies (post-2010) (darunavir)
17455371,148224780

Protein Interaction Comparison

ProteinTaxonomyfosamprenavir (IC50)darunavir (IC50)
Chain A, HIV-1 proteaseHuman immunodeficiency virus 10.0028
Chain B, HIV-1 proteaseHuman immunodeficiency virus 10.0028
Chain A, HIV-1 proteaseHuman immunodeficiency virus 10.0028
Chain B, HIV-1 proteaseHuman immunodeficiency virus 10.0028
ATP-dependent translocase ABCB1Homo sapiens (human)6.6
Protease Human immunodeficiency virus 10.063
Protease Human immunodeficiency virus 10.0014

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babusis, D; Bhoopathy, S; Hidalgo, IJ; Phan, TK; Ray, AS; Rhodes, GR; Robinson, KL; Strab, R; Tong, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Adams, E; Hoogmartens, J; Van Schepdael, A; Yekkala, R1
Fessel, WJ; Hellinger, J; Kaufman, D; Rhee, SY; Ruane, P; Shafer, RW; Shirvani, V; Taylor, J; Towner, W; Troia, P; Zolopa, A1
Alvanzo, AA; Gruber, VA; Ma, Q; McCance-Katz, EF; Moody, DE; Morse, GD; Pade, PA; Prathikanti, S; Rainey, PM1
Di Nicola, M; Falasca, K; Pizzigallo, E; Ucciferri, C; Vecchiet, J; Vignale, F1

Reviews

2 review(s) available for fosamprenavir and darunavir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Quality control of protease inhibitors.
    Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:6

    Topics: Anti-HIV Agents; Atazanavir Sulfate; Carbamates; Chromatography, Liquid; Darunavir; Drug Contamination; Furans; HIV Protease Inhibitors; Indinavir; Lopinavir; Nelfinavir; Oligopeptides; Organophosphates; Pyridines; Pyrimidinones; Pyrones; Quality Control; Ritonavir; Saquinavir; Sulfonamides

2008

Trials

1 trial(s) available for fosamprenavir and darunavir

ArticleYear
Interactions between buprenorphine and the protease inhibitors darunavir-ritonavir and fosamprenavir-ritonavir.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Feb-01, Volume: 54, Issue:3

    Topics: Anti-HIV Agents; Area Under Curve; Buprenorphine; Carbamates; Darunavir; Drug Interactions; Female; Furans; Half-Life; History, 16th Century; History, 17th Century; Humans; Male; Naloxone; Narcotic Antagonists; Opiate Substitution Treatment; Organophosphates; Protease Inhibitors; Ritonavir; Sulfonamides

2012

Other Studies

3 other study(ies) available for fosamprenavir and darunavir

ArticleYear
Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Adenine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; HIV Protease Inhibitors; Humans; Hydrolysis; Indicators and Reagents; Intestinal Absorption; Mass Spectrometry; Organophosphonates; Subcellular Fractions; Tenofovir

2007
HIV-1 protease mutations and protease inhibitor cross-resistance.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:10

    Topics: Atazanavir Sulfate; Carbamates; Darunavir; Furans; HIV Protease; HIV Protease Inhibitors; HIV-1; Indinavir; Least-Squares Analysis; Lopinavir; Mutation; Nelfinavir; Oligopeptides; Organophosphates; Polymorphism, Genetic; Pyridines; Pyrimidinones; Pyrones; Saquinavir; Sulfonamides

2010
Improved metabolic profile after switch to darunavir/ritonavir in HIV positive patients previously on protease inhibitor therapy.
    Journal of medical virology, 2013, Volume: 85, Issue:5

    Topics: Adult; Anti-HIV Agents; Blood Chemical Analysis; Carbamates; CD4 Lymphocyte Count; Darunavir; Dyslipidemias; Female; Follow-Up Studies; Furans; HIV Infections; Humans; Kidney Function Tests; Liver Function Tests; Male; Metabolome; Middle Aged; Organophosphates; Prospective Studies; Protease Inhibitors; Ritonavir; Sulfonamides; White People

2013