forsythoside-b and luteolin-7-glucoside

To investigate the diverse solvent effect on extraction of chemical components from Lamiophlomis rotata.. Based on LC-MS / MS technique, and chromatographic peak comparison, potential chemical components screening and partial least squares-discriminant analysis( PLS-DA) were used to establish a quantitation method for simultaneous determination of chlorogenic acid,forsythoside B,verbascoside,luteoloside,quercetin,luteolin and apigenin.. According to the results of PLS-DA and quantitative analysis, methanol, water-saturated n-butanol,75% methanol and 50% methanol showed wider extraction range and higher extraction efficiency to the chemical components of Lamiophlomis rotata.. This study offeres references to the extraction technology of Lamiophlomis rotata, and promotes the relative pharmacodynamics study of this medical material.

Topics: Caffeic Acids; Chlorogenic Acid; Chromatography, Liquid; Drugs, Chinese Herbal; Glucosides; Lamiaceae; Luteolin; Solvents; Tandem Mass Spectrometry