formylmethionyl-leucyl-phenylalanine methyl ester and n-formylmethionine leucyl-phenylalanine

formylmethionyl-leucyl-phenylalanine methyl ester has been researched along with n-formylmethionine leucyl-phenylalanine in 59 studies

Compound Research Comparison

Studies (formylmethionyl-leucyl-phenylalanine methyl ester)	Trials (formylmethionyl-leucyl-phenylalanine methyl ester)	Recent Studies (post-2010) (formylmethionyl-leucyl-phenylalanine methyl ester)	Studies (n-formylmethionine leucyl-phenylalanine)	Trials (n-formylmethionine leucyl-phenylalanine)	Recent Studies (post-2010) (n-formylmethionine leucyl-phenylalanine)
67	1	6	6,716	53	356

Protein Interaction Comparison

Protein	Taxonomy	formylmethionyl-leucyl-phenylalanine methyl ester (IC50)	n-formylmethionine leucyl-phenylalanine (IC50)
fMet-Leu-Phe receptor	Homo sapiens (human)		0.02

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (13.56)	18.7374
1990's	9 (15.25)	18.2507
2000's	36 (61.02)	29.6817
2010's	6 (10.17)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
LeDuc, LE; Nast, CC	1
Gavuzzo, E; Mazza, F; Pochetti, G; Scatturin, A	1
Kang, DC; Minakami, S; Tekeshige, K	1
Houben, LA; Huidekoper, HJ; Terpstra, GK	1
Obrecht, JP; Obrist, R; Schmidli, J	1
Briheim, G; Coble, B; Dahlgren, C; Stendahl, O	1
Cavalletti, T; Gavioli, R; Scatturin, A; Spisani, S; Traniello, S; Vertuani, G	1
Balaram, P; Raj, PA	1
Cavalletti, T; Gavioli, R; Marangoni, C; Scatturin, A; Spisani, S; Traniello, S; Vertuani, G	1
Lucente, G; Pagani Zecchini, G; Paglialunga Paradisi, M; Spisani, S; Torrini, I	1
Gavuzzo, E; Lucente, G; Mazza, F; Pagani Zecchini, G; Paglialunga Paradisi, M; Pochetti, G; Spisani, S; Torrini, I; Traniello, S	2
Gavuzzo, E; Lucente, G; Mastropietro, G; Mazza, F; Pagani Zecchini, G; Paglialunga Paradisi, M; Pochetti, G; Spisani, S; Torrini, I; Traniello, S	1
Biondi, C; Buzzi, M; Colamussi, ML; Ferretti, ME; Pagani Zecchini, G; Paglialunga Paradisi, M; Pareschi, MC; Spisani, S; Torrini, I; Traniello, S	1
Barrett, JA; Boerman, OC; Corstens, FH; Edwards, DS; Oyen, WJ; van de Ven, MT; van der Laken, CJ; van der Meer, JW	1
Lucente, G; Mastropietro, G; Pagani Zecchini, G; Paglialunga Paradisi, M; Spisani, S; Torrini, I	2
Lucente, G; Nalli, M; Paradisi, MP; Spisani, S; Torrini, I; Zecchini, GP	1
Biondi, C; Colamussi, ML; Ferretti, ME; Nalli, M; Pavan, B; Spisani, S; Traniello, S	1
Buridi, A; Coxon, PY; Kettritz, R; Klein, JB; Manning, T; McLeish, KR; Rane, MJ	1
Lucente, G; Nalli, M; Pagani Zecchini, G; Paglialunga Paradisi, M; Spisani, S; Torrini, I	1
Belleguic, C; Boichot, E; Corbel, M; Germain, N; Lagente, V	1
Cavicchioni, G; Spisani, S	1
Biffl, WL; Ciesla, DJ; Gonzalez, RJ; Moore, EE; Moore, HB; Silliman, CC	1
Clay, K; Dinauer, M; Hiran, T; Johnson, C; Travers, J	1
Corteling, R; Trifilieff, A; Wyss, D	1
Kistler, EB; Mitsuoka, H; Schmid-Schönbein, GW	1
Dackiw, AP; Marshall, JC; McGilvray, ID; Rotstein, OD; Tsai, V	1
Cavicchioni, G; Spisani, S; Turchetti, M	1
Anderson, SI; Behrendt, B; Insall, RH; Machesky, LM; Nash, GB	1
Aktories, K; Bourne, HR; Glavas, S; Hofmann, F; Kalman, D; Ott, A; Srinivasan, S; Wang, F	1
Bland, KI; Chaudrya, IH; Kuebler, JF; Schwacha, MG; Toth, B; Wang, P	1
Falzarano, S; Pagani Zecchini, G; Selvatici, R; Spisani, S; Traniello, S	1
Chang, CY; Chang, LC; Hsu, MF; Huang, LJ; Kuo, SC; Lin, YL; Wang, JP	1
Fink, M; Karst, M; Piepenbrock, S; Rueckert, T; Scheinichen, D; Wagner, T; Wiese, B	1
Alexander, JS; Blaschuk, O; Elrod, JW; Gour, B; Jackson, TH; Oshima, T; Sasaki, M; Symonds, M	1
Cavicchioni, G; Falzarano, S; Spisani, S; Turchetti, M; Varani, K	1
Bourne, HR; Herzmark, P; Kelly, K; Mitchison, T; Straight, A; Sugimoto, N; Takuwa, Y; Van Keymeulen, A; Wang, F; Xu, J	1
Giordano, C; Lucente, G; Nalli, M; Pagani Zecchini, G; Paglialunga Paradisi, M; Spisani, S; Varani, K	1
Chen, CF; Liou, KT; Shen, YC; Tsai, SK; Tsao, CM	1
Gavuzzo, E; Giordano, C; Lucente, G; Mazza, F; Mollica, A; Nalli, M; Pagani Zecchini, G; Paglialunga Paradisi, M; Spisani, S	1
Giordano, C; Lucente, G; Nalli, M; Paradisi, MP; Sansone, A; Spisani, S	1
Cavicchioni, G; Falzarano, S; Fraulini, A; Pavan, B; Spisani, S; Turchetti, M; Varani, K	1
Aida, Y; Jinnouchi, A; Maeda, K; Nozoe, K; Pabst, MJ	1
Borgeat, P; Bourgoin, S; Fernandes, M; Fortin, A; Harbour, D	1
Giordano, C; Lucente, G; Masi, A; Paglialunga Paradisi, M; Sansone, A; Spisani, S	1
Chang, HL; Hwang, TL; Kao, SH; Leu, YL; Tang, MC	1
Angco, G; Dent, G; Djukanovic, R; Hirata, K; Nomura, N; Nong, G; Ward, J; Yoshikawa, T	1
Kato, J; Kogawa, K; Kuribayashi, K; Matsunaga, T; Nakamura, K; Niitsu, Y; Onuma, T; Sasaki, K; Sato, T; Takayama, T; Takimoto, R; Tanaka, M; Terui, T	1
Cavicchioni, G; Falzarano, S; Fraulini, A; Spisani, S; Varani, K	1
Giordano, C; Lucente, G; Sansone, A; Spisani, S; Torino, D	1
Ballabeni, V; Barocelli, E; Bondavalli, F; Brullo, C; Bruno, O; Falzarano, MS; Giorgio, C; Schenone, S; Spisani, S; Tognolini, M; Varani, K	1
Cara, DC; Kubes, P; Lee, WY; Menezes, GB; Waterhouse, CC; Zhou, H	1
Ahluwalia, J; Salmon, MD	1
De Rosa, A; Lichtner, M; Massetti, AP; Mastroianni, CM; Mengoni, F; Rossi, R; Sauzullo, I; Vullo, V	1
Brullo, C; Bruno, O; Selvatici, R; Spisani, S	1
Costante, R; Feliciani, F; Lucente, G; Mollica, A; Notaristefano, D; Pinnen, F; Spisani, S; Stefanucci, A	1
Djerdjouri, B; El-Benna, J; Elkrief, L; Hadjoudj, S; Makhezer, N; Moreau, R; Périanin, A; Rolas, L	1
Itakura, A; McCarty, OJ	1

Reviews

1 review(s) available for formylmethionyl-leucyl-phenylalanine methyl ester and n-formylmethionine leucyl-phenylalanine

Article	Year
[Regulation of degranulation and protein kinase C]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1986, Volume: 31, Issue:6 Topics: Blood Glucose; Blood Platelets; Calcium; Cyclic AMP; Insulin; Insulin Secretion; Islets of Langerhans; Myosins; N-Formylmethionine Leucyl-Phenylalanine; Neurotransmitter Agents; Neutrophils; Phosphatidylinositols; Phosphorylation; Protein Kinase C	1986

Trials

1 trial(s) available for formylmethionyl-leucyl-phenylalanine methyl ester and n-formylmethionine leucyl-phenylalanine

Article	Year
Effect of acupuncture on the neutrophil respiratory burst: a placebo-controlled single-blinded study. Complementary therapies in medicine, 2003, Volume: 11, Issue:1 Topics: Acupuncture Therapy; Adult; beta-Endorphin; Escherichia coli; Female; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tumor Necrosis Factor-alpha	2003

Other Studies

57 other study(ies) available for formylmethionyl-leucyl-phenylalanine methyl ester and n-formylmethionine leucyl-phenylalanine

Article	Year
Chemotactic peptide-induced acute colitis in rabbits. Gastroenterology, 1990, Volume: 98, Issue:4 Topics: Animals; Bradykinin; Chemotactic Factors; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Colitis; Dinoprostone; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Rabbits; SRS-A	1990
Crystal structure, conformation, and potential energy calculations of the chemotactic peptide N-formyl-L-Met-L-Leu-L-Phe-OMe. International journal of peptide and protein research, 1989, Volume: 34, Issue:5 Topics: Crystallography; Models, Molecular; N-Formylmethionine Leucyl-Phenylalanine; Protein Conformation; Software; Thermodynamics	1989
Neutrophil accumulation in chronic obstructive lung disease. Lancet (London, England), 1988, Jan-30, Volume: 1, Issue:8579 Topics: Bronchiectasis; Chemotaxis, Leukocyte; Humans; Lung Diseases, Obstructive; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Emphysema	1988
Chemotactic monoclonal antibody conjugates: a comparison of four different f-Met-peptide-conjugates. Biochemical and biophysical research communications, 1988, Sep-30, Volume: 155, Issue:3 Topics: Animals; Antibodies, Monoclonal; Chemotaxis; Dipeptides; Dose-Response Relationship, Drug; Humans; Immunotoxins; Mice; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides	1988
Exudate polymorphonuclear leukocytes isolated from skin chambers are primed for enhanced response to subsequent stimulation with chemoattractant f-Met-Leu-Phe and C3-opsonized yeast particles. Inflammation, 1988, Volume: 12, Issue:2 Topics: Chemotaxis, Leukocyte; Complement C3; Exudates and Transudates; Humans; In Vitro Techniques; Inflammation; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Skin; Yeasts	1988
Response of human neutrophils to formyl-peptide modified at the terminal amino and carboxyl groups. Inflammation, 1986, Volume: 10, Issue:4 Topics: Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Structure-Activity Relationship	1986
Conformational effects on peptide aggregation in organic solvents: spectroscopic studies of two chemotactic tripeptide analogs. Biopolymers, 1985, Volume: 24, Issue:7 Topics: Circular Dichroism; N-Formylmethionine Leucyl-Phenylalanine; Protein Conformation; Structure-Activity Relationship	1985
[An analog of formyl-met-leu-phe effects the movement of human leukocytes]. Bollettino della Societa italiana di biologia sperimentale, 1984, Jun-30, Volume: 60, Issue:6 Topics: Binding Sites; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils	1984
Modified chemotactic peptides: synthesis and biological activity of HCO-Met-delta ZLeu-delta ZPhe-OMe. Farmaco (Societa chimica italiana : 1989), 1994, Volume: 40, Issue:11 Topics: Amino Acid Sequence; Chemotactic Factors; Humans; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Structure-Activity Relationship	1994
Modified chemotactic peptides: synthesis, crystal conformation, and activity of For-Hse(Me)-Leu-Phe-OMe. Biopolymers, 1994, Volume: 34, Issue:1 Topics: Amino Acid Sequence; Chemotactic Factors; Crystallization; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Protein Conformation	1994
Modified chemotactic peptides: synthesis, conformation, and activity of HCO-Thp-Ac6c-Phe-OMe. Biopolymers, 1996, Volume: 39, Issue:3 Topics: Amino Acid Sequence; Chemotactic Factors; Humans; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Protein Conformation	1996
Effect of cyclic AMP level reduction on human neutrophil responses to formylated peptides. Cellular signalling, 1996, Volume: 8, Issue:4 Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Chemotaxis, Leukocyte; Cyclic AMP; Dipyridamole; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides	1996
Technetium-99m-labeled chemotactic peptides in acute infection and sterile inflammation. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:8 Topics: Abscess; Animals; Chemotactic Factors; Chemotaxis, Leukocyte; Escherichia coli Infections; Female; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Organotechnetium Compounds; Rabbits; Radionuclide Imaging; Soft Tissue Infections; Staphylococcal Infections; Technetium; Zymosan	1997
Synthesis, conformation, and biological activity of two fMLP-OMe analogues containing the new 2-[2'-(methylthio)ethyl]methionine residue. Biopolymers, 1997, Oct-05, Volume: 42, Issue:4 Topics: Chemotaxis, Leukocyte; Humans; Methionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Protein Conformation	1997
New fMLF-OMe analogues containing constrained mimics of phenylalanine residue. Archiv der Pharmazie, 1998, Volume: 331, Issue:5 Topics: Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Molecular Mimicry; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylalanine; Superoxides	1998
Modified chemotactic peptides: synthesis and activity of an azaTic-containing fMLP-OMe analogue. Amino acids, 1998, Volume: 14, Issue:4 Topics: Carboxylic Acids; Chemotaxis, Leukocyte; Magnetic Resonance Spectroscopy; Models, Chemical; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines	1998
Biscarbamate analogues of the chemotactic tripeptide fMLF-OMe. Farmaco (Societa chimica italiana : 1989), 2000, Volume: 55, Issue:4 Topics: Carbamates; Chemotactic Factors; Humans; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides	2000
Modulation of neutrophil phospholipase C activity and cyclic AMP levels by fMLP-OMe analogues. Cellular signalling, 2001, Volume: 13, Issue:4 Topics: Calcimycin; Calcium; Cells, Cultured; Chemotaxis, Leukocyte; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Humans; Ionophores; Ligands; Models, Chemical; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrrolidinones; Superoxides; Time Factors; Type C Phospholipases	2001
Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and LPS delay of constitutive neutrophil apoptosis. Cellular signalling, 2001, Volume: 13, Issue:5 Topics: Androstadienes; Apoptosis; Chemotaxis, Leukocyte; Chromones; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Leukotriene B4; Lipopolysaccharides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Virulence Factors, Bordetella; Wortmannin	2001
Pseudopeptides containing the 2-hydrazonoacyl fragment: analogs of the chemotactic agent HCO-Met-Leu-Phe-OMe. The journal of peptide research : official journal of the American Peptide Society, 2001, Volume: 58, Issue:1 Topics: Biochemistry; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Structure-Activity Relationship; Superoxides	2001
Effects of PDE4 inhibitors on lipopolysaccharide-induced priming of superoxide anion production from human mononuclear cells. Mediators of inflammation, 2001, Volume: 10, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Benzamides; Bucladesine; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Interleukin-10; Leukocytes, Mononuclear; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Phosphodiesterase Inhibitors; Pyridines; Rolipram; Superoxides; Time Factors	2001
A hydrophilic residue at position 2 can improve specific biological responses in fMLP-OMe analogs. The journal of peptide research : official journal of the American Peptide Society, 2001, Volume: 58, Issue:3 Topics: Amino Acid Substitution; Chemotaxis; Humans; In Vitro Techniques; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Superoxides	2001
Hypertonic saline activation of p38 MAPK primes the PMN respiratory burst. Shock (Augusta, Ga.), 2001, Volume: 16, Issue:4 Topics: Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; p38 Mitogen-Activated Protein Kinases; Pyridines; Respiratory Burst; Saline Solution, Hypertonic; Superoxides; Tetradecanoylphorbol Acetate	2001
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985. Prostaglandins & other lipid mediators, 2001, Volume: 66, Issue:4 Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate	2001
In vivo models of lung neutrophil activation. Comparison of mice and hamsters. BMC pharmacology, 2002, Volume: 2 Topics: Animals; Cricetinae; Female; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Species Specificity	2002
Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock. Shock (Augusta, Ga.), 2002, Volume: 17, Issue:3 Topics: Animals; Blood Pressure; Endopeptidases; Esters; Gabexate; Guanidines; Humans; In Vitro Techniques; Inflammation; Intestinal Mucosa; Intestines; Leukocytes; Male; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phospholipases A; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Reperfusion; Serine Endopeptidases; Serine Proteinase Inhibitors; Shock; Splanchnic Circulation; Survival Rate	2002
Monocyte adhesion and transmigration induce tissue factor expression: role of the mitogen-activated protein kinases. Shock (Augusta, Ga.), 2002, Volume: 18, Issue:1 Topics: Antibodies; CD18 Antigens; Cell Adhesion; Cell Movement; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Flavonoids; Humans; Imidazoles; Inflammation; Integrin beta1; Mitogen-Activated Protein Kinases; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Pyridines; Thromboplastin; Tumor Necrosis Factor-alpha	2002
Biological variation responses in fMLP-OMe analogs, introducing bulky protecting groups on the side-chain of hydrophilic residues at position 2. The journal of peptide research : official journal of the American Peptide Society, 2002, Volume: 60, Issue:4 Topics: Chemotaxis, Leukocyte; Chromatography, Thin Layer; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Structure-Activity Relationship; Superoxides	2002
Linked regulation of motility and integrin function in activated migrating neutrophils revealed by interference in remodelling of the cytoskeleton. Cell motility and the cytoskeleton, 2003, Volume: 54, Issue:2 Topics: Actin-Related Protein 2; Actin-Related Protein 3; Actins; Bacterial Proteins; CD11b Antigen; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cell Size; Cytoskeletal Proteins; Cytoskeleton; Humans; Membrane Proteins; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmotic Pressure; Peptide Fragments; Phosphoproteins; Polymers; Proteins; Vinculin; Wiskott-Aldrich Syndrome Protein; Wiskott-Aldrich Syndrome Protein Family	2003
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. The Journal of cell biology, 2003, Feb-03, Volume: 160, Issue:3 Topics: Actins; Animals; Bacterial Toxins; cdc42 GTP-Binding Protein; Cell Membrane; Cell Polarity; Chemotaxis, Leukocyte; COS Cells; Feedback, Physiological; Green Fluorescent Proteins; HL-60 Cells; Humans; Inositol Phosphates; Luminescent Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p21-Activated Kinases; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pseudopodia; rac GTP-Binding Proteins; Recombinant Fusion Proteins	2003
Gender dimorphism in neutrophil priming and activation following trauma-hemorrhagic shock. International journal of molecular medicine, 2003, Volume: 11, Issue:3 Topics: Animals; Chemokines, CXC; Chemotaxis, Leukocyte; Female; Lipopolysaccharides; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Peroxidase; Rats; Rats, Sprague-Dawley; Resuscitation; Sex Characteristics; Shock, Hemorrhagic; Superoxides; Thiobarbituric Acid Reactive Substances; Wounds and Injuries	2003
Formylpeptides trigger selective molecular pathways that are required in the physiological functions of human neutrophils. Cellular signalling, 2003, Volume: 15, Issue:4 Topics: Calcium; Calcium Signaling; Cells, Cultured; Chemotaxis, Leukocyte; Enzyme Activation; Humans; In Vitro Techniques; Mitogen-Activated Protein Kinase Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Superoxides	2003
Investigation of the cellular mechanism of inhibition of formyl-methionyl-leucyl-phenylalanine-induced superoxide anion generation in rat neutrophils by 2-benzyloxybenzaldehyde. Biochemical pharmacology, 2003, Apr-01, Volume: 65, Issue:7 Topics: Animals; Benzaldehydes; Calcium; Cyclic AMP; Drug Interactions; Enzyme Activation; In Vitro Techniques; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Superoxides	2003
Tight junction peptide antagonists enhance neutrophil trans-endothelial chemotaxis. Life sciences, 2003, Aug-15, Volume: 73, Issue:13 Topics: Adult; Cadherins; Cells, Cultured; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Endothelium, Vascular; Enkephalins; Fluorescent Antibody Technique; Humans; Infant, Newborn; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Occludin; Protein Precursors; Tight Junctions; Time Factors	2003
Properties of a novel chemotactic esapeptide, an analogue of the prototypical N-formylmethionyl peptide. Bioorganic chemistry, 2003, Volume: 31, Issue:4 Topics: Chemotaxis; Humans; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tritium	2003
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils. Cell, 2003, Jul-25, Volume: 114, Issue:2 Topics: cdc42 GTP-Binding Protein; Cell Polarity; Chemotaxis, Leukocyte; Cytoskeleton; HL-60 Cells; Humans; Models, Biological; Mutation; Myosin Type II; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pseudopodia; rac GTP-Binding Proteins; Recombinant Fusion Proteins; rhoA GTP-Binding Protein; Signal Transduction; Transfection	2003
Synthesis and activity of HCO-Met-Leu-Phe-OMe analogues containing beta-alanine or taurine at the central position. Farmaco (Societa chimica italiana : 1989), 2003, Volume: 58, Issue:11 Topics: beta-Alanine; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Binding; Taurine	2003
Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production. Brain research, 2003, Dec-05, Volume: 992, Issue:2 Topics: Animals; Biphenyl Compounds; Brain Ischemia; Calcium; Calcium Signaling; Cell Adhesion; Cerebral Infarction; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Lignans; Lipid Peroxidation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neuroprotective Agents; Neutrophils; Rats; Rats, Long-Evans; Reactive Oxygen Species; Reperfusion Injury; Tetradecanoylphorbol Acetate	2003
Hybrid alpha/beta3-peptides with proteinogenic side chains. Monosubstituted analogues of the chemotactic tripeptide For-Met-Leu-Phe-OMe. Journal of peptide science : an official publication of the European Peptide Society, 2004, Volume: 10, Issue:8 Topics: Amino Acid Sequence; Chemotaxis, Leukocyte; Crystallization; Humans; Molecular Conformation; Molecular Sequence Data; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Structure-Activity Relationship; Superoxides; X-Ray Diffraction	2004
Beta-peptido sulfonamides: for-Met-Leu-Phe-OMe analogues containing taurine and chiral beta-amino-ethanesulfonic acid residues. Farmaco (Societa chimica italiana : 1989), 2004, Volume: 59, Issue:12 Topics: Chemotaxis; Dose-Response Relationship, Drug; Ethanolamines; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stereoisomerism; Sulfonamides; Sulfonic Acids; Taurine	2004
Biological activity of for-Met-Leu-Phe-OMe analogs: relevant substitutions specifically trigger killing mechanisms in human neutrophils. European journal of pharmacology, 2005, Apr-04, Volume: 512, Issue:1 Topics: Binding, Competitive; Chemotaxis, Leukocyte; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Radioligand Assay; Structure-Activity Relationship; Superoxides	2005
Local anesthetics inhibit priming of neutrophils by lipopolysaccharide for enhanced release of superoxide: suppression of cytochrome b558 expression by disparate mechanisms. Journal of leukocyte biology, 2005, Volume: 78, Issue:6 Topics: Anesthetics, Local; Cells, Cultured; Cytochrome b Group; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Feedback, Physiological; Humans; Lipopolysaccharides; MAP Kinase Signaling System; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phagocytosis; Signal Transduction; Superoxides; Transport Vesicles	2005
Differential expression of adenosine receptors in human neutrophils: up-regulation by specific Th1 cytokines and lipopolysaccharide. Journal of leukocyte biology, 2006, Volume: 79, Issue:3 Topics: Adenosine; Antihypertensive Agents; Cells, Cultured; Cytokines; Enzyme Inhibitors; Humans; Inflammation Mediators; Leukotrienes; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Phospholipase D; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Superoxides; Th1 Cells; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation	2006
Synthesis, conformation and biological activity of centrally modified pseudopeptidic analogues of For-Met-Leu-Phe-OMe. Amino acids, 2007, Volume: 33, Issue:3 Topics: Chemotaxis, Leukocyte; Humans; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nuclear Magnetic Resonance, Biomolecular; Peptides; Solvents; Superoxides	2007
Viscolin, a new chalcone from Viscum coloratum, inhibits human neutrophil superoxide anion and elastase release via a cAMP-dependent pathway. Free radical biology & medicine, 2006, Nov-01, Volume: 41, Issue:9 Topics: Biphenyl Compounds; Calcium; Chemotaxis, Leukocyte; Cyclic AMP; Cytosol; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Propane; Signal Transduction; Superoxides; Viscum	2006
Impaired neutrophil chemotaxis in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine, 2007, Mar-01, Volume: 175, Issue:5 Topics: Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Female; Humans; Interleukin-8; Leukocyte Count; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Sputum	2007
Essential role of protein kinase C zeta in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP. The Journal of cell biology, 2007, Mar-26, Volume: 176, Issue:7 Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cell Movement; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Guanine Nucleotide Dissociation Inhibitors; Humans; Inflammation; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Invasiveness; Oxidative Stress; Protein Kinase C; rho GTP-Binding Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Signal Transduction; Superoxide Dismutase; Superoxides	2007
New chemotactic dimeric peptides show high affinity and potency at the human formylpeptide receptor. European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2 Topics: Amino Acids, Neutral; Aminocaproic Acid; Binding, Competitive; Chemotaxis, Leukocyte; Dimerization; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Radioligand Assay; Receptors, Formyl Peptide; Structure-Activity Relationship; Superoxides	2007
Synthesis and bioactivity of chemotactic tetrapeptides: fMLF-OMe analogues incorporating spacer aminoacids at the lateral positions. Amino acids, 2009, Volume: 37, Issue:2 Topics: Amino Acids; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides	2009
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors. Bioorganic & medicinal chemistry, 2009, May-01, Volume: 17, Issue:9 Topics: Animals; Chemotaxis, Leukocyte; Drug Design; Esters; Humans; Inhibitory Concentration 50; Interleukin-8; Male; Mice; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Binding; Pyrazoles; Structure-Activity Relationship	2009
Selective down-regulation of neutrophil Mac-1 in endotoxemic hepatic microcirculation via IL-10. Journal of immunology (Baltimore, Md. : 1950), 2009, Dec-01, Volume: 183, Issue:11 Topics: Animals; Brain; Cell Adhesion; Cell Adhesion Molecules; Down-Regulation; Endotoxemia; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hyaluronan Receptors; Inflammation; Interleukin-10; Lipopolysaccharides; Liver; Macrophage-1 Antigen; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Microscopy, Confocal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Infiltration; Neutrophils	2009
Discrimination between receptor- and store-operated Ca(2+) influx in human neutrophils. Cellular immunology, 2010, Volume: 265, Issue:1 Topics: Boron Compounds; Calcium; Humans; Immunologic Factors; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Calcium-Sensing; Spectrometry, Fluorescence; Strontium	2010
In vitro effect of anti-human immunodeficiency virus CCR5 antagonist maraviroc on chemotactic activity of monocytes, macrophages and dendritic cells. Clinical and experimental immunology, 2011, Volume: 166, Issue:2 Topics: CCR5 Receptor Antagonists; Chemokine CCL2; Chemokine CCL4; Chemokine CCL5; Chemotaxis; Chemotaxis, Leukocyte; Cyclohexanes; Dendritic Cells; HIV Fusion Inhibitors; HIV Infections; Humans; Macrophages; Maraviroc; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Receptors, CCR5; Triazoles	2011
N-Aryl-2-phenyl-2,3-dihydro-imidazo[1,2-b]pyrazole-1-carboxamides 7-substituted strongly inhibiting both fMLP-OMe- and IL-8-induced human neutrophil chemotaxis. European journal of medicinal chemistry, 2012, Volume: 47, Issue:1 Topics: Chemotaxis; Humans; Inhibitory Concentration 50; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyrazoles; Structure-Activity Relationship	2012
Synthesis and biological evaluation of new active For-Met-Leu-Phe-OMe analogues containing para-substituted Phe residues. Journal of peptide science : an official publication of the European Peptide Society, 2012, Volume: 18, Issue:6 Topics: Amino Acid Sequence; Anions; Chemotaxis; Humans; Molecular Conformation; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phenylalanine; Reference Values; Stereoisomerism; Superoxides	2012
Inhibition of mammalian target of rapamycin aggravates the respiratory burst defect of neutrophils from decompensated patients with cirrhosis. Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:3 Topics: Antibiotics, Antineoplastic; Cytosol; Drug Interactions; Escherichia coli Infections; Female; HL-60 Cells; Humans; Liver Cirrhosis, Alcoholic; Male; MAP Kinase Signaling System; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Phosphorylation; Respiratory Burst; Sirolimus; TOR Serine-Threonine Kinases	2013
Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy. American journal of physiology. Cell physiology, 2013, Aug-01, Volume: 305, Issue:3 Topics: Autophagy; DNA; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phagocytosis; Signal Transduction; TOR Serine-Threonine Kinases	2013