Compounds > formoterol fumarate

formoterol fumarate and salmeterol xinafoate

formoterol fumarate has been researched along with salmeterol xinafoate in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (21.05)29.6817
2010's15 (78.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alikhani, V; Beer, D; Bentley, D; Bruce, I; Cuenoud, BM; Fairhurst, RA; Gedeck, P; Haberthuer, S; Hayden, C; Janus, D; Jordan, L; Lewis, C; Smithies, K; Wissler, E1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barrett, VJ; Bevan, NJ; Biggadike, K; Butchers, PR; Coe, DM; Conroy, R; Edney, DD; Field, RN; Ford, AJ; Guntrip, SB; Looker, BE; McLay, IM; Monteith, MJ; Morrison, VS; Mutch, PJ; Procopiou, PA; Richards, SA; Sasse, R; Smith, CE1
Baur, F; Beattie, D; Beer, D; Bentley, D; Bradley, M; Bruce, I; Charlton, SJ; Cuenoud, B; Ernst, R; Fairhurst, RA; Faller, B; Farr, D; Fozard, JR; Fullerton, J; Garman, S; Hatto, J; Hayden, C; He, H; Howes, C; Janus, D; Jiang, Z; Keller, T; Lewis, C; Loeuillet-Ritzler, F; Moser, H; Reilly, J; Steward, A; Sykes, D; Tedaldi, L; Trifilieff, A; Tweed, M; Watson, S; Wissler, E; Wyss, D1
Baker, JG1
Beattie, D; Bradley, M; Brearley, A; Charlton, SJ; Cuenoud, BM; Fairhurst, RA; Gedeck, P; Gosling, M; Janus, D; Jones, D; Lewis, C; McCarthy, C; Oakman, H; Stringer, R; Taylor, RJ; Tuffnell, A1
Brown, AD; Bunnage, ME; Burrows, JL; Clarke, NP; Feeder, N; Glossop, PA; James, K; Jones, RM; Lane, CA; Lewthwaite, RA; Perros-Huguet, C; Price, DA; Spence, FJ; Taylor, SC; Trevethick, MA; Webster, R; Yeadon, M1
Chin, KH; Dunham, SL; Hughes, AD; Jasper, JR; King, KE; Lee, TW; Mammen, M; Martin, J; Steinfeld, T1
Alcaraz, L; Bailey, A; Bonnert, R; Cadogan, E; Christie, J; Connolly, S; Cook, A; Fisher, A; Flaherty, A; Hill, S; Humphries, A; Ingall, A; Jordan, S; Lawson, M; Mullen, A; Nicholls, D; Paine, S; Pairaudeau, G; St-Gallay, S; Stocks, MJ; Young, A1
Barrett, VJ; Bevan, NJ; Butchers, PR; Conroy, R; Emmons, A; Ford, AJ; Jeulin, S; Looker, BE; Lunniss, GE; Morrison, VS; Mutch, PJ; Perciaccante, R; Procopiou, PA; Ruston, M; Smith, CE; Somers, G1
Alcaraz, L; Bailey, A; Cadogan, E; Christie, J; Connolly, S; Cook, AR; Fisher, AJ; Hill, S; Humphries, A; Ingall, AH; Kane, Z; Paine, S; Pairaudeau, G; Stocks, MJ; Young, A1
Alcaraz, L; Bailey, A; Cadogan, E; Connolly, S; Dainty, I; Jewell, R; Jordan, S; Kindon, N; Lawson, M; Lister, A; Mullen, A; Nicholls, D; Paine, S; Pairaudeau, G; Stocks, MJ; Thorne, P; Young, A1
Aggen, JB; Church, TJ; Jacobsen, JR; Klein, U; Moran, EJ; Pfeiffer, JW; Pulido-Rios, TM; Thomas, GR; Yu, C1
Jacobsen, JR; Klein, U; Linsell, MS; McKinnell, RM; Moran, EJ; Nodwell, MB; Pfeiffer, JW; Thomas, GR; Yu, C1
Alcaraz, L; Bailey, A; Bonnert, R; Cadogan, E; Christie, J; Connolly, S; Cook, A; Dixon, J; Fisher, A; Flaherty, A; Humphries, A; Ingall, A; Jordan, S; Lawson, M; Mullen, A; Nicholls, D; Paine, S; Pairaudeau, G; Stocks, MJ; Young, A1
Arnold, N; Beattie, D; Bradley, M; Brearley, A; Brown, L; Charlton, SJ; Fairhurst, RA; Farr, D; Fozard, J; Fullerton, J; Gosling, M; Hatto, J; Janus, D; Jones, D; Jordan, L; Lewis, C; Maas, J; McCarthy, C; Mercer, M; Oakman, H; Press, N; Profit, R; Schuerch, F; Sykes, D; Taylor, RJ; Trifilieff, A; Tuffnell, A1
Gmeiner, P; Hübner, H; Stanek, M; Weichert, D1
Healy, MP; Reilly, J; Sandham, DA; Shaw, DE; Wang, B; Yan, S; Yang, L1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Other Studies

19 other study(ies) available for formoterol fumarate and salmeterol xinafoate

ArticleYear
Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the beta2-adrenoceptor activity.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Animals; Ethanolamines; Formoterol Fumarate; Guinea Pigs; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Salmeterol Xinafoate; Stereoisomerism; Structure-Activity Relationship; Time Factors

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups.
    Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8

    Topics: 2-Hydroxyphenethylamine; Administration, Oral; Adrenergic beta-2 Receptor Agonists; Albuterol; Animals; Biological Availability; Bronchi; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Microsomes; Models, Molecular; Muscle Contraction; Muscle, Smooth; Rats; Salmeterol Xinafoate; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Trachea

2009
The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist.
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Animals; Bronchodilator Agents; Guinea Pigs; Humans; Hydrophobic and Hydrophilic Interactions; Indans; Quinolones; Structure-Activity Relationship

2010
The selectivity of beta-adrenoceptor agonists at human beta1-, beta2- and beta3-adrenoceptors.
    British journal of pharmacology, 2010, Volume: 160, Issue:5

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Humans; Propanolamines; Radioligand Assay

2010
A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of beta2-adrenoceptor agonists as inhaled long-acting bronchodilators.
    Bioorganic & medicinal chemistry letters, 2010, Sep-01, Volume: 20, Issue:17

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Antagonists; Bronchodilator Agents; Thiazoles

2010
Inhalation by design: novel ultra-long-acting β(2)-adrenoreceptor agonists for inhaled once-daily treatment of asthma and chronic obstructive pulmonary disease that utilize a sulfonamide agonist headgroup.
    Journal of medicinal chemistry, 2010, Sep-23, Volume: 53, Issue:18

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Asthma; Benzeneacetamides; Bronchoconstriction; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Dogs; Female; Guinea Pigs; Hepatocytes; Humans; In Vitro Techniques; Liver; Male; Microsomes, Liver; Models, Molecular; Molecular Structure; Muscle, Smooth; Pulmonary Disease, Chronic Obstructive; Rats; Stereoisomerism; Sulfonamides; Trachea

2010
Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules.
    Bioorganic & medicinal chemistry letters, 2011, Mar-01, Volume: 21, Issue:5

    Topics: Adrenergic beta-2 Receptor Agonists; Bronchodilator Agents; Drug Design; Humans; Molecular Structure; Muscarinic Antagonists; Receptors, Adrenergic, beta-2; Receptors, Muscarinic; Structure-Activity Relationship

2011
Design driven HtL: The discovery and synthesis of new high efficacy β₂-agonists.
    Bioorganic & medicinal chemistry letters, 2011, Jul-01, Volume: 21, Issue:13

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Bronchi; Cell Line; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2011
The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating hydantoin or uracil rings.
    Bioorganic & medicinal chemistry, 2011, Jul-15, Volume: 19, Issue:14

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; CHO Cells; Cricetinae; Cricetulus; Dogs; Dose-Response Relationship, Drug; Drug Discovery; Female; Guinea Pigs; Hepatocytes; Humans; Hydantoins; Male; Microsomes, Liver; Molecular Structure; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Stereoisomerism; Trachea; Uracil

2011
Design-driven LO: the discovery of new ultra long acting dibasic β2-adrenoceptor agonists.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Bronchodilator Agents; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Receptors, Adrenergic, beta-2; Structure-Activity Relationship; Thiazoles

2011
From libraries to candidate: the discovery of new ultra long-acting dibasic β₂-adrenoceptor agonists.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Asthma; Bronchodilator Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Cyclic AMP; Drug Design; Guinea Pigs; Humans; Inhibitory Concentration 50; Models, Chemical; Protein Binding; Pulmonary Disease, Chronic Obstructive; Thiazoles; Time Factors

2012
Multivalent design of long-acting β(2)-adrenoceptor agonists incorporating biarylamines.
    Bioorganic & medicinal chemistry letters, 2014, Jun-15, Volume: 24, Issue:12

    Topics: Adrenergic beta-2 Receptor Agonists; Amines; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Guinea Pigs; Humans; Lung Diseases, Obstructive; Molecular Structure

2014
Discovery of TD-4306, a long-acting β2-agonist for the treatment of asthma and COPD.
    Bioorganic & medicinal chemistry letters, 2014, Jul-01, Volume: 24, Issue:13

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Asthma; Cell Line; Diphenylamine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Discovery; Guinea Pigs; Humans; Molecular Structure; Pulmonary Disease, Chronic Obstructive; Quinolones; Rats; Receptors, Adrenergic, beta-2; Structure-Activity Relationship

2014
Discovery of AZD3199, An Inhaled Ultralong Acting β2 Receptor Agonist with Rapid Onset of Action.
    ACS medicinal chemistry letters, 2014, Apr-10, Volume: 5, Issue:4

    Topics:

2014
The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist.
    Bioorganic & medicinal chemistry letters, 2014, Sep-01, Volume: 24, Issue:17

    Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Animals; Benzothiazoles; Dose-Response Relationship, Drug; Guinea Pigs; Molecular Structure; Receptors, Adrenergic, beta-2

2014
Structure-guided development of dual β2 adrenergic/dopamine D2 receptor agonists.
    Bioorganic & medicinal chemistry, 2016, 06-15, Volume: 24, Issue:12

    Topics: Adrenergic beta-2 Receptor Agonists; Animals; Benzoxazines; CHO Cells; Cricetulus; Dopamine Agonists; Drug Discovery; HEK293 Cells; Humans; Models, Molecular; Parkinson Disease; Polypharmacology; Receptors, Adrenergic, beta-2; Receptors, Dopamine D2

2016
Interactions between β2-Adrenoceptor Ligands and Membrane: Atomic-Level Insights from Magic-Angle Spinning NMR.
    Journal of medicinal chemistry, 2017, 08-24, Volume: 60, Issue:16

    Topics: Adrenergic beta-2 Receptor Agonists; Formoterol Fumarate; Hydrophobic and Hydrophilic Interactions; Indans; Ligands; Liposomes; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Quinolones; Salmeterol Xinafoate

2017
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009