formocresol and cresatin

This study was undertaken to determine the antibacterial effects of various endodontic medicaments against six selected anaerobic bacteria. The experiment involved the testing of the vapors of six medicaments using agar plates streaked with the bacteria. A zone of inhibition was recorded for each plate and the results were analyzed statistically. Formocresol produced significantly larger zones of inhibition than any of the other medicaments.

Topics: Analysis of Variance; Bacteria, Anaerobic; Chlorophenols; Cresols; Eugenol; Formocresols; Fusobacterium nucleatum; Glutaral; Lactobacillus; Microbial Sensitivity Tests; Peptococcus; Porphyromonas gingivalis; Potassium Iodide; Propionibacterium acnes; Root Canal Irrigants; Veillonella

Root canals of 21 maxillary human teeth were enlarged with reamers and flushed alternatively with sodium hypochlorite and hydrogen peroxide. After its mechanical preparation, root canals were dressed with camphorated paramonochloropherol and/or formocresol delivered by paper points. All three medicaments crystallize both on dentin walls and inside dentinal tubules. The clinical implications of these findings are discussed.

Topics: Adult; Cresols; Dental Pulp Cavity; Dentin; Dentin Permeability; Diffusion; Disinfectants; Formocresols; Humans; Microscopy, Electron, Scanning; Middle Aged; Phenol; Phenols; Root Canal Irrigants; Smear Layer

Topics: Adrenal Cortex Hormones; Adult; Animals; Balsams; Cresols; Drug Combinations; Edetic Acid; Formocresols; Gutta-Percha; Humans; Hydrogen Peroxide; Menthol; Root Canal Filling Materials; Root Canal Irrigants; Sodium Hypochlorite; Zinc Oxide; Zinc Oxide-Eugenol Cement

The tissue-irritating effect of anodyne medicaments was studied via enzyme histochemical evaluation of muscle tissue (screening test) and pulp tissue (usage test). Of the medicaments tested, formocresol was the most irritating, followed by Cresatin, eugenol, and oil of pimenta leaf. The effects of Cresatin, eugenol, and oil of pimenta leaf were not statistically distinguishable.

Topics: Animals; Biocompatible Materials; Condiments; Cresols; Dental Pulp; Dogs; Eugenol; Formocresols; L-Lactate Dehydrogenase; Muscles; Oils; Oils, Volatile; Rabbits; Root Canal Irrigants; Succinate Dehydrogenase