formic acid and serine

formic acid has been researched along with serine in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199021 (40.38)18.7374
1990's12 (23.08)18.2507
2000's7 (13.46)29.6817
2010's9 (17.31)24.3611
2020's3 (5.77)2.80

Authors

AuthorsStudies
Bottiglieri, T; Chanarin, I; Deacon, R; Lumb, M; Perry, J1
Braymer, HD; Shinabarger, DL1
Craig, G; Fahey, D; McCairns, E; Rowe, PB; Sauer, D1
Shane, B; Stokstad, EL1
Kubota, K1
Sheehan, TG; Tully, ER1
Ringø, E; Stenberg, E; Strøm, AR1
Sjöström, JE; Skogman, GS1
Dev, IK; Harvey, RJ1
Berens, RL; Fish, WR; Marr, JJ1
Berens, RL; Fish, WR; Looker, DL; Marr, JJ1
Appling, DR; Laude, DA; Pasternack, LB2
Nealson, KH; Scott, JH1
Appling, DR; García-Martínez, LF1
Arrese, M; Portela, A1
Bank, S; Miller, TL; Yan, B1
Hirano, H; Komatsu, S; Tsunasawa, S1
Appling, DR; Kastanos, E; Pasternack, LB; Woldman, YY1
Appling, DR; Kastanos, EK; Woldman, YY1
Kaiser, R; Metzka, L1
Buc, PS; Rolfes, RJ1
Gordon-Krajcer, W; Ksiezak-Reding, H; Yang, L1
Okudaira, M; Osanai, M1
Becker, S; Hartlieb, B; Kolesnikova, L; Konakova, T; Modrof, J; Möritz, C; Mühlberger, E; Randolf, A1
Fu, TF; Rife, JP; Schirch, V1
Weber, AL1
King, J; Li, R; Moore, M1
Chen, SW; Chistoserdova, L; Lapidus, A; Lidstrom, ME1
ARNSTEIN, HR; NEUBERGER, A1
BERG, P1
BILINSKI, E; McCONNELL, WB1
DOLE, VP; GLIEMANN, J1
HERSCOVICS, A; JOHNSTONE, RM1
AXELROD, AE; TRAKATELLIS, AC1
JOSEFSSON, L1
NESTER, EW; SPIZIZEN, J1
KRUHOFFER, P1
Alam, T; Hoshino, E; Hossain, MZ; Ikeda, T; Kuvatanasuchati, J; Uematsu, H1
SAKAMI, W1
Brosnan, JT; Brosnan, ME; Lamarre, SG; MacFarlane, AJ; MacMillan, L; Morrow, GP; Young, SK1
Baggott, JE; Tamura, T1
Doucette, AA; Zheng, S1
Chen, L; Ducker, GS; Esposito, M; Ghergurovich, JM; Kang, Y; Morscher, RJ; Rabinowitz, JD; Teng, X1
Brosnan, JT; Brosnan, ME; Clow, KA; MacMillan, L; Randell, EW; Tingley, G; Young, SK1
Atsumi, S; Hirano, S; Kondo, A; Matson, MM; Tashiro, Y1
Athineos, D; Blyth, K; Burgos-Barragan, G; Dhayade, S; Dornier, E; Mackay, GM; Meiser, J; Morton, JP; Niclou, SP; Oizel, K; Patel, KJ; Pietzke, M; Schuster, A; Sumpton, D; Vande Voorde, J; Vazquez, A; Wit, N1
Bar-Even, A; Bouzon, M; Döring, V; Yishai, O1
Bar-Even, A; Bouzon, M; Darii, E; Döring, V; Yishai, O1
Brosnan, JT; Brosnan, ME1
Athineos, D; Blyth, K; Falcone, M; Huerta Uribe, A; Maddocks, ODK; Newman, AC; Pietzke, M; Vazquez, A; Zhang, T1
Brosnan, JT; Brosnan, ME; Christian, SL; Gao, Y; Pongnopparat, T; Tingley, G1

Reviews

4 review(s) available for formic acid and serine

ArticleYear
Vitamin B12-folate interrelationships.
    Annual review of nutrition, 1985, Volume: 5

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic Acid; Folic Acid Deficiency; Formates; Formiminoglutamic Acid; Histidine; Homeostasis; Humans; Liver; Megaloblasts; Methionine; Methylation; Nitrous Oxide; Peptide Synthases; Pteroylpolyglutamic Acids; Purines; Serine; Thymidine Monophosphate; Thymidylate Synthase; Thyroid Gland; Vitamin B 12; Vitamin B 12 Deficiency

1985
Methylotrophy in Methylobacterium extorquens AM1 from a genomic point of view.
    Journal of bacteriology, 2003, Volume: 185, Issue:10

    Topics: Citric Acid Cycle; Formates; Genes, Bacterial; Genome, Bacterial; Glyoxylates; Hydroxybutyrates; Methanol; Methylamines; Methylobacterium extorquens; Oxidation-Reduction; Polyesters; Serine

2003
Folate-Dependent Purine Nucleotide Biosynthesis in Humans.
    Advances in nutrition (Bethesda, Md.), 2015, Volume: 6, Issue:5

    Topics: Carbon; Circadian Rhythm; Folic Acid; Formates; Glycine; Humans; Leucovorin; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Purine Nucleotides; Serine; Uric Acid

2015
Formate and its role in amino acid metabolism.
    Current opinion in clinical nutrition and metabolic care, 2020, Volume: 23, Issue:1

    Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Female; Formates; Humans; Mice; Multienzyme Complexes; Pregnancy; Serine; Transferases

2020

Other Studies

48 other study(ies) available for formic acid and serine

ArticleYear
Methylthioadenosine serves as a single carbon source to the folate co-enzyme pool in rat bone marrow cells.
    Biochimica et biophysica acta, 1990, Jun-20, Volume: 1034, Issue:3

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Bone Marrow; Carbon; Deoxyadenosines; Folic Acid; Formates; Glycine; Guanine; Male; Methionine; Methionine Adenosyltransferase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Serine; Thionucleosides

1990
Glyphosate catabolism by Pseudomonas sp. strain PG2982.
    Journal of bacteriology, 1986, Volume: 168, Issue:2

    Topics: Adenine; Bacterial Proteins; Formaldehyde; Formates; Glycine; Glyphosate; Guanine; Methionine; Oxidoreductases, N-Demethylating; Pseudomonas; Sarcosine; Sarcosine Oxidase; Serine

1986
One-carbon metabolism in lectin-activated human lymphocytes.
    Archives of biochemistry and biophysics, 1985, Volume: 236, Issue:1

    Topics: Blood Proteins; Carbon; Cells, Cultured; Choline; DNA; Formates; Glycine; Histidine; Humans; Lymphocyte Activation; Lymphocytes; Methionine; Purine Nucleotides; Purines; Pyrimidine Nucleotides; Pyrimidines; RNA; Serine; Thymine; Tryptophan

1985
Generation of formic acid and ethanolamine from serine in biosynthesis in linear gramicidin by a cell-free preparation of Bacillus brevis (ATCC 8185).
    Biochemical and biophysical research communications, 1982, Mar-30, Volume: 105, Issue:2

    Topics: Bacillus; Cell-Free System; Ethanolamine; Ethanolamines; Formates; Gramicidin; Serine; Valine

1982
Purine biosynthesis de novo in rat skeletal muscle.
    The Biochemical journal, 1983, Dec-15, Volume: 216, Issue:3

    Topics: Adenine; Adenosine; Animals; Azaserine; Cycloserine; Female; Formates; Glycine; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Muscles; Purines; Rats; Rats, Inbred Strains; Serine

1983
Trimethylamine oxide respiration of Alteromonas putrefaciens NCMB 1735: Na+-stimulated anaerobic transport in cells and membrane vesicles.
    Applied and environmental microbiology, 1984, Volume: 47, Issue:5

    Topics: Amino Acids; Anaerobiosis; Biological Transport, Active; Cell Membrane; Energy Metabolism; Energy Transfer; Formates; Gram-Negative Aerobic Bacteria; Lactates; Lactic Acid; Methylamines; Oxidation-Reduction; Serine; Sodium; Spheroplasts

1984
Factors affecting the biosynthesis of L-tryptophan by genetically modified strains of Escherichia coli.
    Journal of general microbiology, 1984, Volume: 130, Issue:12

    Topics: Escherichia coli; Formates; Glycine; Glycine Hydroxymethyltransferase; Indoles; Serine; Tryptophan; Tryptophan Synthase

1984
Sources of one-carbon units in the folate pathway of Escherichia coli.
    The Journal of biological chemistry, 1982, Feb-25, Volume: 257, Issue:4

    Topics: Amino Acids; Carbon Radioisotopes; Escherichia coli; Folic Acid; Formates; Glycine; Serine

1982
Purine metabolism in Trypanosoma brucei gambiense.
    Biochimica et biophysica acta, 1982, Feb-25, Volume: 714, Issue:3

    Topics: Formates; Glucose; Glycine; Guanine Deaminase; Purine Nucleosides; Purine Nucleotides; Purines; Serine; Trypanosoma brucei brucei

1982
Purine metabolism in the bloodstream forms of Trypanosoma gambiense and Trypanosoma rhodesiense.
    Biochimica et biophysica acta, 1982, Nov-24, Volume: 719, Issue:2

    Topics: Animals; Carbon Radioisotopes; Formates; Glucose; Glycine; Kinetics; Purine Nucleotides; Purines; Serine; Species Specificity; Trypanosoma; Trypanosoma brucei gambiense

1982
Whole-cell detection by 13C NMR of metabolic flux through the C1-tetrahydrofolate synthase/serine hydroxymethyltransferase enzyme system and effect of antifolate exposure in Saccharomyces cerevisiae.
    Biochemistry, 1994, Jun-14, Volume: 33, Issue:23

    Topics: Aminohydrolases; Carbon Isotopes; Folic Acid Antagonists; Formate-Tetrahydrofolate Ligase; Formates; Glycine Hydroxymethyltransferase; Magnetic Resonance Spectroscopy; Methylenetetrahydrofolate Dehydrogenase (NADP); Multienzyme Complexes; Saccharomyces cerevisiae; Serine

1994
A biochemical study of the intermediary carbon metabolism of Shewanella putrefaciens.
    Journal of bacteriology, 1994, Volume: 176, Issue:11

    Topics: Aerobiosis; Alcohol Oxidoreductases; Aldehyde-Lyases; Anaerobiosis; Bacteria; Carbon; Citric Acid Cycle; Formates; Glucose; Hydro-Lyases; Hydroxypyruvate Reductase; Models, Biological; Serine

1994
13C NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae.
    Biochemistry, 1994, Jan-11, Volume: 33, Issue:1

    Topics: Adenine; Carbon Isotopes; Choline; Formates; Genotype; Glycine; Guanine; Magnetic Resonance Spectroscopy; Models, Biological; Purines; Saccharomyces cerevisiae; Serine

1994
Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine.
    Biochemistry, 1993, May-04, Volume: 32, Issue:17

    Topics: Adenosine Diphosphate; Animals; Carbon Dioxide; Folic Acid; Formates; Formyltetrahydrofolates; Male; Mitochondria, Liver; NADP; Oligomycins; Oxidation-Reduction; Propionates; Rats; Rats, Sprague-Dawley; Serine

1993
Serine 3 is critical for phosphorylation at the N-terminal end of the nucleoprotein of influenza virus A/Victoria/3/75.
    Journal of virology, 1996, Volume: 70, Issue:6

    Topics: Amino Acid Sequence; Animals; Cell Line; Formates; Influenza A virus; Molecular Sequence Data; Mutation; Nucleocapsid Proteins; Nucleoproteins; Phosphorylation; RNA-Binding Proteins; Serine; Structure-Activity Relationship; Viral Core Proteins

1996
Solid 13C CPMAS NMR spectroscopy studies of biosynthesis in whole cells of Methanosphaera stadtmanae.
    Solid state nuclear magnetic resonance, 1996, Volume: 7, Issue:3

    Topics: Acetic Acid; Bacterial Proteins; Carbohydrate Metabolism; Carbohydrates; Carbon Dioxide; Carbon Isotopes; Euryarchaeota; Formates; Magnetic Resonance Spectroscopy; Nucleic Acids; Serine

1996
On-membrane deblocking of proteins.
    Methods in molecular biology (Clifton, N.J.), 1997, Volume: 64

    Topics: Formates; Membranes, Artificial; Polyvinyls; Protein Processing, Post-Translational; Proteins; Pyrrolidonecarboxylic Acid; Sequence Analysis; Serine; Threonine

1997
Use of 13C nuclear magnetic resonance to evaluate metabolic flux through folate one-carbon pools in Saccharomyces cerevisiae.
    Methods in enzymology, 1997, Volume: 281

    Topics: Carbon Isotopes; Choline; Folic Acid; Formates; Glycine; Leucovorin; Magnetic Resonance Spectroscopy; Purines; Saccharomyces cerevisiae; Serine

1997
Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae.
    Biochemistry, 1997, Dec-02, Volume: 36, Issue:48

    Topics: Carbon Isotopes; Cell Compartmentation; Cytoplasm; Folic Acid; Formates; Glycine; Glycine Hydroxymethyltransferase; Isoenzymes; Mitochondria; Nuclear Magnetic Resonance, Biomolecular; Purines; Saccharomyces cerevisiae; Serine

1997
Enhancement of cyanogen bromide cleavage yields for methionyl-serine and methionyl-threonine peptide bonds.
    Analytical biochemistry, 1999, Jan-01, Volume: 266, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cyanogen Bromide; Formates; Mass Spectrometry; Methionine; Peptides; Recombinant Proteins; Serine; Threonine; Water

1999
ade9 is an allele of SER1 and plays an indirect role in purine biosynthesis.
    Yeast (Chichester, England), 1999, Sep-30, Volume: 15, Issue:13

    Topics: Alleles; Formates; Gene Expression Regulation, Fungal; Genes, Fungal; Mutation; Purines; Saccharomyces cerevisiae; Serine; Transaminases

1999
Conformation of paired helical filaments blocks dephosphorylation of epitopes shared with fetal tau except Ser199/202 and Ser202/Thr205.
    Brain research, 2000, Feb-21, Volume: 856, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Alzheimer Disease; Amino Acid Sequence; Brain; Epitopes; Female; Fetus; Formates; Humans; Kinetics; Middle Aged; Neuropil Threads; Phosphorylation; Serine; tau Proteins; Threonine

2000
Syntheses of glycine and L-serine by their interconversion in the posterior silkgland of the silkworm, Bombyx mori.
    Amino acids, 2001, Volume: 20, Issue:2

    Topics: Animals; Bombyx; Carbon Isotopes; Fibroins; Formates; Glycine; Isotope Labeling; Magnetic Resonance Spectroscopy; Organ Culture Techniques; Serine; Tetrahydrofolates

2001
Phosphorylation of Marburg virus VP30 at serines 40 and 42 is critical for its interaction with NP inclusions.
    Virology, 2001, Aug-15, Volume: 287, Issue:1

    Topics: Alkaline Phosphatase; Amino Acid Substitution; Animals; Chlorocebus aethiops; Cloning, Molecular; Formates; HeLa Cells; Humans; Inclusion Bodies, Viral; Microscopy, Immunoelectron; Mutagenesis, Site-Directed; Nucleocapsid Proteins; Phosphoamino Acids; Phosphorylation; Serine; Structure-Activity Relationship; Transfection; Vero Cells; Viral Proteins

2001
The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR.
    Archives of biochemistry and biophysics, 2001, Sep-01, Volume: 393, Issue:1

    Topics: Breast Neoplasms; Carbon Isotopes; Cytosol; Female; Formates; Glycine; Glycine Hydroxymethyltransferase; Humans; Isoenzymes; Magnetic Resonance Spectroscopy; Mitochondria; Models, Biological; Purines; Serine; Substrate Specificity; Thymidine Monophosphate; Tumor Cells, Cultured

2001
Alanine synthesis from glyceraldehyde and ammonium ion in aqueous solution.
    Journal of molecular evolution, 1985, Volume: 21

    Topics: Acetylcysteine; Alanine; Evolution, Chemical; Evolution, Molecular; Formates; Glyceraldehyde; Glycine; Glycolates; Lactic Acid; Quaternary Ammonium Compounds; Serine; Sulfhydryl Compounds

1985
Investigating the regulation of one-carbon metabolism in Arabidopsis thaliana.
    Plant & cell physiology, 2003, Volume: 44, Issue:3

    Topics: Aminohydrolases; Arabidopsis; Carbon; Carbon Dioxide; Carbon Isotopes; Formate Dehydrogenases; Formate-Tetrahydrofolate Ligase; Formates; Gene Expression Regulation, Enzymologic; Glycine; Glycine Hydroxymethyltransferase; Homocysteine S-Methyltransferase; Magnetic Resonance Spectroscopy; Methylenetetrahydrofolate Dehydrogenase (NADP); Methyltransferases; Multienzyme Complexes; Mutation; Plant Shoots; Plants, Genetically Modified; Serine

2003
The effect of cobalamin on the quantitative utilization of serine, glycine and formate for the synthesis of choline and methyl groups of methionine.
    The Biochemical journal, 1953, Volume: 55, Issue:2

    Topics: Choline; Fabaceae; Formates; Glycine; Hematinics; Methionine; Serine; Vitamin B 12

1953
A study of formate utilization in pigeon liver extract.
    The Journal of biological chemistry, 1953, Volume: 205, Issue:1

    Topics: Animals; Columbidae; Formates; Liver; Liver Extracts; Methionine; Serine

1953
Studies on wheat plants using carbon-14 compounds. IX. Radioactivity of wheat following injection of formate-C14 and glycine-1-C14 with special reference to serine labelling.
    Canadian journal of biochemistry and physiology, 1959, Volume: 37, Issue:4

    Topics: Carbon Radioisotopes; Dietary Fats, Unsaturated; Fabaceae; Formates; Glycine; Radioactivity; Serine; Triticum

1959
INCORPORATION OF FORMATE INTO LIPIDS OF ADIPOSE TISSUE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Acetates; Adipose Tissue; Amino Acids; Carbon Isotopes; Fatty Acids; Formates; Glucose; Glycerides; Glycerol; Insulin; Lipid Metabolism; Lipids; Metabolism; Pharmacology; Research; RNA; Serine

1964
MECHANISM OF ACTION OF GLUCOSE AND PYRIMIDINE NUCLEOSIDES ON (14C)FORMATE UTILIZATION BY EHRLICH ASCITES CELLS.
    Biochimica et biophysica acta, 1964, Nov-15, Volume: 91

    Topics: Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Formates; Glucose; Glutamine; Metabolism; Nucleosides; Nucleotides; Proteins; Pyrimidine Nucleosides; Research; Serine; Tissue Culture Techniques; Uridine

1964
EFFECT OF PYRIDOXINE DEFICIENCY ON NUCLEIC ACID METABOLISM IN THE RAT.
    The Biochemical journal, 1965, Volume: 95

    Topics: Adenine; DNA; Formates; Liver; Metabolism; Methionine; Nucleic Acids; Nucleosides; Pyridoxal Phosphate; Rats; Research; RNA; Serine; Spleen; Thymidine; Transferases; Vitamin B 6 Deficiency

1965
A study of the volume change in the acyl shift with regard to the formic acid inactivation of protein enzymes.
    Biochimica et biophysica acta, 1962, Apr-23, Volume: 58

    Topics: Formates; Serine

1962
Role of one-carbon precursors in the biosynthesis of deoxyribonucleic acid in bacteriophage infected and growing cells of Escherichia coli.
    Journal of bacteriology, 1961, Volume: 82

    Topics: Bacteriological Techniques; Bacteriophages; Carbon; Carbon Isotopes; DNA; Escherichia coli; Formates; Glycine; Purines; Pyrimidines; Serine

1961
On the role played by formate in serine biosynthesis.
    The Biochemical journal, 1951, Volume: 48, Issue:5

    Topics: Formates; Serine

1951
Degradation of serine-containing oligopeptides by Peptostreptococcus micros ATCC 33270.
    Oral microbiology and immunology, 2007, Volume: 22, Issue:6

    Topics: Acetate Kinase; Acetates; Acetyltransferases; Adenosine Triphosphate; Ammonia; Formate Dehydrogenases; Formates; Humans; L-Serine Dehydratase; Oligopeptides; Peptostreptococcus; Phosphate Acetyltransferase; Pyruvate Synthase; Pyruvic Acid; Serine; Tyrosine

2007
The conversion of formate and glycine to serine and glycogen in the intact rat.
    The Journal of biological chemistry, 1948, Volume: 176, Issue:2

    Topics: Animals; Formates; Glycine; Glycogen; Rats; Serine

1948
In vivo kinetics of formate metabolism in folate-deficient and folate-replete rats.
    The Journal of biological chemistry, 2015, Jan-23, Volume: 290, Issue:4

    Topics: Animals; Choline; Dimethylglycine Dehydrogenase; Folic Acid; Folic Acid Deficiency; Formaldehyde; Formates; Glycine; Histidine; Liver; Male; Methionine; Mitochondria; Mitochondria, Liver; Oxygen; Rats; Rats, Sprague-Dawley; Sarcosine Dehydrogenase; Serine; Tetrahydrofolates

2015
Preventing N- and O-formylation of proteins when incubated in concentrated formic acid.
    Proteomics, 2016, Volume: 16, Issue:7

    Topics: Escherichia coli Proteins; Formates; Histones; Humans; Peptide Fragments; Proteomics; Serine; Solubility; Tandem Mass Spectrometry; Threonine

2016
Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.
    Cell metabolism, 2016, 06-14, Volume: 23, Issue:6

    Topics: Aminoimidazole Carboxamide; Carbon; Cell Compartmentation; Cell Proliferation; Colonic Neoplasms; CRISPR-Cas Systems; Cytosol; Folic Acid; Formates; Gene Knockout Techniques; Gene Library; Glycine; Glycine Hydroxymethyltransferase; HCT116 Cells; HEK293 Cells; Humans; Leucovorin; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Mutation; NADP; Ribonucleotides; Serine; Xenograft Model Antitumor Assays

2016
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
    The Journal of nutrition, 2018, 03-01, Volume: 148, Issue:3

    Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Random Allocation; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcosine; Serine; Vitamin B 12; Vitamin B 12 Deficiency

2018
Electrical-biological hybrid system for CO
    Metabolic engineering, 2018, Volume: 47

    Topics: Carbon Dioxide; Escherichia coli; Formates; Glycine; Metabolic Engineering; Microorganisms, Genetically-Modified; Oxidation-Reduction; Pyruvic Acid; Serine

2018
Increased formate overflow is a hallmark of oxidative cancer.
    Nature communications, 2018, 04-10, Volume: 9, Issue:1

    Topics: Adenoma; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Female; Formates; Gene Expression Regulation, Neoplastic; Glycine Hydroxymethyltransferase; Intestinal Mucosa; Intestinal Neoplasms; Intestines; Isoenzymes; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methotrexate; Mice; Mice, Inbred C57BL; Mitochondria; Oxidation-Reduction; Serine; Tumor Microenvironment

2018
In Vivo Assimilation of One-Carbon via a Synthetic Reductive Glycine Pathway in Escherichia coli.
    ACS synthetic biology, 2018, 09-21, Volume: 7, Issue:9

    Topics: Amino Acid Oxidoreductases; Carbon; Carbon Dioxide; Carrier Proteins; Escherichia coli; Formates; Glycine; Multienzyme Complexes; Serine; Tetrahydrofolates; Transferases

2018
Implementation of a Reductive Route of One-Carbon Assimilation in Escherichia coli through Directed Evolution.
    ACS synthetic biology, 2018, 09-21, Volume: 7, Issue:9

    Topics: Carbon; Carbon Dioxide; Carbon Isotopes; Chromatography, High Pressure Liquid; Directed Molecular Evolution; Escherichia coli; Formates; Glutathione; Serine; Tandem Mass Spectrometry

2018
Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells.
    Molecular cell, 2021, 06-03, Volume: 81, Issue:11

    Topics: Allografts; Animals; Antineoplastic Agents; Carbon; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Formates; Gene Expression Regulation, Neoplastic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Nude; Oximes; Pancreatic Neoplasms; Pancreatic Stellate Cells; Proto-Oncogene Proteins p21(ras); Serine; Signal Transduction; Sulfonamides; Tryptophan; Tumor Escape; Tumor Suppressor Protein p53

2021
Oncogenic Ras expression increases cellular formate production.
    Amino acids, 2021, Volume: 53, Issue:10

    Topics: Aminohydrolases; Animals; Formate-Tetrahydrofolate Ligase; Formates; Gene Expression Regulation; Genes, ras; Glycine; Glycine Hydroxymethyltransferase; Methenyltetrahydrofolate Cyclohydrolase; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Multienzyme Complexes; Multifunctional Enzymes; NIH 3T3 Cells; ras Proteins; RNA, Messenger; Serine

2021