formic acid has been researched along with methotrexate in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Agarwal, RP; Bruce-Gregorios, JH; Lin, L; Oracion, A; Ramirez, A | 1 |
| Allegra, CJ; Baram, J; Drake, JC | 1 |
| Goldman, ID; Rape, TJ; Seither, RL | 1 |
| Goldman, ID; Mikulecky, DC; Rape, TJ; Seither, RL; Trent, DF | 1 |
| Black, KA; Tephly, TR | 1 |
| González-Quevedo, A; Lima, L; Obregón, F; Roussó, T; Urbina, M | 1 |
| GOLDIN, A; LYNCH, MR; MEAD, JA; SCHRECKER, AW; VENDITTI, JM | 1 |
| GOLDIN, A; MEAD, JA; SCHRECKER, AW | 1 |
| BERTINO, JR; DONOHUE, DM; SIMMONS, B | 1 |
| Muthuvel, A; Rajamani, R; Senthilvelan, M; Sheeladevi, R | 1 |
| Athineos, D; Blyth, K; Burgos-Barragan, G; Dhayade, S; Dornier, E; Mackay, GM; Meiser, J; Morton, JP; Niclou, SP; Oizel, K; Patel, KJ; Pietzke, M; Schuster, A; Sumpton, D; Vande Voorde, J; Vazquez, A; Wit, N | 1 |
| Blenis, J; Cantley, LC; Cheng, Z; Fei, DL; Lee, G; Li, Q; Lin, TY; Momb, J; Paddock, MN; Ramsamooj, S; Stein, BD; Zhang, G; Zheng, Y | 1 |
| Chen, DY; Chen, YM; Chiang, EI; Chih, HM; Fan, YH; Huang, WN; Huang, YH; Ko, HA; Lin, YY; Shane, B; Sou, NL; Tang, FY; Wang, YC | 1 |
13 other study(ies) available for formic acid and methotrexate
| Article | Year |
|---|---|
Effects of methotrexate on RNA and purine synthesis of astrocytes in primary culture.
Topics: Animals; Astrocytes; Formates; Glycine; Methotrexate; Purine Nucleotides; Rats; RNA; Tritium; Uridine | 1991 |
Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells.
Topics: Adenosine Triphosphate; Breast Neoplasms; Chromatography, High Pressure Liquid; Cytoplasm; Folic Acid; Formates; Humans; Kinetics; Magnesium; Methotrexate; Tumor Cells, Cultured | 1990 |
Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell.
Topics: Animals; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Formates; Leucovorin; Leukemia L1210; Methotrexate; Mice; Polyglutamic Acid; Tumor Cells, Cultured | 1989 |
Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells.
Topics: Animals; Computer Simulation; Deoxyuridine; Floxuridine; Folic Acid; Folic Acid Antagonists; Formates; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimidines; Quinazolines; Tetrahydrofolates; Thermodynamics; Thymidylate Synthase; Trimetrexate | 1989 |
Effects of nitrous oxide and methotrexate administration on hepatic methionine synthetase and dihydrofolate reductase activities, hepatic folates, and formate oxidation in rats.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Folic Acid; Formates; Kinetics; Liver; Male; Methotrexate; Methyltransferases; Nitrous Oxide; Rats; Rats, Inbred Strains; Tetrahydrofolate Dehydrogenase | 1983 |
Effect of chronic methanol administration on amino acids and monoamines in retina, optic nerve, and brain of the rat.
Topics: Amino Acids; Animals; Biogenic Monoamines; Brain; Cerebral Cortex; Formates; Hippocampus; Male; Methanol; Methotrexate; Neurotransmitter Agents; Optic Nerve; Rats; Rats, Sprague-Dawley; Retina | 2002 |
Effect of orally administered 3', 5'-dichloroamethopterin on formate-C14 incorporation in leukemic mice.
Topics: Animals; Antineoplastic Agents; Folic Acid Antagonists; Formates; Leukemia, Experimental; Methotrexate; Mice | 1960 |
Incorporation of formate-C-14 in normal and leukemic mice during extended treatment with amethopterin and 3',5'-dichloramethopterin.
Topics: Animals; Folic Acid Antagonists; Formates; Leukemia, Experimental; Liver; Methotrexate; Mice; Spleen | 1962 |
LEVELS OF DIHYDROFOLATE REDUCTASE AND THE FORMATE-ACTIVATING ENZYME ACTIVITIES IN GUINEA PIG TISSUES BEFORE AND AFTER AMETHOPTERIN ADMINISTRATION.
Topics: Animals; Bone Marrow; Brain; Erythrocytes; Female; Formates; Guinea Pigs; Humans; Intestine, Small; Intestines; Kidney; Leukocytes; Liver; Metabolism; Methotrexate; Muscles; Ovary; Oxidoreductases; Pharmacology; Research; Spleen; Tetrahydrofolate Dehydrogenase | 1964 |
Oxidative stress induced by methotrexate alone and in the presence of methanol in discrete regions of the rodent brain, retina and optic nerve.
Topics: Animals; Brain; Catalase; Drug Therapy, Combination; Formates; Formiminoglutamic Acid; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; HSP70 Heat-Shock Proteins; Lipid Peroxidation; Male; Methanol; Methotrexate; Optic Nerve; Oxidative Stress; Rats; Rats, Wistar; Retina; Sulfhydryl Compounds; Superoxide Dismutase | 2006 |
Increased formate overflow is a hallmark of oxidative cancer.
Topics: Adenoma; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Female; Formates; Gene Expression Regulation, Neoplastic; Glycine Hydroxymethyltransferase; Intestinal Mucosa; Intestinal Neoplasms; Intestines; Isoenzymes; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methotrexate; Mice; Mice, Inbred C57BL; Mitochondria; Oxidation-Reduction; Serine; Tumor Microenvironment | 2018 |
Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells.
Topics: Carbon; Cytosol; Formates; HCT116 Cells; HeLa Cells; Humans; MCF-7 Cells; Methotrexate; Mitochondria; Mitochondrial Proteins; Neoplasm Proteins; Neoplasms; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 2018 |
Folinate Supplementation Ameliorates Methotrexate Induced Mitochondrial Formate Depletion In Vitro and In Vivo.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Dietary Supplements; Female; Formates; Humans; Leucovorin; Metabolic Networks and Pathways; Methotrexate; Mice, Inbred C57BL; Mitochondria; Vitamin B Complex | 2021 |